Journal of Clinical and Aesthetic Dermatology最新文献

Refractory Acrodermatitis Continua of Hallopeau in a Pediatric Patient: Unveiling Underlying Mixed Connective Tissue Disorder. 顽固性持续肢端皮炎在儿科患者：揭示潜在的混合结缔组织疾病。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Nadine A Del Rosario, Shayla H U Nguyen, Ethan Q H Nguyen

{"title":"Refractory Acrodermatitis Continua of Hallopeau in a Pediatric Patient: Unveiling Underlying Mixed Connective Tissue Disorder.","authors":"Nadine A Del Rosario, Shayla H U Nguyen, Ethan Q H Nguyen","doi":"","DOIUrl":"","url":null,"abstract":"Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant that presents as sterile pustules on the hands and feet with a relapsing course. This condition is not easily treated, but literature shows some cases are successfully controlled with biologics such as etanercept, adalimumab, secukinumab, and ustekinumab. Mixed connective tissue disease (MCTD) is a type of autoimmune disease and is rarely seen in the pediatric population. It is characterized by overlapping features of various autoimmune disorders, often involving scleroderma, systemic lupus erythematosus, polymyositis, and other organ dysfunction. MCTD is typically diagnosed with lab testing to indicate the presence of specific autoantibodies to a nuclear matrix protein, such as ribonucleoprotein. This communication emphasizes the importance of revisiting diagnoses in patients with persistent, refractory skin conditions and highlights the need for comprehensive evaluation in the presence of evolving or atypical presentations, especially when autoimmune diseases are suspected. Steps for diagnostic workup and treatment may provide clinical benefits to patients and serve as a reference for other clinicians. The course of treatment for ACH and MCTD in the pediatric and adolescent population is discussed.","PeriodicalId":53616,"journal":{"name":"Journal of Clinical and Aesthetic Dermatology","volume":"18 6","pages":"22-25"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Current State of Patient Adherence to Lab Monitoring Guidelines for Janus Kinase Inhibitors in Patients with Alopecia Areata. 斑秃患者对Janus激酶抑制剂实验室监测指南的依从性现状。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Sujeeth Krishna Shanmugam, Victoria Palmer, Amy McMichael

{"title":"The Current State of Patient Adherence to Lab Monitoring Guidelines for Janus Kinase Inhibitors in Patients with Alopecia Areata.","authors":"Sujeeth Krishna Shanmugam, Victoria Palmer, Amy McMichael","doi":"","DOIUrl":"","url":null,"abstract":"Background: While Janus kinase inhibitors (JAKi) show excellent outcomes in Phase2b/3 trials for alopecia areata (AA), they do have potential side effects due to their immunosuppressive nature and other effects on the JAK-STAT pathway. These side effects can be mitigated by adherence to lab monitoring.Objective: The authors sought to analyze patients, using JAKi, to manage symptoms of AA, to determine frequency of lab monitoring and check for adherence to the recommended rate of every three months.Methods: A retrospective chart review was conducted by first identifying all patients diagnosed with AA at a specialty hair clinic in an academic dermatology department between January 2021 and May 2024. Each patient chart was reviewed for past and current use of any known oral JAKi. Fifty-seven patients were identified to meet our inclusion criteria and all of their charts were reviewed. The primary outcome is the average time between lab monitoring dates for each patient. The hypothesis was formulated after the data collection in the form of whether patients were being adherent to lab monitoring protocol.Results: Most patients were non-adherent to the lab testing frequency standard. Significant differences were found in blood test times between adherent and non-adherent patients and between non-adherent and extremely non-adherent patients with p-values less than 0.01 for both sets.Conclusion: Patients with AA undergoing JAKi treatment are not adhering to the recommended lab monitoring frequency. New tactics to improve adherence need to be taken.","PeriodicalId":53616,"journal":{"name":"Journal of Clinical and Aesthetic Dermatology","volume":"18 6","pages":"26-28"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic Cryotherapy: A Potential Therapeutic Option for Mild to Moderate Atopic Dermatitis. 全身冷冻疗法：轻度至中度特应性皮炎的潜在治疗选择。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Aileen Park, Leo Wan, Peter Lio

引用次数: 0

Physician and Trainee Beliefs and Comfort Regarding Psychodermatology Management: A Cross-sectional Survey From a Large Tertiary Care Center Faculty. 医生和实习生对精神皮肤病管理的信念和安慰：一项来自大型三级护理中心教员的横断面调查。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Annika M Hansen, Rachel Seifert, Abram Beshay, Zachary Hopkins, Aaron Secrest

{"title":"Physician and Trainee Beliefs and Comfort Regarding Psychodermatology Management: A Cross-sectional Survey From a Large Tertiary Care Center Faculty.","authors":"Annika M Hansen, Rachel Seifert, Abram Beshay, Zachary Hopkins, Aaron Secrest","doi":"","DOIUrl":"","url":null,"abstract":"Background: Both primary and secondary psychodermatoses are prevalent and dermatologists can play a pivotal role in their managment. We sought to understand dermatologists' training, comfort, and concerns for prescribing psychotropic medication for these condtions.Methods: We surveyed 49 dermatologists at the University of Utah, querying demographic variables, training enviroment, exposure to psychotropic medication use in training, current prescribing comfort, and current prescribing patterns. Associations between questionnaire responses and dermatologist demographics and training patterns were evaluated using ordinal logistic regression.Results: Across the 42 collected surveys, most had limited exposure to psychotropic medication and psychodermtoses managment in residency, most were encouraged to refer these patients to psychiatry, and lack of training on use and side effects were the most commonly cited reasons for not prescribing psychotropic medications. Having more faculty who advocated for psychtropic medication use and training during residency on psychodermatoses were associated with greater prescribing comfort (OR=6.77, 1.54-29.8 and OR=6.09, 1.80-20.6 respectively).Conclusion: Most dermatologists surveyed had limited exposure and training using psychotrophic medications for psychodermatoses. Lack of training and experience with these medications was a significant factor affecting prescribing comfort, highlighting the improtance of expanded residency training on the use of psychotrophic medications and the managent of primary and secondary dermatoses.","PeriodicalId":53616,"journal":{"name":"Journal of Clinical and Aesthetic Dermatology","volume":"18 6","pages":"10-13"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Efficacy of Complementary and Alternative Medicines Utilized In Cosmetic and Surgical Dermatology: A Comprehensive Review. 美容和外科皮肤病学中使用的补充和替代药物的疗效：综合综述。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Promise Ufomadu, Bartley Joseph Gill, Theodore Rosen, Ikue Shmizu, Ida Orengo

{"title":"The Efficacy of Complementary and Alternative Medicines Utilized In Cosmetic and Surgical Dermatology: A Comprehensive Review.","authors":"Promise Ufomadu, Bartley Joseph Gill, Theodore Rosen, Ikue Shmizu, Ida Orengo","doi":"","DOIUrl":"","url":null,"abstract":"Background: Lately, there has been a growing demand for the utilization of complementary and alternative medicines (CAMs) with dermatological applications. This is true despite limited RCT-level studies on such agents. This presents a barrier for dermatologists and fellow clinicians in counseling patients who may be using or are tempted to use these CAM modalities. This review highlights CAM agents used by patients for applications in cosmetic and surgical dermatology, exploring their efficacy and toxicity profiles.Methods: A comprehensive review was conducted on the effectiveness of several CAMs utilized in cosmetic and surgical dermatology by patients. A literature search was performed using PubMed, Embase, Google Scholar, Web of Science, and Cochrane.Results: Most CAM agents studied had statistically insignificant results, and for CAM agents that had significant results in efficacy, the studies were questionable due to flawed randomization, lack of proper blinding, faulty data analysis, poor study design, suggestion of bias, small sample size, and limited clinical application.Conclusion: CAM agents have promising potential in dermatologic use; however, more RCT-level studies are needed. A study design that either emphasizes a comparison between the CAM agent and conventional therapy, or the CAM agent with or without conventional therapy should be incorporated in future studies. As of now, dermatologists should be cognizant of bias in published studies demonstrating the effectiveness of certain CAM agents, as well as the possible adverse effects.","PeriodicalId":53616,"journal":{"name":"Journal of Clinical and Aesthetic Dermatology","volume":"18 6","pages":"29-40"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Established and Emerging Laser Treatments for Acne Vulgaris in Diverse Skin Types. 建立和新兴的激光治疗痤疮寻常在不同皮肤类型。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Kimberly Huerth, Chiamaka Ohanenye, Andrea Quartey, Brooke Jackson, Valerie Callender

{"title":"Established and Emerging Laser Treatments for Acne Vulgaris in Diverse Skin Types.","authors":"Kimberly Huerth, Chiamaka Ohanenye, Andrea Quartey, Brooke Jackson, Valerie Callender","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This review examined studies published during the past two decades in which lasers were used to treat acne vulgaris. Its aim was to assess the mechanism, efficacy, and safety of lasers as a treatment modality for this vexingly common and potentially disfiguring condition.Methods: PubMed searches were performed to identify articles published through December 2023 that discuss the use of lasers for the treatment of acne vulgaris.Results: Various lasers, including visible light, infrared, fractional ablative CO₂ lasers with isotretinoin, and two 1726-nm lasers approved by the United States Food and Drug Administration, show efficacy in treating acne vulgaris. Studies vary widely in their design, characteristics, and methodological rigor.Limitations: The available literature on using lasers to treat acne is limited by variability in study design, short-term follow up, and small sample sizes.Conclusion: Lasers have demonstrated efficacy as primary or adjunctive treatment modalities for acne vulgaris in certain clinical scenarios. Larger randomized, controlled, double-blinded studies with sufficiently long follow-up periods and standardized objective measurements are needed to substantiate the efficacy of lasers in treating acne vulgaris.","PeriodicalId":53616,"journal":{"name":"Journal of Clinical and Aesthetic Dermatology","volume":"18 6","pages":"41-48"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multidisciplinary Dermatology: A Framework from the Association of Academic Cosmetic Dermatology. 多学科皮肤病学：学术美容皮肤病学协会的框架。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Alexandra Richmond, Lucia Ray, Kevin Truong-Balderas, Neelam Vashi, Travis Blalock, Maria Hordinsky, Arisa Ortiz, Kristen M Kelly, Elika Hoss, Melissa L Shive, Rawaa Almukhtar, Stephanie R Jackson Cullison, Bianca Y Kang, Yakir Levin, Saranya P Wyles, Murad Alam

引用次数: 0

The Colorimetric Scale for Skin of Color Should Replace the Fitzpatrick Skin Type Scale for Classifying Individuals with Darker Skin. 有色皮肤的色度量表应该取代菲茨帕特里克皮肤类型量表来对深色皮肤进行分类。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Philip R Cohen

引用次数: 0

Analysis of Reddit Reveals Risankizumab Questions Among Patients with Psoriasis. Reddit的分析揭示了牛皮癣患者对利桑单抗的质疑。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-06-01

Jennifer Wang, Paras Patel, Jessica Mineroff, Jared Jagdeo

{"title":"Analysis of Reddit Reveals Risankizumab Questions Among Patients with Psoriasis.","authors":"Jennifer Wang, Paras Patel, Jessica Mineroff, Jared Jagdeo","doi":"","DOIUrl":"","url":null,"abstract":"Objective: The rapid expansion of the internet, specifically social media, has reshaped how patients approach their health and obtain their medical information. Specifically, Reddit communities have become important spaces for patients with psoriasis to engage in discussions, particularly regarding the newly United States Food and Drug Administration-approved medication, risankizumab. The objective of this study was to analyze questions from patients with psoriasis about risankizumab on Reddit.Methods: The authors analyzed all risankizumab-related questions posted on the r/Psoriasis and r/Skyrizi subreddits. Questions were categorized and subcategorized for analysis.Results: A total of 222 questions from 181 posts were analyzed. The largest proportion of questions were regarding side effects (26.1%) and cost and insurance (14.9%). This analysis of risankizumab questions on Reddit reveals key insights into the informational needs of patients with psoriasis and demonstrates the value of utilizing online platforms to better understand patient concerns.Limitations: One limitation of this study is that Reddit users may not be representative of the overall psoriasis population.Conclusion: The study presents a distinct approach by harnessing the power of social media data to understand patient perspectives, which may not be readily apparent in clinical settings. This information may help physicians improve the overall patient experience and provide more tailored clinical care.","PeriodicalId":53616,"journal":{"name":"Journal of Clinical and Aesthetic Dermatology","volume":"18 6","pages":"14-17"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of Neoadjuvant PD-1 Inhibitors in the Setting of Cutaneous Malignancies. 新辅助PD-1抑制剂在皮肤恶性肿瘤中的应用综述。

Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-05-01

Ariel R Darnall, David Baltazar, Dathan Hamann, Nathalie Zeitouni, Justin Moser

{"title":"A Review of Neoadjuvant PD-1 Inhibitors in the Setting of Cutaneous Malignancies.","authors":"Ariel R Darnall, David Baltazar, Dathan Hamann, Nathalie Zeitouni, Justin Moser","doi":"","DOIUrl":"","url":null,"abstract":"Considering the rapid pace of developments in the field of cancer immunotherapy, continuous updates on the topic are critical for the medical community. With incidences of cutaneous malignancies on the rise, it is more imperative than ever to utilize and understand current and future treatment modalities. Currently, the United States (US) Food and Drug Administration (FDA) approval for various immune checkpoint inhibitors (ICIs), particularly programmed cell death protein 1 (PD-1) inhibitors, in an adjuvant setting for various cutaneous malignancies is the mainstay in treatment of a number of cutaneous malignancies. Given the transformative potential of PD-1 inhibitors within the realm of immunotherapy, an understanding of the current state of research in this area is essential for dermatologists. This is important because in the cutaneous oncological world, neoadjuvant therapy is quickly demonstrating to show significant importance skin cancer treatment. Traditional neoadjuvant therapy involves a combination of chemotherapy, radiation, and/or targeted therapy, depending on the type and stage of malignancy. The main objective in these therapies has been to reduce tumor size for improved operability, manage systemic disease, and treat operable tumors prior to surgical intervention to obtain a more favorable long-term survivability. This review aims to provide a succinct analysis of both recent and current research of PD-1 inhibitors in the neoadjuvant setting of melanoma, squamous cell carcinoma, and merkel cell carcinoma.","PeriodicalId":53616,"journal":{"name":"Journal of Clinical and Aesthetic Dermatology","volume":"18 5","pages":"30-35"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0