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Revista Romana de Boli Infectioase最新文献

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Management of the febrile neutropenic patient in 2023 2023年发热性中性粒细胞减少症患者的管理
Revista Romana de Boli Infectioase Pub Date : 2023-03-31 DOI: 10.37897/rjid.2023.1.1
D. Mangaloiu, Isabela-Daniela Staicu, A. Negru, V. Molagic, C. Tilișcan, Aida Adamescu, Oana Ganea, Laurențiu Stratan, Nicoleta Mihai, Ș. Aramă, V. Aramă
{"title":"Management of the febrile neutropenic patient in 2023","authors":"D. Mangaloiu, Isabela-Daniela Staicu, A. Negru, V. Molagic, C. Tilișcan, Aida Adamescu, Oana Ganea, Laurențiu Stratan, Nicoleta Mihai, Ș. Aramă, V. Aramă","doi":"10.37897/rjid.2023.1.1","DOIUrl":"https://doi.org/10.37897/rjid.2023.1.1","url":null,"abstract":"Febrile neutropenia (FN) is a well-known complication of chemotherapy (CHT) regimens, which appears more frequently in patients receiving CHT for hematologic malignancies, than those with solid tumors. Given the fact that this condition is life threatening, as well as multiple complications that may happen, rapid intervention is required, administration of empirical antibiotic therapy being necessary in the first hour of admission. Due to the high mortality rate associated with Pseudomonas aeruginosa infections, patients at risk should be given an antipseudomonal antibiotic agent, such as cefepime, carbapenem or piperacillin-tazobactam. Regarding empirical antibiotic coverage for gram-positive microorganisms, this is preserved for hypotensive patients, with skin/soft infections or suspected catheters infection or those taking fluoroquinolone. Considering the fact that a variety of bacterial, viral and fungal pathogens are responsible for high morbidity and mortality among patients with FN, preventable measures like antibiotic, antifungal and antiviral, as well as vaccination and prophylaxis with G-CSF, are crucial components in providing medical treatment for onco-hematological patients.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47177025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meningo encephalitis with Epstein-Barr virus in an immunocompetent adult patient: case report 一例免疫功能正常的成人患者伴有eb病毒的脑膜脑炎
Revista Romana de Boli Infectioase Pub Date : 2023-03-31 DOI: 10.37897/rjid.2023.1.3
Sabina-Lucia Ganea, M. Arbune, Daniela-Renata Santea, Catalina-Elena Radu, A. Arbune
{"title":"Meningo encephalitis with Epstein-Barr virus in an immunocompetent adult patient: case report","authors":"Sabina-Lucia Ganea, M. Arbune, Daniela-Renata Santea, Catalina-Elena Radu, A. Arbune","doi":"10.37897/rjid.2023.1.3","DOIUrl":"https://doi.org/10.37897/rjid.2023.1.3","url":null,"abstract":"Epstein - Barr virus is a rare ethology of the neurological infections, expressed as encephalitis, aseptic meningitis, Guillain-Barre syndrome or acute demyelinating encephalomyelitis. Most common cases were reported in children, while this infection is rarely described in immunocompetent adults. We present the case of an elderly immunocompetent patient with hypertension and hypothyroidism under treatment who has presented to the emergency department for unusual headache, confusion, sudden loss of consciousness with retrograde amnesia, suddenly onset for 2 hours associated with febrile respiratory symptoms. Traumatic neurological events, cerebral ischemia or metabolic encephalopathies were ruled out, while examination of the cerebrospinal fluid was positive for Epstein Barr Virus. The course of the meningoencephalitis was favorable, although an episode of diarrhea with Clostridioides difficile with binary positive toxin A+B was notified. The primary infection or the reactivation of a previous infection, is a questionable mechanism of meningoencephalitis with Epstein Barr Virus in an old immunocompetent patient. According to the reported studies, the antiviral treatment with Acyclovir is controversial. The long-term prognosis of acute meningoencephalitis with Epstein Barr Virus is unpredictable and involves careful neurological and onco-hematological monitoring.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43623430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Mechanism of biofilm formation in ESKAPE organism and their treatment ESKAPE生物膜形成机制及其处理
Revista Romana de Boli Infectioase Pub Date : 2022-12-31 DOI: 10.37897/rjid.2022.4.3
Apoorva Jain, P. K. Javaregowda, Kelmani Chandrakanth R, A. Oli
{"title":"Mechanism of biofilm formation in ESKAPE organism and their treatment","authors":"Apoorva Jain, P. K. Javaregowda, Kelmani Chandrakanth R, A. Oli","doi":"10.37897/rjid.2022.4.3","DOIUrl":"https://doi.org/10.37897/rjid.2022.4.3","url":null,"abstract":"One of the major global issues is the urgency of nosocomial infections, biofilm development, and antibiotic resistance. The ESKAPE pathogens are a significant factor in these problems (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species). These pathogens, often known as hospital-acquired infections (HAIs), are common in hospital settings and present one of the most significant difficulties in treatment. The development of biofilms, in which the microbial cells adapt to a multicellular lifestyle by getting trapped inside the extracellular polymeric matrix, is a key biological concept in clinical contexts. For the creation of novel antimicrobial agents, as well as for the repurposing of currently accessible medications or pre-clinical substances and the broader use of combination therapies, it is essential to comprehend the process by which these bacteria build biofilms. The Pathomechanisms of these bacterial biofilm formations and alternate strategies to prevent biofilm formation in hospital management are highlighted in this review.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48178003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circumferential upper extremities burn, bilateral Dupuytren's disease and COVID-19 disease – an unfavorable triad: a case report 上肢周围烧伤、双侧Dupuytren's病和新冠肺炎病——一种不利的三联征：病例报告
Revista Romana de Boli Infectioase Pub Date : 2022-12-31 DOI: 10.37897/rjid.2022.4.1
T. Neagu, Sabina Grama, M. Tiglis, I. Lascar
{"title":"Circumferential upper extremities burn, bilateral Dupuytren's disease and COVID-19 disease – an unfavorable triad: a case report","authors":"T. Neagu, Sabina Grama, M. Tiglis, I. Lascar","doi":"10.37897/rjid.2022.4.1","DOIUrl":"https://doi.org/10.37897/rjid.2022.4.1","url":null,"abstract":"Upper extremities are frequently involved in fire burns due to the natural protective reflexes. The presence of bilateral Dupuytrenʼs disease and COVID-19 disease in patients with circumferential upper extremity burns can negatively impact the outcome, through severe contracture and a tendency to hypoxia or infections, which affects normal wound healing. Enzymatic debridement with a concentrate of proteolytic enzymes enriched in bromelain prevents compartment syndrome development in such patients, reduces blood loss, surgery duration, and appears to favor a more rapid recovery.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48079465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report 新生儿单纯疱疹病毒感染的处理在一个小胎龄新生儿-病例报告
Revista Romana de Boli Infectioase Pub Date : 2022-12-31 DOI: 10.37897/rjid.2022.4.2
Maria-Andreea Racean, L. Suciu, C. Mărginean
{"title":"The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report","authors":"Maria-Andreea Racean, L. Suciu, C. Mărginean","doi":"10.37897/rjid.2022.4.2","DOIUrl":"https://doi.org/10.37897/rjid.2022.4.2","url":null,"abstract":"Neonatal herpes simplex virus infections are rare, normally acquired through vertical transmission in the peripartum period, usually manifesting before 14 days of life and being identified on the basis of history, clinical and laboratory evaluation. We present the case of a small for gestational age male infant born at 38 weeks gestational age with neonatal herpes simplex virus infection. The diagnosis was delayed because the attention was focused on an unidentified bacterial infection. In cases where a clinical picture suggestive of infection is described, with laboratory tests that support the diagnosis of infection, but with cultures that do not highlight bacterial or mycological agents, we must not forget about viral agents, specifically among those newborns from intrauterine growth restricted pregnancies. Neonatal HSV infections can be present even in the absence of herpetic vesicles in the newborn and even if the mother is asymptomatic.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43555257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic spinal lymphoma: A case report 转移性脊髓淋巴瘤1例报告
Revista Romana de Boli Infectioase Pub Date : 2022-12-31 DOI: 10.37897/rjid.2022.4.4
R. Pinzon, Patrick Kurniawan Latumahina
{"title":"Metastatic spinal lymphoma: A case report","authors":"R. Pinzon, Patrick Kurniawan Latumahina","doi":"10.37897/rjid.2022.4.4","DOIUrl":"https://doi.org/10.37897/rjid.2022.4.4","url":null,"abstract":"Background. Metastatic spinal lymphoma is a rare case, especially with the initial clinical manifestation of back pain, which only occurs in less than 5% of patients. We report a case of an adult male with low back pain that was found to be metastatic spinal lymphoma, and this study is the first to report a case of metastatic spinal lymphoma with initial complaints of back pain. Case Presentation. A 66-year-old male presented with progressive lower extremity weakness since 2 weeks. The initial complaint was back pain since 2 months before admission. The patient had no history of previous trauma, history of hypertension, diabetes, or heart disease was also denied. The patient admitted that there was a weight loss in the last 2-3 months Radiologic examination of the lumbar spinal MRI (magnetic resonance imaging) without contrast was performed and showed an impression of bone metastasis at the corpus VL (lumbar vertebrae) 1-5, and paraspinal muscular spasm. Conclusion. We report rare case of metastatic spinal lymphoma, spinal lymphoma should be considered and monitored for non-specific clinical findings that resemble other possible causes.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44498526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of ENT manifestation in COVID-19 patients 耳鼻喉科表现对新冠肺炎患者的影响
Revista Romana de Boli Infectioase Pub Date : 2022-09-30 DOI: 10.37897/rjid.2022.3.4
Bogdan-Alexandru Georgescu, Bianca Neagu, Andrei Osman, Carmen Liana Mocanu, S. Rugina
{"title":"The impact of ENT manifestation in COVID-19 patients","authors":"Bogdan-Alexandru Georgescu, Bianca Neagu, Andrei Osman, Carmen Liana Mocanu, S. Rugina","doi":"10.37897/rjid.2022.3.4","DOIUrl":"https://doi.org/10.37897/rjid.2022.3.4","url":null,"abstract":"The pandemic with the new coronavirus – SARS-CoV-2 – has caused extraordinary changes in our way of life. Infection with this virus has caused a huge number of diseases worldwide. After healing from this infection, many patients continued to show symptoms at a distance after the infection itself. SARS-CoV-2 virus infection is mainly manifested by symptoms related to the lower respiratory tract, such as fever, cough, dyspnea and chest pressure, which could rapidly evolve to acute respiratory distress syndrome (SARS). However, COVID-19 also causes various symptoms related to the upper respiratory tract, including nasal congestion, neck pain and olfactory dysfunction. We aim to review, analyze and compare small-looking research studies. Studies show what the changes in ENT are in COVID-19 pandemic disease, how these symptoms influence the course of the disease and how much immuno-depressed the patient this virus.it is found that this virus leaves a very precarious immune system and leaves serious consequences in terms of activating some pathologies and symptoms. We also intend to present an atypical case of a patient infected with the SARS-CoV-2 virus that showed a multitude of ENT manifestations both during the acute state and after healing.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45156069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Waiting for the 7th wave of the pandemic: analysis of the COVID-19 cases from ”Victor Babes” Hospital, Craiova 等待第七波大流行:克拉约瓦“维克多宝贝”医院COVID-19病例分析
Revista Romana de Boli Infectioase Pub Date : 2022-09-30 DOI: 10.37897/rjid.2022.3.3
L. Giubelan, F. Dumitrescu, I. Diaconescu, M. Forțofoiu, I. Cristina, Georgescu Ilona
{"title":"Waiting for the 7th wave of the pandemic: analysis of the COVID-19 cases from ”Victor Babes” Hospital, Craiova","authors":"L. Giubelan, F. Dumitrescu, I. Diaconescu, M. Forțofoiu, I. Cristina, Georgescu Ilona","doi":"10.37897/rjid.2022.3.3","DOIUrl":"https://doi.org/10.37897/rjid.2022.3.3","url":null,"abstract":"COVID-19 is an ongoing pandemic and an analysis of the cases treated in ”Victor Babes” Hospital of Infectious Diseases and Pulmonology from Craiova between March 2020 and October 2022 has been performed.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":"155 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41282773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new pandemic – new questions: postnatal care of infants born to mothers with suspected or confirmed COVID-19 新的大流行——新的问题:疑似或确诊COVID-19母亲所生婴儿的产后护理
Revista Romana de Boli Infectioase Pub Date : 2022-09-30 DOI: 10.37897/rjid.2022.3.2
Lia Spoiala, Maura-Adelina Hincu, G. Zonda, Anda-Ioana Avasilcai, Cristina Gavrilovici, Vlad Dima, L. Păduraru
{"title":"A new pandemic – new questions: postnatal care of infants born to mothers with suspected or confirmed COVID-19","authors":"Lia Spoiala, Maura-Adelina Hincu, G. Zonda, Anda-Ioana Avasilcai, Cristina Gavrilovici, Vlad Dima, L. Păduraru","doi":"10.37897/rjid.2022.3.2","DOIUrl":"https://doi.org/10.37897/rjid.2022.3.2","url":null,"abstract":"COVID-19 infection is primarily a community-acquired airborne respiratory infection, making pediatric and neonatal populations extremely vulnerable to the disease. Since the beginning of the coronavirus pandemic, many questions regarding mother and infant health have arisen, one of the most discussed issues being the management of infants born to mothers with suspected or confirmed COVID-19. Is it advisable to separate the child from the positive mother immediately after birth? What are the recommendations for breastfeeding? Are there any short and long-term follow-up indications or are there any possible long-term complications that we should take into account in those children? And not lastly, what are the most respectful and ethical measures both for mother and infant? We aim to analyze and compare the existing guidelines regarding the management of infants born to mothers with suspected or confirmed COVID-19 and to discuss the similarities and discrepancies between the available protocols.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45950158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sneathia infections and adverse perinatal outcomes – short communication Sneathia感染和不良围产期结果——简短沟通
Revista Romana de Boli Infectioase Pub Date : 2022-09-30 DOI: 10.37897/rjid.2022.3.1
V. Varlas, Vlad Dima, R. Bors
{"title":"Sneathia infections and adverse perinatal outcomes – short communication","authors":"V. Varlas, Vlad Dima, R. Bors","doi":"10.37897/rjid.2022.3.1","DOIUrl":"https://doi.org/10.37897/rjid.2022.3.1","url":null,"abstract":"The influence of the maternal vaginal microbiome in vaginal birth is an important factor in the pathogenesis of early-onset neonatal sepsis. The incidence of Sneathia infection is hard to assess due to the difficulty in its detection, as special culture conditions are required. The laboratory methods used in its detection are based on molecular analysis. This emergent, anaerobic agent, by ascending from the female genital tract, can colonize and infect the amniotic fluid, fetal membranes, and placenta. Chorioamnionitis, neonatal sepsis, stillbirth, spontaneous premature labor, and preterm prelabour rupture of the membrane are some of the adverse reactions that can be associated with the presence of Sneathia. In conclusion, Sneathia infection, although underestimated due to its virulence, represents an increased risk of maternal-fetal infections, with the risk of developing a series of neonatal complications. The detection and treatment of this infection will contribute to a decrease in neonatal morbidity and mortality.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46793611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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