International Journal of Probiotics and Prebiotics最新文献

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Health Benefits of a Combination Probiotics; FlorMidabil™ 复合益生菌对健康的益处FlorMidabil™
International Journal of Probiotics and Prebiotics Pub Date : 2019-03-09 DOI: 10.37290/ijpp2641-7197.14:9-17
S. Latvala, S. Philipp, M. Lehtinen, L. Lehtoranta, A. Ouwehand
{"title":"Health Benefits of a Combination Probiotics; FlorMidabil™","authors":"S. Latvala, S. Philipp, M. Lehtinen, L. Lehtoranta, A. Ouwehand","doi":"10.37290/ijpp2641-7197.14:9-17","DOIUrl":"https://doi.org/10.37290/ijpp2641-7197.14:9-17","url":null,"abstract":"This review summarizes health benefits of a combination of a four-strain probiotic consisting of L. paracasei Lpc-37, B. lactis Bl-04, L. acidophilus La-14, and L. plantarum Lp-115. The safety of the individual strains for absence of transferable antibiotic resistance and adverse events in human intervention studies has been documented. The strains have been shown, both in vitro and in human studies, to survive gastro-intestinal transit and transiently colonize the intestine in a dose-dependent manner. In digestive health, the strains have shown to modulate the intestinal microbiota and reduce risk for both diarrhea and constipation. In vitro, animal and human studies have shown these strains to positively modulate many immune markers, in particular anti-inflammatory markers. These modifications also suggest a reduced risk for respiratory tract infections and seasonal respiratory allergies. The strains contributed positively to weight management in humans and reduced markers of metabolic syndrome in animal models. Finally, one of the strains (L. acidophilus La-14) was shown to colonize the vagina and contribute to reduced risk for recurrent bacterial vaginosis, vulvovaginal candidiasis and urinary tract infection. The combination of these four strains can therefore be expected to provide a broad spectrum of health benefits.","PeriodicalId":53704,"journal":{"name":"International Journal of Probiotics and Prebiotics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46882948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Consumption of Probiotic Powder Containing Lactobacillus Plantarum Dad-13 on Fecal Bacterial Population in School-Age Children in Indonesia 食用含有植物乳杆菌Dad-13的益生菌粉对印度尼西亚学龄儿童粪便细菌数量的影响
International Journal of Probiotics and Prebiotics Pub Date : 2019-01-29 DOI: 10.37290/ijpp2641-7197.14:1-8
Banin Maghfirotin Marta, U. Tyas, Cahyanto Muhammad Nur, Widada Jaka, Rahayu Endang Sutriswati
{"title":"Effects of Consumption of Probiotic Powder Containing Lactobacillus Plantarum Dad-13 on Fecal Bacterial Population in School-Age Children in Indonesia","authors":"Banin Maghfirotin Marta, U. Tyas, Cahyanto Muhammad Nur, Widada Jaka, Rahayu Endang Sutriswati","doi":"10.37290/ijpp2641-7197.14:1-8","DOIUrl":"https://doi.org/10.37290/ijpp2641-7197.14:1-8","url":null,"abstract":"Consumption of probiotics is known to influence the gut microbiota. The aim of this study was to assess the effect of probiotic powder containing Lactobacillus plantarum Dad-13 on bacterial composition in the gut by examining fecal samples of school-age children in Yogyakarta, Indonesia. This is a randomized, double-blind, placebo-controlled study. A total of 40 healthy subjects were recruited for this study and were divided into two groups: placebo group and probiotic group. The placebo group consumed skim milk and the probiotic group consumed probiotic powder containing L. plantarum Dad-13 (2 × 109 CFU/g) for 65 days. The results showed that placebo intake had no significant effect on gut microbiota; however, probiotic caused a significant increase in L. plantarum and Lactobacillus population, while decreasing the population of E. coli and non-E. coli coliform bacteria by 55% and 75%, respectively and Bifidobacteria count did not change significantly. The study concluded that consumption of probiotic powder L. plantarum Dad-13 could increase propionic acid thereby decreasing the gut pH which has an effect on the microbial population.","PeriodicalId":53704,"journal":{"name":"International Journal of Probiotics and Prebiotics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48663390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
BIOAVAILABILITY OF BIOTRANSFORMED ZINC ENRICHED DAHI IN WISTAR RATS. 生物转化富锌鱼粉在wistar大鼠体内的生物利用度。
Jagan Mohan, Syed Azmal Ali, Ranvir Suvartan, Suman Kapila, Rajan Sharma, Sudhir Kumar Tomar, Pradip Behare, Hariom Yadav
{"title":"BIOAVAILABILITY OF BIOTRANSFORMED ZINC ENRICHED DAHI IN WISTAR RATS.","authors":"Jagan Mohan, Syed Azmal Ali, Ranvir Suvartan, Suman Kapila, Rajan Sharma, Sudhir Kumar Tomar, Pradip Behare, Hariom Yadav","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present study, we have investigated the bioavailability of biotransformed organic zinc enriched dahi in vivo. The results evidence that the rats fed with zinc enriched dahi (ZED and ZEP) significantly increased (p<0.001) body weight and food intake from zero to third weeks. Analysis of zinc by AAS in body parts of different rat groups indicated that zinc content was significantly higher (p<0.001) in serum, femur bone, liver and hair of rats fed ZED/ZEP. Basal diet and inorganic zinc sulphate fed rat group excreted a greater amount of zinc in faeces. The results of in-vivo studies indicated that the bioavailability of organic zinc through dahi/probiotic dahi is high compared to its inorganic form.</p>","PeriodicalId":53704,"journal":{"name":"International Journal of Probiotics and Prebiotics","volume":"13 2-3","pages":"45-54"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic profiling of a chronic kidney disease cohort reveals metabolic phenotype more likely to benefit from a probiotic. 慢性肾脏疾病队列的代谢分析显示代谢表型更可能受益于益生菌。
International Journal of Probiotics and Prebiotics Pub Date : 2017-01-01 Epub Date: 2017-08-21
Subodh J Saggi, Kelly Mercier, Jessica R Gooding, Eli Friedman, Usha Vyas, Natarajan Ranganathan, Pari Ranganathan, Susan McRitchie, Susan Sumner
{"title":"Metabolic profiling of a chronic kidney disease cohort reveals metabolic phenotype more likely to benefit from a probiotic.","authors":"Subodh J Saggi,&nbsp;Kelly Mercier,&nbsp;Jessica R Gooding,&nbsp;Eli Friedman,&nbsp;Usha Vyas,&nbsp;Natarajan Ranganathan,&nbsp;Pari Ranganathan,&nbsp;Susan McRitchie,&nbsp;Susan Sumner","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Scope: </strong>Persistent reduction in Glomerular Filtration Rate (GFR) is a hallmark of Chronic Kidney Disease (CKD) and is associated with an elevation of Blood Urea Nitrogen (BUN). This metabolomics pilot study sought to identify metabolites that differentiated patients with CKD whose BUN decreased on a probiotic and possible mechanisms.</p><p><strong>Methods and results: </strong>Metabolomics was used to analyze baseline plasma samples previously diagnosed with CKD Stage III-IV. Patients had participated in a dose escalation study of the probiotic Renadyl™. A total of 24 samples were categorized depending on whether BUN increased or decreased from baseline after 4 months of probiotic use. Multivariate analysis was used to analyze the data and determine the metabolites that best differentiated the phenotypic groups. The sixteen patients who had a decrease in BUN were not significantly different based on demographic and clinical measures from those whose BUN increased or did not change with the exception of age. Eleven of the fourteen metabolites that differentiated the groups were known to be modulated by gut microflora, which may eventually provide a mechanistic link between probiotic and outcomes.</p><p><strong>Conclusions: </strong>Metabolomics revealed metabolites at baseline that may predict individuals with CKD that would most benefit from a probiotics.</p>","PeriodicalId":53704,"journal":{"name":"International Journal of Probiotics and Prebiotics","volume":"12 1","pages":"43-54"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377160/pdf/nihms-982105.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36974280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PROBIOTICS - A PROBABLE THERAPEUTIC AGENT FOR SPONDYLOARTHROPATHY. 益生菌-脊椎关节病的可能治疗剂。
International Journal of Probiotics and Prebiotics Pub Date : 2017-01-01 Epub Date: 2017-08-21
Nandini Singh, Hariom Yadav, Francesco Marotta, Vinod Singh
{"title":"PROBIOTICS - A PROBABLE THERAPEUTIC AGENT FOR SPONDYLOARTHROPATHY.","authors":"Nandini Singh, Hariom Yadav, Francesco Marotta, Vinod Singh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Spondyloarthropathy (SpA) or spondyloarthrosis refers to any joint disease of the vertebral column. Among the entities of SpA, ankylosing spondylitis has drawn the attention of some researchers, because of its specific mechanism of disease progression. It has been studied earlier that its progression is due to the presence of HLA (human leukocyte antigen) - B27. It shows molecular similarity and immunological cross-reactivity with some of the gut microbiome. Since SpA could be treated or its symptoms could be lessen by medications, but medications itself show many side effects and other complications. Probiotic- being the natural product has been found to be effective against many SpA entities, including Ankylosing Spondylitis. It alters gut microflora somehow in such a way that it helps in reducing the predisposition of any factor to SpA. Here we consider the complex relationship between SpA pathogenesis and gut microbes; with discussion that how use of probiotics as an alternative drug therapy may treat or reduce the progression of SpA, which could be a better future target to treat SpA entities.</p>","PeriodicalId":53704,"journal":{"name":"International Journal of Probiotics and Prebiotics","volume":"12 2","pages":"57-68"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474668/pdf/nihms-991537.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37347897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PROBIOTIC APPROACHES FOR TARGETING INFLAMMATORY BOWEL DISEASE: AN UPDATE ON ADVANCES AND OPPORTUNITIES IN MANAGING THE DISEASE. 针对炎症性肠病的益生菌方法:疾病管理的最新进展和机遇。
Manoj Kumar, Rajkumar Hemalatha, Ravinder Nagpal, Birbal Singh, Devraj Parasannanavar, Vinod Verma, Ashok Kumar, Francesco Marotta, Roberto Catanzaro, Biagio Cuffari, Shalini Jain, Laura Bissi, Hariom Yadav
{"title":"PROBIOTIC APPROACHES FOR TARGETING INFLAMMATORY BOWEL DISEASE: AN UPDATE ON ADVANCES AND OPPORTUNITIES IN MANAGING THE DISEASE.","authors":"Manoj Kumar, Rajkumar Hemalatha, Ravinder Nagpal, Birbal Singh, Devraj Parasannanavar, Vinod Verma, Ashok Kumar, Francesco Marotta, Roberto Catanzaro, Biagio Cuffari, Shalini Jain, Laura Bissi, Hariom Yadav","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Various commensal enteric and pathogenic bacteria may be involved in the pathogenesis of inflammatory bowel diseases (IBDs), a chronic condition with a pathogenic background that involves both immunogenetic and environmental factors. IBDs comprising of Crohn's disease, and ulcerative colitis, and pauchitis are chronic inflammatory conditions, and known for causing disturbed homeostatic balance among the intestinal immune compartment, gut epithelium and microbiome. An increasing trend of IBDs in incidence, prevalence, and severity has been reported during recent years. Probiotic strains have been reported to manage the IBDs and related pathologies, and hence are current hot topics of research for their potential to manage metabolic diseases as well as various immunopathologies. However, the probiotics industry will need to undergo a transformation, with increased focus on stringent manufacturing guidelines and high-quality clinical trials. This article reviews the present state of art of role of probiotic bacteria in reducing inflammation and strengthening the host immune system with reference to the management of IBDs. We infer that t healthcare will move beyond its prevailing focus on human physiology, and embrace the superorganism as a paradigm to understand and ameliorate IBDs.</p>","PeriodicalId":53704,"journal":{"name":"International Journal of Probiotics and Prebiotics","volume":"11 3-4","pages":"99-116"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NATURAL ANTIMICROBIALS AND THEIR ROLE IN VAGINAL HEALTH: A SHORT REVIEW. 天然抗菌剂及其在阴道健康中的作用:简要综述。
S E Dover, A A Aroutcheva, S Faro, M L Chikindas
{"title":"NATURAL ANTIMICROBIALS AND THEIR ROLE IN VAGINAL HEALTH: A SHORT REVIEW.","authors":"S E Dover, A A Aroutcheva, S Faro, M L Chikindas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lactobacillus species maintain the vaginal ecosystem in a healthy condition by production of antimicrobial substances. Depletion of lactobacilli in the vagina results in bacterial vaginosis (BV), where the normal flora is replaced by several bacterial pathogens, usually Gardnerella vaginalis and obligate anaerobes. BV may cause complications such as premature labor, low birth weight and increased risk of HIV acquisition. The currently recommended antibiotic treatments for BV are not always effective and often lead to reoccurrence of the infection. In many cases, this is due to the antibiotic-resistant forms of the pathogens. Therefore, there is an interest in the development of treatments using antimicrobials derived primarily from Lactobacillus spp., such as ribosomally produced antimicrobial peptides (bacteriocins) and lactic acid. These substances effectively inhibit pathogenic bacteria, are safe and do not pose any threat to healthy vaginal Lactobacillus spp. It may be possible to find an effective treatment against BV while reducing the infection's reoccurrence and the treatment-related complications through hurdle technology. This would be achieved by combining antimicrobials produced by Lactobacillus spp. with different natural antimicrobials obtained from plants or other non-pathogenic organisms.</p>","PeriodicalId":53704,"journal":{"name":"International Journal of Probiotics and Prebiotics","volume":"3 4","pages":"219-230"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908489/pdf/nihms88202.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29143229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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