Equity neuroscience最新文献

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Introduction: A SEQUINS inductee recalls taking aim at inequities. 简介:一个亮片入选者回忆瞄准不公平。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-07-08 DOI: 10.1016/j.neuros.2026.100064
Robert J Adams
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引用次数: 0
Patient navigation in neuro-oncology: A scoping review of programs supporting patients with CNS tumors. 神经肿瘤学中的患者导航:对支持中枢神经系统肿瘤患者的项目进行范围审查。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-08-24 DOI: 10.1016/j.neuros.2026.100067
Steven Shafeek, Kevin Placide, Cleopatra Elshiekh, Anna Druker, Liana Wu, Antonuos Ishak, Johanna Goldberg, Francesca M Gany, Joshua A Budhu
{"title":"Patient navigation in neuro-oncology: A scoping review of programs supporting patients with CNS tumors.","authors":"Steven Shafeek, Kevin Placide, Cleopatra Elshiekh, Anna Druker, Liana Wu, Antonuos Ishak, Johanna Goldberg, Francesca M Gany, Joshua A Budhu","doi":"10.1016/j.neuros.2026.100067","DOIUrl":"10.1016/j.neuros.2026.100067","url":null,"abstract":"<p><strong>Purpose of review: </strong>Patients with primary central nervous system (CNS) tumors and brain metastases face substantial barriers across the cancer care continuum, including cognitive impairment, complex care transitions, psychosocial distress, and financial hardship. Patient navigation programs aim to support patients and caregivers by facilitating access to services and coordinating care, yet their role in neuro-oncology remains poorly characterized. This scoping review examines the structure, delivery, and reported outcomes of patient navigation programs for individuals with CNS tumors.</p><p><strong>Methods: </strong>We conducted a comprehensive literature search of Medline, Embase, PsycINFO, and Cochrane Central to identify studies published from 1990 onward describing patient navigation interventions for adults with primary CNS tumors or brain metastases. Data were extracted on study design, intervention focus, navigator role, delivery modality, population characteristics, and reported outcomes.</p><p><strong>Recent findings: </strong>Twenty-two studies met inclusion criteria, including 15 conference abstracts and 7 peer-reviewed journal articles. Navigation programs varied in structure but commonly addressed care coordination, patient education, emotional support, financial navigation, and access to clinical trials. Services were delivered in person, by telephone, or through hybrid models. Navigators included nurses, social workers, clinical trial coordinators, and non-clinical staff. Reported outcomes included improved care transitions, increased patient satisfaction, enhanced emotional well-being, reduced emergency department utilization, and, in some programs, reduced financial burden and increased clinical trial enrollment. Barriers included cognitive limitations, challenges in outcome measurement, and inconsistent documentation.</p><p><strong>Summary: </strong>Patient navigation programs in neuro-oncology show promise in addressing complex patient needs, but additional high-quality outcomes data are needed to inform future implementation.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 3","pages":"100067"},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148922626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stroke in people living with HIV and 6-month outcomes in Northwestern Tanzania. 坦桑尼亚西北部艾滋病毒感染者中风和6个月预后。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-07-08 DOI: 10.1016/j.neuros.2026.100063
Lilian Andrew Mwamba, Emmanuel M Bukelebe, Innocent Kitandu Paul, Joshua Ngimbwa, Matilda K Basinda, Benjamin Andrew, Amon B Paul, Akili Mawazo, Dorice Lucas, Ladius Rudovick, Bahati Wajanga, Samuel Kalluvya, Paul Olowoyo, Robert Peck, Sarah Shali Matuja
{"title":"Stroke in people living with HIV and 6-month outcomes in Northwestern Tanzania.","authors":"Lilian Andrew Mwamba, Emmanuel M Bukelebe, Innocent Kitandu Paul, Joshua Ngimbwa, Matilda K Basinda, Benjamin Andrew, Amon B Paul, Akili Mawazo, Dorice Lucas, Ladius Rudovick, Bahati Wajanga, Samuel Kalluvya, Paul Olowoyo, Robert Peck, Sarah Shali Matuja","doi":"10.1016/j.neuros.2026.100063","DOIUrl":"10.1016/j.neuros.2026.100063","url":null,"abstract":"<p><strong>Introduction: </strong>Stroke in HIV presents with distinct characteristics and varying post-stroke recovery patterns, particularly in the antiretroviral therapy (ART) era. We aimed to evaluate the current trends, characteristics, and 6-month outcomes among people living with HIV (PLWH) compared to people without HIV (PWOH).</p><p><strong>Methods: </strong>This prospective cohort study included adults with stroke registered in the Lake Zone Stroke Registry at Bugando Medical Center between November 2023 and March 2025. Baseline characteristics, stroke severity, and outcomes were assessed using the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS), respectively. The Kaplan-Meier analysis was used to describe survival, and the Cox regression model to determine predictors of mortality.</p><p><strong>Results: </strong>We analyzed 295 adults, with an HIV proportion of 8.8% (95% CI: 5.9%-12.7%) (26/295). The median age for the overall study cohort was 66 years (IQR 53.0-77.0), and 55.9% (165/295) were males. Among PLWH, the median age was 53.5 years (IQR 44.3-67.0), females were 61.5% (16/26), and the majority had hypertension, 57.6% (15/26). The median CD4 count was 518 cells/μl (IQR 151.5-571), and 84.6% (22/26) were naïve to ART. PLWH experienced a longer hospital stay, 5 IQR (2-7) days. Both groups experienced unfavorable functional outcomes (mRS 3-6), 84.7% (250/295), and a mortality rate of 38.6% (114/295) at 6 months. In the multivariable analysis, dyspnea, presence of leukocytosis, and severe stroke were independent predictors of mortality.</p><p><strong>Conclusion: </strong>Although 6-month outcomes were comparable between both groups, targeted strategies are needed to address healthcare disparities and reduce the additional burden of stroke in PLWH.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148564126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surveillance of medical resources for stroke in rural Japan through the Jichi medical university alumni network. 通过济济医科大学校友网络监测日本农村中风医疗资源。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-06-19 DOI: 10.1016/j.neuros.2026.100062
Takafumi Mashiko, Yuhei Anan, Kosuke Matsuzono, Tadashi Ozawa, Reiji Koide, Ryota Tanaka, Shigeru Fujimoto
{"title":"Surveillance of medical resources for stroke in rural Japan through the Jichi medical university alumni network.","authors":"Takafumi Mashiko, Yuhei Anan, Kosuke Matsuzono, Tadashi Ozawa, Reiji Koide, Ryota Tanaka, Shigeru Fujimoto","doi":"10.1016/j.neuros.2026.100062","DOIUrl":"10.1016/j.neuros.2026.100062","url":null,"abstract":"<p><strong>Background: </strong>Japan's rapidly aging population has made equitable delivery of stroke care a national priority. However, the status of medical resources in remote regions remains unclear.</p><p><strong>Methods: </strong>A questionnaire survey was distributed in 2017-2018 to the Jichi Medical University alumni network, whose members provide medical care in rural communities and outlying islands.</p><p><strong>Results: </strong>A total of 385 responses were received (response rate = 44.8%), and 236 responses from institutes in rural or island regions were analyzed. The median number of physicians per institute was two in rural areas and one on islands, with approximately 80% specializing in general internal medicine. Among 4569 patients with stroke or transient ischemic attack, including 2860 with ischemic stroke, 95 (3.3%) received intravenous tissue plasminogen activator and 27 (0.95%) underwent mechanical thrombectomy. Computed tomography was available in 116 institutes (49.2%), and carotid ultrasonography in 174 (73.7%). Antithrombotic therapy was available in approximately 60% of institutes. Of respondents, 185 of 201 (92.0%) in rural areas and 31 of 32 (96.9%) on islands recognized the need for stroke care education, while 132 (65.7%) and 25 (78.1%), respectively, expressed demand for telestroke support. However, telestroke systems were available in only 36 rural institutes (17.6%) and 13 islands (40.6%).</p><p><strong>Conclusions: </strong>This study reveals the substantial unmet need for stroke care resources in rural and remote settings. While the availability of physicians and imaging devices has partially improved, major challenges remain, including unequal access to reperfusion therapy, limited supply of essential medications, and insufficient telemedicine infrastructure.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148564163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social determinants of health and stroke care and outcomes: SEQUINS lecture 2025. 健康和中风护理和结果的社会决定因素:SEQUINS讲座2025。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-07-04 DOI: 10.1016/j.neuros.2026.100065
Moira K Kapral
{"title":"Social determinants of health and stroke care and outcomes: SEQUINS lecture 2025.","authors":"Moira K Kapral","doi":"10.1016/j.neuros.2026.100065","DOIUrl":"10.1016/j.neuros.2026.100065","url":null,"abstract":"<p><p>The past decades have brought significant advances in stroke care through new therapies and coordinated stroke systems. However, these advances have not been experienced equally across all populations. Social determinants of health, defined as the conditions in which people are born, grow, live, work and age … are associated with variations and inequities in stroke incidence, care processes, and outcomes. This paper provides an overview of the effect of factors such as sex and gender, socioeconomic status, rural residence, race and ethnicity, and immigration status on stroke care and outcomes, highlights structural drivers, and outlines directions for the future.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148612341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Con-sequins 2026: From mission to momentum. 后果序列2026:从使命到动力。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-08-12 DOI: 10.1016/j.neuros.2026.100066
Edwin Akomaning, Carol Joseph, Iris Ovbiagele, Raelle Tagge
{"title":"Con-sequins 2026: From mission to momentum.","authors":"Edwin Akomaning, Carol Joseph, Iris Ovbiagele, Raelle Tagge","doi":"10.1016/j.neuros.2026.100066","DOIUrl":"10.1016/j.neuros.2026.100066","url":null,"abstract":"<p><p>A foundational challenge of equity neuroscience is understanding how to move from describing inequitable neurological disparities to identifying the mechanisms, systems, and infrastructures needed to reduce them. The Society for Equity Neuroscience (SEQUINS) was founded in 2024 to advance brain health equity and reduce neurological disparities through science [1]. CON-Sequins '26, held on May 14, 2026, in Charleston, South Carolina, was the society's second annual meeting and reflected its expanding role as a scientific, educational, disseminative, and workforce-development platform. It convened investigators, clinicians, trainees, public health leaders, and community-engaged scholars from across the United States and beyond. Major scientific themes included social drivers of Alzheimer's disease and related dementias, upstream contributors to racial disparities in stroke, global neurology, cerebral malaria, global health security, translational science infrastructure, artificial intelligence, clinical trial representation, community-engaged research, and workforce development. Early career scholars presented their work in three distinct poster sessions. This proceedings report summarizes the conference program, emerging scholarship, workforce-development activities, dissemination efforts, participation metrics, and future priorities for the field. Con-Sequins '26 suggests that recurring convenings may provide a key mechanism for translating equity neuroscience from a conceptual framework into research, implementation, mentorship, and policy objectives.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 3","pages":"100066"},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13580621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Counting what counts: Time for an annual statistical update on neurologic health equity. 计算什么是重要的:是时候对神经健康公平进行年度统计更新了。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-09-13 DOI: 10.1016/j.neuros.2026.100071
Bruce Ovbiagele
{"title":"Counting what counts: Time for an annual statistical update on neurologic health equity.","authors":"Bruce Ovbiagele","doi":"10.1016/j.neuros.2026.100071","DOIUrl":"10.1016/j.neuros.2026.100071","url":null,"abstract":"<p><strong>Background: </strong>Neurologic diseases are among the leading causes of death and disability in the United States, yet the magnitude, distribution, and trajectory of neurologic disparities remain difficult to monitor across diseases and populations.</p><p><strong>Opportunity: </strong>Other fields have established powerful recurring statistical resources that have become essential references for clinicians, researchers, policymakers, and the public. For instance, the American Heart Association has produced an annual <i>Heart Disease and Stroke Statistics Update</i> for decades, integrating contemporary data on disease burden, risk factors, outcomes, disparities, and economic costs. Comparable models exist for cancer (American Cancer Society Cancer Statistics) and kidney disease (US Renal Data System Annual Data Report). These models demonstrate the value of a recognizable, authoritative statistical report that is updated as new evidence emerges.</p><p><strong>Proposal: </strong>This Viewpoint proposes an annual U.S. Neurologic Equity Annual Report (NEAR), modeled directly on these precedents, outlines its scope, candidate federal and private data sources, and strategic partnerships. NEAR would synthesize the most recent nationally representative data on incidence, prevalence, mortality, disability-adjusted life years, risk factors, health-care utilization, access and quality of care, and economic costs. Whenever data permit, estimates will be stratified by race/ethnicity, sex/gender, age, and socioeconomic characteristics.</p><p><strong>Conclusion: </strong>Neurology needs a recurring statistical framework that makes inequities measurable, comparable, and visible from year to year. NEAR would provide a common evidence base for identifying populations at greatest risk, tracking whether disparities are widening or narrowing, prioritizing research and prevention, guiding equitable allocation of resources, and evaluating progress toward neurologic health equity.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 3","pages":"100071"},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13645394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge on hypertension among hypertensive stroke survivors in Ghana: A cross-sectional, multicenter study. 加纳高血压中风幸存者的高血压知识:一项横断面、多中心研究。
Equity neuroscience Pub Date : 2026-12-01 Epub Date: 2026-06-22 DOI: 10.1016/j.neuros.2026.100060
Rexford Adu Gyamfi, Albert Akpalu, Ansumana Bockarie, Priscilla Abrafi Opare-Addo, Nana Kwame Ayisi-Boateng, Douglas Anning Opoku, Jude Domfeh Darkwah, Emmanuel Konadu, Agnes Arthur, Kwadwo Agyenim-Boateng, Christiana Neizer, Timothy Fiattor, Nyantakyi Adu-Darko, Nathaniel Adusei Mensah, Raelle Tagge, Michael Ampofo, Hilda Kwapong, John Akassi, John Humphrey Amuasi, Samuel Blay Nguah, Bruce Ovbiagele, Fred Stephen Sarfo
{"title":"Knowledge on hypertension among hypertensive stroke survivors in Ghana: A cross-sectional, multicenter study.","authors":"Rexford Adu Gyamfi, Albert Akpalu, Ansumana Bockarie, Priscilla Abrafi Opare-Addo, Nana Kwame Ayisi-Boateng, Douglas Anning Opoku, Jude Domfeh Darkwah, Emmanuel Konadu, Agnes Arthur, Kwadwo Agyenim-Boateng, Christiana Neizer, Timothy Fiattor, Nyantakyi Adu-Darko, Nathaniel Adusei Mensah, Raelle Tagge, Michael Ampofo, Hilda Kwapong, John Akassi, John Humphrey Amuasi, Samuel Blay Nguah, Bruce Ovbiagele, Fred Stephen Sarfo","doi":"10.1016/j.neuros.2026.100060","DOIUrl":"10.1016/j.neuros.2026.100060","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a premier risk factor for index and recurrent strokes globally. However, knowledge of hypertension as a risk factor for stroke occurrence and subsequent adverse vascular events among recent stroke survivors in the sub-Saharan Africa is limited.</p><p><strong>Purpose: </strong>To assess the level and determinants of knowledge on hypertension and risk of stroke among recent stroke survivors in Ghana.</p><p><strong>Methods: </strong>This is a cross-sectional survey conducted at enrollment of participants involved in the multi-center, phase III randomized trial titled Phone-based Intervention under Nurse Guidance after stroke II (PINGS-2) study. Recent stroke survivors within 1-2 months of stroke onset were recruited from 10 Ghanaian hospitals comprising of (five primary-level, two secondary-level, and three tertiary-level facilities) between 2020 and 2022. We assessed knowledge of hypertension and stroke using a validated 14-item questionnaire on hypertension and stroke. We analyzed data using univariate and multivariate analysis to determine the associations between sociodemographic variables and the knowledge on hypertension among recent stroke survivors.</p><p><strong>Results: </strong>We enrolled 500 participants, mean (SD) age of 58 (12) years, 56.2% being males and 73.3% had ischemic stroke. Out of 14 questions, the mean (SD) score was 8 (3) with a range of 0 to 13. Four factors significantly associated with knowledge of hypertension with adjusted <i>β</i> (95%CI) were Islam religion -1.40 (-2.40 - -0.49), NIHSS score -0.15 (- 0.22 - -0.07) for each unit increase and body mass index 0.08 (0.03 - 0.13) for each kg/m<sup>2</sup> increase and educational attainment with primary level, secondary, and tertiary educational level 1.10 (0.02 - 2.10), 1.60 (0.52 - 2.70), 2.40 (1.20 - 3.60) compared with no education.</p><p><strong>Conclusion: </strong>We found substantial deficiencies in the knowledge on hypertension among recent hypertensive stroke survivors in the Ghanaian population in this multicenter study. Educational interventions are urgently needed to address these knowledge gaps to minimize risk of adverse outcomes among stroke survivors in resource-limited settings.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life indicators among recent Ghanaian stroke survivors across 10 hospitals: A cross-sectional study. 加纳最近10家医院中风幸存者的生活质量指标:一项横断面研究
Equity neuroscience Pub Date : 2026-09-01 Epub Date: 2026-03-26 DOI: 10.1016/j.neuros.2026.100026
Nana Kwame Ayisi-Boateng, Douglas Aninng Opoku, Jude Domfeh Darkwah, Albert Akpalu, Ansumana Bockarie, Emmanuel Konadu, Rexford Adu-Gyamfi, Agnes Arthur, Kwadwo Agyenim-Boateng, Christiana Neizer, Timothy Fiattor, Priscilla Opare-Addo, Nyantakyi Adu-Darko, Nathaniel Adusei-Mensah, Raelle Tagge, Michael Ampofo, Hilda Kwapong, John Akassi, John Humphrey Amuasi, Samuel Blay Nguah, Bruce Ovbiagele, Fred Stephen Sarfo
{"title":"Quality of life indicators among recent Ghanaian stroke survivors across 10 hospitals: A cross-sectional study.","authors":"Nana Kwame Ayisi-Boateng, Douglas Aninng Opoku, Jude Domfeh Darkwah, Albert Akpalu, Ansumana Bockarie, Emmanuel Konadu, Rexford Adu-Gyamfi, Agnes Arthur, Kwadwo Agyenim-Boateng, Christiana Neizer, Timothy Fiattor, Priscilla Opare-Addo, Nyantakyi Adu-Darko, Nathaniel Adusei-Mensah, Raelle Tagge, Michael Ampofo, Hilda Kwapong, John Akassi, John Humphrey Amuasi, Samuel Blay Nguah, Bruce Ovbiagele, Fred Stephen Sarfo","doi":"10.1016/j.neuros.2026.100026","DOIUrl":"10.1016/j.neuros.2026.100026","url":null,"abstract":"<p><strong>Background: </strong>Despite the increased burden of stroke in sub-Saharan Africa, studies assessing patient-centered outcomes such as quality of life (QoL) in the population are limited. We sought to assess the QoL, compare domain scores by sex, as well as their determinants among recent stroke survivors in Ghana.</p><p><strong>Methods: </strong>This multi-centre cross-sectional study was conducted in 10 health facilities in Ghana. We used the European Quality of Life Scale-5 Dimensions (EQ-5D) to assess the QoL among 500 individuals who had survived a stroke within one month of symptom onset and had uncontrolled hypertension. Factors significantly associated with QoL were assessed using multivariable linear regression.</p><p><strong>Results: </strong>The mean age of males was 58.0 (±11.0) vs 59.0 (±12.0) years among the females. Usual activity (1.9 ± 0.7) and mobility (1.8 ± 0.7) had the highest mean scores for perceived problems, whereas anxiety/depression (1.4 ± 0.6) had the lowest. Over half (56.1%) of the stroke survivors rated their EQ-VAS score at or above the median. After adjusting for significant covariates in the multivariate linear regression analysis, female sex (<i>β</i>: 8.90, 95%CI: 4.30, 14.00), living in urban areas (<i>β</i>: 13.00, 95%CI: 5.10, 21.00), having a monthly income of 251 - 500 USD (<i>β</i>: 7.50, 95%CI: 1.80, 13.00) and having higher Barthel index (<i>β</i>: 0.21, 95%CI: 0.13, 0.29) were significantly associated with better QoL (EQ-VAS score). In sex-stratified analyses, male participants living in semi-urban or urban areas, with higher income, and with a higher Barthel index were significantly associated with better QoL. Among female participants, having an untyped stroke type was associated with lower QoL, whereas a higher Barthel index was associated with better QoL.</p><p><strong>Conclusion: </strong>Functional independence, sociodemographic factors, and sex affect the QoL of this cohort of recent stroke survivors with uncontrolled hypertension in Ghana. Living in urban areas, higher functional independence, female sex, and higher income were associated with better QoL. In contrast, having an untyped CT scan was associated with lower QoL among women. Socioeconomic factors and prior health problems in recent stroke survivors significantly influence QoL. Post-stroke QoL may be enhanced by strategies that improve functional recovery and address the social determinants of health.</p>","PeriodicalId":520832,"journal":{"name":"Equity neuroscience","volume":"2 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13177183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147966963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The SEQUINS scholars program: a longitudinal curriculum to advance brain health equity education among early career trainees. SEQUINS学者计划:在早期职业受训者中推进大脑健康公平教育的纵向课程。
Equity neuroscience Pub Date : 2026-09-01 Epub Date: 2026-04-24 DOI: 10.1016/j.neuros.2026.100052
Rachel Forman, Gitanjali Das, Jeremey Ader, Stephanie Lyden, Raelle Tagge, Bruce Ovbiagele, Imama A Naqvi
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