Nucleus (India)最新文献_第8页

Morpho-molecular characterization of rock-inhabiting lichen Dermatocarpon miniatum (Verrucariaceae, Ascomycota) and its symbiont in Indian Himalayas 印度喜马拉雅地区岩栖地衣(疣状菌科，子囊菌科)及其共生体的形态-分子特征

IF 1.8

Nucleus (India) Pub Date : 2021-03-24 DOI: 10.1007/s13237-021-00349-0

K. C. Saini, F. Bast, Sanjeeva Nayaka, A. Gautam

引用次数: 3

Genomic territories in inter-genomic hybrids: the winners and losers with hybrid fixation 基因组间杂交中的基因组区域：杂交固定的赢家和输家

IF 1.8

Nucleus (India) Pub Date : 2021-02-16 DOI: 10.1007/s13237-021-00348-1

Y. Vimala, U. C. Lavania

引用次数: 5

Modulatory role of tea in arsenic induced epigenetic alterations in carcinogenesis 茶对砷致癌表观遗传改变的调节作用

IF 1.8

Nucleus (India) Pub Date : 2021-01-19 DOI: 10.1007/s13237-020-00346-9

Archismaan Ghosh, S. Mukherjee, M. Roy, A. Datta

引用次数: 2

A report of intraspecific polyploidy (4x, 6x) in Festuca gigantea (L.) Vill (Family: Poaceae) from Western Himalaya, India and comments on its cyto-geography 印度喜马拉雅西部大羊茅（科：禾本科）种内多倍体（4x，6x）的报道及其细胞地理学评价

IF 1.8

Nucleus (India) Pub Date : 2021-01-03 DOI: 10.1007/s13237-020-00347-8

V. Kumari, Jaswant Singh, V. Singhal

引用次数: 0

Is it possible to ensure COVID19 vaccine supply by using plants? 是否可以通过植物来确保covid - 19疫苗的供应?

IF 1.8

Nucleus (India) Pub Date : 2021-01-01 Epub Date: 2021-07-02 DOI: 10.1007/s13237-021-00361-4

Anirban Bhar

{"title":"Is it possible to ensure COVID19 vaccine supply by using plants?","authors":"Anirban Bhar","doi":"10.1007/s13237-021-00361-4","DOIUrl":"https://doi.org/10.1007/s13237-021-00361-4","url":null,"abstract":"Any disease that spreads quickly and crossed the geographical barrier is termed as pandemic. After the initial occurrence of Covid-19 from China, World Health Organization had declared novel corona viral outbreak as pandemic on March, 2020. Since then, COVID-19 continued to devastate people all around the world. Human civilization has witnessed one of its greatest crises by facing 180 million of confirmed cases with 38.9 lakh deaths across the world till end of June 2021. India alone contributes 30 million of positive cases and has lost 3.92 lakh valuable lives (data as on 24th of June 2021 from CSSEGIS and Data (http://github.com/CSSEGISandData/COVID-19); (the number increases in each day). Bio-medical experts from all around the world are working tirelessly to limit the disease and find potential cures for this viral infection. Vaccination is the most effective strategy to prevent the spread of any viral disease. Virologists have developed some effective vaccines, but production or supply lags far behind the present demand across the globe. Plant-derived vaccines (PDVs) based on modified virus like particles (VLPs) can be a feasible alternative in this case. A summarized account about the efficacy of the first plant-derived Covid 19 vaccine, CoVLP is discussed. PDVs and VLPs are also reviewed briefly, along with their benefits and drawbacks.","PeriodicalId":53176,"journal":{"name":"Nucleus (India)","volume":"64 2","pages":"137-141"},"PeriodicalIF":1.8,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13237-021-00361-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39173318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Regulation of autophagy by miRNAs in human diseases. mirna在人类疾病中对自噬的调控。

IF 1.8

Nucleus (India) Pub Date : 2021-01-01 Epub Date: 2021-10-16 DOI: 10.1007/s13237-021-00378-9

Sounak Ghosh Roy

{"title":"Regulation of autophagy by miRNAs in human diseases.","authors":"Sounak Ghosh Roy","doi":"10.1007/s13237-021-00378-9","DOIUrl":"https://doi.org/10.1007/s13237-021-00378-9","url":null,"abstract":"Autophagy is a homeostatic process designed to eliminate dysfunctional and aging organelles and misfolded proteins through a well-concerted pathway, starting with forming a double-membrane vesicle and culminating in the lysosomal degradation of the cargo enclosed inside the mature vesicle. As a vital sentry of cellular health, autophagy is regulated in every human disease condition and is an essential target for non-coding RNAs like microRNAs (miRNAs). miRNAs are short oligonucleotides that specifically bind to the 3'-untranslated region (UTR) of target mRNAs, thus leading to mRNA silencing, degradation, or translation blockage. This review summarizes the recent findings regarding the regulation of autophagy and autophagy-related genes by different miRNAs in various pathological conditions, including cancer, kidney and liver disorders, neurodegeneration, cardiovascular disorders, infectious diseases, aging-related conditions, and inflammation-related diseases. As miRNAs are being identified as prime regulators of autophagy in human disease, pharmacological molecules and traditional medicines targeting these miRNAs are also being tested in disease models, thus initiating a new series of therapeutic interventions targeting autophagy.","PeriodicalId":53176,"journal":{"name":"Nucleus (India)","volume":" ","pages":"317-329"},"PeriodicalIF":1.8,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39551657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Establishment of a testis cell line from Clarias magur: a potential resource for in-vitro applications Clarias magur睾丸细胞系的建立:体外应用的潜在资源

IF 1.8

Nucleus (India) Pub Date : 2021-01-01 DOI: 10.1007/s13237-020-00345-w

Neha Singh, P. Soni, B. Kushwaha, M. S. Kumar, J. K. Srivastava, S. Srivastava, Akhilesh Kumar Mishra, Ravindra Kumar

引用次数: 2

Individual chromosome identification in Clarias magur using BAC-FISH and comparative genes analyses 应用BAC-FISH和比较基因分析法鉴定克拉藻个体染色体

IF 1.8

Nucleus (India) Pub Date : 2020-11-21 DOI: 10.1007/s13237-020-00344-x

Ravindra Kumar, V. Baisvar, B. Kushwaha, M. Pandey, Mahender Singh

引用次数: 1

Omics of neglected and underutilized crop species: one small step for NUCS, one giant leap for addressing global hunger 被忽视和未充分利用的作物物种组学:NUCS的一小步，解决全球饥饿问题的一大步