International Medical Journal Malaysia最新文献_第10页

Laboratory Diagnosis of Dengue: A Review 登革热的实验室诊断:综述

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V14I1.452

Shamala Ds

引用次数: 15

Resection of Thumb Metacarpal Ewing Sarcoma and Primary Reconstruction with Non-Vascularized Osteoarticular Metatarsal Autograft 拇指掌骨尤文氏肉瘤切除术及自体无血管化骨关节跖骨重建

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V14I1.465

Ariff Ms, Faisham Wi, J. Krishnan, W. Zulmi

引用次数: 1

Hartman’s solution or normal saline in the treatment of hyperemesis gravidarum among South East Asian population: a randomised controlled trial Hartman溶液或生理盐水治疗东南亚人群妊娠剧吐的随机对照试验

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V7I2.779

I. Adibah, D. Khursiah, Ahmad Ai, Zaki Nnm

{"title":"Hartman’s solution or normal saline in the treatment of hyperemesis gravidarum among South East Asian population: a randomised controlled trial","authors":"I. Adibah, D. Khursiah, Ahmad Ai, Zaki Nnm","doi":"10.31436/IMJM.V7I2.779","DOIUrl":"https://doi.org/10.31436/IMJM.V7I2.779","url":null,"abstract":"ABSTRACT Introduction: The aim of treatment for hyperemesis gravidarum is to stop vomiting, correction of dehydration, starvation and electrolytes imbalance. The common types of fluid used for fluid replacement are isotonic solutions like normal saline and hartman’s solutions. The absence of potassium in normal saline makes hartman’s solution superior but there is a possibility that the lactate component in hartman’s solution could worsen the starvation state of the patients. This study is to evaluate which of these two solutions is more effective for fluid replacement in hyperemesis gravidarum. The objectives are to compare which solution corrects dehydration, hypokalaemia and acetonuria faster and to evaluate whether the ketosis state is aggravated by lactate component in hartman’s solution. Materials and Methods: Patients with hyperemesis gravidarum were randomised to receive either Hartman;’s solution or normal saline at the rate of 125mls/hour. Blood urea and serum electrolytes, haematocrit, lactate and urine acetone were taken during admission and repeated every 12 hours. The volume of fluid required to correct dehydration, hypokalaemia and acetonuria were compared. Comparison of the pre and post treatment level of serum lactate were also done. Results: Both hartman’s solution and normal saline are both effective in correcting dehydration (11.52±3.28 pints versus 11.94 ± 2.30pints respectively) and acetonuria (11.64 ± 2.75 pints versus 11.64 ± 2.54 pints respectively). A lower volume of hartman’s solution was needed to correct hypokalaemia (8.34 ± 2.44 pints versus 8.88 ± 2.63 pints) but was not statistically significant. Ketonaemia was not made worse after treatment with hartman’s solution. Conclusion: Normal saline and hartman’s solution are equally effective in treating complications of hyperemesis gravidarum. KEYWORDS: Hyperemesis Gravidarum, Fluid Replacement, Dehydration, Hypokalaemia, Ketosis","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46112008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Intention to seek medical consultation for symptoms of upper respiratory tract infection- a cross-sectional survey 对上呼吸道感染症状求医意向的横断面调查

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V14I2.428

Chai-Eng Tan, A. H. M. Roozi, W. Wong, S. N. Sabaruddin, N. Ghani, Z. C. Man

{"title":"Intention to seek medical consultation for symptoms of upper respiratory tract infection- a cross-sectional survey","authors":"Chai-Eng Tan, A. H. M. Roozi, W. Wong, S. N. Sabaruddin, N. Ghani, Z. C. Man","doi":"10.31436/IMJM.V14I2.428","DOIUrl":"https://doi.org/10.31436/IMJM.V14I2.428","url":null,"abstract":"Introduction: The common cold is the commonest reason for primary care encounters worldwide. This paper aims to describe the reasons that influence patients to seek medical consultation for the common cold. Methods: This was a cross-sectional survey conducted among adult patients of an urban teaching primary care clinic. An adapted bilingual survey form was administered by the researchers to obtain data regarding their decision to seek medical consultation for a cold and the reasons for their decision. Quantitative analyses were done to describe the close-ended responses. Open-ended responses were analysed using a qualitative approach and the frequencies of the themes were reported. Results: A total of 320 respondents participated in this study, with a response rate of 91.4%. They were predominantly females (59.4%), Malay (70.9%), and had tertiary education (65.9%). More than half of the patients (52.5%) said they would seek consultation for cold symptoms. Fever was the commonest symptom (57-61%) which compelled them to seek consultation. The commonest reason for seeking consultation was to get medications (41.7%), whereas the commonest reason not to seek consultation was the practice of self-medication (44.2%). Ethnicity was found to be significantly associated with the decision to seek doctor’s consultation. Conclusion: Colds are usually self-limiting and do not result in complications. Empowering patients by providing appropriate self-care knowledge can help to reduce the burden of primary care services. Patients should be taught about red flag symptoms as well as drug safety for medications commonly taken for colds.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44746336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Quantification of anti-fertility compound-Diosgenin concentration in the fenugreek seeds aqueous extract (FSA) 胡芦巴种子水提物中抗生育化合物薯蓣皂苷元的含量测定

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V15I1.410

Ahmed Kaid N. Allaw, Norbaiyah Mb, Norazian Mh

{"title":"Quantification of anti-fertility compound-Diosgenin concentration in the fenugreek seeds aqueous extract (FSA)","authors":"Ahmed Kaid N. Allaw, Norbaiyah Mb, Norazian Mh","doi":"10.31436/IMJM.V15I1.410","DOIUrl":"https://doi.org/10.31436/IMJM.V15I1.410","url":null,"abstract":"Introduction: This study aims to build a standardization method for preparation of effective powder from FSA and to quantify diosgenin in FSA. Methodology: One kg of FS were used in this study. Setting: BMS, KOM and KOP, IIUM Kuantan campus. FS were washed with distilled water to exclude any foreign matter, and were then air dried. FS-powder were put in distilled water in a ratio of 1 g of powder in 20 ml of distilled water and were shaken at room temperature for 24 hours. Ten mg of hydrolyzed extract sample was diluted in 10 ml volumetric flask with methanol for 15 minutes. Chromatographic estimation was performed using an equilibrated reverse phase Eclipse XDB-C18 column (particle size 5 μg, 4.6 mm x 150 mm). Results: One gram of FSA extract was hydrolyzed to produce sapogenins and 46.6% was recovered. A calibration curve that was constructed based on five dilutions of diosgenin standard at concentrations of 2, 5, 10, 20, 30 and 50 ppm produced a linear graft (r = 0.999). The concentration of diosgenin in FSA extract as calculated using the regression analysis was found to be 29.66 μg/ml, 13.81 % w/w on dried weight basis. Conclusion: Preparation and standardization of effective powder from FSA are the corner stone of many scientific researches in IIUM and Malaysia. Diosgenin is available in the FSA in adequate concentration. The adequate amount of diosgenin in the FSA will guide us to do further study in the way of preparation of a natural product that can be used in the field of reversible anti-fertility therapy.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47240371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Male Contraceptive Behavior in Rajshahi District of Bangladesh 孟加拉国Rajshahi地区男性的避孕行为

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V7I2.778

Mosiur R, Rafiqul I, Matin A

{"title":"Male Contraceptive Behavior in Rajshahi District of Bangladesh","authors":"Mosiur R, Rafiqul I, Matin A","doi":"10.31436/IMJM.V7I2.778","DOIUrl":"https://doi.org/10.31436/IMJM.V7I2.778","url":null,"abstract":"ABSTRACT This article examines the actual scenario of male involvement either as a user of contraceptive methods or supportive reproductive partners of women on contraceptive use in Rajshahi district of Bangladesh. The analysis shows that, knowledge and use of contraception are low in our study area. Comparative figures of contraceptive practice between men and women found a large disparity. Findings reveal that the user rate of all male contraceptive methods (e.g., condom at 17 percent) is still low compared to that of female methods (pill at 33.8 percent), which shows that men like to impose contra ceptive responsibility on women. Identification of socio-economic and demographic differentials affecting contraceptive behavior of men is performed through the technique of logistic regression. This paper elucidates that education, residence, fertility preference, mass media facility and knowledge about AIDS are the significant factors to influence contraceptive practices among men. Regarding the factors shunning the contraceptive practice we found that men’s opposition to use contraceptive methods is as most significant. The next reason for not using is related to contraceptive method. KEY WORDS: Modern Method, Traditional Method, Fertility, AIDS/STDS","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41367647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Antioxidants and Lipid Peroxidation Status In Women with Breast Cancer 癌症妇女体内抗氧化剂与脂质过氧化状况

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V14I1.459

Seraj Ak, M. Shankhar, Raju Kd, J. Punam, P. Anju, Rajat Ka

{"title":"Antioxidants and Lipid Peroxidation Status In Women with Breast Cancer","authors":"Seraj Ak, M. Shankhar, Raju Kd, J. Punam, P. Anju, Rajat Ka","doi":"10.31436/IMJM.V14I1.459","DOIUrl":"https://doi.org/10.31436/IMJM.V14I1.459","url":null,"abstract":"Introduction: Breast cancer is one of the most common malignancy in women and is the leading cause of cancer related death worldwide. Reactive oxygen species (ROS) play an important role in the development of tumours. Several mechanisms leading to oxidative stress have been proposed in cancer patients. In this study we aimed to measure and compare the levels of zinc, superoxide dismutase, catalase, vitamin C, vitamin E, and malondialdehyde in breast cancer patients and age matched healthy controls. Methods: In this comparative cross sectional study, 30 confirmed breast cancer cases and 30 age and sex matched controls were enrolled after taking their consent. Blood sample was collected in EDTA vial, and the parameters of oxidative stress were evaluated by spectrophotometric and atomic absorption spectrophotometric methods. Results: Zinc and MDA level were significantly higher (p<0.001) in cases (106.4 µg/dl and 7.12 nmol/ml) compared to controls (89.8µg/ dl and 3.99nmol/ml). In contrast, there were lower catalase, vitamin C and E levels in cases (28.7±14.56, 0.92±0.35 and 0.68±0.13 mg/dl) compared to controls (37.1±14.7,1.62±0.59 and 1.02±0.22 mg/dl) and were statistically significant (p<0.05 and p<0.001). Whereas, superoxide dismutase was lower in cases compared to controls, but was not statistically significant. Conclusion: Zinc was found to be higher in our study as it is a pivotal element in all rapidly growing tissues. Enhanced lipid peroxidation observed in the circulation of breast cancer patients in our study can be attributed to over production of ROS and deficiency of antioxidant defences. Oxidative stress in cancer cells may trigger excessive consumption of antioxidants as a compensatory mechanism which lead to its lower concentration.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43539907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Assessing and exploring the competency of prehospital emergency medical service personnel in Klang Valley, Malaysia: a mixed method approach 马来西亚巴生谷院前急救人员能力评估与探索：一种混合方法

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V13I2.472

M. S. Nurumal, A. Sukonthasarn, S. Wangsrikhun, Chawapornpan Chanpransit

{"title":"Assessing and exploring the competency of prehospital emergency medical service personnel in Klang Valley, Malaysia: a mixed method approach","authors":"M. S. Nurumal, A. Sukonthasarn, S. Wangsrikhun, Chawapornpan Chanpransit","doi":"10.31436/IMJM.V13I2.472","DOIUrl":"https://doi.org/10.31436/IMJM.V13I2.472","url":null,"abstract":"The notion of competency in pre-hospital emergency medical service (EMS) personnel is mainly focused on the professional proficiency that he/she has to provide intervention outside of hospital setting. Consequently, the effectiveness of pre-hospital EMS performance very much depends upon the capability of the personnel at the scene and as well during transport to the definitive care center. The aim of this study is to appraise and explore the competency of pre-hospital care staff and provide strategies for improvement. Methods: A mixed method approach combining the qualitative and quantitative study design. Of 134 staffs only 111(82.84%) returned the questionnaire. Nine semi-structured interviews and two focus group discussions were performed. The main informants were nurses/assistant medical officers, nurse/assistant medical officer administrators, and emergency physicians. Results: From the quantitative finding on the competency of staff handling pre-hospital EMS, all had the essential knowledge and skills. However, most of them reported not having good knowledge and skills for invasive procedures (31%-61%), include giving medications (61%-66%). The qualitative information provided insight about the issues and strategies for the personnel in regards to competency. All the relevant qualitative data were merged into 5 categories relating issues and 5 categories to strategies that could affect the competency of the personnel. Conclusion: Pre-hospital EMS systems need to consider that the competency of pre-hospital EMS personnel has to come along with the responsible attitude of the staff itself, the support of medical direction, clear protocol for guiding them whenever needed, and continuous professional-development courses require them to maintain their professional proficiency.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49456658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Stress and Its Association with the Academic Performance of Undergraduate Fourth Year Medical Students at Universiti Kebangsaan Malaysia 压力及其与马来西亚Kebangsaan大学本科四年级医学生学业成绩的关系

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V13I1.488

Hasan NAb, Jin THb, Othman MNb

{"title":"Stress and Its Association with the Academic Performance of Undergraduate Fourth Year Medical Students at Universiti Kebangsaan Malaysia","authors":"Hasan NAb, Jin THb, Othman MNb","doi":"10.31436/IMJM.V13I1.488","DOIUrl":"https://doi.org/10.31436/IMJM.V13I1.488","url":null,"abstract":"ABSTRACT Introduction: Student can be stressed due to different stressors such as academic, financial, health related or loss of close family member or friend, etc. Stress is the bodies’ reaction both neurologically and physiologically to adapt to the new condition. Stress has a negative effect on the academic performance of the students. This study was aimed to explore the stress and stressors and also to determine the association between stress levels and the academic performances in terms of cumulative grade point average (CGPA) of undergraduate medical students. Methods: It was a cross-sectional study conducted among all 234 year-4 medical students of Universiti Kebangsaan Malaysia (UKM), session 2011-2012. Sample size comprised of 179 students after fulfilling all inclusion and exclusion criteria. A validated Medical Students’ Stressor Questionnaire (MSSQ) was used to collect the data. Stress level and its association with CGPA of semester-1 examination were analysed. Results: Response rate was 76.49%, where 72% were female and 69% resided in the hostel. Academic Related and Social-related Stressors caused for severe and high stress in 84% and 49% respondents respectively, with insignificant differences between gender and residency. Respondents with a high and severe stress level were observed to have higher CGPA. Conclusion: UKM medical students are highly resourceful to manage their stress well and thus denying the negative effect of stress towards their academic performance. Medical schools should train students exposing various personal and professional developmental activities that able to face the everyday challenges and manage stress well and thereby achieve better academic performance. KEYWORDS: Stress, stressor, well-management, academic performance","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44992401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 42

Operative internal fixation of isolated femoral diaphyseal fractures - is interlocking nail the best option? 孤立性股骨干骨折手术内固定-交锁钉是最佳选择吗?

International Medical Journal Malaysia Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V7I2.780

Zairul-Nizam Zf

引用次数: 0