Case Reports in Critical Care最新文献

{"title":"A Case Report of Meningitis with Possible Coinfection by <i>Listeria monocytogenes</i> and <i>Mycobacterium tuberculosis</i> (Detected by Metagenomic Next-Generation Sequencing) and Literature Review.","authors":"Hongyin Zhu, Pan Yang, Yunxia Tu, Xiaoyu Fu, Xian Yang, Na An","doi":"10.1155/crcc/9615951","DOIUrl":"10.1155/crcc/9615951","url":null,"abstract":"<p><strong>Rationale: </strong>The study is aimed at exploring the complex clinical scenario of a patient with systemic lupus erythematosus who developed a rare coinfection with <i>Listeria monocytogenes</i> and <i>Mycobacterium tuberculosis</i>. The rationale is to highlight the diagnostic and therapeutic challenges in managing such a case, particularly in the context of immunosuppression and the need for effective antimicrobial therapy. This case underscores the importance of advanced diagnostic techniques like metagenomic next-generation sequencing in identifying coinfections and the critical balance required in treating both infections while managing the underlying autoimmune condition.</p><p><strong>Patient concerns: </strong>This case report presents a 58-year-old female patient who initially manifested thrombocytopenia and was diagnosed with SLE in an external hospital. After treatment, her condition did not improve. On the contrary, she developed a fever and a headache, and her disturbance of consciousness gradually worsened. The patient was admitted to our hospital with a suspected diagnosis of lupus encephalopathy and central nervous system infection.</p><p><strong>Diagnoses: </strong>MRI plain scan showed linear enhancement shadows in the right temporal pole and bilateral cerebellar hemisphere regions on the fluid-attenuated inversion recovery three-dimensional volumetric fluid-attenuated inversion recovery contrast-enhanced scan. Subsequently, NGS of the cerebrospinal fluid detected <i>L. monocytogenes</i> and <i>M. tuberculosis</i>, suggesting a possible mixed infectious meningitis caused by these two pathogens.</p><p><strong>Interventions: </strong>The patient underwent a comprehensive treatment regimen including anti<i>Listeria</i> and antituberculosis therapies. Unfortunately, this was followed by the development of liver failure and various other complications. In response, we administered interventions such as blood purification and liver support measures. Furthermore, we organized a multidisciplinary consultation to address the complex medical needs of the patient.</p><p><strong>Outcomes: </strong>Despite aggressive medical interventions, the patient's condition deteriorated. She developed multiorgan failure, which significantly impacted her prognosis. The patient's family elected to withdraw life-sustaining treatment, and the patient passed away within 24 h after discharge.</p><p><strong>Lessons: </strong>This case underscores the importance of early and accurate diagnosis, particularly for immunocompromised patients with complex clinical presentations. Identifying mixed infections is crucial, and it also poses a significant challenge in selecting appropriate antimicrobial agents and conducting relevant tests.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"9615951"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13323847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148377941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical Care Management Considerations in <i>Klebsiella pneumoniae</i> Invasive Liver Abscess Syndrome: Case Reports and Narrative Review.","authors":"Jerry Chen, Caleigh Horan, Krishen Wadhwani, Pedro M Dammert, Elizabeth Sophy","doi":"10.1155/crcc/5579095","DOIUrl":"10.1155/crcc/5579095","url":null,"abstract":"<p><strong>Importance: </strong><i>Klebsiella pneumoniae</i> invasive liver abscess syndrome (ILAS) is an emerging disease characterized by liver abscess without biliary disease, often with multiorgan metastatic infection. It can cause severe critical illness with significant morbidity and disability. There remains limited literature and understanding of this syndrome in the United States.</p><p><strong>Objectives: </strong>This article aims to describe the clinical characteristics of hospitalized and critically ill patients with ILAS and providing management considerations for critical care clinicians.</p><p><strong>Main outcomes and measures: </strong>Adult patients admitted to Scripps Health from Janurary 1, 2018 to April 1, 2024 were reviewed. Inclusion criteria required radiographic evidence of a liver abscess and cultures (blood or abscess) positive for <i>K.</i> <i>pneumoniae</i>. Data collected included demographics, symptoms and signs, laboratory and radiologic data, metastatic infection characteristics, treatment, mortality, and morbidity. Patient cases were described, and a narrative review describing clinical, therapeutic, and prognostic characteristics was conducted.</p><p><strong>Results: </strong>Six patients had ILAS. Mean age was 54.8 years, no immunosuppression (defined as underlying malignancy, drug-induced, or chronic infection), 83% had diabetes, 50% were male, and 50% were of Asian ethnicity. Liver abscesses were multilocular (50%), and all had percutaneous catheter drainage. Fifty percent of patients developed distant metastatic infections: emphysematous cystitis, pulmonary septic emboli, complicated parapneumonic pleural effusions, meningitis, ventriculitis, cerebral septic emboli, and endophthalmitis. These patients were younger, male, and had a higher rate of intensive care unit (ICU) admission and mechanical ventilation. Two patients required ICU admission with septic shock, diabetic ketoacidosis, respiratory failure, severe thrombocytopenia, and altered mental status. <i>K</i>. <i>pneumoniae</i> isolates were pansensitive except to ampicillin. There was no in-hospital mortality. The patient with meningitis and ventriculitis had full neurological recovery, and the patient with endophthalmitis had very poor residual visual acuity.</p><p><strong>Conclusions and relevance: </strong>ILAS is an emerging disease that can cause severe critical illness with multiorgan involvement. Early identification of the disease and metastatic infection is essential to provide appropriate treatment. Additionally, ILAS patients require screening for endophthalmitis.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"5579095"},"PeriodicalIF":0.0,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal Cerebral Air Embolism Following Central Venous Catheter Mishandling in a Stroke Patient: A Case Report.","authors":"Lucas Ivan Sebastian Rundblad, Troels Gil Lukassen, Anna Garcia-Alix Grynnerup, Sura Azhar Abdulmunem, Helle Klingenberg Iversen, Anders Sode West","doi":"10.1155/crcc/6367510","DOIUrl":"10.1155/crcc/6367510","url":null,"abstract":"<p><strong>Background: </strong>Air embolism is a rare but potentially fatal complication associated with central venous catheter (CVC) use even several days after placement. Although often asymptomatic, large or rapidly introduced volumes of air can result in severe neurologic and cardiovascular compromise.</p><p><strong>Case presentation: </strong>We report a case of fatal cerebral air embolism in a male stroke patient in his early 60s with a history of diabetes, nephropathy, and peritoneal dialysis. Following ischemic stroke, a CVC was inserted for hemodialysis. Seventeen days after stroke onset, the patient was found unconscious, with seizures and signs of acute neurologic deterioration. The hemodialysis catheter was discovered unplugged and unclamped, suggesting accidental or intentional self-manipulation. Imaging confirmed a massive air embolism in both arterial and venous cerebral circulations. Despite immediate intervention, the patient remained unconscious and died 5 days later. Autopsy confirmed the diagnosis and excluded cardiac or pulmonary shunts.</p><p><strong>Conclusion: </strong>This case highlights the fatal potential of air embolism following CVC mishandling. Prevention requires meticulous catheter management, staff training, and informing patients about risks.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"6367510"},"PeriodicalIF":0.0,"publicationDate":"2026-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13282676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macroscopic Pulmonary Fat Embolism Secondary to Intraosseous Line Placement: A Case Report.","authors":"Stephanie J Chen, Andrew C Sanchez, Serena T Hua, Joel N Murala, Charisma J Kaushik, Amit Banga, Gundeep S Dhillon","doi":"10.1155/crcc/7302079","DOIUrl":"10.1155/crcc/7302079","url":null,"abstract":"<p><strong>Background: </strong>Intraosseous access is commonly used for vascular access in emergent settings. It is generally thought to be well tolerated with minimal complications. We report the first case of clinically significant macroscopic pulmonary fat embolism secondary to intraosseous access.</p><p><strong>Case presentation: </strong>A 67-year-old woman developed profound hypotension and severe biventricular dysfunction shortly after intraosseous access and resuscitation. She required emergent venoarterial extracorporeal membrane oxygenation and Impella for cardiopulmonary support. Computed tomography revealed a new macroscopic pulmonary fat embolism compared with prior imaging 1 day prior. Aspiration thrombectomy was successfully performed with significant improvement in hemodynamics. Unfortunately, she suffered an anoxic brain injury during resuscitation and was ultimately transitioned to comfort care.</p><p><strong>Conclusions: </strong>Although intraosseous access is often considered a safe procedure, this case highlights the need for awareness of this rare but serious and potentially lethal complication. Treatment of pulmonary fat embolism is often supportive; however, aspiration thrombectomy has a potential therapeutic role in macroscopic cases.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"7302079"},"PeriodicalIF":0.0,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13247423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heat Stroke Encephalopathy Without the Presence of Distinct Imaging Findings: Case Report and Review of Literature.","authors":"Ryan Sholes, David J Walz, Julia Evans, Tessa Connelly, Joseph Rigotti","doi":"10.1155/crcc/6609879","DOIUrl":"10.1155/crcc/6609879","url":null,"abstract":"<p><p>Heat stroke is a life-threatening emergency characterized by severe hyperthermia and acute central nervous system (CNS) dysfunction. We describe a 72-year-old man who was found unresponsive in his vehicle on a day with ambient temperatures exceeding 90°F. On arrival, his core temperature was 105.8°F, and Glasgow Coma Scale (GCS) score was 5. Despite prompt initiation of active cooling and supportive care with normalization of body temperature, the patient developed persistent and fluctuating encephalopathy. Extensive metabolic, infectious, and toxicologic evaluations were unrevealing. Thyroid-stimulating hormone was normal, arterial blood gases showed no acid-base derangements, ammonia and liver function tests were within normal limits, and urine toxicology was negative. Electroencephalography demonstrated diffuse cerebral slowing without epileptiform activity. Brain MRI performed approximately 1 week after admission under anesthesia, including diffusion-weighted imaging, showed no acute abnormalities, revealing only mild age-related atrophy and chronic small-vessel ischemic changes. The patient's neurologic function failed to recover over a prolonged hospitalization, and he ultimately died following transition to comfort-focused care on hospital Day 27. This case highlights that severe and persistent encephalopathy may occur in the setting of probable heat stroke despite unrevealing conventional neuroimaging and underscores the diagnostic uncertainty and limitations of MRI in evaluating heat-related neurologic injury.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"6609879"},"PeriodicalIF":0.0,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13243764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148213189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Heparin-Induced Thrombocytopenia in the Setting of Venoarterial Extracorporeal Membrane Oxygenation as a Bridge to Orthotopic Heart Transplant.","authors":"Ethan J Han, Nicholas Kalekas, Matthew S Vandiver","doi":"10.1155/crcc/5510861","DOIUrl":"10.1155/crcc/5510861","url":null,"abstract":"<p><p>Heparin-induced thrombocytopenia (HIT) is a highly impactful prothrombotic condition produced by antibody formation after heparin administration, which leads to platelet activation and both thrombocytopenia and paradoxical thrombosis. HIT has a relatively high mortality rate and greatly complicates anticoagulation strategy in patients requiring surgeries necessitating cardiopulmonary bypass, such as orthotopic heart transplant (OHT). Here, we present a small case report involving two patients who developed HIT in the setting of ongoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for cardiogenic shock while being listed for OHT and the novel plasma exchange strategy that was utilized to manage their HIT through the transplant process.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"5510861"},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148058286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Stellate Ganglion Block After Ventricular Arrhythmia May Hide Clinical Signs of the Cushing Triad: A Case Study and Review of the Literature.","authors":"Michael Watchi, Victor Penaud, Valentina Ditali, Fabio Silvio Taccone","doi":"10.1155/crcc/6360234","DOIUrl":"10.1155/crcc/6360234","url":null,"abstract":"<p><strong>Background: </strong>Stellate ganglion blockade (SGB) has been described as a rescue therapy in recurrent electrical storm, with very few reported complications, except local hematomas. Yet the proximity of major blood vessels and the risk of a sympathetic reaction could expose patients to additional adverse events.</p><p><strong>Case report: </strong>We reported the case of a 34-year-old patient, in whom a bilateral SGB was performed after in-hospital cardiac arrest due to recurrent polymorphic ventricular tachycardia. She developed bilateral areflexic mydriasis, diffuse cerebral edema, pneumocephalus, and brainstem herniation and ultimately died from acute intracranial hypertension. We suspected that bilateral SGB, with its most frequent known complications, Horner's syndrome, might have hidden neurological worsening by blunting some clinical signs, which resulted in delayed diagnosis of intracranial hypertension and brain swelling.</p><p><strong>Conclusions: </strong>The blocking of sympathetic efferences of the stellate ganglion may result in transient effects that interfere with neurological examination, especially when performed bilaterally.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"6360234"},"PeriodicalIF":0.0,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13202304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autopsy-Confirmed CMV Adrenalitis With Bilateral Adrenal Hemorrhage Following Presumed Critical Illness-Related Corticosteroid Insufficiency During Prolonged ICU Stay: A Case Report.","authors":"Yoko Kanamitsu, Yusuke Seino, Natsumi Toyoda, Yoshiya Sugiura, Tomonori Takano, Hiroyuki Kunishima, Yukio Sato, Masaki Izumo, Shigeki Fujitani","doi":"10.1155/crcc/6331364","DOIUrl":"10.1155/crcc/6331364","url":null,"abstract":"<p><strong>Background: </strong>In critically ill patients, critical illness-related corticosteroid insufficiency (CIRCI) is an important cause of vasopressor-refractory shock. However, distinguishing relative or functional CIRCI from structural adrenal insufficiency-such as that caused by hemorrhagic adrenal necrosis-can be challenging because their clinical presentations often overlap despite fundamentally different pathophysiological mechanisms. Cytomegalovirus (CMV) adrenalitis with hemorrhagic adrenal necrosis is rare, potentially fatal, and may be overlooked.</p><p><strong>Case presentation: </strong>A 70-year-old man with ischemic cardiomyopathy and diabetic nephropathy-related chronic kidney disease, without known immunodeficiency, was admitted for acute decompensated right-sided heart failure. He required intensive care and continuous renal replacement therapy for refractory right-sided heart failure and renal failure. During his ICU stay, he experienced two episodes of vasopressor-refractory shock. Although the random serum cortisol level was not unequivocally low, hydrocortisone was administered for clinically presumed CIRCI, resulting in transient hemodynamic improvement. After tapering and discontinuation of hydrocortisone, shock recurred and progressed despite treatment for presumed septic shock, and the patient died. Autopsy revealed extensive bilateral hemorrhagic adrenal necrosis. Microscopic examination demonstrated characteristic \"owl's eye\" intranuclear inclusions and positive CMV immunohistochemistry, consistent with CMV adrenalitis causing acute structural adrenal failure.</p><p><strong>Conclusion: </strong>Even in critically ill patients without apparent baseline immunodeficiency, secondary immunosuppression due to prolonged ICU care may facilitate CMV reactivation, leading to fatal adrenal insufficiency. This case highlights the importance of distinguishing presumed CIRCI from evolving structural adrenal failure and of considering CMV adrenalitis in prolonged ICU patients with recurrent shock.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"6331364"},"PeriodicalIF":0.0,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13199853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of an Autism Spectrum Disorder (ASD) Patient With Respiratory Failure in the Intensive Care Unit: A Case Report on the Role of Dexmedetomidine.","authors":"Alessandra Ciccozzi, Federico Murgia, Alba Piroli, Antonella Paladini, Claudia Ciccone, Francesca Leonardis, Davide Fionda, Antonello Ciccone, Franco Marinangeli","doi":"10.1155/crcc/2549155","DOIUrl":"10.1155/crcc/2549155","url":null,"abstract":"<p><p>This clinical case describes the management, in an intensive care unit (ICU), of a patient with a severe form of autism spectrum disorder (ASD) Level 3, suffering from acute respiratory failure that evolved into acute respiratory distress syndrome (ARDS). Throughout the entire period of hospitalisation in the ICU, sedation of the patient played a key role in the performance of all invasive and noninvasive therapeutic procedures, in particular artificial ventilation and subsequent weaning, due to the underlying disorder that rendered the patient completely uncooperative. Dexmedetomidine was used during initial admission to the ICU for initial treatment, during the period of artificial ventilation and finally during weaning from mechanical ventilation. The <i>α</i> ₂ agonist, due to its pharmacodynamic and pharmacokinetic characteristics, also facilitated the overlap with home antipsychotic drugs upon both discontinuation and reinstatement, allowing discharge from the ICU and safe and serene home management of the tracheostomy until its closure.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"2549155"},"PeriodicalIF":0.0,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147989951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Serotonin Syndrome Associated With Acute Quetiapine Poisoning.","authors":"Dan Wu, Haidong Qin","doi":"10.1155/crcc/5831415","DOIUrl":"10.1155/crcc/5831415","url":null,"abstract":"<p><p>A 21-year-old woman was admitted to our emergency department following a 3-h loss of consciousness after intentional ingestion of multiple psychotropic medications. Initial management included gastric lavage, catharsis, intravenous fluid resuscitation, diuresis, and hemoperfusion to enhance toxin elimination. Shortly after admission, she developed rapid respiratory deterioration, high fever, limb tremors, and tachycardia. Emergency endotracheal intubation and mechanical ventilation were initiated, along with sedation and active cooling measures. A comprehensive workup-including complete blood count, procalcitonin (PCT), blood, urine, and sputum cultures, and chest CT-was performed to exclude infectious etiologies. After ruling out other potential causes, a diagnosis of serotonin syndrome was related to quetiapine fumarate overdose. With aggressive supportive care and enhanced drug clearance, the patient gradually regained consciousness, achieved hemodynamic stability, and was successfully weaned from mechanical ventilation before being discharged without neurological sequelae. Clinicians should maintain a high index of suspicion for serotonin syndrome in patients with quetiapine overdose who present with altered mental status, autonomic instability, hyperthermia, and neuromuscular abnormalities. Early recognition and prompt symptomatic intervention are critical to improving clinical outcomes.</p>","PeriodicalId":52357,"journal":{"name":"Case Reports in Critical Care","volume":"2026 ","pages":"5831415"},"PeriodicalIF":0.0,"publicationDate":"2026-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13185752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147984020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}