Libri Oncologici最新文献_第2页

Gender equality in leading cancer centers 领先癌症中心的性别平等

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.09

Dragan Marinić Korolija, I. Kirac, L. Mayer, S. Varga

引用次数: 0

The role of metallothionein in breast cancer 金属硫蛋白在癌症中的作用

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.16

Sara Bilić-Knežević, Mirisa Tokić, T. Gulic, M. Avirović, D. Grebić

引用次数: 0

Fertility preservation in patients with gynecological cancer - is it possible? 妇科癌症患者的生育能力保存——有可能吗？

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.20

Z. Rendić-Miočević, M. Alvir, I. Orešković, L. Beketić-Orešković

{"title":"Fertility preservation in patients with gynecological cancer - is it possible?","authors":"Z. Rendić-Miočević, M. Alvir, I. Orešković, L. Beketić-Orešković","doi":"10.20471/lo.2022.50.02-03.20","DOIUrl":"https://doi.org/10.20471/lo.2022.50.02-03.20","url":null,"abstract":"The aim of this review article is to present current options for fertility preservation in young women with gynecological tumors (ovarian, endometrial or cervical cancer). An early pretreatment referral to multidisciplinary team which consists of general gynecologists, gynecologic oncologists, embryologists, radiologists, pathologists, and reproductive endocrinologists should be suggested to young women with gynecologic cancer, concerning the risks and benefits of fertility preservation options. Only a small percentage of patients with ovarian cancer and borderline ovarian tumors, are appropriate candidates for fertility preservation (FIGO stage IA and IC epithelial ovarian cancer). Following oophorectomy, ovarian tissue or oocytes are removed from the ovary for the use of cryopreservation; after completion of oncological treatment patient undergoes orthotopic retransplantation of ovarian tissue whereas oocytes may be used for in vitro fertilization. Live birth rates up to 53.8% have been reported after fertility preservation treatment in selected patients. In patients with endometrial cancer fertility preservation treatment means conserving of the uterus. Appropriate candidates for fertility preservation are younger women with well differentiated endometrial cancer, which does not invade the myometrium. Fertility preservation treatment in endometrial cancer is hormonal, based on progestins. After completion of fertility preservation treatment, frequent follow-ups are necessary, with tissue sampling (via curettage or endometrial biopsy) remaining standard approach in follow- up. Live birth rates after progestin therapy are around 60%, or even higher with the help of assisted reproductive procedures. In cervical cancer, fertility preservation treatment can be considered in women with early-stage disease (FIGO IA1, IA2, or IB1). Cone biopsy or conization followed by laparoscopic lymphadenectomy has been described as an appropriate procedure, with conception rates up to 47%.","PeriodicalId":53700,"journal":{"name":"Libri Oncologici","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48461395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of life in relation to social support and body image in women with breast cancer after mastectomy 癌症乳腺癌患者乳房切除术后生活质量与社会支持和身体形象的关系

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.14

G. Vuletić

{"title":"Quality of life in relation to social support and body image in women with breast cancer after mastectomy","authors":"G. Vuletić","doi":"10.20471/lo.2022.50.02-03.14","DOIUrl":"https://doi.org/10.20471/lo.2022.50.02-03.14","url":null,"abstract":"For many years, cancer have been the 2nd leading cause of death, both men and women, in Croatia, and breast cancer is among first three cause of death from cancer in women. Disease, especially cancer, has negative and multidimensional impact on quality of life. The aim of this research was to examine the relation between perceived social support and body image with quality of life in women with breast cancer who undergone surgical treatment mastectomy. Results showed that quality of life after the mastectomy in women with breast cancer was 53.58 %SM which was below the normative range, and indicating decreased QoL. Social support proves to be strongest protective factor for the quality of life in women with breast cancer who undergone mastectomy, and longer time from diagnosis was also associated with higher quality of life. Neither women’s age, level of body image disturbance nor type of additional treatment were shown to be significant predictors of the overall QoL Assessment of quality of life and perceived social support could become a valuable indicator of the success of multidisciplinary treatment and indicate areas where the woman needs additional help and support in order to achieve better quality of life.","PeriodicalId":53700,"journal":{"name":"Libri Oncologici","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46565159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lack of information on colorectal cancer in general public might be the reason for low response rates to screening progam 公众缺乏关于结直肠癌癌症的信息可能是筛查方案反应率低的原因

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.11

M. Bebek, S. Langer, Lana Botak, Petar Jazbec, V. Ramljak, I. Milas

引用次数: 0

HER2-low advanced breast cancer treatment HER2-低晚期癌症治疗

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.18

Marija Ban, E. Vrdoljak

引用次数: 0

Local treatment of breast cancer brain metastases 乳腺癌症脑转移的局部治疗

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.19

Ana Magličić, P. Podolski, Nera Šarić, M. Soče, M. Baučić, Sanja Vušković, Tena Mlinarić-Koprivanac, Dora Šimović, Petra Đelalija, I. Zrilić, M. Bašić-Koretić

引用次数: 0

Resonance imaging on the surgical management of newly diagnosed breast cancer 共振成像在新诊断乳腺癌症手术治疗中的应用

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.17

D. Grebić, P. Valković-Zujić, Iva Pozderac, Domagoj Kustić, Matea Hrboka-Zekić

{"title":"Resonance imaging on the surgical management of newly diagnosed breast cancer","authors":"D. Grebić, P. Valković-Zujić, Iva Pozderac, Domagoj Kustić, Matea Hrboka-Zekić","doi":"10.20471/lo.2022.50.02-03.17","DOIUrl":"https://doi.org/10.20471/lo.2022.50.02-03.17","url":null,"abstract":"Introduction: Breast cancer is the most commonly diagnosed malignancy in women and the leading cause of cancer death in women. Tumor size is a critical factor in determining the type and extent of surgical and oncologic treatment. It is accurately determined by imaging modalities such as mammography, ultrasound, and magnetic resonance imaging (MRI), which provide a more reliable determination of tumor size. The aim of our study was to investigate the impact of preoperative breast magnetic resonance imaging on surgical treatment of newly diagnosed breast cancer. Material and Methods: The study retrospectively reviewed the records of 241 participants with newly diagnosed breast cancer who underwent preoperative mammography, breast ultrasound, and MRI between 2016 and 2020 at University Hospital Centre Rijeka. Patients were diagnosed with invasive ductal carcinoma, invasive lobular carcinoma, ductal carcinoma in situ, or a combination of the types. Surgical treatment included one of the following procedures: simple quadrantectomy, quadrantectomy and sentinel lymph node biopsy, quadrantectomy and axillary lymph node dissection, mastectomy and sentinel biopsy, or mastectomy and axillary dissection. Results: Compared with histopathologic tumor size, breast MRI overestimated size in 10% of patients. T stage was underestimated in 5% of patients (p>0.050). In comparison, breast ultrasound overestimated tumor size in 12% and underestimated it in 48% (p<0.001). Similarly, mammography overestimated tumor size in 14% and underestimated it in 62% (p<0.001). Conclusion: In patients with newly diagnosed breast cancer, the use of preoperative breast MRI as an adjunct to mammography and ultrasound for locoregional staging significantly alters subsequent surgical treatment.","PeriodicalId":53700,"journal":{"name":"Libri Oncologici","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42543517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogen bonds energy distribution and information-theoretic analysis of blood serum from hamsters with experimental Graffi tumor 实验性Graffi肿瘤仓鼠血清氢键能分布及信息理论分析

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.10

N. Neshev, I. Ignatov, R. Toshkova, Cristos Drossinakis, G. Gluhchev

{"title":"Hydrogen bonds energy distribution and information-theoretic analysis of blood serum from hamsters with experimental Graffi tumor","authors":"N. Neshev, I. Ignatov, R. Toshkova, Cristos Drossinakis, G. Gluhchev","doi":"10.20471/lo.2022.50.02-03.10","DOIUrl":"https://doi.org/10.20471/lo.2022.50.02-03.10","url":null,"abstract":"The aim of the present study was to estimate the feasibility of blood serum hydrogen bonds energy distribution, and information-theoretic characteristics, as diagnostic markers for tumor disease in Graffi tumor bearing hamsters. Golden Syrian hamsters were randomly divided into two groups: a healthy control and an experimental one, challenged with Graffi tumor cells. The distributions of hydrogen bonds energies (-E) in the blood serum samples were investigated with a nonequilibrium process of droplets evaporation and sequential measurements of their wetting angle (Non-equilibrium Energy Spectrum (NES)). The measurements show significantly lower average hydrogen bond energy of the experimental samples than the controls. Shifts in NES toward depletion of (-E) at energy levels 0.0937, 0.1187, 0.1212, 0.1337, and 0.1387 eV, and an additional population at 0.0987, 0.1012, 0.1137, and 0.1237 eV energy levels were observed in the experimental samples compared to the controls. Such a pattern points to the possibility of utilizing the f(E) shifts at these energy levels as diagnostic markers of Graffi tumor in hamsters. Information-theoretic measures of Shannon entropy, Variation of information and Transformational information entropy were used to investigate possible differences between the experimental and control spectrum. Although they differ significantly in definitions, a comparison with the three information-theoretic measures did not reveal a statistically significant difference.","PeriodicalId":53700,"journal":{"name":"Libri Oncologici","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41478495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful pregnancy in women with endometrial carcinoma 子宫内膜癌患者的成功妊娠

Libri Oncologici Pub Date : 2022-12-22 DOI: 10.20471/lo.2022.50.02-03.21

Sandra Radović-Radovčić, Egon Kruezi, Jasna Martinčević, Lana Postružin-Gršić, Kristina Čimić

{"title":"Successful pregnancy in women with endometrial carcinoma","authors":"Sandra Radović-Radovčić, Egon Kruezi, Jasna Martinčević, Lana Postružin-Gršić, Kristina Čimić","doi":"10.20471/lo.2022.50.02-03.21","DOIUrl":"https://doi.org/10.20471/lo.2022.50.02-03.21","url":null,"abstract":"Endometrial cancer is the sixth most common cancer in women worldwide and fourth in Europe. Global estimates show rising incidence in both developed and developing countries. Standard surgical treatment leads to permanent loss of fertility. With current trends of reproductive-age women delaying childbearing, rising endometrial carcinoma incidence rates and a growing epidemic of obesity, research on conservative treatment remains a priority. Fertility-sparing treatment involves the use of oral progestins and levonorgestrel-releasing intrauterine devices, both shown to be beneficial and safe in early-stage endometrial carcinoma. We present a case of a 40-year-old female with endometrial adenocarcinoma grade 1 diagnosed during infertility workup. After one year of levonorgestrel-releasing intrauterine devices and almost three years after initial diagnosis was made, pregnancy was achieved. Term elective C-section delivery was done and a healthy infant was born. Today, a 46-yearold female, with six years of disease-free survival, still opts for conservative treatment. Aim of this paper is to show how conservative management with steady follow up in highly motivated individuals could be a reliable option for females of reproductive age with endometrial malignancies. Concept of fertility-sparing treatment should give hope to patients with malignant disease and unfulfilled reproductive goals.","PeriodicalId":53700,"journal":{"name":"Libri Oncologici","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42859238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0