Osteopathic Family Physician最新文献_第7页

Substance-Induced Psychosis in the Geriatric Population: Overview on Screening and Treatment 老年人群中物质诱发的精神病:筛查和治疗综述

Osteopathic Family Physician Pub Date : 2021-07-01 DOI: 10.33181/13045

Chloe Yeung, Joshua Raven, Abdul Brula

引用次数: 0

Ingrown Toenail Management Ingown Toenail Management

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13035

Oms-Iv Asma Ghafoor, Hamza Paracha, Dovrat Goldstein

引用次数: 1

The Rule of Three 三的法则

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13031

DO David Abend

引用次数: 0

Physician Beliefs Concerning Structural and Institutional Racism in Health Care 医生对医疗保健中结构性和制度性种族主义的看法

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13032

DO William Ciurylo, Carol A. Brenner, D. Thieme

引用次数: 0

The Osteopathic Approach to Treating Depression in Children and Adolescents 整骨疗法治疗儿童和青少年抑郁症

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13033

Oms-Iii Ravi Chinsky, Domin Chan

引用次数: 0

New-Onset Diabetic Ketoacidosis Secondary to Nivolumab Therapy in a Patient with Primary Central Nervous System Lymphoma Nivolumab治疗原发性中枢神经系统淋巴瘤继发的新发糖尿病酮症酸中毒

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13037

Do Pgy Christine Feng, DO Pavel Kibrik, C. Castañeda, Face Gurdeep Singh

{"title":"New-Onset Diabetic Ketoacidosis Secondary to Nivolumab Therapy in a Patient with Primary Central Nervous System Lymphoma","authors":"Do Pgy Christine Feng, DO Pavel Kibrik, C. Castañeda, Face Gurdeep Singh","doi":"10.33181/13037","DOIUrl":"https://doi.org/10.33181/13037","url":null,"abstract":"Introduction: Inhibitors of programmed cell death receptor (PD-1) and its ligand (PD-L1), such as nivolumab and pembrolizumab, confer anti-autoimmune activities and are therefore approved for anti-cancer therapy. Their mode of action removes autoimmunity checkpoints, thus increasing the risk of immune-related adverse events. \u0000Case Presentation: This report describes a clinical case of life-threatening diabetic ketoacidosis (DKA) in a patient after long-term nivolumab administration to treat primary central nervous system lymphoma (PCNSL). The patient presented to the emergency department (ED) with symptoms of fatigue, along with nausea and vomiting for two days; laboratory testing revealed significant hyperglycemia (glucose 673 mg/dL), elevated anion gap (>27), metabolic acidosis, ketonemia, glucosuria and ketonuria, findings of which were consistent with DKA. Given no personal history of diabetes mellitus or other autoimmune conditions and additional tests ruling out alternative causes, the patient was suspected of having newly-onset DKA secondary to nivolumab treatment. \u0000Management & Outcome: The patient was treated with fluids, electrolytes replenishments and insulin drip, which closed the anion gap and normalized electrolytes. She was transitioned to subcutaneous insulin. The patient recovered well and was discharged on Metformin and longacting insulin, with close follow-up with endocrinology and oncology. \u0000Discussion: Autoimmune endocrinopathies induced by checkpoint inhibitors for cancer treatment have been reported in the past. Newly-onset hyperglycemia and DKA are common autoimmunemediated side effects of checkpoint inhibitor uses in patients without prior history of diabetes mellitus. Clinicians should be aware to prevent this potentially life-threatening condition.","PeriodicalId":53642,"journal":{"name":"Osteopathic Family Physician","volume":"13 1","pages":"40-43"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42114612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Facial Rash with Eye Swelling 面部皮疹伴眼睛肿胀

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13038

Do Mba Facoep Lindsay Tjiattas-Saleski, Oms-Iii Erik Krueger

引用次数: 0

What the Past Has Taught Us: Best Practices for OFPs to Manage Stress During a Virus Outbreak 过去教会了我们什么：OFP在病毒爆发期间管理压力的最佳实践

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13034

Do Mms Tina Chuong, Do Mph Karen Lazarus, DO Meera Shah

引用次数: 0

Multisystem Inflammatory Syndrome in Infant with Negative SARS-CoV-2 RT-PCR and Antibodies 严重急性呼吸系统综合征冠状病毒2型RT-PCR和抗体阴性婴儿的多系统炎症综合征

Osteopathic Family Physician Pub Date : 2021-05-01 DOI: 10.33181/13036

Md Faap Facop Hanna S. Sahhar, DO Karly Derwitz, DO Erica Rubin

{"title":"Multisystem Inflammatory Syndrome in Infant with Negative SARS-CoV-2 RT-PCR and Antibodies","authors":"Md Faap Facop Hanna S. Sahhar, DO Karly Derwitz, DO Erica Rubin","doi":"10.33181/13036","DOIUrl":"https://doi.org/10.33181/13036","url":null,"abstract":"Since the declaration of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in March 2020 by the World Health Organization (WHO), there has been an emergence of a new syndrome termed multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. MIS-C is defined by the presence of fever, systemic inflammation and multiorgan dysfunction in association with SARS-CoV-2 infection or COVID-19 exposure. Knowledge of this syndrome’s presentation and pathophysiology is constantly evolving as more cases are reported in the literature. This case identifies a 3-month-old patient who tested negative for SARS-CoV-2 antigen, reverse transcriptase polymerase chain reaction (RT-PCR) and antibodies but qualified for MIS-C diagnosis. To the best of our knowledge and through extensive research at the time of diagnosing and reporting this condition to the healthcare authorities, we report the youngest pediatric patient with MIS-C diagnosis. We document this case to contribute to further understanding the variable manifestations of MIS-C and the importance of early diagnosis and treatment with intravenous immunoglobulin (IVIG).","PeriodicalId":53642,"journal":{"name":"Osteopathic Family Physician","volume":"13 1","pages":"35-39"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49035823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Cause of Dyspnea 呼吸困难的罕见原因

Osteopathic Family Physician Pub Date : 2021-03-01 DOI: 10.33181/13026

Vinesha Patel Do, David Do

引用次数: 0