Nepalese Medical Journal最新文献_第2页

Patient’s Involvement, Engagement, and Participation in Medical Research: Nepalese Perspective 病人参与、参与和参与医学研究:尼泊尔视角

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.47142

A. Dhakal, D. Shrestha

引用次数: 0

Comparative Study of Modified Alvarado Score and Eskelinen Score in Diagnosing Acute Appendicitis 改良Alvarado评分与Eskelinen评分诊断急性阑尾炎的比较研究

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.42868

Isha Dahal

{"title":"Comparative Study of Modified Alvarado Score and Eskelinen Score in Diagnosing Acute Appendicitis","authors":"Isha Dahal","doi":"10.3126/nmj.v5i1.42868","DOIUrl":"https://doi.org/10.3126/nmj.v5i1.42868","url":null,"abstract":"Introduction: Despite many advances in diagnosis, diagnosing appendicitis remains difficult. Various diagnostic scoring systems have been developed in an attempt to improve the diagnostic accuracy of acute appendicitis. The study aimed to determine the accuracy of the Modified Alvarado and Eskelinen score in diagnosing acute appendicitis and to correlate the histopathological findings with the severity of acute appendicitis.\u0000Materials and Methods: A prospective study was conducted in TUTH including 84 patients with a clinical diagnosis of acute appendicitis managed surgically for 10 months. Modified Alvarado and Eskelinen Score were calculated and histopathological findings were correlated for predicting the severity of appendicitis.\u0000Results: Out of 84 patients Modified Alvarado Score had sensitivity and specificity of 67.79% and 32% when the score was taken as 7 and Eskelinen Score had sensitivity and specificity of 70.17% and 29.62% when the score was taken as 55. However, the sensitivity of the Modified Alvarado Score increased to 92.85% and specificity to 14.28% when the cut-off score was taken as 6. Modified Alvarado Score predicted 67% and 63% of uncomplicated and complicated appendicitis respectively and Eskelinen Score predicted 72% of uncomplicated and 67% of complicated appendicitis when the score was taken as 7 and 55 respectively.\u0000Conclusions: Both Modified Alvarado and Eskelinen Scores have low sensitivity in diagnosing acute appendicitis. With cut off for Modified Alvarado Score taken as 6, sensitivity increased. There was no correlation between the severity of appendicitis with the increase in Modified Alvarado and Eskelinen Score.","PeriodicalId":52856,"journal":{"name":"Nepalese Medical Journal","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78471513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pap Smear as a Screening Tool for Cervical Cancer in a Tertiary Care Centre in Nepal: A Retrospective Cross-sectional Analysis 巴氏涂片作为宫颈癌筛查工具在尼泊尔三级保健中心:回顾性横断面分析

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.46421

A. Shrestha, A. Adhikari, A. Poudel, B. Aryal, Ganesh Parajuli, S. Gurung, Shreejana Baskota, Ishu Shrestha

{"title":"Pap Smear as a Screening Tool for Cervical Cancer in a Tertiary Care Centre in Nepal: A Retrospective Cross-sectional Analysis","authors":"A. Shrestha, A. Adhikari, A. Poudel, B. Aryal, Ganesh Parajuli, S. Gurung, Shreejana Baskota, Ishu Shrestha","doi":"10.3126/nmj.v5i1.46421","DOIUrl":"https://doi.org/10.3126/nmj.v5i1.46421","url":null,"abstract":"Introduction: Pap smear is a time-tested screening test to diagnose cervical carcinoma at an early stage. It allows clinicians to take intervention measures, prevent the progression of the disease to invasive forms and decrease the burden of carcinoma as a whole. The objective of this study is to determine the values regarding the diagnostic accuracy of Pap smear and establish its role in the health care setting of Nepal.\u0000Materials and Methods: This is a retrospective cross-sectional analysis of the records from April 14, 2018, to April 12, 2020, of the Department of Pathology in a tertiary care hospital in the capital city of Nepal. Ethical approval for the study was taken from the Institutional Review Board and the demographic and clinical data of patients were analyzed anonymously. The consecutive sampling technique as used for data collection and analysis was done in Microsoft Excel 2019 and Statistical Packages for Social Sciences Version 25. The diagnostic accuracy parameters were calculated from a contingency table prepared from the collected data.\u0000Results: Out of 3095 Pap smears, 72 had a positive finding of some sort. 74 cases had a positive finding in the form of a biopsy out of 573. The sensitivity, specificity, positive predictive value, and negative predictive value of Pap smear at the institution were found to be 0.70, 0.94, 0.78, and 0.91 respectively with an overall accuracy of 88.36%.\u0000Conclusions: Pap smear can still play a pivotal role in the diagnosis of cervical neoplastic lesions.","PeriodicalId":52856,"journal":{"name":"Nepalese Medical Journal","volume":"235 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87506660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advancements in Oral Anticoagulants: A Systematic Review 口服抗凝血剂的最新进展:系统综述

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.44920

Ramica Sharma

引用次数: 0

Use of Brain Stimulation to Improve Swallowing in a Brainstem Stroke Patient with Cricopharyngeal Spasm: Case Report 脑刺激改善脑干卒中伴环咽痉挛患者吞咽:1例报告

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.42251

Tanvi Sanghavi

引用次数: 0

Blepharoptosis: Pattern and its Surgical Management in a Tertiary Eye Hospital of Eastern Nepal 上睑下垂:尼泊尔东部一家三级眼科医院的模式及其外科治疗

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.44429

Prerna Arjyal Kafle, D. Hamal, Sabin Sahu, Sharmila Chaudhary

{"title":"Blepharoptosis: Pattern and its Surgical Management in a Tertiary Eye Hospital of Eastern Nepal","authors":"Prerna Arjyal Kafle, D. Hamal, Sabin Sahu, Sharmila Chaudhary","doi":"10.3126/nmj.v5i1.44429","DOIUrl":"https://doi.org/10.3126/nmj.v5i1.44429","url":null,"abstract":"Introduction: Blepharoptosis or drooping of the eyelid is a common disease entity presenting in oculoplasty department. Depending on its severity it causes visual disturbances as well as cosmetic problems. Appropriate management and timely surgical intervention results in a good outcome.\u0000Materials and methods: This is a hospital-based study of a blepharoptosis patient that presented in the Oculoplasty department and underwent ptosis correction by various methods from July 2016- December 2019.\u0000Results: A total of 85 cases with 104 eyes underwent ptosis surgery. The mean age was 24.5 years. Among them, 31.8% were pediatric and 68.2% were adults. Astigmatism was seen in 21.1% followed by myopia in 10.6% and hypermetropia in 4.7%. Amblyopia was seen in 13% of cases. Common surgical procedures performed were frontalis sling suspension 64.7%, followed by levator advancement 33%, and frontalis sling surgery with V-Y plasty 2.3%.\u0000Conclusions: Ptosis is seen to be associated with refractive errors, strabismus, or amblyopia. Proper clinical evaluation of the patient is essential to know the etiology, type, and severity of ptosis. Timely surgical intervention is necessary to prevent morbidity and enhance its outcome.","PeriodicalId":52856,"journal":{"name":"Nepalese Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80416653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic Role of Image-Guided Fine Needle Aspiration Cytology 影像引导下细针穿刺细胞学的诊断作用

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.46803

P. Sherpa, Sudhamsu Koirala

{"title":"Diagnostic Role of Image-Guided Fine Needle Aspiration Cytology","authors":"P. Sherpa, Sudhamsu Koirala","doi":"10.3126/nmj.v5i1.46803","DOIUrl":"https://doi.org/10.3126/nmj.v5i1.46803","url":null,"abstract":"Introduction: With the aid of modern imaging procedures like ultrasonography and computed tomography, fine needle aspiration cytology of deeper structures, small and vaguely palpable swellings, and lesions that are in close proximity to major vasculature are feasible. This study aims to establish the prevalence of image-guided FNAC, evaluate its diagnostic utility, and assess the spectrum of disorders diagnosed with its usage.\u0000Materials and Methods: A retrospective descriptive study was performed in the Pathology department, Om Hospital, and Research Centre from May 2015 to November 2019. The study included all samples of image-guided FNACs which were received for cytological examination.\u0000Results: Image-guided FNAC accounted for 13.03% of all FNACs done during the study period. Female predominance with a male to female ratio of 1:1.4 was noted. The age of the patients ranged from 13 to 85 years with a mean age of 53.6 years. The majority of the FNACs were performed under USG guidance. The lung was the most commonest site followed by lymph nodes and liver. Cytological diagnosis was made in 225 (88.93%) of the total cases. 7 (2.77%) cases were suspicious for malignancy and 21 (8.3%) were inconclusive. The majority of the lesions were categorized as malignant.\u0000Conclusions: Image-guided FNAC has a good diagnostic yield for deeper structures and small and vaguely palpable swellings. A spectrum of lesions, both neoplastic and non-neoplastic can be diagnosed with its usage. The commonest site of aspiration was the lung followed by lymph nodes and liver.","PeriodicalId":52856,"journal":{"name":"Nepalese Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81000186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lack of an Association or an Inverse Association Between Cholesterol and Coronary Artery Disease: A Case-Control Study 胆固醇与冠状动脉疾病之间缺乏相关性或负相关性:一项病例对照研究

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.46471

Sanjay Shrestha, Nikky Maharjan

{"title":"Lack of an Association or an Inverse Association Between Cholesterol and Coronary Artery Disease: A Case-Control Study","authors":"Sanjay Shrestha, Nikky Maharjan","doi":"10.3126/nmj.v5i1.46471","DOIUrl":"https://doi.org/10.3126/nmj.v5i1.46471","url":null,"abstract":"Introduction: Cholesterol has been blamed as the principal cause of cardiovascular diseases, however, it is a common observation that most coronary artery disease patients do not have strikingly high cholesterol values, often falling within the desirable range, and also many patients with high cholesterol levels do not have any atherosclerotic cardiovascular diseases. Therefore, we decided to investigate whether there is an association between cholesterol levels and coronary artery disease. \u0000Materials and Methods: This is a case-control study conducted on a total of 313 coronary heart disease patients and 369 controls diagnosed by coronary angiogram. Fasting lipid profile was analyzed for both cases and controls. The study extended for a period of three years from 2018 July to 2020 June.\u0000Results: Total cholesterol (p<0.05) and Low-Density Lipoprotein (p<0.05) levels were significantly lower among the cases, while triglyceride and High-Density Lipoprotein levels of cases were similar to the controls.\u0000Taking age into consideration, there was no significant difference in the total cholesterol and Low-Density Lipoprotein levels between cases and controls below the age of 60 years, however, above the age of 60 years, total cholesterol and Low-Density Lipoprotein were significantly lower in the cases (p<0.05).\u0000Conclusions: The findings of the present study indicated that either there was no association between cholesterol levels and coronary artery disease or an inverse association when age was taken into consideration, as above 60 years of age the cholesterol level was found to be significantly lower in the patients of coronary artery disease compared to controls.","PeriodicalId":52856,"journal":{"name":"Nepalese Medical Journal","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89889916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Speech-language Pathologist: A Team Member for Management of Head and Neck Cancer Patients 语言病理学家:头颈癌患者管理团队成员

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.37741

Biraj Bhattarai

引用次数: 0

Recurrence of Renal Hydatid Cyst 肾包虫病复发

Nepalese Medical Journal Pub Date : 2022-06-30 DOI: 10.3126/nmj.v5i1.43175

R. B. Basnet, Prabodh Regmi, Baikuntha Adhikari, B. B. Gharti, S. Basnet, Udita Mishra

引用次数: 0