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Minerva Biotecnologica最新文献

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Predicted peptide-based MHC-I, MHC-II, CTL and B-cell epitopes of MUC-1 by immunoinformatics methods: a clue for novel multi-epitope vaccine development against breast cancer 利用免疫信息学方法预测MUC-1的MHC-I、MHC-II、CTL和b细胞表位:为开发新型乳腺癌多表位疫苗提供线索
IF 0.9
Minerva Biotecnologica Pub Date : 2021-02-03 DOI: 10.23736/S1120-4826.19.02598-9
Pejman Hashemzadeh, V. Ghorbanzadeh, H. Dariushnejad
{"title":"Predicted peptide-based MHC-I, MHC-II, CTL and B-cell epitopes of MUC-1 by immunoinformatics methods: a clue for novel multi-epitope vaccine development against breast cancer","authors":"Pejman Hashemzadeh, V. Ghorbanzadeh, H. Dariushnejad","doi":"10.23736/S1120-4826.19.02598-9","DOIUrl":"https://doi.org/10.23736/S1120-4826.19.02598-9","url":null,"abstract":"BACKGROUND: Breast cancer (BC) is one of the most common types of women malignancy. Multi-epitope vaccines are new hopes for treatment of this cancer. MUC-1 is a tumor associated antigen that focused for multi-epitope vaccine development in case of BC. \u0000METHODS: Here, primary data from a computation analysis of this glycoprotein to find potential MHC-I, MHC-II, CTL and B-cell epitopes are described using immunoinformatics tools. \u0000RESULTS: According to the results, 1156VPGWGIALL984 corresponding to HLA-B0702 and HLA-A0101 alleles for MHC-I epitopes, 1209YPTYHTHGR1118 corresponding to DRB1*13 and DQB1*06 alleles for MHC-II epitops, 1122NQYKTEAAS45 for CTL epitopes and 1204HPMSEYPTYHTHGRYV896 for B-cell epitopes are the peptides with the best binding affinity. \u0000CONCLUSIONS: These data may be useful for further multi-epitope vaccine development. \u0000 \u0000 \u0000KEY WORDS: Breast neoplasms; Epitopes; Vaccines, synthetic; Mucin-1","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"1 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86509839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification and analysis of key regulatory genes associated with pre-eclampsia: a systems biology approach 鉴定和分析与先兆子痫相关的关键调控基因:系统生物学方法
IF 0.9
Minerva Biotecnologica Pub Date : 2021-01-01 DOI: 10.23736/S1120-4826.20.02687-7
Lin Lin, Xiaoqian Lin, Zhaodong Liu, HuaLe Zhang, Q. Han, Rongxin Chen, Lichun Chen, Jianying Yan
{"title":"Identification and analysis of key regulatory genes associated with pre-eclampsia: a systems biology approach","authors":"Lin Lin, Xiaoqian Lin, Zhaodong Liu, HuaLe Zhang, Q. Han, Rongxin Chen, Lichun Chen, Jianying Yan","doi":"10.23736/S1120-4826.20.02687-7","DOIUrl":"https://doi.org/10.23736/S1120-4826.20.02687-7","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"22 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75111125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance of cytokeratin-18 apoptotic fragment for the identification of hepatic fibrosis and inflammation in patients with chronic viral hepatitis: a meta-analysis 细胞角蛋白-18凋亡片段在慢性病毒性肝炎患者肝纤维化和炎症鉴定中的作用:一项meta分析
IF 0.9
Minerva Biotecnologica Pub Date : 2021-01-01 DOI: 10.23736/S1120-4826.20.02681-6
C. Rosso, G. P. Caviglia, A. Armandi, M. Abate, A. Olivero, D. Ribaldone, R. Pellicano, G. Saracco, E. Bugianesi
{"title":"Performance of cytokeratin-18 apoptotic fragment for the identification of hepatic fibrosis and inflammation in patients with chronic viral hepatitis: a meta-analysis","authors":"C. Rosso, G. P. Caviglia, A. Armandi, M. Abate, A. Olivero, D. Ribaldone, R. Pellicano, G. Saracco, E. Bugianesi","doi":"10.23736/S1120-4826.20.02681-6","DOIUrl":"https://doi.org/10.23736/S1120-4826.20.02681-6","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"16 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84154971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular methods for the detection of Helicobacter pylori 幽门螺杆菌的分子检测方法
IF 0.9
Minerva Biotecnologica Pub Date : 2021-01-01 DOI: 10.23736/S1120-4826.20.02665-8
G. Isaeva, R. Isaeva
{"title":"Molecular methods for the detection of Helicobacter pylori","authors":"G. Isaeva, R. Isaeva","doi":"10.23736/S1120-4826.20.02665-8","DOIUrl":"https://doi.org/10.23736/S1120-4826.20.02665-8","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"18 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81705191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Seronegative occult hepatitis C virus infection: what is its clinical relevance? 血清阴性隐匿性丙型肝炎病毒感染:其临床相关性是什么?
IF 0.9
Minerva Biotecnologica Pub Date : 2021-01-01 DOI: 10.23736/S1120-4826.20.02637-3
A. Armandi, G. P. Caviglia, G. Saracco, L. Marco, S. Fagoonee, R. Pellicano
{"title":"Seronegative occult hepatitis C virus infection: what is its clinical relevance?","authors":"A. Armandi, G. P. Caviglia, G. Saracco, L. Marco, S. Fagoonee, R. Pellicano","doi":"10.23736/S1120-4826.20.02637-3","DOIUrl":"https://doi.org/10.23736/S1120-4826.20.02637-3","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"22 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78965765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monocyte-derived microparticles stimulate alveolar macrophages from patients with sarcoidosis: modulation by PPARγ 单核细胞来源的微粒刺激结节病患者的肺泡巨噬细胞:PPARγ的调节
IF 0.9
Minerva Biotecnologica Pub Date : 2021-01-01 DOI: 10.23736/S1120-4826.20.02632-4
A. Amoruso, P. Balbo, F. Patrucco, F. Gavelli, L. Castello, C. Bardelli, T. Neri, A. Celi, Valentina Foci, L. Fresu, S. Brunelleschi
{"title":"Monocyte-derived microparticles stimulate alveolar macrophages from patients with sarcoidosis: modulation by PPARγ","authors":"A. Amoruso, P. Balbo, F. Patrucco, F. Gavelli, L. Castello, C. Bardelli, T. Neri, A. Celi, Valentina Foci, L. Fresu, S. Brunelleschi","doi":"10.23736/S1120-4826.20.02632-4","DOIUrl":"https://doi.org/10.23736/S1120-4826.20.02632-4","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"311 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75336326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In silico analysis based on constituents of the medicinal plant Xuebijing (XBJ) to identify candidate treatment agents for sepsis in the omics-driven research era 基于药用植物血必净(XBJ)成分的硅片分析，在组学驱动的研究时代确定脓毒症的候选治疗药物
IF 0.9
Minerva Biotecnologica Pub Date : 2021-01-01 DOI: 10.23736/S1120-4826.20.02684-1
Zhenyu Xu, Na Yin, R. Ren, Z. Ruan
{"title":"In silico analysis based on constituents of the medicinal plant Xuebijing (XBJ) to identify candidate treatment agents for sepsis in the omics-driven research era","authors":"Zhenyu Xu, Na Yin, R. Ren, Z. Ruan","doi":"10.23736/S1120-4826.20.02684-1","DOIUrl":"https://doi.org/10.23736/S1120-4826.20.02684-1","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"227 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75760673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete genome sequence of mcr-1-harboring Escherichia coli discovered from Mink 水貂携带mcr-1大肠杆菌的全基因组序列
IF 0.9
Minerva Biotecnologica Pub Date : 2021-01-01 DOI: 10.23736/S1120-4826.20.02649-X
Xinxing Wang, Hongna Zhang, Xiaonan Zhao, Zhenzhen Zhai, Zijing Ju, J. Peng, Qiaoyun Wang, Weishan Chang
{"title":"Complete genome sequence of mcr-1-harboring Escherichia coli discovered from Mink","authors":"Xinxing Wang, Hongna Zhang, Xiaonan Zhao, Zhenzhen Zhai, Zijing Ju, J. Peng, Qiaoyun Wang, Weishan Chang","doi":"10.23736/S1120-4826.20.02649-X","DOIUrl":"https://doi.org/10.23736/S1120-4826.20.02649-X","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"6 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79158998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Preparation of carbon dot as a potential CRISPR/Cas9 plasmid delivery system for lung cancer cells 碳点作为潜在的肺癌细胞CRISPR/Cas9质粒传递系统的制备
IF 0.9
Minerva Biotecnologica Pub Date : 2020-07-01 DOI: 10.23736/s1120-4826.20.02618-x
R. Mohammadinejad, A. Dehshahri, H. Sassan, B. Behnam, M. Ashrafizadeh, Azadeh Samareh Gholami, A. Pardakhty, A. Mandegary
{"title":"Preparation of carbon dot as a potential CRISPR/Cas9 plasmid delivery system for lung cancer cells","authors":"R. Mohammadinejad, A. Dehshahri, H. Sassan, B. Behnam, M. Ashrafizadeh, Azadeh Samareh Gholami, A. Pardakhty, A. Mandegary","doi":"10.23736/s1120-4826.20.02618-x","DOIUrl":"https://doi.org/10.23736/s1120-4826.20.02618-x","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"111 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79627766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Plasma microvesicles in patients admitted to the emergency department for mild traumatic brain injury: first clues to understand their role 急诊科收治的轻度创伤性脑损伤患者的血浆微泡:了解其作用的第一个线索
IF 0.9
Minerva Biotecnologica Pub Date : 2020-07-01 DOI: 10.23736/s1120-4826.20.02626-9
L. Salmi, F. Gavelli, C. A. Gardino, D. Medica, F. Patrucco, M. Bellan, P. Sainaghi, R. Vaschetto, F. Della Corte, C. Smirne, A. Benech, M. Brucoli, G. Avanzi, V. Cantaluppi, L. Castello
{"title":"Plasma microvesicles in patients admitted to the emergency department for mild traumatic brain injury: first clues to understand their role","authors":"L. Salmi, F. Gavelli, C. A. Gardino, D. Medica, F. Patrucco, M. Bellan, P. Sainaghi, R. Vaschetto, F. Della Corte, C. Smirne, A. Benech, M. Brucoli, G. Avanzi, V. Cantaluppi, L. Castello","doi":"10.23736/s1120-4826.20.02626-9","DOIUrl":"https://doi.org/10.23736/s1120-4826.20.02626-9","url":null,"abstract":"","PeriodicalId":54738,"journal":{"name":"Minerva Biotecnologica","volume":"62 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88907390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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