Journal of Electronic Science and Technology最新文献_第8页

Comparison of Khasi speech representations with different spectral features and hidden Markov states 不同谱特征和隐马尔可夫状态下卡西语语音表示的比较

Journal of Electronic Science and Technology Pub Date : 2021-06-01 DOI: 10.1016/j.jnlest.2020.100079

Bronson Syiem, Sushanta Kabir Dutta, Juwesh Binong, Lairenlakpam Joyprakash Singh

引用次数: 2

Perovskite single crystals: Synthesis, properties, and applications 钙钛矿单晶:合成、性质和应用

Journal of Electronic Science and Technology Pub Date : 2021-06-01 DOI: 10.1016/j.jnlest.2021.100081

Shan-Shan Rong , M. Bilal Faheem , Yan-Bo Li

引用次数: 30

Bioinformatics analysis on lncRNA and mRNA expression profiles for novel biological features of valvular heart disease with atrial fibrillation 心瓣膜病合并房颤的lncRNA和mRNA表达谱的生物信息学分析

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2020.100058

Wei Zeng , Ni-Ni Rao , Ke Liu

{"title":"Bioinformatics analysis on lncRNA and mRNA expression profiles for novel biological features of valvular heart disease with atrial fibrillation","authors":"Wei Zeng , Ni-Ni Rao , Ke Liu","doi":"10.1016/j.jnlest.2020.100058","DOIUrl":"10.1016/j.jnlest.2020.100058","url":null,"abstract":"<div><p>The biological features of the valvular heart disease with atrial fibrillation (AF-VHD) remain unknown when involving long non-coding RNAs (lncRNAs). This study performed system analysis on lncRNA and messenger RNA (mRNA) expression profiles constructed by using bioinformatics methods and tools for biological features of AF-VHD. Fold change and <em>t</em>-test were used to identify differentially expressed (DE) lncRNAs and mRNAs. The enrichment analysis of DE mRNAs was performed. The subgroups formed by lncRNAs and nearby mRNAs were screened, and a transcriptional regulation network among lncRNAs, mRNAs, and transcription factors (TFs) was constructed. The interactions between mRNAs related to lncRNAs and drugs were predicted. The 620 AF-VHD-related DE lncRNAs and 452 DE mRNAs were identified. The 3 lncRNA subgroups were screened. The 665 regulations mediated by lncRNAs and TFs were identified. The 9 mRNAs related to lncRNAs had 1 or more potential drug interactions, totaling 37 drugs. Of these, 9 drugs targeting 3 genes are already known to be able to control or trigger atrial fibrillation (AF) or other cardiac arrhythmias. The found biological features of AF-VHD provide foundations for further biological experiments to better understand the roles of lncRNAs in development from the valvular heart disease (VHD) to AF-VHD.</p></div>","PeriodicalId":53467,"journal":{"name":"Journal of Electronic Science and Technology","volume":"19 1","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnlest.2020.100058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45157720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Nonlinearity-compensation-free optical frequency domain reflectometry based on electrically-controlled optical frequency sweep 基于电控扫频的非线性无补偿光频域反射计

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2020.100025

Fan Yang, Ling-Jie Zhang, Zhi-Yao Zhang, Xiao-Jun Zhou, Yong Liu

{"title":"Nonlinearity-compensation-free optical frequency domain reflectometry based on electrically-controlled optical frequency sweep","authors":"Fan Yang, Ling-Jie Zhang, Zhi-Yao Zhang, Xiao-Jun Zhou, Yong Liu","doi":"10.1016/j.jnlest.2020.100025","DOIUrl":"10.1016/j.jnlest.2020.100025","url":null,"abstract":"<div><p>A nonlinearity-compensation-free optical frequency domain reflectometry (OFDR) scheme is proposed and experimentally demonstrated based on the electrically-controlled optical frequency sweep. In the proposed scheme, the linear frequency sweep light is generated by propagating an ultra-narrow-linewidth continuous-wave (CW) light through an electro-optic frequency shifter which consists of a dual-parallel Mach-Zehnder modulator (DPMZM) and an electronic 90° hybrid, where the electro-optic frequency shifter is driven by a linear frequency modulated signal generated by a direct digital synthesizer (DDS). Experimental results show that the spatial resolution and signal-to-noise ratio (SNR) of the proposed OFDR scheme without the nonlinear phase compensation are comparable to those of OFDR employing a commercial tunable laser source (TLS), an auxiliary interferometer, and a software-based nonlinear phase compensation method. The proposed OFDR scheme is helpful to reduce the complexity of the optical structure and eliminate the difficulty of developing the nonlinear phase compensation algorithm.</p></div>","PeriodicalId":53467,"journal":{"name":"Journal of Electronic Science and Technology","volume":"19 1","pages":"Article 100025"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnlest.2020.100025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46315597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Signal acquisition and processing method for capacitive electromagnetic flowmeter 电容式电磁流量计的信号采集与处理方法

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2020.100026

Hong-Yu Yang , Yan Chen , Hui Zhao

引用次数: 3

Impact of coronavirus pandemic crisis on technologies and cloud computing applications 冠状病毒大流行危机对技术和云计算应用的影响

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2020.100059

Ziyad R. Alashhab , Mohammed Anbar , Manmeet Mahinderjit Singh , Yu-Beng Leau , Zaher Ali Al-Sai , Sami Abu Alhayja’a

{"title":"Impact of coronavirus pandemic crisis on technologies and cloud computing applications","authors":"Ziyad R. Alashhab , Mohammed Anbar , Manmeet Mahinderjit Singh , Yu-Beng Leau , Zaher Ali Al-Sai , Sami Abu Alhayja’a","doi":"10.1016/j.jnlest.2020.100059","DOIUrl":"10.1016/j.jnlest.2020.100059","url":null,"abstract":"<div><p>In light of the COVID-19 outbreak caused by the novel coronavirus, companies and institutions have instructed their employees to work from home as a precautionary measure to reduce the risk of contagion. Employees, however, have been exposed to different security risks because of working from home. Moreover, the rapid global spread of COVID-19 has increased the volume of data generated from various sources. Working from home depends mainly on cloud computing (CC) applications that help employees to efficiently accomplish their tasks. The cloud computing environment (CCE) is an unsung hero in the COVID-19 pandemic crisis. It consists of the fast-paced practices for services that reflect the trend of rapidly deployable applications for maintaining data. Despite the increase in the use of CC applications, there is an ongoing research challenge in the domains of CCE concerning data, guaranteeing security, and the availability of CC applications. This paper, to the best of our knowledge, is the first paper that thoroughly explains the impact of the COVID-19 pandemic on CCE. Additionally, this paper also highlights the security risks of working from home during the COVID-19 pandemic.</p></div>","PeriodicalId":53467,"journal":{"name":"Journal of Electronic Science and Technology","volume":"19 1","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnlest.2020.100059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42530612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 61

Annotation of miRNAs in COVID-19 coronavirus COVID-19冠状病毒mirna的注释

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2020.100060

Tie-Ying Yu , Min Chen , Chun-De Wang

{"title":"Annotation of miRNAs in COVID-19 coronavirus","authors":"Tie-Ying Yu , Min Chen , Chun-De Wang","doi":"10.1016/j.jnlest.2020.100060","DOIUrl":"10.1016/j.jnlest.2020.100060","url":null,"abstract":"<div><p>The COVID-19 coronavirus is a new strain of coronavirus that had not been previously detected in humans. As its severe pathogenicity is concerned, it is important to study it thoroughly to aid in the discovery of a cure. In this study, the microRNAs (miRNAs) of COVID-19 were annotated to provide a powerful tool for the study of this novel coronavirus. We obtained 16 novel coronavirus genome sequences and the mature sequences of all viruses in the microRNA database (miRbase), and then used the miRNA mature sequences of the virus to perform the Basic Local Alignment Search Tool (BLAST) analysis in the coronavirus genome, extending the matched regions of approximately 20 bp to two segments by 200 bp. Six sequences were obtained after deleting redundant sequences. Then, the hairpin structures of the mature miRNAs were determined using RNAfold. The mature sequence on one hairpin arm was selected into a total of 4 sequences, and finally the relevant miRNA precursor prediction tools were used to verify whether the selected sequences are miRNA precursor sequences of the novel coronavirus. The miRNAs of the novel coronavirus were annotated by our newly developed method, which will lay the foundation for further study of this virus.</p></div>","PeriodicalId":53467,"journal":{"name":"Journal of Electronic Science and Technology","volume":"19 1","pages":"Article 100060"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnlest.2020.100060","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44741038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Image classification with superpixels and feature fusion method 超像素图像分类与特征融合方法

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2021.100096

Feng Yang, Zheng Ma, Mei Xie

引用次数: 15

Molecules against Covid-19: An in silico approach for drug development 抗Covid-19分子:一种用于药物开发的计算机方法

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2021.100095

Rhythm Bharti , Sandeep Kumar Shukla

{"title":"Molecules against Covid-19: An in silico approach for drug development","authors":"Rhythm Bharti , Sandeep Kumar Shukla","doi":"10.1016/j.jnlest.2021.100095","DOIUrl":"10.1016/j.jnlest.2021.100095","url":null,"abstract":"<div><p>A large number of deaths have been caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide, turning it into a serious and momentous threat to public health. This study tends to contribute to the development of effective treatment strategies through a computational approach, investigating the mechanisms in relation to the binding and subsequent inhibition of SARS-CoV-2 ribonucleic acid (RNA)-dependent RNA polymerase (RdRp). Molecular docking was performed to screen six naturally occurring molecules with antineoplastic properties (Ellipticine, Ecteinascidin, Homoharringtonine, Dolastatin 10, Halichondrin, and Plicamycin). Absorption, distribution, metabolism, and excretion (ADME) investigation was also conducted to analyze the drug-like properties of these compounds. The docked results have clearly shown binding of ligands to the SARS-CoV-2 RdRp protein. Interestingly, all ligands were found to obey Lipinski’s rule of five. These results provide a basis for repurposing and using molecules, derived from plants and animals, as a potential treatment for the coronavirus disease 2019 (COVID-19) infection as they could be effective therapeutics for the same.</p></div>","PeriodicalId":53467,"journal":{"name":"Journal of Electronic Science and Technology","volume":"19 1","pages":"Article 100095"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnlest.2021.100095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41774803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Identification of the potential function of circRNA in hypertrophic cardiomyopathy based on mutual RNA-RNA and RNA-RBP relationships shown by microarray data 基于微阵列数据显示的RNA-RNA和RNA-RBP相互关系鉴定circRNA在肥厚型心肌病中的潜在功能

Journal of Electronic Science and Technology Pub Date : 2021-03-01 DOI: 10.1016/j.jnlest.2021.100097

Guang-Bin Wang , Ni-Ni Rao , Chang-Long Dong , Xiao-Qin Lyu

{"title":"Identification of the potential function of circRNA in hypertrophic cardiomyopathy based on mutual RNA-RNA and RNA-RBP relationships shown by microarray data","authors":"Guang-Bin Wang , Ni-Ni Rao , Chang-Long Dong , Xiao-Qin Lyu","doi":"10.1016/j.jnlest.2021.100097","DOIUrl":"10.1016/j.jnlest.2021.100097","url":null,"abstract":"<div><p>The pathogenesis of hypertrophic cardiomyopathy (HCM) is very complicated, particularly regarding the role of circular RNA (circRNA). This research pays special attention to the relationships of the circRNA-mediated network, including RNA-RNA relationships and RNA-RNA binding protein (RNA-RBP) relationships. We use the parameter framework technology proposed in this paper to screen differentially expressed circRNA, messenger RNA (mRNA), and microRNA (miRNA) from the expression profile of samples related to HCM. And 31 pairs of circRNA and mRNA relationship pairs were extracted, combined with the miRNA targeting database; 145 miRNA-mRNA relationship pairs were extracted; 268 circRNA-mRNA-miRNA triads were established through the common mRNA in the 2 types of relationship pairs. Thus, 268 circRNA-miRNA regulatory relationships were deduced and 30 circRNA-RBP relationship pairs were analyzed at the protein level. On this basis, a circRNA-mediated regulatory network corresponding to the two levels of RNA-RNA and RNA-RBP was established. And then the roles of circRNA in HCM were analyzed through circRNA-mRNA, circRNA-miRNA, and circRNA-RBP, and the possible role in disease development was inferred.</p></div>","PeriodicalId":53467,"journal":{"name":"Journal of Electronic Science and Technology","volume":"19 1","pages":"Article 100097"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnlest.2021.100097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42892511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0