Petr Mikhailovich Maslyukov, Valentina Vyacheslavovna Porseva, Polina Aleksandrovna Anfimova, Lidiya Georgievna Pankrasheva, Andrey Anatolyevich Baranov, Nikolay Yurievich Levshin, Konstantin Yurievich Moiseev
{"title":"Influences of intrahypothalamic administration of microrna inhibitors and mimetics on blood plasma biomarkers with aging of the rat","authors":"Petr Mikhailovich Maslyukov, Valentina Vyacheslavovna Porseva, Polina Aleksandrovna Anfimova, Lidiya Georgievna Pankrasheva, Andrey Anatolyevich Baranov, Nikolay Yurievich Levshin, Konstantin Yurievich Moiseev","doi":"10.14300/mnnc.2023.18068","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18068","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"2016 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135908486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Korobkeev, Evgeniya Alysheva, A. Khodzhayan, Oxana Lezhnina
{"title":"Аngioarchitectonics of the subepicardial vascular bed of the heart on the lateral surface of the left ventricle in young adulthood","authors":"A. Korobkeev, Evgeniya Alysheva, A. Khodzhayan, Oxana Lezhnina","doi":"10.14300/mnnc.2023.18039","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18039","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66996196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Yuryevna Ryabova, I. Kozlova, T. G. Shapovalova, Mikhailovna Shashina Marina, Anastasia Sergeevna Shiryaeva
{"title":"Features of cardiac remodeling in patients with frequent exacerbations of severe COPD and in its combination with arterial hypertension","authors":"Anna Yuryevna Ryabova, I. Kozlova, T. G. Shapovalova, Mikhailovna Shashina Marina, Anastasia Sergeevna Shiryaeva","doi":"10.14300/mnnc.2023.18002","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18002","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66994776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kade, P. P. Polyakov, S. A. Zanin, E. S. Zanina
{"title":"Modern ideas about the etiology and pathogenesis of hereditary hemorrhagic telangiectasia","authors":"A. Kade, P. P. Polyakov, S. A. Zanin, E. S. Zanina","doi":"10.14300/mnnc.2023.18021","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18021","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66995924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. N. Belokopytova, V. Baturin, I. Dolgova, S. Karpov
{"title":"Immunological predictors of cognitive impairment in patients with type 2 diabetes mellitus","authors":"M. N. Belokopytova, V. Baturin, I. Dolgova, S. Karpov","doi":"10.14300/mnnc.2023.18006","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18006","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66995391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Yagoda, P. Koroy, Elena Otarievna Demurcheva, Nikolay Evgenyevich Hvatalin, Anna Daniilovna Svetogurova, V. Sarithala
{"title":"Vitamin D as a marker of non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus","authors":"A. Yagoda, P. Koroy, Elena Otarievna Demurcheva, Nikolay Evgenyevich Hvatalin, Anna Daniilovna Svetogurova, V. Sarithala","doi":"10.14300/mnnc.2023.18028","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18028","url":null,"abstract":"Ninety patients with type 2 diabetes mellitus (DM) aged 39 to 76 years were examined. Women were 71 (78.9 %), men – 19 (21.1 %). The diagnosis of non-alcoholic fatty liver disease (NAFLD) was made based on an ultrasound examination of the abdominal cavity. The levels of vitamin D in the blood were determined by enzyme immunoassay. NAFLD was detected in 66.7 % of patients with type 2 DM. Vitamin D levels in the blood of patients with NAFLD on the background of type 2 DM were lower, and its deficiency was more common than in cases of DM without NAFLD. Serum vitamin D levels in patients with NAFLD and cholestatic syndrome were lower than in cases of NAFLD without signs of cholestasis. According to regression analysis, the development of NAFLD in type 2 DM is affected by reduced vitamin D levels in the blood and increased values of glucose, alanine aminotransferase, and low-density lipoproteins. Thus, the development of NAFLD against the background of type 2 DM is associated with a decrease in vitamin D concentration in the blood. Serum level of vitamin D less than 16.18 ng/ml can be used as a predictor of NAFLD in patients with type 2 DM.","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66996004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Petrosyan, N. Verisokina, L. Klimov, V. Kuryaninova, R. Atanesyan, O.S. Kirienko
{"title":"The significance of vitamin D in the regulation of bone metabolism in term and premature infants","authors":"M. Petrosyan, N. Verisokina, L. Klimov, V. Kuryaninova, R. Atanesyan, O.S. Kirienko","doi":"10.14300/mnnc.2023.18053","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18053","url":null,"abstract":"Improvements in neonatal care for premature babies have led to significant improvements in survival rates for low and very low birth weight infants. Due to the characteristics of calcium-phosphorus homeostasis and bone metabolism, neonatologists often encounter skeletal system pathology in premature newborns. This condition is a metabolic disease of premature infants’ bones based on a deficiency of calcium, phosphorus, and vitamin D, resulting in impaired growth and mineralization of the growing skeleton. Vitamin D is one of the most important regulators of bone metabolism. On the one hand, it stimulates the absorption of Ca2+ and P3-in the small intestine, and on the other hand, it has a direct effect on bone tissue cells (osteoblasts, osteocytes, osteoclasts, and chondrocytes) through the vitamin D receptors located in them. Risk factors for developing bone metabolism disorders in term and premature newborns, as well as the correlating role of vitamin D in skeletal formation and maintaining homeostasis, were considered.","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66996327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diverticulum of the right half of the colon. A case report","authors":"Andrey Sergeevich Gorbunov, Fedor Petrovich Vetshev, Sergey Petrovich Vetshev, Yulia Vladimirovna Lerner, Radmila Vladimirovna Karpova, Natalya Vasilievna Petukhova, Ksenia Sergeevna Ruskova, Daria Viktorovna Momatyuk","doi":"10.14300/mnnc.2023.18075","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18075","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135908488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Bobrysheva, S. Pisarenko, D. Kovalev, E. Eremenko, A. Ryazanova, Olga Viktorovna Semenova, D. V. Ulshina, A. Kulichenko
{"title":"Phylogenetic analysis of Bacillus anthracis strains isolated in the Republic of Dagestan","authors":"O. Bobrysheva, S. Pisarenko, D. Kovalev, E. Eremenko, A. Ryazanova, Olga Viktorovna Semenova, D. V. Ulshina, A. Kulichenko","doi":"10.14300/mnnc.2023.18007","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18007","url":null,"abstract":"genomic sequences from the international GenBank database were used. As a result of genetic analysis, it was found that the strains isolated in 1957 and 1963 belong to the main genetic line B, branch B.Br.002 and have a high degree of genetic relationship with strains from Western Siberia, which indicates their common origin. Isolates distinguished in 2019 belong to the TEA Br.008/011 group, A.Br.118 branch. These strains form a separate branch and are closely related to the «STI» clade. The data obtained can be used in the differentiation of strains during the investigation of outbreaks of anthrax.","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66995502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}