Otolaryngologia polska = The Polish otolaryngology最新文献

{"title":"The \"engine room\" of a multicentre geriatric otolaryngology network: data curation, quality assurance, and research readiness of the ENT Geriatric Database.","authors":"Małgorzata Wierzbicka, Dorota Świątek, Maksymilian Dwornikowski, Karolina Dżaman, Maria Makuszewska, Dominik Stodulski, Maciej Kawczyński, Paweł Burduk, Wioletta Pietruszewska, Jarosław Markowski, Patrycja Gazińska, Bogusław Mikaszewski","doi":"10.5604/01.3001.0055.7288","DOIUrl":"10.5604/01.3001.0055.7288","url":null,"abstract":"<p><p>&lt;p&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Multi-centre datasets are becoming essential for evidence-based decision-making in geriatric otolaryngology, yet their reliability depends on a transparent and reproducible process of data preparation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim:&lt;/strong&gt; To present the complete \"engine-room\" workflow of the ENT Geriatric Database - a harmonised, anonymised multi-centre dataset - and to demonstrate how systematic data curation supports trustworthy analyses of perioperative risk and outcomes in elderly patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The study integrated 16 Excel files from eight tertiary ENT centres into a unified dataset of 888 patients aged 65 years and older. The scripted pipeline standardised 97 canonical variables using positional and keyword-based mapping, removed personally identifiable information, harmonised heterogeneous coding schemes across 44 variables, and performed a multilevel data-quality audit.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results:&lt;/strong&gt; The workflow revealed major structural and clinical data-quality issues: five variables exceeded 50% overall missingness, 44 had coded-missing categories, and 99 potential duplicates were detected. Five centre-specific block patterns indicated how procedural differences influence data completeness. All cleaned data, missingness matrices, and anomaly logs were exported for independent review.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; A scripted, auditable curation pipeline can transform heterogeneous spreadsheets into a more reliable multicentre dataset. Investing in this \"engine-room\" infrastructure strengthens data validity and provides a more robust basis for perioperative risk estimation and meaningful inter-centre comparisons in geriatric otolaryngology.&lt;/p&gt.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 3","pages":"29-35"},"PeriodicalIF":0.6,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of COVID associated invasive fungal sinusitis.","authors":"Dr Sampurna Ghosh, Dr Neha Padia","doi":"10.5604/01.3001.0055.6613","DOIUrl":"10.5604/01.3001.0055.6613","url":null,"abstract":"<p><strong>Introduction: </strong>Mucormycosis is a life-threatening infection caused by fungi belonging to the order mucorales. Aspergillous and Mucormycetes have been reported as the main fungal pathogens for infection in people with COVID-19. The main risk factors include uncontrolled Diabetes mellitus and steroid use.</p><p><strong>Aim: </strong>The current study aims to analyze the diagnostic indicators, treatment protocols and follow up approach in patients who were affected with post-COVID mucormycosis.</p><p><strong>Methods: </strong>Patients who were admitted to Medicover hospitals with acute sinusitis symptoms were included in the study. Data was collected using a structured proforma which included demographic details, past medical history, days of presentation from COVID-19 diagnosis and symptoms related to eyes, nose and mouth. We noted the Magnetic resonance imaging and Computed tomography findings and blood parameters like Total leukocyte count, C-reactive protein, Erythrocyte sedimentation rate, Glycated hemoglobin and creatinine were monitored. All patients were divided into stages and underwent relevant surgical procedures along with, anti-fungal therapy. Follow up was conducted to see for residual or recurrent disease and survival until 1 year post admission.</p><p><strong>Results: </strong>Total of 23 patients were studied. 17 male and 6 female. 69.5% were diabetic. 91.3% received steroids during COVID treatment. Majority presented within 4 weeks of diagnosis of COVID. CT-SCAN and MRI findings formed the road-map to treatment. All 23 were confirmed mucormycosis based on biopsy reports, but 4 had overlapping Aspergillous infection. All patients were started on amphotericin-B and followed up for disease free status and survival up 1 year. We also monitored CRP levels to declare disease free status.</p><p><strong>Conclusion: </strong>The poor and impaired immune functioning due to COVID infection along with unmonitored use of steroids, was the major cause of rise in mucormycosis. We now know that successful treatment of mucormycosis requires early diagnosis, reversal of underlying predisposing risk factors, surgical debridement and prolonged antifungal therapy.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 2","pages":"14-22"},"PeriodicalIF":0.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Artificial Intelligence Algorithms in Challenging Diagnostic Cases - Between Potential and Real Clinical Support.","authors":"Agata Doligalska-Dolina, Klaudia Ziółkowska, Maciej J Wróbel","doi":"10.5604/01.3001.0055.7287","DOIUrl":"10.5604/01.3001.0055.7287","url":null,"abstract":"<p><strong>Introduction: </strong>Extranodal natural killer/T-cell lymphoma, nasal type (ENKTL), is a rare EBV-associated malignancy characterized by destructive tumors in the nasal cavity, often causing delayed diagnosis due to tissue necrosis. Artificial intelligence (AI) has potential to assist in complex diagnostic challenges.</p><p><strong>Objectives: </strong>This study aimed to evaluate the diagnostic performance and clinical relevance of publicly accessible AI-driven platforms in identifying ENKTL based on a real, challenging clinical case.</p><p><strong>Materials and methods: </strong>Clinical data from a 26-year-old male patient with protracted and complicated symptoms initially suggesting infectious conditions were used. Eight AI symptom assessment platforms were tested for diagnostic outputs using identical anonymized case inputs at early and advanced disease stages. Diagnostic suggestions, alignment with the final histopathological diagnosis, and quality of recommendations were analyzed.</p><p><strong>Results: </strong>Six of eight platforms provided valid differential diagnoses consistent with clinical data. Early-stage data mainly generated infectious diagnoses like peritonsillar abscess. Advanced-stage data shifted diagnoses toward invasive fungal, autoimmune, and malignant diseases, with platforms such as Doctronic and Symptomate explicitly including lymphoma. Diagnostic pathways varied, with recommendations for comprehensive laboratory tests, imaging, biopsies, and immunological assays. AI systems demonstrated oncologic vigilance when EBV viral data were included, emphasizing clinician oversight for accurate diagnosis.</p><p><strong>Conclusions: </strong>AI-based diagnostic platforms show promise in supporting preliminary assessment and differential diagnosis in rare, complex cases such as ENKTL. While AI can guide diagnostic reasoning and propose investigations, it does not replace clinical judgment. Further development and validation of AI tools are needed to enhance their reliability and integration into medical practice.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 2","pages":"39-45"},"PeriodicalIF":0.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of transnasal videoendoscopic-guided botulinum toxin injection in patients with adductor spasmodic dysphonia.","authors":"Olivier Ricard, Emmeline Lagrange, Valérie Fraix, Anna Castrito, Christol Fabre, Paul Castellanos, Ihab Atallah","doi":"10.5604/01.3001.0055.6384","DOIUrl":"10.5604/01.3001.0055.6384","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Adductor spasmodic dysphonia (ASD) is a focal laryngeal dystonia characterized by involuntary vocal fold spasms, resulting in a strained and effortful voice. Botulinum toxin injection is the standard treatment, typically performed using electromyography-guided techniques. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim: &lt;/b&gt;This study evaluates the efficacy of office-based transnasal videoendoscopic-guided botulinum toxin injection as an alternative to electromyography-guided percutaneous injection in patients with adductor spasmodic dysphonia (ASD). &lt;br&gt;&lt;br&gt;&lt;b&gt;Methods:&lt;/b&gt; A cohort of patients with ASD underwent transnasal laryngeal injections of botulinum toxin using a flexible video endoscope. Local anesthesia was administered, and a flexible needle was used to inject botulinum toxin into the vocal and/or vestibular folds. Phonation was assessed before and after the procedure. &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; Twenty-seven patients with ASD showed significant improvements in VHI-10 (Voice Handicap Index-10) and VRQOL (Voice Related Quality of Life) scores post-injection. Additionally, the GRBAS scale scores improved after the procedure. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Office-based transnasal videoendoscopic-guided botulinum toxin injection is a reliable and straightforward technique for treating ASD. It can be performed without electromyography, making it accessible for all laryngologists.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 3","pages":"1-6"},"PeriodicalIF":0.6,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147583554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olfactory abilities in children 4-10 years old. The need for screening tests.","authors":"Agnieszka Hamerlińska, Magdalena Zając","doi":"10.5604/01.3001.0055.6608","DOIUrl":"10.5604/01.3001.0055.6608","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Odor processing provides a unique window into the interaction between perception, language, and memory during development. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; This study investigated how children aged 4-10 identify and name odors, focusing on age-related changes, potential gender differences, and priming effects between recognition and naming. &lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; Using a cross-sectional experimental design, we measured both accuracy and response times for odor identification and naming. Children identified on average 5 odors (17.62 s) and named 4 (13.14 s), with mint and coffee being most reliably recognized and rose and banana least. Age robustly predicted both identification (R = 0.14) and naming performance (R = 0.24), whereas gender exerted no influence. Notably, prior identification facilitated subsequent naming, particularly in older children, consistent with the idea that semantic activation supports lexical access. &lt;br&gt;&lt;br&gt;&lt;b&gt;Discussion:&lt;/b&gt; These findings demonstrate that olfactory cognition develops significantly during middle childhood, highlighting odor naming as a sensitive marker of the integration between perceptual and linguistic systems. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Beyond descriptive patterns, our results suggest that odor-based paradigms can serve as a powerful tool for probing mechanisms of semantic development and may inform early detection of atypical cognitive trajectories.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 3","pages":"1-8"},"PeriodicalIF":0.6,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147583573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartphone-Based Hearing Testing Versus Clinical Audiometry: A Comparative Study in Ear, Nose, and Throat Practice.","authors":"Ciara Prendergast, Rachel Delahunt, Emily Green, Eva Donlon, Eoin Kavanagh, Aleksandra Ślęzak, Justyna Branewska, Magdalena Ostrowska, Maciej J Wróbel","doi":"10.5604/01.3001.0055.6407","DOIUrl":"10.5604/01.3001.0055.6407","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Hearing loss affects millions worldwide, yet access to timely audiometric testing remains limited. Mobile applications offer the potential for convenient, low-cost screening and monitoring outside the clinic. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; This study evaluates the Mimi Hearing Test app, focusing on its diagnostic accuracy, reliability, and overall user experience compared with the clinical standard. &lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; Thirty adult patients from an otolaryngology clinic participated in this comparative study. Each underwent 2 assessments, a traditional pure-tone audiogram performed by an audiologist and a digital hearing test using the Mimi Hearing Test app. Participants then completed a questionnaire rating the app&apos;s usability, clarity of results, and suitability for at-home use. &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; The study found a strong concordance between the pure tone average values obtained from the Mimi Hearing Test app and those from clinical audiometry, especially in participants with normal or moderate hearing loss. Discrepancies were noted in cases of profound and asymmetric hearing loss, where the app sometimes underestimated hearing thresholds. Patient feedback was generally positive, with a significant interest in regular at-home monitoring. Neutral or negative impressions were more common among older participants, highlighting the need for age-sensitive design and user support with digital health tools. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The Mimi Hearing Test app demonstrates strong potential as a screening and monitoring tool for individuals with mild-to-moderate hearing impairment. While it is not a substitute for formal clinical audiometry testing in complex cases, it serves as an effective complementary tool that can raise patient awareness, encourage self-monitoring, and support earlier interventions in hearing health.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 2","pages":"6-13"},"PeriodicalIF":0.6,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147501492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the eighth and ninth editions of American Joint Committee on Cancer/Union for International Cancer Control staging for non-metastatic nasopharyngeal carcinoma.","authors":"Guoping Cheng, Xiuzhen Zhang, Yuting Fang, Binhao Wu, Rong Zhang, Xiaozhong Chen, Caineng Cao","doi":"10.5604/01.3001.0055.6383","DOIUrl":"10.5604/01.3001.0055.6383","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; The ninth edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) tumor-node-metastasis (TNM) system for patients with non-metastatic nasopharyngeal carcinoma (NPC) was based on data from endemic regions, and it required validation for application to non-endemic regions. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; The aim of this study was to compare the performance of the 8&lt;sup&gt;th&lt;/sup&gt; and the 9&lt;sup&gt;th&lt;/sup&gt; editions of the AJCC/UICC TNM system for patients with non-metastatic NPC from non-endemic regions. &lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; Using the Surveillance, Epidemiology, and End Results (SEER) database, 2004-2021, we re-classified NPC patients using 8&lt;sup&gt;th&lt;/sup&gt; and the 9&lt;sup&gt;th&lt;/sup&gt; edition staging based on surrogate markers of advanced radiological extranodal extension (nodes described as \"fixed\") and compared the prediction performance of both staging editions for overall survival (OS) and cancer specific survival (CSS). &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; Our analysis included 4981 patients with a median follow-up of 99.0 months. Comparing the 9&lt;sup&gt;th&lt;/sup&gt; version of AJCC/UICC (TNM-9) with TNM-8, only 29 (1.8%) patients with N1 and 47 (3.3%) patients with N2 were upstaged to N3 in TNM-9. In comparisons based on OS, TNM-9 did not outperform TNM-8 with regard to hazard consistency (2.2326 &lt;i&gt;vs&lt;/i&gt; 1.9160), hazard discrimination (1.4092 &lt;i&gt;vs&lt;/i&gt; 1.0947), sample size balance (0.3476 &lt;i&gt;vs&lt;/i&gt; 0.3398), and percent variance explained (0.2704 &lt;i&gt;vs&lt;/i&gt; 0.2704). The area under the receiver operating characteristic curve (AUC) values of TNM-9 and TNM-8 were 0.5299 and 0.5330 for OS (P = 0.549), respectively. The AUC values of TNM-9 and TNM-8 were 0.5332 and 0.5357 for CSS (P = 0.345), respectively. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Restaging according to TNM-9 criteria involved only minor changes in the distribution of nodal (N) categories. Neither the TNM-9 nor the TNM-8 staging system demonstrated adequate overall discrimination between each stage group classification in terms of OS and CSS for patients with non-metastatic NPC from a non-endemic region.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 2","pages":"23-30"},"PeriodicalIF":0.6,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147501381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic mutations in salivary duct carcinoma.","authors":"Hiromi Nagano, Satoshi Kiyama, Takayuki Kyutoku, Hayato Matsumoto, Masaru Yamashita","doi":"10.5604/01.3001.0055.5900","DOIUrl":"10.5604/01.3001.0055.5900","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Although genetic mutations have been reported in salivary duct carcinoma (SDC), no scientifically validated targeted therapies are currently available. Moreover, cancer genomic profiling tests remain underutilized in clinical practice. These issues highlight the urgent need to elucidate the genomic landscape of SDC and its potential therapeutic relevance. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; This study aimed to characterize the mutational profile of recurrent and/or metastatic SDC. &lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; Data were analyzed for 207 consecutive patients with SDC registered at the Japan National Cancer Center, Center for Cancer Genomics and Advanced Therapeutics (C-CAT) between June 2019 and October 2025. Genetic mutations were determined by next-generation sequencing. Survival of patients was determined by the log-rank test and the Cox proportional hazards model. &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; The top 10 mutations in SDC were &lt;i&gt;TP53&lt;/i&gt; (74.4%), &lt;i&gt;ERBB2&lt;/i&gt; (52.2%), &lt;i&gt;NF1&lt;/i&gt; (32.4%), &lt;i&gt;CDK12&lt;/i&gt; (29.0%), &lt;i&gt;PIK3CA&lt;/i&gt; (28.0%), &lt;i&gt;NOTCH3&lt;/i&gt; (19.8%), &lt;i&gt;LTK&lt;/i&gt; (18.4%), &lt;i&gt;CDKN2A&lt;/i&gt; (18.4%), &lt;i&gt;BRCA2&lt;/i&gt; (16.9%), &lt;i&gt;SPEN&lt;/i&gt; (16.9%), with 17.1 7.2 (mean standard error of the mean [SEM]) mutations/individual. &lt;i&gt;TP53&lt;/i&gt; mutations (p = 0.005707) were associated with a significantly worse prognosis, as determined by log-rank test. The hazard ratios for cases with this mutation was 2.6390 (95% CI, 1.2180-5.720, p = 0.0139) for &lt;i&gt;TP53&lt;/i&gt;. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; This study delineated the mutational spectrum of recurrent and/or metastatic SDC. Even in advanced disease, prognostically relevant mutations were identified, emphasizing the clinical importance of cancer genomic profiling tests.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 3","pages":"1-7"},"PeriodicalIF":0.6,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147725498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Burden in Subglottic Stenosis: The Prevalence of Depression and Anxiety.","authors":"Alison M Hawkins, Lenise G Soileau, Michael D Rockwell, Nizar Tejani, Karuna Dewan","doi":"10.5604/01.3001.0055.5832","DOIUrl":"10.5604/01.3001.0055.5832","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Subglottic stenosis (SGS) is a rare, recurring fibroinflammatory disease that causes upper airway narrowing and severe dyspnea. Patients often require multiple surgeries due to chronic restenosis. The unpredictable nature of SGS may significantly affect psychological well-being. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; The aim of this study is to determine the prevalence of depression and anxiety in SGS patients and identify associated risk factors. &lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; A retrospective chart review was conducted of patients diagnosed with SGS at a tertiary care center from 2012 to 2022. Data collected included demographics, SGS etiology, number/type of surgeries, tracheostomy history, pulmonary function tests, medications, and psychiatric history. Statistical analyses included t-tests, chi-square, and ANOVA with Bonferroni correction. &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; Of 246 patients (mean age 54, body mass index [BMI] 32 8.7), 16% had a clinical diagnosis of depression, and 49% reported a history of anxiety or depression. Patients with psychiatric comorbidities were older (57.7 vs 52.1 years, p&lt;0.05). Intubation was the leading cause of SGS (41.9%) and significantly associated with depression (p = 0.03). Patients with depression had higher rates of hospital admission within a year (p = 0.00). Interestingly, those with mental health hospitalizations were significantly younger (p = 0.01). &lt;br&gt;&lt;br&gt;&lt;b&gt;Discussion:&lt;/b&gt; Depression and anxiety are more prevalent in SGS patients than in the general population. Contributing factors include age, etiology (particularly intubationrelated SGS), and surgical burden. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Mental health should be an integral part of SGS management. Future prospective studies using standardized symptom surveys may better capture the psychological impact of SGS and inform holistic patient care.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 1","pages":"17-23"},"PeriodicalIF":0.6,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic therapy in adult patients with infectious mononucleosis in the prehospital period - a single-center experience.","authors":"Maciej Bura, Michał Michalak, Sandra Dachowska, Jan Haraj, Kacper Sochacki, Kinga Woźniak, Anna Olewicz, Arleta Kowala-Piaskowska","doi":"10.5604/01.3001.0055.4889","DOIUrl":"10.5604/01.3001.0055.4889","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Some viral pharyngitis can mimic streptococcal pharyngitis. The clinical similarity of infectious mononucleosis (IM) and streptococcal pharyngitis makes differential diagnosis based on the clinical picture alone tricky, and patients with IM may be treated empirically with antibiotics (ATBs). &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; To assess prehospital ATB use in adult patients with IM admitted to the hospital. In addition, to compare antibiotic-treated individuals and patients not treated with ATBs using selected demographic, clinical, and laboratory parameters. &lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; Medical records of patients with a laboratory-confirmed IM diagnosis (2006-2023) from one center in Poland were analyzed. &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; Out of one hundred and forty-four patients, 119 (82.6%) were treated with ATBs in the prehospital period. Many patients (n = 59) received more than one ATB. The most common choices were amoxicillin/clavulanate (46.2%), cefuroxime (27.7%), and macrolides (26.1%). One-fourth of patients had palpebral edema (more commonly in subjects treated with ATBs). The enlarged spleen was found in almost 90% of individuals with an available abdominal ultrasound assessment (113/127). A significant proportion of patients (43.1%) were given steroids (more commonly in subjects treated with ATBs). &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; More severe IM in young adults is a common cause of ATB therapy. Broad-spectrum ATBs are often prescribed. Meticulous clinical evaluation supported by simple and widely available diagnostic tools could reduce the use of antimicrobials in such a patient population.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"80 2","pages":"1-5"},"PeriodicalIF":0.6,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147350247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}