发布求助
文献互助 智能选刊 最新文献

Journal of the Japan Diabetes Society最新文献

筛选
英文 中文
第29回日本糖尿病学会総会記録 ワークショップ X 糖尿病と糖・ケトン体代謝 第29回日本糖尿病学会总会记录工作坊X糖尿病与糖·酮体代谢
Journal of the Japan Diabetes Society Pub Date : 1986-04-10 DOI: 10.11213/TONYOBYO1958.29.SPPL2_121
信夫 坂本
{"title":"第29回日本糖尿病学会総会記録 ワークショップ X 糖尿病と糖・ケトン体代謝","authors":"信夫 坂本","doi":"10.11213/TONYOBYO1958.29.SPPL2_121","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL2_121","url":null,"abstract":"","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63537924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of ICI 128, 436 on Animal Models of Neuropathy ICI 128、436对神经病变动物模型的影响
Journal of the Japan Diabetes Society Pub Date : 1986-04-05 DOI: 10.11213/TONYOBYO1958.29.SPPL1_41
D. Stribling, D. Tomlinson
{"title":"Effects of ICI 128, 436 on Animal Models of Neuropathy","authors":"D. Stribling, D. Tomlinson","doi":"10.11213/TONYOBYO1958.29.SPPL1_41","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_41","url":null,"abstract":"","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63535752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyols Accumulation and Effect of Aldose Reductase Inhibitor in STZ-Diabetic Rats 醛糖还原酶抑制剂对stz -糖尿病大鼠多元醇积累的影响
Journal of the Japan Diabetes Society Pub Date : 1986-04-05 DOI: 10.11213/TONYOBYO1958.29.SPPL1_34
D. Yue
{"title":"Polyols Accumulation and Effect of Aldose Reductase Inhibitor in STZ-Diabetic Rats","authors":"D. Yue","doi":"10.11213/TONYOBYO1958.29.SPPL1_34","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_34","url":null,"abstract":"The pathogenesis of diabetic neuropathy is incompletely understood. The accumulation of sorbitol has been postulated to be an important cause of the neuropthy. However, deficiency of myoinositol in diabetic peripheral nerves has also been documented and suggested as a cause of the neuropathy. The relative importance of sorbitol accumulation and myoinositol deficiency is not known and these two processes have usually been regarded as independent phenomena. In Streptozotocin diabetic rats, the centrations con of these two metabolites can be normalized by treatment with Sorbinil (5mg/kg body weight). These results suggest that the two processes are inter-related. The deficiency of nerve myoinositol can also be demonstrated in galactosaemic rats and again this can be normalized by aldose reductase inhibition. These results suggest that sorbitol or galactitol accumulations are primary events which lead to myoinositol deficiency. The finding of a relationship between sorbitol and myoinositol metabolism provide a unified concept relating the two abnormalities of diabetic nerve in the pathogenesis of diabetic neuropathy.","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63536019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitation of Neurologic Deficits in Diabetic Neuropathy 糖尿病神经病变中神经功能缺损的定量分析
Journal of the Japan Diabetes Society Pub Date : 1986-04-05 DOI: 10.11213/TONYOBYO1958.29.SPPL1_7
P. Dyck
{"title":"Quantitation of Neurologic Deficits in Diabetic Neuropathy","authors":"P. Dyck","doi":"10.11213/TONYOBYO1958.29.SPPL1_7","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_7","url":null,"abstract":"","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63537821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment Design of Neuropathy in Diabetes Control and Complications Trial (DCCT) in the U.S.A. 美国糖尿病控制及并发症试验(DCCT)中神经病变评估设计
Journal of the Japan Diabetes Society Pub Date : 1986-04-05 DOI: 10.11213/tonyobyo1958.29.sppl1_69
A. Douglas
{"title":"Assessment Design of Neuropathy in Diabetes Control and Complications Trial (DCCT) in the U.S.A.","authors":"A. Douglas","doi":"10.11213/tonyobyo1958.29.sppl1_69","DOIUrl":"https://doi.org/10.11213/tonyobyo1958.29.sppl1_69","url":null,"abstract":"","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63537710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heart Rate Variability for the Assessment of Autonomic Neuropathy 评估自主神经病变的心率变异性
Journal of the Japan Diabetes Society Pub Date : 1986-04-05 DOI: 10.11213/TONYOBYO1958.29.SPPL1_49
D. Ewing
{"title":"Heart Rate Variability for the Assessment of Autonomic Neuropathy","authors":"D. Ewing","doi":"10.11213/TONYOBYO1958.29.SPPL1_49","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_49","url":null,"abstract":"","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63536054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Evaluation of “Statil”. Pharmacokinetics and Biochemistry 施他汀的临床评价。药代动力学与生物化学
Journal of the Japan Diabetes Society Pub Date : 1986-04-05 DOI: 10.11213/TONYOBYO1958.29.SPPL1_100
R. Yates, C. Perkins, J. Kemp
{"title":"Clinical Evaluation of “Statil”. Pharmacokinetics and Biochemistry","authors":"R. Yates, C. Perkins, J. Kemp","doi":"10.11213/TONYOBYO1958.29.SPPL1_100","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_100","url":null,"abstract":"","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63535731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Early and Late Insulin Treatment on the Neuropathy in the BB-rat 早期和晚期胰岛素治疗对bb大鼠神经病变的影响
Journal of the Japan Diabetes Society Pub Date : 1986-04-05 DOI: 10.11213/TONYOBYO1958.29.SPPL1_42
A. Sima
{"title":"The Effects of Early and Late Insulin Treatment on the Neuropathy in the BB-rat","authors":"A. Sima","doi":"10.11213/TONYOBYO1958.29.SPPL1_42","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_42","url":null,"abstract":"","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63535813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence for Hypoxic Hypothesis of Diabetic Neuropathy 糖尿病性神经病变缺氧假说的证据
Journal of the Japan Diabetes Society Pub Date : 1986-01-01 DOI: 10.11213/TONYOBYO1958.29.SPPL1_26
P. Low
{"title":"Evidence for Hypoxic Hypothesis of Diabetic Neuropathy","authors":"P. Low","doi":"10.11213/TONYOBYO1958.29.SPPL1_26","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_26","url":null,"abstract":"We propounded the hypoxic hypothesis of diabetic neuropathy to reconcile morphologic descriptions of microangiopathy and descriptions of diffuse metabolic abnormalities in human (HDN) and experimental diabetic neuropathy (EDN). We have provided the following evidence for endoneurial hypoxia. 1) Indirect evidence of endoneurial hypoxia (reduced creatine phosphate; increased lactate)1) in acute and chronic experimental diabetic neuropathy.2)2) Reduced nerve blood flow (NBF) in chronic EDN2). 3) Direct evidence of endoneurial hypoxia based on microelectrode recordings of endoneurial oxygen tensions (PnO2) in chronic EDN. Sixty percent of oxygen tension values fell below the critical oxygen tension.2)3) 4) Oxygen supplementation partially prevented both the electrophysiologic and biochemical abnormalities in experimental diabetic neuropathy.3)5) To examine the role of sugar alcohol accumulation, PnO2 measurements were made in chronic experimental galactose neuropathy. Pn02 reduction occurred in proportion to the increase in intercapillary distance.4 6) To examine the role of hypoxia alone, rats were reared in a hypoxic (10% oxygen) environment for up to ten weeks. These animals developed nerve conduction slowing and RICB in the absence of sugar alcohol accumulation or myoinositol reduction. 7) Computer simulation studies are in good agreement with experimental data.","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63535885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitation of Postganglionic Sudomotor Function 神经节后运动功能的定量测定
Journal of the Japan Diabetes Society Pub Date : 1986-01-01 DOI: 10.11213/TONYOBYO1958.29.SPPL1_64
P. Low, B. Zimmerman, P. Dyck
{"title":"Quantitation of Postganglionic Sudomotor Function","authors":"P. Low, B. Zimmerman, P. Dyck","doi":"10.11213/TONYOBYO1958.29.SPPL1_64","DOIUrl":"https://doi.org/10.11213/TONYOBYO1958.29.SPPL1_64","url":null,"abstract":"Quantitation of cardiac vagal abnormalities can be accurately done using heart period measurements. Measurements of postganglionic sudomotor failure is now possible using the quantitative sudomotor axon reflex test (Q-SART)1). We performed Q-SART measurements on the forearm and proximal foot of 38 patients with diabetic neuropathy and 62 controls. These results were compared with HP measurements on the same patients. Responses to deep breathing (DB) and Valsalva maneuver (VM) were determined and BP was measured supine and standing. HP responses were abnormal to DB and VM in 71% and 63% of diabetics; both tests were abnormal in 58%. The Q-SART was abnormal in the foot in 66% of diabetics. Results of HP and Q-SART recordings were concordant in 66% of patients. 18% had abnormal HP but normal Q-SART recordings while 11% had abnormal Q-SART but normal HP. 31% of patients who had","PeriodicalId":53409,"journal":{"name":"Journal of the Japan Diabetes Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63537093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信