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The American journal of psychiatry最新文献

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Schizophrenia and Doxycycline: Microbiome Mediator? 多西环素与精神分裂症：微生物组调节剂？
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 DOI: 10.1176/appi.ajp.20251193
Chika Uzoigwe
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引用次数: 0
Cannabis and Psychosis: Association, Subtype, or Separate Disorder? 大麻和精神病：关联，亚型，还是单独的疾病？
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 DOI: 10.1176/appi.ajp.20260508
Brian A Coffman, Alfredo Sklar, Fran López-Caballero
{"title":"Cannabis and Psychosis: Association, Subtype, or Separate Disorder?","authors":"Brian A Coffman, Alfredo Sklar, Fran López-Caballero","doi":"10.1176/appi.ajp.20260508","DOIUrl":"10.1176/appi.ajp.20260508","url":null,"abstract":"","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":"183 8","pages":"514-516"},"PeriodicalIF":14.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148650489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Schizophrenia: Insights Into its Etiology and Pathophysiology. 精神分裂症：对其病因学和病理生理学的见解。
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 DOI: 10.1176/appi.ajp.20260614
Ned H Kalin
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引用次数: 0
Schizophrenia Beyond Genome-Wide Association Studies: It's About Time. 精神分裂症超越全基因组关联研究：是时候了。
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 DOI: 10.1176/appi.ajp.20260566
Giulio Pergola, Daniel R Weinberger
{"title":"Schizophrenia Beyond Genome-Wide Association Studies: It's About Time.","authors":"Giulio Pergola, Daniel R Weinberger","doi":"10.1176/appi.ajp.20260566","DOIUrl":"https://doi.org/10.1176/appi.ajp.20260566","url":null,"abstract":"<p><p>The discovery of potentially many hundreds of risk genes for schizophrenia does not resolve the mystery of the illness at the level of an individual. The diversity of implicated gene functions has encouraged speculation that there are convergent biological pathways that mediate risk at the systems level, perhaps represented in gene coexpression patterns. The authors emphasize that gene coexpression varies across development, with some molecular elements related to schizophrenia risk losing importance or gaining momentum over time. The systems biology of risk and environmental exposures associated with risk are both time-dependent. The authors propose that the dynamic gene-environment interplay subtended by shifting coexpression patterns may explain variable expressivity of genetic risk during development. In particular, gene-environment correlations provide a mechanism for the individual-hence for their genes-to affect the environment and thus individual experience, promoting chains of life events. The authors envision the paired study of molecular and behavioral patterns over time as a way to identify novel treatments and preventive strategies to change the course of schizophrenia.</p>","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":"183 8","pages":"526-539"},"PeriodicalIF":14.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148650430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reporting of Sex Specific Findings Leads to Altered Conclusions Regarding Potential Protective Effects of Doxycycline for Schizophrenia. 关于多西环素对精神分裂症的潜在保护作用，性别特异性发现的报告导致结论的改变。
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 DOI: 10.1176/appi.ajp.20251277
Lot D de Witte, Marijn Laban, Veerle Bergink
{"title":"Reporting of Sex Specific Findings Leads to Altered Conclusions Regarding Potential Protective Effects of Doxycycline for Schizophrenia.","authors":"Lot D de Witte, Marijn Laban, Veerle Bergink","doi":"10.1176/appi.ajp.20251277","DOIUrl":"10.1176/appi.ajp.20251277","url":null,"abstract":"","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":" ","pages":"593"},"PeriodicalIF":14.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Doxycycline, Schizophrenia, and Toxoplasmosis. 强力霉素、精神分裂症和弓形虫病。
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 DOI: 10.1176/appi.ajp.20251231
Kevin J Black
{"title":"Doxycycline, Schizophrenia, and Toxoplasmosis.","authors":"Kevin J Black","doi":"10.1176/appi.ajp.20251231","DOIUrl":"10.1176/appi.ajp.20251231","url":null,"abstract":"","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":" ","pages":"592"},"PeriodicalIF":14.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Proposed Expansion of the Definition of Treatment-Resistant Schizophrenia. 对难治性精神分裂症定义的扩展建议。
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 Epub Date: 2026-06-10 DOI: 10.1176/appi.ajp.20251269
Jose M Rubio, John M Kane
{"title":"A Proposed Expansion of the Definition of Treatment-Resistant Schizophrenia.","authors":"Jose M Rubio, John M Kane","doi":"10.1176/appi.ajp.20251269","DOIUrl":"10.1176/appi.ajp.20251269","url":null,"abstract":"","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":" ","pages":"523-525"},"PeriodicalIF":14.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148214175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copy Number Variation in Schizophrenia: Developmental Timing and Clinical Heterogeneity. 精神分裂症的拷贝数变异：发育时间和临床异质性。
IF 14.7
The American journal of psychiatry Pub Date : 2026-08-01 DOI: 10.1176/appi.ajp.20260449
Rebecca Birnbaum
{"title":"Copy Number Variation in Schizophrenia: Developmental Timing and Clinical Heterogeneity.","authors":"Rebecca Birnbaum","doi":"10.1176/appi.ajp.20260449","DOIUrl":"https://doi.org/10.1176/appi.ajp.20260449","url":null,"abstract":"","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":"183 8","pages":"517-519"},"PeriodicalIF":14.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148650433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDA, CMS, and Digital Therapeutics in Psychiatry: Recommendations in a Novel Frontier. FDA， CMS和精神病学的数字治疗：新前沿的建议。
IF 14.7
The American journal of psychiatry Pub Date : 2026-07-01 DOI: 10.1176/appi.ajp.20250737
John Torous, Iliyan Ivanov, Salvador Guinjoan, Alison Hwong, Margaret Y Yau, Jonathan E Alpert
{"title":"FDA, CMS, and Digital Therapeutics in Psychiatry: Recommendations in a Novel Frontier.","authors":"John Torous, Iliyan Ivanov, Salvador Guinjoan, Alison Hwong, Margaret Y Yau, Jonathan E Alpert","doi":"10.1176/appi.ajp.20250737","DOIUrl":"10.1176/appi.ajp.20250737","url":null,"abstract":"","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":" ","pages":"447-449"},"PeriodicalIF":14.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Represcribing Previously Used Antipsychotics: Response to So. 描述以前使用的抗精神病药物：对So的反应。
IF 14.7
The American journal of psychiatry Pub Date : 2026-07-01 DOI: 10.1176/appi.ajp.20251258
Guorui Zhao, Yaoyao Sun, Yuyanan Zhang, Stefan Leucht, Weihua Yue
{"title":"Represcribing Previously Used Antipsychotics: Response to So.","authors":"Guorui Zhao, Yaoyao Sun, Yuyanan Zhang, Stefan Leucht, Weihua Yue","doi":"10.1176/appi.ajp.20251258","DOIUrl":"https://doi.org/10.1176/appi.ajp.20251258","url":null,"abstract":"","PeriodicalId":520786,"journal":{"name":"The American journal of psychiatry","volume":"183 7","pages":"494-495"},"PeriodicalIF":14.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148364805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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