QJM : monthly journal of the Association of Physicians最新文献_第4页

COVID-19 vaccine-associated optic neuritis. COVID-19疫苗相关视神经炎。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-10-25 DOI: 10.1093/qjmed/hcac208

W-J A Lee

引用次数: 10

Multisystem inflammatory syndrome following COVID-19 vaccination: ignored and underdiagnosed. COVID-19疫苗接种后的多系统炎症综合征:被忽视和诊断不足。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-10-25 DOI: 10.1093/qjmed/hcab292

P Ish, S Kunal

{"title":"Multisystem inflammatory syndrome following COVID-19 vaccination: ignored and underdiagnosed.","authors":"P Ish, S Kunal","doi":"10.1093/qjmed/hcab292","DOIUrl":"https://doi.org/10.1093/qjmed/hcab292","url":null,"abstract":"• The patient in the article by Kono et al. developed fever and malaise post-second dose of COVID-19 vaccination. This was followed by dyspnoea and refractory type I respiratory failure. The investigations reveal raised C-reactive protein and D-dimer levels concordant with MIS. • The computed tomography revealed bilateral ground glass opacities with an apparent cardiomegaly in Figure 1 which shows dramatic recovery in both these findings in Figure 2. An underlying myocarditis only can explain such a rapid and complete reversal. There is no mention of any electrocardiogram and echocardiograph done in the patient which may have helped to narrow down the diagnosis. The patient was also extubated within 2 days of mechanical ventilation, which is unlikely for any interstitial lung disease. • The diagnosis of MIS-V is difficult and often relies on the existing diagnostic criteria for MIS in adults (MIS-A). Dysregulated hyperimmune response has been postulated as a probable underlying mechanism. Cardiac involvement along with mucocutaneous involvement are most commonly involved organs, besides gastrointestinal, musculo-skeletal, pulmonary and renal. The mainstay of treatment is steroids which leads to a rapid response. The patient had myalgia and respiratory failure for which musculoskeletal and cardiac evaluation is essential. Even if there was isolated myocarditis, which has increasingly been reported with messenger RNA vaccines throughout the world, the treatment essentially remains steroids only.","PeriodicalId":520760,"journal":{"name":"QJM : monthly journal of the Association of Physicians","volume":" ","pages":"697"},"PeriodicalIF":13.3,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690108/pdf/hcab292.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39751235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone mineral density, osteopenia and osteoporosis among US adults with cancer. 美国成年癌症患者的骨矿物质密度、骨质减少和骨质疏松症

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-10-25 DOI: 10.1093/qjmed/hcac015

J-F Huang, Q-C Tan, H Bai, J Wang, M Bergman, Z Wu

{"title":"Bone mineral density, osteopenia and osteoporosis among US adults with cancer.","authors":"J-F Huang, Q-C Tan, H Bai, J Wang, M Bergman, Z Wu","doi":"10.1093/qjmed/hcac015","DOIUrl":"https://doi.org/10.1093/qjmed/hcac015","url":null,"abstract":"Background: Bone mineral deficits are one of the most common complications in cancer survivors. However, there are no studies evaluating bone mineral density (BMD) and the prevalence of osteopenia and osteoporosis among patients with different types of cancers.Aim: The objective was to assess BMD and evaluate the prevalence of osteopenia and osteoporosis among US adults with cancer.Design: A cross-section propensity score matching study.Methods: We extracted data from National Health and Nutrition Examination Survey database from 2005 to 2018. We compared BMD in participants with and without cancer which was further analyzed according to cancer type. We conducted logistic regression to evaluate adjusted odds ratios of osteopenia and osteoporosis and determine risk factors for their development.Results: We found that BMD was significantly higher in participants without cancer than cancer patients. Furthermore, the median BMD of patients with breast cancer or skin cancer (including melanoma) was significantly lower than participants without cancer. People with breast, lung, genitourinary and skin cancers were more likely to incur osteopenia/osteoporosis than those without cancer.Conclusions: BMD differs depending upon type in survivors. Individuals with a history of cancer have a poor understanding of osteoporosis and its risk factors. Understanding risk factors in patients with cancers identified in our study may be helpful for preventing osteoporosis and fractures and the development of screening guidelines.","PeriodicalId":520760,"journal":{"name":"QJM : monthly journal of the Association of Physicians","volume":" ","pages":"653-660"},"PeriodicalIF":13.3,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39746387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Response to: Multisystem inflammatory syndrome following COVID-19 vaccination: ignored and underdiagnosed. 应对:COVID-19疫苗接种后的多系统炎症综合征:被忽视和诊断不足。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-10-25 DOI: 10.1093/qjmed/hcab294

A Kono, P Hawke, R Yoshioka

引用次数: 0

Corticosteroids for mild COVID-19 treatment: opening the floodgates of therapeutic benefits. 用于COVID-19轻度治疗的皮质类固醇:打开治疗益处的闸门。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-10-25 DOI: 10.1093/qjmed/hcab312

N G Kounis, S N Kouni, V Mplani, I Koniari

{"title":"Corticosteroids for mild COVID-19 treatment: opening the floodgates of therapeutic benefits.","authors":"N G Kounis, S N Kouni, V Mplani, I Koniari","doi":"10.1093/qjmed/hcab312","DOIUrl":"https://doi.org/10.1093/qjmed/hcab312","url":null,"abstract":"on the use of corticosteroids for the treatment of mild coronavirus disease 2019 (COVID-19) published in QJM, 1 the authors concluded that it is imperative their cautious use, based on both evidence and common sense. They reported that there is no study, so far, demonstrating tangible benefits of steroid use in mild cases, while future well-designed clinical trials can further prove the merit of corticosteroids in mild cases of COVID-19. There was skepticism regarding the potential risk of viral replication increase, the side-effects as hyperglycemia, risk of secondary infections or reactivation of latent infections and possible steroid shortage in pharmacies and hospitals. However, a previous published meta-analysis and systematic review 2 demonstrated that in the absence of contra-indications and/or side-effects, the use of ste-roids should be considered in coronavirus infection including COVID-19. Interestingly, clinical data have shown that asthma and chronic obstructive pulmonary disease exacerbations, often attributed to viral cause, can be reduced with the use of inhaled corticosteroids, while inhaled glucocorticoids can further reduce the severe acute respiratory syndrome coronavirus 2 replication in airway epithelial cells and down regulate the ex-pression of angiotensin converting enzyme 2 and transmem-brane","PeriodicalId":520760,"journal":{"name":"QJM : monthly journal of the Association of Physicians","volume":" ","pages":"701"},"PeriodicalIF":13.3,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383071/pdf/hcab312.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39577282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: A case of severe interstitial lung disease after COVID-19 vaccination. 更正:1例COVID-19疫苗接种后发生严重间质性肺疾病。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-10-25 DOI: 10.1093/qjmed/hcac066

A Kono, R Yoshioka, P Hawke, K Iwashina, D Inoue, M Suzuki, C Narita, K Haruta, A Miyake, H Yoshida, N Tosaka

引用次数: 1

Mental illness in society as we learn to live with COVID-19. 当我们学会与COVID-19共存时，社会中的精神疾病。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-09-22 DOI: 10.1093/qjmed/hcac207

Seamas C Donnelly

引用次数: 1

Response to: VATS for refractory pneumothorax: a minimal access curative surgery. 对VATS治疗难治性气胸的反应:一种微创治疗手术。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-09-22 DOI: 10.1093/qjmed/hcab275

Y Mitsuyama, S Tanaka, A Ike, J Tanaka, S Fujimi

引用次数: 0

Drug-induced methemoglobinemia. 药物引起高铁血红蛋白症。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-09-22 DOI: 10.1093/qjmed/hcac157

J Hemapriya, Tushar Sehgal, Sudip Kumar Datta, S Arulselvi

引用次数: 1

VATS for refractory pneumothorax: a minimal access curative surgery. VATS治疗难治性气胸:一种微创治疗手术。

IF 13.3

QJM : monthly journal of the Association of Physicians Pub Date : 2022-09-22 DOI: 10.1093/qjmed/hcab274

P Ish, D Behera

引用次数: 0