Radiology Case Reports最新文献

{"title":"Arteritic anterior ischemic optic neuropathy secondary to immune checkpoint inhibitors: A case report","authors":"Zahin Alam BS ,&nbsp;Tausif Ahmed Siddiqui BS ,&nbsp;Mohammed Usman Syed BS ,&nbsp;Pavan K. Kottamasu MD ,&nbsp;Tushar Nag ,&nbsp;Akm Rahman MD, DO","doi":"10.1016/j.radcr.2025.06.014","DOIUrl":"10.1016/j.radcr.2025.06.014","url":null,"abstract":"<div><div>Ischemic optic neuropathy (ION) occurs due to insufficient blood supply to the optic nerve, with anterior ischemic optic neuropathy (AION) commonly associated with giant cell arteritis (GCA). Immune checkpoint inhibitors (ICIs), used in cancer therapy, have been linked to neuro-ophthalmic immune-related adverse events (irAEs), though the development of arteritic anterior ischemic optic neuropathy (AAION) due to ICI therapy is exceptionally rare. This case report describes a 77-year-old male with metastatic renal cell carcinoma on ICI therapy who presented with bilateral vision loss and was diagnosed with AAION. MRI findings supported GCA-AAION with orbital involvement, and the patient showed immediate but partial improvement with corticosteroids, despite a nonconfirmatory temporal artery biopsy. This case underscores the need for heightened clinical awareness of ICI-associated ocular complications and highlights the challenges in diagnosing and managing ICI-induced AAION, emphasizing the need for further research into treatment strategies to mitigate irreversible vision loss.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4774-4777"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A diagnostic challenge: The unusual combination of Kommerell’s diverticulum and pulmonary sequestration due to type 1 congenital pulmonary airway malformation in a young patient","authors":"Andre-Alonso Taco-Masias MD ,&nbsp;Luz-Marina Pajares-Goicochea MD","doi":"10.1016/j.radcr.2025.05.109","DOIUrl":"10.1016/j.radcr.2025.05.109","url":null,"abstract":"<div><div>The simultaneous occurrence of Kommerell's diverticulum (KD), pulmonary sequestration (PS), and congenital pulmonary airway malformation type 1 (CPAM-1) represents an exceptionally rare clinical scenario. We present the first documented case of this triad in a young patient. We present a 14-year-old female with chronic cough and dysphagia underwent to thoracic CT and CT angiography revealing: 34 mm KD with aberrant left subclavian artery, Intralobar PS associated to CPAM-type1 features in the same pulmonary segment, mostly related to hybrid CPAM-sequestration lesion. This unique association suggests a shared embryological origin between vascular and pulmonary developmental anomalies. Imaging findings and multidisciplinary management are crucial given potential complications.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4785-4789"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of shoulder tuberculosis: Diagnostic challenges and insights","authors":"Oukassem Siham,&nbsp;Laasri Ihssane,&nbsp;Abourak Chaimae,&nbsp;Ennouili Hassan,&nbsp;El Fenni Jamal","doi":"10.1016/j.radcr.2025.05.076","DOIUrl":"10.1016/j.radcr.2025.05.076","url":null,"abstract":"<div><div>This case report presents a middle-aged male patient who presented with worsening left shoulder pain and restricted movement. Clinical examination revealed moderate restriction of shoulder motion. Laboratory tests showed elevated ESR and lymphocytosis. MRI of the shoulder revealed bony abnormalities, synovial thickening, and joint effusion. Histological examination revealed granulomatous inflammation with caseation, and although culture results were negative, Mycobacterium tuberculosis was confirmed by Myco-3 PCR. The patient was initiated on antitubercular therapy and showed a positive response. Extrapulmonary tuberculosis, especially musculoskeletal involvement, can be difficult to diagnose, but MRI plays a crucial role in detecting bone tuberculosis. A multidrug treatment regimen is essential for managing osteoarticular tuberculosis.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4790-4793"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gorlin-Goltz syndrome: Multidisciplinary approach for early diagnosis of rare disease for better patient outcome","authors":"Abdi Alemayehu MD ,&nbsp;Suleyman Fantahun MD ,&nbsp;Gelana Garoma DMD ,&nbsp;Matewos Amare DMD ,&nbsp;Firaol Birhanu BSc","doi":"10.1016/j.radcr.2025.06.012","DOIUrl":"10.1016/j.radcr.2025.06.012","url":null,"abstract":"<div><div>Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome (NBCCS), is an infrequent, autosomal dominant, multi-systemic disease characterized by odontogenic keratocysts (OKC) in the jaw, multiple basal cell carcinomas (BCC), ectopic calcifications of the falx and tentorium, and various other skeletal abnormalities. The syndrome can be recognized early in life during dental and dermatology visits or on routine radiographic studies, opening the door for further screening and follow-up of affected individuals and their offspring. We report a case of Gorlin syndrome diagnosed in a 37-year-old female patient with features of hypertelorism after presenting with jaw swelling of 6 months. The diagnosis was made after identifying multiple OKCs, bilamellar calcification of falx and tentorium, bifid spinous process, and bridging sella seen on head computed tomography (CT) scan, fulfilling the diagnostic criteria set for the syndrome. This case highlights the important role radiology has in diagnosing NBCCS and the importance of a multidisciplinary approach to provide a better prognosis for the patient.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4768-4773"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking measles in pregnancy: A fatal rare case of maternal measles with posthumous diagnosis in a resource-constrained setting","authors":"John Lugata ,&nbsp;Onesmo Mrosso ,&nbsp;Tecla Lyamuya ,&nbsp;Patricia Swai ,&nbsp;Rafiki Mjema ,&nbsp;Kajiru Kilonzo ,&nbsp;Bariki Mchome ,&nbsp;Nasra Batchu","doi":"10.1016/j.radcr.2025.06.039","DOIUrl":"10.1016/j.radcr.2025.06.039","url":null,"abstract":"<div><div>Measles, a highly contagious viral airborne disease, continues to loom as a public health concern worldwide. Despite the availability of an effective measles vaccine, maintaining a vaccine coverage of at least 95% is imperative to uphold herd immunity, which acts as a crucial barrier against the disease's resurgence. This safeguard against measles resurgence remains vulnerable, as outbreaks can occur in pockets of susceptible population where there is low vaccine uptake, even in regions that seemingly maintain satisfactory average vaccination coverage. We present a rare case from northern Tanzania of a 20-year-old female at 28 weeks of gestation age who presented with persistent cough with bloody sputum, chest pain, fevers, epistaxis, and episodes of bloody diarrhea. A postmortem examination was conducted and the findings revealed pathognomonic features of measles. Serum IgM was tested positive for measles result confirming the diagnosis. This rare case report of the pregnant woman with a posthumous diagnosis of measles emphasizes the ongoing complexities in diagnosing and managing measles. It highlights the necessity for an integrative diagnostic approach and heightened clinical awareness, particularly in resource-limited environments</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4749-4754"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental discovery of Tornwaldt’s cyst during evaluation for suspected obstructive sleep apnea syndrome in a patient with auditory symptoms","authors":"Saad Bouchlarhem ,&nbsp;Achraf Amine Sbai ,&nbsp;Drissia Benfadil ,&nbsp;Azeddine Lachkar ,&nbsp;Fahd El Ayoubi El Idrissi","doi":"10.1016/j.radcr.2025.06.006","DOIUrl":"10.1016/j.radcr.2025.06.006","url":null,"abstract":"<div><div>Tornwaldt’s cyst is a rare, congenital lesion of the nasopharynx due to incomplete regression of the notochordal-pharyngeal connection. It forms a midline cystic cavity in the pharyngeal bursa. While often asymptomatic, symptomatic cysts may cause nasal obstruction, postnasal drip, halitosis, occipital headache, or Eustachian tube dysfunction. Diagnosis relies on nasal endoscopy revealing a well-circumscribed cystic mass in the posterior nasopharynx. High-resolution CT assists by demonstrating a low-attenuation midline lesion, aiding differentiation from other masses. Histology confirms the diagnosis. Management is conservative for asymptomatic cases; symptomatic cysts require surgical excision or endoscopic marsupialization, with excellent outcomes and low recurrence rates.</div><div>We report a 25-year-old male with suspected obstructive sleep apnea syndrome and auditory symptoms. Imaging revealed a Tornwaldt cyst. Early diagnosis and multidisciplinary management are essential to optimize outcomes.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4738-4744"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonseminomatous mixed germ cell tumor of the testis: Case report","authors":"Azer Hafsi MD ,&nbsp;Fares El Hafsi MD ,&nbsp;Ayoub Bahria MD ,&nbsp;Aymen Namrouti MD ,&nbsp;Omaima Bkekri MD ,&nbsp;Asma Saadaoui MD ,&nbsp;Imen Ganzoui MD","doi":"10.1016/j.radcr.2025.06.045","DOIUrl":"10.1016/j.radcr.2025.06.045","url":null,"abstract":"<div><div>Testicular germ cell tumors (GCTs) are the most common solid malignancies in young males, with nonseminomatous germ cell tumors (NSGCTs) representing a significant subset characterized by aggressive behavior and elevated tumor markers. This case report highlights the diagnostic and therapeutic challenges in a young male with a history of surgically corrected testicular ectopy, presenting with progressive testicular enlargement and pain, ultimately diagnosed as a mixed NSGCT. A 25-year-old male presented with a 1-month history of right testicular enlargement and pain. Physical examination revealed a tender, enlarged right testicle. Laboratory investigations showed elevated tumor markers, including Alpha-fetoprotein (AFP: 1,200 ng/mL) and Beta-human chorionic gonadotropin (BHCG: 450 IU/L). Magnetic Resonance Imaging (MRI) of the scrotum was performed, including T2-weighted axial and coronal sequences, diffusion-weighted imaging (DWI), and dynamic contrast-enhanced imaging (DCE-MRI) with gadolinium. Radical inguinal orchiectomy was performed, and the resected specimen was subjected to histopathological examination. MRI revealed a large, heterogeneously hyperintense mass (50 × 50 × 45 mm) replacing the right testicular parenchyma, with irregular margins, hemorrhagic streaks, and low apparent diffusion coefficient (ADC) values (0.6 × 10⁻⁶ mm²/s). Dynamic postcontrast imaging demonstrated weak and progressive enhancement, consistent with NSGCT. Radical orchiectomy confirmed a grossly enlarged testicle with necrotic and hemorrhagic regions. Histopathology confirmed a mixed NSGCT, comprising embryonal carcinoma and yolk sac tumor components. Postoperative recovery was uneventful, and the patient was referred for further oncological management. This case underscores the importance of a multimodal diagnostic approach, integrating clinical evaluation, tumor markers, advanced imaging, and histopathology, in the management of testicular malignancies. Elevated AFP and BHCG levels were pivotal in raising suspicion for NSGCT, while MRI provided detailed characterization of the tumor’s size, internal architecture, and enhancement patterns, guiding surgical intervention. The histopathological findings confirmed the aggressive nature of the tumor, necessitating a multidisciplinary approach for further management. Early diagnosis and prompt intervention are critical for improving outcomes in patients with NSGCTs, particularly those with mixed histological components. This case highlights the pivotal role of MRI in diagnosing and staging testicular malignancies, complemented by tumor markers and histopathology. The integration of these modalities ensures accurate diagnosis and guides appropriate surgical and oncological management. Future studies should focus on refining imaging techniques and biomarkers to enhance diagnostic precision and personalize treatment strategies for testicular GCTs.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4745-4748"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemiazygos-accessory hemiazygos continuation of left-sided inferior vena cava: A case report and review of the literature","authors":"Nedasadat Rezaei ,&nbsp;Manizhe Ataee Kachuee ,&nbsp;Peyman Famili ,&nbsp;Ghazaleh Salehabadi","doi":"10.1016/j.radcr.2025.05.086","DOIUrl":"10.1016/j.radcr.2025.05.086","url":null,"abstract":"<div><div>Left side transposition of the inferior vena cava (IVC) is a rare anatomical variation formed during its complex embryonic developmental process. We present a 71-year-old female patient with an incidentally identified left-sided IVC in contrast-enhanced computed tomography during gastrointestinal bleeding workup. The left-sided IVC formed a hemiazygos-accessory hemiazygos continuation. A narrowing of the right retroaortic renal vein, consistent with the nutcracker phenomenon, was observed. Left-sided IVC, although asymptomatic in the majority of cases, may act as source of diagnostic confusion or contribute to deep vein thrombosis of lower extremities, especially in younger patients. Care must be practiced to establish a comprehensive diagnosis and minimize procedural risks.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4760-4767"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric hanging injury: Rapid intervention and full neurological recovery","authors":"Matyas Wondwossen Elssa MD ,&nbsp;Merahi Kefyalew Merahi MD ,&nbsp;Kebron Wossen Aweke MD ,&nbsp;Bement Girma Abera MD ,&nbsp;Kidist Nega Aragaw MD ,&nbsp;Kefelegn Negalign Mekuria MD ,&nbsp;Daniel Berhane Gebresilassie MD","doi":"10.1016/j.radcr.2025.06.007","DOIUrl":"10.1016/j.radcr.2025.06.007","url":null,"abstract":"<div><div>Hanging injuries are a subset of strangulation injuries that pose significant risks of hypoxia and neurological damage, especially in pediatric populations. This report presents a case of a 13-year-old boy with hypoxic brain injury following a suicide attempt by hanging. Key aspects include the prolonged duration of strangulation, absence of vertebral or laryngeal trauma, successful intensive care management, and full recovery without residual neurological deficits. This case emphasizes the importance of timely intervention, multidisciplinary management, and preventive education to address the acute and long-term challenges of pediatric hanging injuries.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4755-4759"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A hidden diagnosis: Axillary ectopic breast cancer presenting as progressive lymphadenopathy: A rare case report and literature review","authors":"Marouane Boukroute ,&nbsp;Abdelmajide Regragui ,&nbsp;Ibtissam Bellajdel ,&nbsp;Chetbi Zaineb ,&nbsp;Hafsa Taheri ,&nbsp;Hanane Saadi ,&nbsp;Ahmed Mimouni","doi":"10.1016/j.radcr.2025.06.011","DOIUrl":"10.1016/j.radcr.2025.06.011","url":null,"abstract":"<div><div>Ectopic breast cancer (EBC<strong>)</strong> is a rare malignancy arising from mammary tissue located outside the normal breast area, most commonly in the axilla. Its atypical presentation, often without associated breast abnormalities, can lead to delayed diagnosis. We describe the case of a 48-year-old woman presenting with progressive right axillary lymphadenopathy over 23 months. Imaging, including mammography and contrast-enhanced T1-weighted breast MRI, showed no identifiable primary breast lesion. Histopathological analysis of a core needle biopsy revealed undifferentiated carcinoma with positive hormonal receptor status, consistent with invasive lobular carcinoma arising from ectopic mammary tissue. The patient underwent neoadjuvant chemotherapy, surgical excision, axillary lymph node dissection, and received adjuvant radiotherapy and endocrine therapy. This case underscores the diagnostic challenge of EBC and highlights the importance of considering it in the differential diagnosis of axillary masses. Early histological confirmation and a multidisciplinary management approach are essential to optimize patient outcomes.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 9","pages":"Pages 4690-4694"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}