Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace最新文献

{"title":"Safety and feasibility of physiotherapy in ICU-admitted severe COVID-19 patients: an observational study.","authors":"Veronica Rossi,&nbsp;Martina Santambrogio,&nbsp;Cesare Del Monaco,&nbsp;Mariangela Retucci,&nbsp;Serena Tammaro,&nbsp;Clara Ceruti,&nbsp;Laura Saderi,&nbsp;Stefano Aliberti,&nbsp;Emilia Privitera,&nbsp;Giacomo Grasselli,&nbsp;Giovanni Sotgiu,&nbsp;Francesco Blasi","doi":"10.4081/monaldi.2022.2087","DOIUrl":"https://doi.org/10.4081/monaldi.2022.2087","url":null,"abstract":"<p><p>Early physiotherapy could play an important role in the management of severe COVID-19 subjects with consequences of prolonged ICU stay, although its effectiveness is still unclear. Aim of this study is to describe physiotherapy performed in severe COVID-19 patients and to evaluate its safety and feasibility. Consecutive adults with confirmed SARS-CoV-2 infection, admitted to the ICU, needing invasive mechanical ventilation for >24 hours and receiving early physiotherapy, have been enrolled. Adverse events occurred during physiotherapy sessions and timing and type of physiotherapy delivered were analysed, to identify the interventions most frequently performed and to determine the time taken to first mobilize, stand and walk. Functional and clinical assessment of patients was also performed at hospital discharge. Eighty-four severe COVID-19 subjects were enrolled. Few minor adverse events were recorded. Active mobilization was promoted over passive mobilization and independence in daily life activities was supported. Time interval from patients' intubation to the first physiotherapy treatment was 13 days and to walking was 27 days. Forty-eight (57.1%) subjects returned at home, whereas 29 (34.5%) were discharged to in-patient rehabilitation. Patients with tracheostomy experienced a delay in time from ICU admission until sit out of bed and ambulation, if compared with subjects without tracheostomy, although no differences were found in 6MWT and 1m-STST performances. This study reporting early physiotherapy during pandemic suggests that this intervention is feasible and safe for severe COVID-19 subjects, as well as healthcare workers, although delayed compared to other critically ill patients.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39864395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of IP-10 during follow up of pulmonary tuberculosis patients.","authors":"Himanshu Saini,&nbsp;Parul Mrigpuri,&nbsp;Balakrishnan Menon,&nbsp;Sonal Sonal","doi":"10.4081/monaldi.2022.2022","DOIUrl":"https://doi.org/10.4081/monaldi.2022.2022","url":null,"abstract":"<p><p>Pulmonary tuberculosis (PTB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) and is associated with significant mortality and morbidity. There has been a number of advances in the diagnosis of PTB but there is a need for simple blood based diagnostic test. A follow up of the patients on treatment remains challenging. This study was planned to evaluate the role of IP-10 in the follow up of PTB patients. A total of 60 subjects were enrolled in the study, 40 patients with confirmed diagnosis of PTB and 20 healthy controls. The value of interferon (IFN)γ inducible protein 10 (IP10) was measured in all the subjects at the start of the treatment and at a follow up of two months. Mean age of the study subjects was 40.96 years. Mean duration of symptoms at presentation was 1 month and 17 days. The induration on Tuberculin skin test (TST) was between 10-20mm in most (62.5%) of the study subjects. Majority (45%) showed moderately advanced disease on chest x-ray. There was no association of IP-10 with TST diameter and gene x-pert. Similarly, no significant difference in IP-10 levels was found in relation to sputum grading and x-ray score at diagnosis and after 2 months of treatment. IP-10 has very limited role in diagnosis of active TB in especially in high TB burden countries. The role of IP-10 in follow up of PTB patients could not be ascertained by our study. However, more studies are needed in this pretext with larger sample size and extended duration of follow up.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39864394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post severe COVID-19 infection lung damages study. The experience of early three months multidisciplinary follow-up.","authors":"Lucrezia De Michele,&nbsp;Paola Pierucci,&nbsp;Guido Giovannetti,&nbsp;Michele De Ceglie,&nbsp;Michela Dimitri,&nbsp;Alessandra Mirabile,&nbsp;Vitaliano Quaranta,&nbsp;Arnaldo Scardapane,&nbsp;Carlo D'Agostino,&nbsp;Giovanna Elisiana Carpagnano","doi":"10.4081/monaldi.2022.2142","DOIUrl":"https://doi.org/10.4081/monaldi.2022.2142","url":null,"abstract":"<p><p>The correct type and time of follow-up for patients affected by COVID19 ARDS is still unclear. The aim of this study was to evaluate at the survivors to COVID19 ARDS requiring non-invasive respiratory support (NRS) admitted to a Respiratory Intensive care unit (RICU) from March 8th till May 31th 2020 looking at all sequelae via a comprehensive follow up. All patients underwent a multi-disciplinary instrumental and clinical assessment within three months form admission to evaluate all infection related sequelae. Thirty-eight patients were enrolled Lung-Ultrasound (LUS) showed an outstanding discrimination ability (ROC AUC: 0.95) and a substantial agreement rate (Cohen's K: 0.74) compared to chest CT-scan detecting improvement of lung consolidations. Youden's test showed a cut-off pressure of 11 cmH2O ExpiratoryPAP-Continuous-PAP-max (EPAP-CPAP) applied at the airways during hospitalization to be significantly correlated (p value: 0.026) to the increased pulmonary artery common trunk diameter. A total of 8/38 patients (21.8%), 2 of whom during follow-up, were diagnosed with Pulmonary Emboli (PE) and started anticoagulant treatment. Patients with PE had a statistically significant shorter length of time of hospitalization, time to negative swab, CPAP/NIV duration, P/F ratio and D-dimers at follow-up compared to non PE. A comprehensive approach to patients with ARDS COVID19 requiring NRS is necessary. This study highlighted cardiopulmonary impairment related to the ARDS and to the high-EPAP-CPAP-max greater than 11mmHg provided during admission, the usefulness of LUS in monitoring post-infection recovery and the correct identification and  treatment of patients with PE during follow up.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39708385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of ivermectin on non-severe and severe COVID-19 disease and gender-based difference of its effectiveness.","authors":"Syed Muhammad Zubair,&nbsp;Muhammad Waleed Chaudhry,&nbsp;Ali Bin Sarwar Zubairi,&nbsp;Talha Shahzad,&nbsp;Aqusa Zahid,&nbsp;Ibrahim Ali Khan,&nbsp;Javaid Ahmed Khan,&nbsp;Muhammad Irfan","doi":"10.4081/monaldi.2022.2062","DOIUrl":"https://doi.org/10.4081/monaldi.2022.2062","url":null,"abstract":"<p><p>The COVID-19 pandemic has led to mortality and morbidity since December 2019. Many possible treatment options have been advised till date. The role of ivermectin in the treatment of COVID-19 disease remains controversial. The aim of our study was to evaluate the effect of ivermectin in hospitalized patients with non-severe and severe COVID-19 disease. We conducted a retrospective cohort study that compared outcomes in 2 groups of COVID-19 patients hospitalized at the largest tertiary care center of Pakistan. The study group was given ivermectin along with standard treatment of covid-19 disease; the comparison group was not. Data on mortality, inflammatory markers such as C-reactive protein (CRP) and ferritin, length of hospital stay and baseline characteristics were collected from Aga Khan University's database from October 2020 till February 2021. Statistical analysis was done to determine the effectiveness of ivermectin in non-severe and severe COVID-19. Comparison of effectiveness of Ivermectin in both the genders was also conducted. The cohort included 188 patients out of which 90 were treated with ivermectin. Mortality and length of hospitalization was not found to be significantly different in the study group compared with the control group (5.6% vs 5.1%; p=0.87 and 5 days vs 4 days; p=0.27). Analysis of secondary outcomes did not yield statistically significant results, apart from ferritin levels which were significantly less in patients treated with ivermectin (547.1 vs 756.7; p=0.03). The ferritin and CRP levels in affected males were higher than in females on admission and discharge. Our findings suggest ivermectin does not significantly affect all-cause mortality, length of hospitalization and CRP levels in hospitalized COVID-19 patients. Large scale randomized controlled trials (RCTs) are required to further evaluate the role of ivermectin in covid-19 disease.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39945350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants, risk factors and spatial analysis of multi-drug resistant pulmonary tuberculosis in Jodhpur, India.","authors":"Nikhilesh Ladha,&nbsp;Pankaj Bhardwaj,&nbsp;Nishant Kumar Chauhan,&nbsp;Kikkeri Hanumantha Setty Naveen,&nbsp;Vijaya Lakshmi Nag,&nbsp;Dandabathula Giribabu","doi":"10.4081/monaldi.2022.2026","DOIUrl":"https://doi.org/10.4081/monaldi.2022.2026","url":null,"abstract":"<p><p>This study was planned to estimate the proportion of confirmed multi-drug resistance pulmonary tuberculosis (TB) cases out of the presumptive cases referred to DTC (District Tuberculosis Center) Jodhpur for diagnosis; to identify clinical and socio-demographic risk factors associated with the multidrug-resistant pulmonary TB and to assess the spatial distribution to find out clustering and pattern in the distribution of pulmonary TB with the help of Geographic Information System (GIS). In the Jodhpur district, 150 confirmed pulmonary multi-drug resistant tuberculosis (MDR-TB) cases, diagnosed by probe-based molecular drug susceptibility testing method and categorized as MDR in DTC's register (District Tuberculosis Center), were taken. Simultaneously, 300 control of confirmed non-MDR or drug-sensitive pulmonary TB patients were taken. Statistical analysis was done with logistic regression. In addition, for spatial analysis, secondary data from 2013-17 was analyzed using Global Moran's I and Getis and Ordi (Gi*) statistics. In 2012-18, a total of 12563 CBNAAT (Cartridge-based nucleic acid amplification test) were performed. 2898 (23%) showed M. TB positive but rifampicin sensitive, and 590 (4.7%) showed rifampicin resistant. Independent risk factors for MDR TB were ≤60 years age (AOR 3.0, CI 1.3-7.1); male gender (AOR 3.4, CI 1.8-6.7); overcrowding (AOR 1.6, CI 1.0-2.7); using chulha (smoke appliance) for cooking (AOR 2.5, CI 1.2-4.9), past TB treatment (AOR 5.7, CI 2.9-11.3) and past contact with MDR patient (AOR 10.7, CI 3.7-31.2). All four urban TUs (Tuberculosis Units) had the highest proportion of drug-resistant pulmonary TB. There was no statistically significant clustering, and the pattern of cases was primarily random. Most of the hotspots generated were present near the administrative boundaries of TUs, and the new ones mostly appeared in the area near the previous hotspots. A random pattern seen in cluster analysis supports the universal drug testing policy of India. Hotspot analysis helps cross administrative border initiatives with targeted active case finding and proper follow-up.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39708386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic granulomatous 'Aspergillus lung mass'.","authors":"Kavitha Venkatnarayan,&nbsp;Uma Devaraj,&nbsp;Uma Maheswari Krishnaswamy,&nbsp;Priya Ramachandran,&nbsp;Sreekar Balasundaram,&nbsp;Anuradha Ananthamurthy,&nbsp;Jayanthi Savio","doi":"10.4081/monaldi.2020.1371","DOIUrl":"https://doi.org/10.4081/monaldi.2020.1371","url":null,"abstract":"<p><p>The diverse clinicopathological spectrum of pulmonary aspergillosis is a consequence of varying levels of invasiveness of this ubiquitous fungus, which largely depends on the host immune response and pre-existing lung disease. The clinical presentation of pulmonary aspergillosis spans a wide spectrum from hypersensitivity to life threatening angio-invasive and disseminated disease. We report the case of a young immunocompetent male with no underlying lung disease, who presented with an incidentally detected 'infective mass' lesion in the lung associated with minimal respiratory symptoms. The diagnostic challenges posed by the unusual clinical, radiological and histological picture as well as the therapeutic dilemmas faced are discussed in this report.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/monaldi.2020.1371","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38447435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual cause of 'tree-in-bud' appearance in CT-chest during COVID-19 pandemic.","authors":"Ankur Sharma,&nbsp;Balakrishnan Narayanan,&nbsp;Nilay Pal,&nbsp;Sunny Taye","doi":"10.4081/monaldi.2020.1466","DOIUrl":"https://doi.org/10.4081/monaldi.2020.1466","url":null,"abstract":"<p><p>'Tree-in-bud' (TIB) appearance in computed tomography (CT) chest is most commonly a manifestation of infection. We here describe an unusual cause of TIB during the COVID-19 pandemic. A young male patient who had a history of fever, cough, and respiratory distress presented in the emergency department. As these symptoms matched with coronavirus infection, the COVID-19 test was done, which was found negative. He was then moved to the intensive care unit where he developed severe acute respiratory distress syndrome and was put on mechanical ventilation. Further workup did not reveal any source of infection, as all his cultures were negative, but his CT chest showed a tree-in-bud appearance. After obtaining a detailed history from his friends, the patient was found a chronic abuser of inhaled cocaine and treated with intravenous steroids. Subsequently, he was weaned from the ventilator and discharged from the intensive care unit after becoming asymptomatic.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/monaldi.2020.1466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38344402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 and tuberculosis co-infection: a neglected paradigm.","authors":"Arkapal Bandyopadhyay,&nbsp;Sarika Palepu,&nbsp;Krishna Bandyopadhyay,&nbsp;Shailendra Handu","doi":"10.4081/monaldi.2020.1437","DOIUrl":"https://doi.org/10.4081/monaldi.2020.1437","url":null,"abstract":"<p><p>COVID-19 has been affecting mankind round the globe. The incidence of this infectious disease of respiratory origin is constantly on rise. Another infectious disease widely prevalent is tuberculosis (TB). During past corona virus pandemics of Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome, coinfection with TB was seen. We present this review as the co-infection of COVID-19 with TB has not been assessed yet, imposing a greater global threat. We suggest few measures to be implemented without delay for effectively screening the suspects of co-infection and also follow up of non-suspect patients in the post-pandemic phase.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/monaldi.2020.1437","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38344401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cystic fibrohistiocytic tumour of the lung presenting with recurrent pneumothoraces: a case report.","authors":"Christos Kakos,&nbsp;Savvas Lampridis,&nbsp;Georgios Geropoulos,&nbsp;Reena Khiroya,&nbsp;Achilleas Antonopoulos,&nbsp;Sofoklis Mitsos,&nbsp;Nikolaos Panagiotopoulos","doi":"10.4081/monaldi.2020.1398","DOIUrl":"https://doi.org/10.4081/monaldi.2020.1398","url":null,"abstract":"<p><p>Cystic fibrohistiocytic tumour of the lung is a very rare pathological entity that occurs either as a primary pulmonary neoplasm or as a metastasis from skin lesions called cellular fibrous histiocytomas. Herein, we present the case of a 19-year old man with a history of recurrent pneumothoraces who was managed surgically and was eventually diagnosed with cystic fibrohistiocytic tumour of the lung. Clinicians should include this disease in the differential diagnosis of pulmonary cystic lesions and be aware of its association with cellular fibrous histiocytoma. Reporting of more cases is warranted to further elucidate the natural course of the disease and optimise its management.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/monaldi.2020.1398","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38344400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bedside wireless lung ultrasound for the evaluation of COVID-19 lung injury in senior nursing home residents.","authors":"Frank Lloyd Dini,&nbsp;Carlo Bergamini,&nbsp;Aldo Allegrini,&nbsp;Massimo Scopelliti,&nbsp;Gianmarco Secco,&nbsp;Mario Miccoli,&nbsp;Stefano Boni,&nbsp;Raffaella Brigada,&nbsp;Stefano Perlini","doi":"10.4081/monaldi.2020.1446","DOIUrl":"https://doi.org/10.4081/monaldi.2020.1446","url":null,"abstract":"<p><p>Lung Ultrasound (LUS) is regarded to be potentially useful to diagnose lung injury in older adults living in nursing homes with suspected COVID-19 pneumonia. We aimed at evaluating presence lung injury among senior nursing home residents by LUS performed with portable wireless scanner echography. The study population consisted of 150 residents with a mean age of 88 years (85% female) residing in 12 nursing homes in Northern Italy. Subjects had to have a history of recent onset of symptoms compatible with COVID-19 pneumonia or have been exposed to the contagion of patients carrying the disease. COVID-19 testing was performed with SARS-CoV-2 nasal-pharyngeal (NP) swabs. Positive subjects to LUS scanning were considered those with non-coascelent B-lines in >3 zones, coalescent B-lines in >3 zones and with iperdensed patchy non-consolidated lungs. Sixty-three percent had positive NP testing and 65% had LUS signs of pulmonary injury. LUS had a sensitivity of 79% in predicting positive NP testing. Sixteen percent of residents tested negative for SARSCoV-2 carried the signs of COVID-19 lung injury at LUS. There were 92 patients (61%) with current or recent symptoms.Positivity to LUS scanning was reported in 73% of residents with symptoms, while it was 53% in those without (P=0.016). A positive NP testing was observed in 66% of residents with symptoms and in 57% of those without (P=0.27). We conclude that assessment of LUS by portable wireless scanner echography can be profitability utilized to diagnose lung injury among senior nursing home residents with or without symptoms compatible with COVID-19 pneumonia.</p>","PeriodicalId":520711,"journal":{"name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2020-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/monaldi.2020.1446","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38431788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}