Jesse R Fann, Jessica Vanderlan, Benjamin W Brewer, Cheyenne Corbett, Jennifer Keller, Sheila Lahijani, Shehzad K Niazi, Michelle B Riba, Barbara Andersen, Chloe E Atreya, IIana Braun, William S Breitbart, Yamna Channa, Jill Farabelli, Stewart Fleishman, Sofia Garcia, Donna B Greenberg, Rev George F Handzo, Amy Horyna, Chao-Hui Huang, Sean Hutchinson, Shelley Johns, Shannon La Cava, Heather Leeper, Sara Martin, Debraj Mukherjee, Megan Pailler, Francine Parnes, Vinay Rao, Xiomara Rocha-Cadman, Eli Scher, Jessica Schuster, Lora M A Thompson, Angela Usher, Alan D Valentine, Sarah Montgomery, Susan Darlow
{"title":"NCCN Guidelines® Insights: Distress Management, Version 1.2026.","authors":"Jesse R Fann, Jessica Vanderlan, Benjamin W Brewer, Cheyenne Corbett, Jennifer Keller, Sheila Lahijani, Shehzad K Niazi, Michelle B Riba, Barbara Andersen, Chloe E Atreya, IIana Braun, William S Breitbart, Yamna Channa, Jill Farabelli, Stewart Fleishman, Sofia Garcia, Donna B Greenberg, Rev George F Handzo, Amy Horyna, Chao-Hui Huang, Sean Hutchinson, Shelley Johns, Shannon La Cava, Heather Leeper, Sara Martin, Debraj Mukherjee, Megan Pailler, Francine Parnes, Vinay Rao, Xiomara Rocha-Cadman, Eli Scher, Jessica Schuster, Lora M A Thompson, Angela Usher, Alan D Valentine, Sarah Montgomery, Susan Darlow","doi":"10.6004/jnccn.2026.0018","DOIUrl":"10.6004/jnccn.2026.0018","url":null,"abstract":"<p><p>These NCCN Guidelines for Distress Management discuss the identification and treatment of psychosocial problems in patients with cancer. They are intended to assist oncology teams to identify patients who require referral to psychosocial resources and to give oncology teams guidance on interventions for patients with significant distress. These guidelines also provide guidance for social workers, certified chaplains, and mental health professionals by describing treatments and interventions for various psychosocial problems as they relate to patients with cancer. These NCCN Guidelines Insights summarize the panel's most recent recommendations regarding standards of care for distress management in patients with cancer and implementation of these standards, including application of evidence-based care delivery models, such as the collaborative care model.</p>","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 4","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147648718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gregory J Riely, Douglas E Wood, Dara L Aisner, Andrea L Axtell, Jessica R Bauman, Ankit Bharat, Joe Y Chang, Aakash Desai, Thomas J Dilling, Jonathan Dowell, Gregory A Durm, Scott Gettinger, Travis E Grotz, Matthew A Gubens, Aditya Juloori, Rudy P Lackner, Michael Lanuti, Benjamin Levy, Jules Lin, Billy W Loo, Christine M Lovly, Fabien Maldonado, Daniel Morgensztern, Trey C Mullikin, Thomas Ng, Dawn Owen, Dwight H Owen, Tejas Patil, Patricio M Polanco, Jonathan Riess, Ana Lucia Ruano Mendez, Theresa A Shapiro, Aditi P Singh, James Stevenson, Alda Tam, Tawee Tanvetyanon, Jane Yanagawa, Edwin Yau, Karen Yun, Kristina Gregory, Lisa Hang
{"title":"Non-Small Cell Lung Cancer, Version 4.2026, NCCN Clinical Practice Guidelines In Oncology.","authors":"Gregory J Riely, Douglas E Wood, Dara L Aisner, Andrea L Axtell, Jessica R Bauman, Ankit Bharat, Joe Y Chang, Aakash Desai, Thomas J Dilling, Jonathan Dowell, Gregory A Durm, Scott Gettinger, Travis E Grotz, Matthew A Gubens, Aditya Juloori, Rudy P Lackner, Michael Lanuti, Benjamin Levy, Jules Lin, Billy W Loo, Christine M Lovly, Fabien Maldonado, Daniel Morgensztern, Trey C Mullikin, Thomas Ng, Dawn Owen, Dwight H Owen, Tejas Patil, Patricio M Polanco, Jonathan Riess, Ana Lucia Ruano Mendez, Theresa A Shapiro, Aditi P Singh, James Stevenson, Alda Tam, Tawee Tanvetyanon, Jane Yanagawa, Edwin Yau, Karen Yun, Kristina Gregory, Lisa Hang","doi":"10.6004/jnccn.2026.0017","DOIUrl":"10.6004/jnccn.2026.0017","url":null,"abstract":"<p><p>The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Non-Small Cell Lung Cancer (NSCLC) provide recommendations for the treatment of patients with NSCLC, including diagnosis, primary disease management, surveillance, and subsequent treatment. The panel has updated the list of recommended targeted therapies based on recent FDA approvals and clinical data. This selection from the NCCN Guidelines for NSCLC focuses on treatment recommendations for advanced or metastatic NSCLC with actionable biomarkers.</p>","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 4","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147648823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Curing Prostate Cancer?","authors":"Daniel M Geynisman","doi":"10.6004/jnccn.2026.0019","DOIUrl":"https://doi.org/10.6004/jnccn.2026.0019","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 4","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147648721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fayaz Khan, Madhu Bhargavi Chandra, Zuhair Alam, Akshay Sridhar
{"title":"CLO26-112: Durvalumab Versus Pembrolizumab With Gemcitabine and Cisplatin in First-Line Treatment of Advanced Biliary Tract Cancer: A Real-World Comparative Effectiveness Analysis.","authors":"Fayaz Khan, Madhu Bhargavi Chandra, Zuhair Alam, Akshay Sridhar","doi":"10.6004/jnccn.2025.7384","DOIUrl":"10.6004/jnccn.2025.7384","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 3.5","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monique Gary, Mark Hiatt, John Cole, Alicia Battle, John Stewart, Sara Horton, Steven Chen, Cary Kaufman, Tedd Mitchell
{"title":"HSR26-231: Diagnostic Performance of the Bexa™ Breast Exam for Detection of Breast Masses: A Prospective Single-Center Study.","authors":"Monique Gary, Mark Hiatt, John Cole, Alicia Battle, John Stewart, Sara Horton, Steven Chen, Cary Kaufman, Tedd Mitchell","doi":"10.6004/jnccn.2025.7187","DOIUrl":"10.6004/jnccn.2025.7187","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 3.5","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CRE26-051: Sciatic Nerve-Sparing Limb Salvage Surgery in Giant Infected Myxofibrosarcoma: A Case Report of Functional Success and Fatal Metastatic Complications.","authors":"Pattana Ongkasuwan","doi":"10.6004/jnccn.2025.7145","DOIUrl":"10.6004/jnccn.2025.7145","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 3.5","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rowan Bandaranaike, Mohammad Hashki, Sanad Alhushki, Sahanna Shiggaon, Aakash Desai, Benjamin Wei, James Donahue, Roshini Pasala, Maya Khalil
{"title":"BPI26-026: Comparative Survival Analysis of Neoadjuvant vs Adjuvant Chemoimmunotherapy in Non-Small Cell Lung Cancer: Insights From the National Cancer Database.","authors":"Rowan Bandaranaike, Mohammad Hashki, Sanad Alhushki, Sahanna Shiggaon, Aakash Desai, Benjamin Wei, James Donahue, Roshini Pasala, Maya Khalil","doi":"10.6004/jnccn.2025.7266","DOIUrl":"10.6004/jnccn.2025.7266","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 3.5","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EPR26-153: Cultural and Perceptual Factors Influencing Stool-DNA (mt-sDNA) Test Acceptability Among Foreign-Born Hispanic Patients of an Urban Midwestern Federally Qualified Health Center.","authors":"Ysaith Orellana Ascencio, A Michelle Corbett, Allison Antoine, Carrie Stehman, Elissa Sprecher, Noelle LoConte","doi":"10.6004/jnccn.2025.7466","DOIUrl":"10.6004/jnccn.2025.7466","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 3.5","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BPI26-013: Methodological Quality Assessment of Oncology Clinical Practice Guidelines for Cancer Treatment in Peru.","authors":"Karina Aliaga, Claudia Apolitano, Johanny Muro, Fradis Gil, Dante Baldeón, Carlos Salazar","doi":"10.6004/jnccn.2025.7364","DOIUrl":"10.6004/jnccn.2025.7364","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 3.5","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EPR26-164: Spatial Access to Mammography in Texas Appears Adequate, Yet Screening Remains Low.","authors":"Baihui Zhao, Sean G Young","doi":"10.6004/jnccn.2025.7327","DOIUrl":"10.6004/jnccn.2025.7327","url":null,"abstract":"","PeriodicalId":520697,"journal":{"name":"Journal of the National Comprehensive Cancer Network : JNCCN","volume":"24 3.5","pages":""},"PeriodicalIF":16.4,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}