Massy Mutumba, Fred M Ssewamala, Proscovia Nabunya, Francis Matovu, Phionah Namatovu, Jennifer Nattabi
{"title":"Stigma, Mental Health, and HIV Adherence: A Cross-sectional Structural Equation Modeling Study Exploring Direct and Indirect Effects Among School-Engaged Ugandan Adolescents Living With HIV.","authors":"Massy Mutumba, Fred M Ssewamala, Proscovia Nabunya, Francis Matovu, Phionah Namatovu, Jennifer Nattabi","doi":"10.1097/JNC.0000000000000645","DOIUrl":"10.1097/JNC.0000000000000645","url":null,"abstract":"<p><strong>Abstract: </strong>Our study examined how multiple dimensions of HIV-related stigma affect mental health and antiretroviral therapy (ART) adherence among school-engaged adolescents living with HIV in Uganda. Using structural equation modeling with 833 participants recruited from 42 HIV clinics, we examined multiple dimensions of internalized and externalized HIV stigma, and their associations with adherence outcomes. We found that internalized shame and family-based stigma were significantly associated with poor mental health which, in turn, strongly predicted nonadherence to ART. Mediation analyses confirmed indirect pathways from family-based stigma and internalized shame to ART nonadherence via poor mental health. Disclosure stigma was unexpectedly associated with better ART adherence, suggesting possible benefits of selective self-disclosure. However, school-based stigma was not associated with mental health or ART adherence, possibly because of nondisclosure within school settings. Findings underscore the need for multilevel stigma reduction interventions that address internalized and family-level stigma to support ART adherence among school-engaged adolescents living with HIV.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":"434-446"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147826334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shey Thorn, Kimberly June Skeete, Roque Anthony F Velasco
{"title":"Bridges Over Borders: What It Means to Lead, Connect, and Care Right Now.","authors":"Shey Thorn, Kimberly June Skeete, Roque Anthony F Velasco","doi":"10.1097/JNC.0000000000000663","DOIUrl":"10.1097/JNC.0000000000000663","url":null,"abstract":"","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":"527-528"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148153165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and Psychometric Testing of the HIV Care Adherence Journey Instrument for Persons With HIV in the Philippines: A Methodological Study.","authors":"Ryan Q De Torres, Maylin Palatino, Don Operario","doi":"10.1097/JNC.0000000000000565","DOIUrl":"10.1097/JNC.0000000000000565","url":null,"abstract":"<p><strong>Abstract: </strong>The HIV care adherence journey is a dynamic, complex phenomenon that represents more than counting the pills and clinic visits attended. Our study described the development and preliminary psychometric properties of a self-reported measure on the care adherence journey of persons with HIV (PWH). The Polit and Beck approach to measure development was used. A 36-item instrument was initially created and underwent two rounds of expert panel review. Psychometric testing was done with 302 PWH. The best-fitting model had a root-mean-square error of approximation of 0.088, a comparative fit index of 0.898, and a Tucker-Lewis index of 0.882. This model consisted of 7-factor structures and 27 items. The overall Cronbach's alpha of the instrument was 0.94. The HIV Care Adherence Journey Instrument is a culturally appropriate, valid, and reliable tool to assess PWH's experiences with their care adherence journey to promote patient-centered care.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":"422-433"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rogéria Moreira de Abrantes, Fernanda Belmiro de Andrade, Luzia Cibele de Souza Maximiano, Vanessa Carla do Nascimento Gomes Brito, Jocellem Alves de Medeiros, Raíssa Martins de Andrade, Elanna Nayele de Freitas Costa, Alexsandra Rodrigues Feijão
{"title":"Serious Games for HIV Prevention Among Adolescents in a Global Context: A Scoping Review.","authors":"Rogéria Moreira de Abrantes, Fernanda Belmiro de Andrade, Luzia Cibele de Souza Maximiano, Vanessa Carla do Nascimento Gomes Brito, Jocellem Alves de Medeiros, Raíssa Martins de Andrade, Elanna Nayele de Freitas Costa, Alexsandra Rodrigues Feijão","doi":"10.1097/JNC.0000000000000669","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000669","url":null,"abstract":"<p><strong>Abstract: </strong>Adolescents constitute a vulnerable group in the context of HIV because of early sexual debut and engagement in risk behaviors. Traditional health education methods face significant challenges regarding their effectiveness in altering risk perception and promoting sustainable behavioral changes among youth. In this scenario, serious games (SG)-educational technologies that integrate game mechanics for pedagogical and therapeutic purposes, moving beyond pure entertainment-emerge as an approach for HIV prevention. Our study sought to answer the following: What are the types and themes of SGs produced for the prevention of HIV transmission among adolescents? Thus, the objective of this scoping review was to map the types and themes of these games developed for this purpose in the literature. This scoping review, conducted between June and August 2024, was guided by the Joanna Briggs Institute methodology and reported in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews guidelines. Thirteen databases were searched. The 21 selected studies identified four types of SG (video games, mobile applications, card games, and board games), addressing five central themes (HIV testing, prevention, risk behaviors, affective relationships, and sexual and reproductive health). The digital format predominated (87.5%), specifically for computers (47.6%) and smartphones (38%). Serious games are effective in HIV prevention among adolescents by surpassing conventional health education methods through immersion and empowerment. They reinforce the need for combination prevention by integrating gaming into health promotion strategies to reduce vulnerability.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148311289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas Velasquez, Cecília Tomori, Erin M Spaulding
{"title":"Equity in U.S. Solid Organ Transplantation for People Living With HIV: An Integrative Review of Barriers, Policies, and Interventions.","authors":"Nicholas Velasquez, Cecília Tomori, Erin M Spaulding","doi":"10.1097/JNC.0000000000000648","DOIUrl":"10.1097/JNC.0000000000000648","url":null,"abstract":"<p><strong>Abstract: </strong>Although survival for people living with HIV (PLWH) has improved, their need for solid organ transplantation (SOT) is disproportionate. Equitable access remains limited despite the HIV Organ Policy Equity (HOPE) Act, a U.S. federal law enacted in 2013 permitting transplantation from donors with HIV to recipients with HIV under research protocols. This integrative review (PubMed, Embase, CINAHL; 2011-2024) synthesized U.S. studies examining barriers, interventions, and policies affecting access to SOT for PLWH, organized using the Social Ecological Model. Thirty studies met inclusion criteria, with most focused on kidney and liver transplantation with limited evidence for thoracic transplantation. Barriers occurred across individual (stigma, knowledge gaps), organizational (restrictive eligibility), and structural or policy levels (insurance barriers, geographic inequities). Few studies evaluated interventions. Studies evaluating HOPE Act implementation demonstrated reduced wait times and increased transplantation, particularly among Black and publicly insured candidates. Priorities include center accountability and removing research-only barriers to thoracic D+/R+ transplantation.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148267956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiangming Zhan, Meijia Song, Chad E Forbes, Jun Chen, Hongzhou Lu, Angel B Algarin
{"title":"Biopsychosocial Determinants of Frailty in Older People Living With HIV in China: A Bayesian Network Analysis.","authors":"Xiangming Zhan, Meijia Song, Chad E Forbes, Jun Chen, Hongzhou Lu, Angel B Algarin","doi":"10.1097/JNC.0000000000000667","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000667","url":null,"abstract":"<p><strong>Abstract: </strong>People living with HIV (PWH) experience accelerated aging and elevated frailty risk, representing the convergence of biological and psychosocial aging processes. We enrolled 665 PWH ages ≥50 years in a multicenter study in China. We examined the intersection of biological factors (e.g., CD4+ T-cell count, comorbidities), psychological factors (i.e., depression, anxiety), and social determinants in frailty development. A Bayesian network model was developed to characterize these complex interactions. Frailty prevalence was 17.1%. The Bayesian network identified depression as a central node connecting immune dysfunction to frailty through a CD4→anxiety→depression pathway. The model achieved robust performance (area under the curve = 0.879). Probability of frailty ranged from 1.4% in individuals aged 50-59 years without risk factors to 74.0% in those ages ≥70 years with depression and multiple comorbidities. This model offers clinicians a practical risk assessment tool for aging PWH and highlights depression as a modifiable target, supporting the integration of mental health screening in HIV geriatric care.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148261354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lessons From a Simulation Study Assessing Social Biases of Generative Artificial Intelligence.","authors":"Yulin Hswen, Thu Nguyen","doi":"10.1097/JNC.0000000000000660","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000660","url":null,"abstract":"","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148255424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas Byron Comninos, Melissa Anne Power, Yvette Victoria Katherine Ormsby, Christos Floratos, David Arthur Lewis, Rohan Indika Bopage
{"title":"Scorecards to Support Cardiovascular Risk Measurement in Older Adults at an Outer Metropolitan Australian Service: A Retrospective Observational Study.","authors":"Nicholas Byron Comninos, Melissa Anne Power, Yvette Victoria Katherine Ormsby, Christos Floratos, David Arthur Lewis, Rohan Indika Bopage","doi":"10.1097/JNC.0000000000000658","DOIUrl":"10.1097/JNC.0000000000000658","url":null,"abstract":"<p><strong>Abstract: </strong>Our study aimed to assess cardiovascular risk factor measurements (CVRFM) among people ages ≥40 years attending a sexual health clinic for HIV care before, during, and after scorecard implementation. Scorecards were 1-page visual summaries of risk factor measurement metrics distributed among clinic staff quarterly between November 1, 2022, and October 31, 2023. The median number of yearly risk-factor measurements increased from one in the year before scorecards to three in the year after scorecards. Measurements of systolic blood pressure, total cholesterol:high-density lipoprotein ratio, and glycated hemoglobin increased during the time period; smoking status measurements remained unchanged. Complete risk factor measurements (all four measurements in 1 year) increased from 11% before scorecards to 36% after scorecards. Weight/body mass index measurements and general practitioner linkage increased; having these were also associated with a higher number of other CVRFMs. As a quality-improvement initiative, scorecards may support clinic processes for CVRFM. Further interventions to improve measurement and reduce risk, potentially through sexual health clinic and general practitioner shared care, should be explored.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148221637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zainab Al Tameemi, Stephanie A Ruderman, Kristina A Crothers, Bridget M Whitney, Joseph A Delaney, Heidi M Crane, Vishesh K Kapur
{"title":"Factors Associated With Completing Sleep Studies Among People With HIV Receiving Care at a United States HIV Clinic: A Descriptive Study.","authors":"Zainab Al Tameemi, Stephanie A Ruderman, Kristina A Crothers, Bridget M Whitney, Joseph A Delaney, Heidi M Crane, Vishesh K Kapur","doi":"10.1097/JNC.0000000000000665","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000665","url":null,"abstract":"<p><strong>Abstract: </strong>People with HIV (PWH) have a high prevalence of obstructive sleep apnea (OSA), yet the condition receives minimal attention despite a high prevalence of OSA risk factors. PWH attending HIV care between 2008 and 2023 were eligible. Sleep studies were identified in electronic health records. We estimated associations between completion of a study and HIV factors and fatigue using adjusted relative risk regression. Among 3,977 PWH, 4% completed a sleep study. PWH who underwent sleep studies were older (50 vs. 48 years), fewer had low current CD4 cell counts (2% vs. 11% < 200 cells/mm3), and more had HIV viral suppression (97% vs. 85%) than those who did not. Bothersome fatigue was associated with 2.9 times (95% confidence interval: 1.9-4.4) greater likelihood of completing a sleep study. Sleep studies are rarely conducted among PWH. PWH who received a sleep study had better HIV control (higher CD4 count/viral suppression) and a greater burden of fatigue and OSA-related comorbidities.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148221627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khalid W Freij, Shannon G Wilson, Dyan M White-Gilliam, Caroline K Webb, Shameka L Cody, S Justin Thomas, Pariya L Fazeli, Robert E Sorge, Edwin N Aroke, Burel R Goodin
{"title":"Accelerated Pace of Biological Aging in People With HIV and Insomnia Living in Southeastern United States: A Cross-Sectional Study.","authors":"Khalid W Freij, Shannon G Wilson, Dyan M White-Gilliam, Caroline K Webb, Shameka L Cody, S Justin Thomas, Pariya L Fazeli, Robert E Sorge, Edwin N Aroke, Burel R Goodin","doi":"10.1097/JNC.0000000000000666","DOIUrl":"10.1097/JNC.0000000000000666","url":null,"abstract":"<p><strong>Abstract: </strong>Our study examined the relationship between insomnia and the pace of biological aging in persons with HIV (PWH). We used Dunedin Pace of Aging from the Epigenome (DunedinPACE) to determine pace of biological aging in adults, ages 18 to 85 years: 34 without HIV or insomnia, 13 without HIV but with insomnia, 22 with HIV but no insomnia, and 38 with HIV and insomnia. Findings revealed that irrespective of insomnia status, PWH had a greater acceleration of biological aging (DunedinPACE) compared with those without HIV. PWH with insomnia demonstrated many of the highest values for DunedinPACE. This suggests that sleep disruption may act as an additional mechanism compounding immune aging and chronic inflammation already associated with HIV, such that PWH who also experience insomnia face a cumulative burden of risk factors that together drive a faster pace of biological aging.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148221657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}