Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation最新文献

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Dietary Knowledge, Health Belief, and Practice Among Hemodialysis Patients: A Structural Equation Modeling Study. 血液透析患者饮食知识、健康信念与实践:结构方程模型研究。
IF 3.2
Zhiqian Chen, Weiwei Zhao, Yuan Zhang, Na Xu, Li Luo, Shuqing Yin, Guanghui Xiao, Qun Liu, Chunyan Su
{"title":"Dietary Knowledge, Health Belief, and Practice Among Hemodialysis Patients: A Structural Equation Modeling Study.","authors":"Zhiqian Chen, Weiwei Zhao, Yuan Zhang, Na Xu, Li Luo, Shuqing Yin, Guanghui Xiao, Qun Liu, Chunyan Su","doi":"10.1053/j.jrn.2026.04.007","DOIUrl":"10.1053/j.jrn.2026.04.007","url":null,"abstract":"<p><strong>Objectives: </strong>To develop a structural equation model to investigate the correlation between dietary knowledge, health belief, and practice in hemodialysis patients.</p><p><strong>Methods: </strong>A multicenter cross-sectional study was conducted with 558 hemodialysis patients. The dietary knowledge and practice questionnaire and the dietary health belief questionnaire (including perceived susceptibility, perceived severity, perceived benefits, perceived barriers, and self-efficacy) in hemodialysis patients were used to collect data. Multiple linear regression analysis was used to explore the independent influencing factors of dietary practice scores. Structural equation modeling was utilized to analyze the relationships between dietary knowledge, health belief, and practice in hemodialysis patients.</p><p><strong>Results: </strong>Multiple linear regression analysis suggested that female gender (β = 0.147, P < .001), lower perceived susceptibility score (β = -0.103, P = .021), higher perceived benefits scores (β = 0.230, P < .001), lower perceived barriers scores (β = -0.118, P = .007), and higher self-efficacy scores (β = 0.253, P < .001) were associated with a higher dietary practice score. The structural equation model showed significant relationships between dietary knowledge and perceived severity (β = 0.736, P = .002), perceived benefits (β = 0.858, P = .001), and self-efficacy (β = 0.433, P = .001). Dietary practice was significantly linked to perceived barriers (β = -0.184, P = .001). The R<sup>2</sup> value for dietary practice in the structural equation model was 22.6%.</p><p><strong>Conclusions: </strong>Dietary educational interventions should focus on boosting self-efficacy and perceived benefits while minimizing perceived barriers to enhance dietary adherence in dialysis patients.</p>","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147794606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Body Mass Index and Survival in Individuals on Hemodialysis. 血液透析患者体重指数与生存的关系
IF 3.2
Cleodice Alves Martins, Leticia de Paiva Souza Klippel, Karen Dos Santos Barbosa, Larissa Vitória Batista Leandro, Júlia Rabelo Santos Ferreira, Elane Viana Hortegal Furtado, Camila Bruneli do Prado, Monica Cattafesta, Fabiano Kenji Haraguchi, Alexandre Cardoso da Cunha, Ana Cristina de Oliveira Soares, Edson Theodoro Dos Santos Neto, Luciane Bresciani Salaroli
{"title":"Association Between Body Mass Index and Survival in Individuals on Hemodialysis.","authors":"Cleodice Alves Martins, Leticia de Paiva Souza Klippel, Karen Dos Santos Barbosa, Larissa Vitória Batista Leandro, Júlia Rabelo Santos Ferreira, Elane Viana Hortegal Furtado, Camila Bruneli do Prado, Monica Cattafesta, Fabiano Kenji Haraguchi, Alexandre Cardoso da Cunha, Ana Cristina de Oliveira Soares, Edson Theodoro Dos Santos Neto, Luciane Bresciani Salaroli","doi":"10.1053/j.jrn.2026.04.008","DOIUrl":"10.1053/j.jrn.2026.04.008","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze the effects of body mass index (BMI) on all-cause and cardiovascular mortality in individuals undergoing hemodialysis.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed sociodemographic, clinical, and nutritional data from 953 patients with chronic kidney disease on hemodialysis and linked to death records from the Brazilian Mortality Information System (2019-2022). Kaplan-Meier survival curves and the log-rank tests were used to compare BMI and age groups. The Cox regression model was applied to assess the simultaneous effects of age, sex, time since diagnosis, education, smoking, and BMI on mortality.</p><p><strong>Results: </strong>Individuals with normal BMI had greater survival, with significantly higher survival curves over time, especially among adults and the elderly, compared to other BMI categories. Overweight adults and older adults showed shorter survival. When evaluating the covariates, the category of those who had never smoked showed an association with a protective effect against the risk of death (P = .0239), indicating that people who had never smoked had a 38.4% reduction in the risk of death compared to the reference group (former smokers). And those with \"more than 11 years of schooling\" showed a 61.7% reduction in the risk of death (P = .0467).</p><p><strong>Conclusions: </strong>Individuals on hemodialysis with a BMI in a normal state have greater survival, highlighting the importance of individualized interventions to improve the prognosis and quality of life of these individuals, taking into account nutritional status and sociodemographic factors.</p>","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diet Quality and Diversity According to Ultra-Processed Food Consumption in Nondialytic Chronic Kidney Disease: A Cross-Sectional Study. 非透析性慢性肾病患者超加工食品消费的饮食质量和多样性:一项横断面研究
IF 3.2
Amanda Goulart de Oliveira Sousa, Hellen Christina Neves Rodrigues, Luciana Bronzi de Souza, Mariana Ferreira Dos Santos, Nara Aline Costa, Maria do Rosário Gondim Peixoto
{"title":"Diet Quality and Diversity According to Ultra-Processed Food Consumption in Nondialytic Chronic Kidney Disease: A Cross-Sectional Study.","authors":"Amanda Goulart de Oliveira Sousa, Hellen Christina Neves Rodrigues, Luciana Bronzi de Souza, Mariana Ferreira Dos Santos, Nara Aline Costa, Maria do Rosário Gondim Peixoto","doi":"10.1053/j.jrn.2026.04.006","DOIUrl":"10.1053/j.jrn.2026.04.006","url":null,"abstract":"<p><strong>Objectives: </strong>To assess dietary quality and diversity according to ultra-processed food (UPF) consumption, focusing on mineral content in nondialysis chronic kidney disease (CKD) patients (stages 3-5).</p><p><strong>Methods: </strong>A cross-sectional study of 171 individuals from a capital city located in central Brazil, with 52.5% male participants, aged 65 (57-71) years, in stages 3-5, with an estimated glomerular filtration rate of 28.4 (19.0-39.2) mL/min/1.73 m<sup>2</sup>. Dietary intake was assessed using 24-hour recalls, and foods were classified by the NOVA system. Diet quality was evaluated using the Dietary Approaches to Stop Hypertension (DASH) score, and dietary diversity by the consumption of 13 unprocessed food subgroups. Participants were grouped into UPF consumption tertiles.</p><p><strong>Results: </strong>The mean proportion of UPF intake was 6.7% (g/d), reaching 17.2% in the highest tertile. Participants in the highest UPF consumption tertile had higher energy intake (P < .001), saturated fat (P < .001), sodium (P = .004), and phosphorus (P < .001), lower fiber intake (P < .001), and worse diet quality according to the DASH score. In adjusted analyses, higher UPF consumption was associated with a lower DASH score [β = -2.63; 95%, confidence interval: - 4.13 to -1.13; P < .001]. No differences were observed between UPF tertiles for dietary diversity and carbohydrate, protein, total fat, magnesium, and potassium intake.</p><p><strong>Conclusions: </strong>Even at relatively low levels, UPF intake negatively affected dietary composition and quality among nondialysis CKD patients, underscoring the need to limit UPF in CKD dietary guidelines and patient education.</p>","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147794608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, Correlates, and Outcomes of Absolute and Functional Iron Deficiency Anemia in Peritoneal Dialysis: A Single-Center Long-Term Cohort Study. 腹膜透析患者绝对缺铁性和功能性缺铁性贫血的患病率、相关性和结局:一项单中心长期队列研究
IF 3.2
Xiangwen Diao, Zhiwei Zheng, Jianxiong Lin, Xilong Mo, Haishan Wu, Yangyang Xin, Jing Guo, Cuixia Zhan, Wei Chen, Xiao Yang
{"title":"Prevalence, Correlates, and Outcomes of Absolute and Functional Iron Deficiency Anemia in Peritoneal Dialysis: A Single-Center Long-Term Cohort Study.","authors":"Xiangwen Diao, Zhiwei Zheng, Jianxiong Lin, Xilong Mo, Haishan Wu, Yangyang Xin, Jing Guo, Cuixia Zhan, Wei Chen, Xiao Yang","doi":"10.1053/j.jrn.2026.04.003","DOIUrl":"10.1053/j.jrn.2026.04.003","url":null,"abstract":"<p><strong>Objective: </strong>Iron deficiency anemia (IDA) correlates with an increased risk of adverse cardiovascular outcomes and mortality in chronic kidney disease. Its prevalence and prognostic implications in peritoneal dialysis (PD) populations remain underexplored.</p><p><strong>Methods: </strong>This single-center cohort included 2,121 PD patients (2009-2023) followed until 2024 and stratified by iron deficiency (ID) status: non-ID anemia, absolute IDA (transferrin saturation [TSAT] <20% + ferritin <100 ng/mL), functional IDA (FID, TSAT <20% + ferritin 100-500 ng/mL), and high-risk FID (TSAT <20% + ferritin >500 ng/mL). Multivariable logistic regression and Cox models were employed.</p><p><strong>Results: </strong>The cohort (59.5% male; mean age 45.2 ± 14.3 years) demonstrated 72.4% anemia prevalence, comprising non-ID anemia (29.7%), absolute IDA (22.9%), functional IDA (16.4%), and high-risk FID (3.4%). Independent anemia associated factors included female sex (odds ratio [OR] = 1.29), reduced estimated glomerular filtration rate (OR = 0.93), hypoalbuminemia (OR = 2.19), and elevated high-sensitivity C-reactive protein (OR = 1.68). During a median follow-up of 1,389 ± 941 days, 425 patients (20.0%) died, including 220 (10.4%) from cardiovascular events. High-risk FID independently predicted all-cause mortality (hazard ratio= 1.94, P= .005) and cardiovascular mortality (hazard ratio= 1.98, P= .037) after full adjustment.</p><p><strong>Conclusions: </strong>Functional IDA with ferritin >500 ng/mL exhibits distinct clinical features and is strongly related to high mortality in PD patients, underscoring urgent need for targeted therapeutic strategies.</p>","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of a Low-PRAL Modified New Nordic Renal Diet on Acid-Base Status in Patients With Stage 4-5 Chronic Kidney Disease and Chronic Metabolic Acidosis. 低pral改良新北欧肾饮食对4-5期慢性肾病合并慢性代谢性酸中毒患者酸碱状态的影响
IF 3.2
Anna Elvina Wittendorff Pedersen, Amalie Quist Rousing, Peder Berg, Julie Friis Christensen, Henriette Watson Hansen, Linea Cecilie Brandi, Mads Vaarby Sørensen, Ditte Hansen, Lisbet Brandi, Jens Rikardt Andersen, Louise Salomo
{"title":"Effects of a Low-PRAL Modified New Nordic Renal Diet on Acid-Base Status in Patients With Stage 4-5 Chronic Kidney Disease and Chronic Metabolic Acidosis.","authors":"Anna Elvina Wittendorff Pedersen, Amalie Quist Rousing, Peder Berg, Julie Friis Christensen, Henriette Watson Hansen, Linea Cecilie Brandi, Mads Vaarby Sørensen, Ditte Hansen, Lisbet Brandi, Jens Rikardt Andersen, Louise Salomo","doi":"10.1053/j.jrn.2026.04.002","DOIUrl":"https://doi.org/10.1053/j.jrn.2026.04.002","url":null,"abstract":"<p><strong>Objective: </strong>Metabolic acidosis is a common complication in chronic kidney disease (CKD) and is associated with accelerated disease progression. Diets with a low potential renal acid load (PRAL) represent a promising non-pharmacological strategy to mitigate metabolic acidosis. The New Nordic Renal Diet (NNRD), a plant-focused, low-phosphorus diet, improves acid-base status in patients with CKD stage 3-4. This study evaluated the effects of a two-week, low-PRAL modified NNRD in patients with advanced CKD and chronic metabolic acidosis.</p><p><strong>Design and methods: </strong>Twelve patients with CKD stage 4-5 and metabolic acidosis completed a prospective, sequential dietary intervention consisting of three consecutive two-week periods: habitual diet (control), low-PRAL modified NNRD (intervention), and free-living follow-up without dietary guidance. The intervention consisted of individualized low-PRAL recipes. Fasting blood samples, 24-hour urine collections, and clinical measures were obtained throughout the study.</p><p><strong>Results: </strong>During the intervention, PRAL and net endogenous acid production decreased significantly (-17.2 mmol/day, 95% CI: -23.1 to -11.3 and -17.4, 95% CI: -23.3 to -11.3, respectively). No changes in plasma tCO<sub>2</sub> were observed. Net acid excretion decreased slightly (4.1 mmol/d, 95% CI: -8.2 to -0.1). Clinically meaningful reductions were noted in albuminuria (-22.1%, 95% CI: -32.3 to -10.4), and systolic blood pressure (-17 mmHg, 95% CI: -22 to -12).</p><p><strong>Conclusion: </strong>A two-week low-PRAL NNRD reduced dietary acid load but did not correct chronic metabolic acidosis in patients with CKD stage 4-5. This likely reflects severely diminished renal acid excretory capacity in late-stage CKD, where endogenous acid production still exceeds the renal capacity.</p>","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147719323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Prediction Models for Frailty in Maintenance Hemodialysis Patients: A Systematic Review and Critical Appraisal. 维持性血液透析患者虚弱的风险预测模型:系统回顾和关键评价。
IF 3.2
Lili Wang, Xingyu Lei, Na Li, Yuanyuan Song, Sannv Feng, Qin Wang, Juzi Wang
{"title":"Risk Prediction Models for Frailty in Maintenance Hemodialysis Patients: A Systematic Review and Critical Appraisal.","authors":"Lili Wang, Xingyu Lei, Na Li, Yuanyuan Song, Sannv Feng, Qin Wang, Juzi Wang","doi":"10.1053/j.jrn.2026.03.006","DOIUrl":"10.1053/j.jrn.2026.03.006","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to conduct a systematic review and critical appraisal of studies on maintenance hemodialysis (MHD) frailty risk prediction models.</p><p><strong>Methods: </strong>A systematic search was conducted up to November 5, 2024, in the PubMed, Web of Science, Cochrane Library, Scopus, ProQuest, Embase, Cumulative Index to Nursing and Allied Health Literature, China National Knowledge Infrastructure (CNKI), Wanfang Database, Chinese Scientific and Technical Journals Database (VIP), and China Biology Medicine Database (CBM) for published articles, and data were extracted according to the Critical Appraisal Checklist and the Critical Appraisal of Research Systems for Predictive Modeling data extraction form. The risk of bias (ROB) and applicability of the included studies were assessed using the Predictive Modeling Risk of Bias Assessment Tool.</p><p><strong>Results: </strong>An initial literature search of 2,578 articles was conducted, and screening resulted in the inclusion of 16 studies and 19 predictive models. A total of 18 models reported area under the curve for subject work characteristics ranging from 0.72 to 0.998, and eight models reported calibration using calibration plots and/or goodness-of-fit curves. The prevalence of MHD patients ranged from 14.5% to 59.57%. Age, serum albumin level, sex, Charlson comorbidity index, daily activity status, and Nutritional Risk Screening 2002 (NRS-2002) score were the most common predictors. All the studies had a high ROB, mainly owing to poor reporting of the outcome domain and analysis domain; five studies were of high concern regarding applicability.</p><p><strong>Conclusion: </strong>Although most included prediction models demonstrated acceptable discriminatory performance, the overall methodological quality and clinical applicability of existing studies remain suboptimal. Future multicenter studies with large-scale cohorts should adhere to both the Predictive Modeling Risk of Bias Assessment Tool and Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis guidelines to develop predictive models characterized by three critical attributes: robust clinical utility, minimized ROB, and scientific validity.</p>","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147535197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to the "Letter to the Editor: Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Microbiome and Metabolism". 对“致编辑的信:给CKD患者服用益生元可以改变他们的微生物组和代谢”的回应。
IF 3.2
Dominic S Raj, Bei Gao, Michael B Sohn, Christopher Brydges, Anvesha Srivastava, Hamid Rabb, Alfred K Cheung, Oliver Fiehn, Cynthia Kendrick, Jennifer J Gassman, Anam Tariq, Tamara Isakova, Linda F Fried, Myles Wolf, Kalani L Raphael, John P Middleton, Yoosif Abdalla
{"title":"Response to the \"Letter to the Editor: Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Microbiome and Metabolism\".","authors":"Dominic S Raj, Bei Gao, Michael B Sohn, Christopher Brydges, Anvesha Srivastava, Hamid Rabb, Alfred K Cheung, Oliver Fiehn, Cynthia Kendrick, Jennifer J Gassman, Anam Tariq, Tamara Isakova, Linda F Fried, Myles Wolf, Kalani L Raphael, John P Middleton, Yoosif Abdalla","doi":"10.1053/j.jrn.2026.02.010","DOIUrl":"10.1053/j.jrn.2026.02.010","url":null,"abstract":"","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147494965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor Regarding "Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Microbiome and Metabolism". 致编辑关于“给CKD患者服用益生元可改变其微生物组和代谢”的信。
IF 3.2
Kaiyang Xu, Yutong Qian, Chen Zhao
{"title":"Letter to the Editor Regarding \"Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Microbiome and Metabolism\".","authors":"Kaiyang Xu, Yutong Qian, Chen Zhao","doi":"10.1053/j.jrn.2026.01.010","DOIUrl":"10.1053/j.jrn.2026.01.010","url":null,"abstract":"","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147494967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Predictive Value of Time-Averaged Cumulative Magnesium on Survival of Maintenance Hemodialysis Patients. 时间平均累积镁对维持性血液透析患者生存的预测价值。
IF 3.2
Zhihui Ding, Wei Wang, Hong Zhu, Lijuan Yan, Tao Wang, Xiaohua Zhu, Xiaofeng Zhou, Chunlei Yao, Guang Yang
{"title":"The Predictive Value of Time-Averaged Cumulative Magnesium on Survival of Maintenance Hemodialysis Patients.","authors":"Zhihui Ding, Wei Wang, Hong Zhu, Lijuan Yan, Tao Wang, Xiaohua Zhu, Xiaofeng Zhou, Chunlei Yao, Guang Yang","doi":"10.1053/j.jrn.2026.01.006","DOIUrl":"10.1053/j.jrn.2026.01.006","url":null,"abstract":"<p><strong>Objectives: </strong>Magnesium (Mg) plays a critical role in determining survival outcomes for maintenance hemodialysis (MHD) patients. This study aimed to investigate the prognostic value of time-averaged cumulative magnesium (TAC-Mg) in this population.</p><p><strong>Methods: </strong>The present study retrospectively analyzed 279 eligible MHD patients enrolled in November 2018, collecting demographic data, quarterly predialysis biochemical profiles, and TAC-Mg calculated via standardized formulas. After 4 years of follow-up, multiple statistical approaches were employed to assess predictive value of TAC-Mg for all-cause mortality in MHD patients.</p><p><strong>Results: </strong>Compared to the high TAC-Mg group, patients in the low TAC-Mg group were older, had a higher proportion of smokers, and exhibited poorer nutritional status. Kaplan-Meier analysis revealed that MHD patients in the low TAC-Mg group had a 4.855-fold higher risk of all-cause mortality compared to the high TAC-Mg group. Multivariable linear regression and Cox proportional hazards models demonstrated that TAC-Mg independently predicted all-cause mortality outcomes after adjusting for age, nutritional status, serum potassium, and chronic kidney disease mineral bone disorder markers (per 1-standard deviation increase: hazard ratio = 0.636, [95% confidence interval 0.470-0.861], P = .003). Receiver Operating Characteristic Curve (ROC) curve analysis further confirmed the superior predictive value of TAC-Mg over single-point baseline serum Mg levels for all-cause mortality risk in this population. The cutoff value of TAC-Mg to predict all-cause mortality risk was ≤1.07 mmol/L.</p><p><strong>Conclusions: </strong>Low TAC-Mg independently predicts all-cause mortality risk in MHD patients. The prognostic value of TAC-Mg may surpass that of single-point baseline Mg measurements. TAC-Mg ≤1.07 mmol/L may be a clinical warning threshold for increased all-cause mortality risk in this population.</p>","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146121741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: "The Acute Effect of Dark Chocolate on Blood Pressure and Renal Hemodynamics as Assessed With Doppler Ultrasound in Healthy Volunteers". 致编辑的信:“健康志愿者用多普勒超声评估黑巧克力对血压和肾脏血流动力学的急性影响。”
IF 3.2
Mutee Ur Rehman, Muhamnmad Hammad Chola, Muhammad Salman
{"title":"Letter to the Editor: \"The Acute Effect of Dark Chocolate on Blood Pressure and Renal Hemodynamics as Assessed With Doppler Ultrasound in Healthy Volunteers\".","authors":"Mutee Ur Rehman, Muhamnmad Hammad Chola, Muhammad Salman","doi":"10.1053/j.jrn.2025.08.005","DOIUrl":"10.1053/j.jrn.2025.08.005","url":null,"abstract":"","PeriodicalId":520689,"journal":{"name":"Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145728212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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