{"title":"Treatment of subacute/chronic ECU tendinopathy using wrist arthroscopy and open surgical repair.","authors":"Young-Keun Lee","doi":"10.1177/23094990211067009","DOIUrl":"https://doi.org/10.1177/23094990211067009","url":null,"abstract":"<p><strong>Purpose: </strong>To report the arthroscopic and clinical findings of patients with extensor carpi ulnaris (ECU) tendinopathy treated with wrist arthroscopy and open surgical repair.</p><p><strong>Methods: </strong>We retrospectively reviewed the medical records of seven patients with chronic ECU tendinopathy who were treated with diagnostic wrist arthroscopy and open surgical repair between 2010 and 2017. Seven cases diagnosed with ECU tendinopathy had undergone open procedure for the ECU tendinopathy, as well as wrist arthroscopy in the same session. Any pathology of the triangular fibrocartilage complex (TFCC) diagnosed by wrist arthroscopy were treated simultaneously with open procedure for the ECU tendinopathy. The functional outcome was evaluated by comparing the preoperative and final follow-up values of range of motion (ROM), grip strength, visual analog scale (VAS) for pain, modified Mayo wrist score and quick disabilities of the arm, shoulder, and hand (DASH) score.</p><p><strong>Results: </strong>TFCC tears were identified in four patients of which repair was performed concomitantly. The average follow-up period was 39 months (range, 25-49 months). At the final follow-up, all the outcomes including average VAS score (6.4→1), the ROM (173→192°), quick DASH score (42.5→18.2), and modified Mayo wrist score (48.6→79.3) improved significantly.</p><p><strong>Conclusion: </strong>When treating patients with ECU tendinopathy, the possibility of TFCC combined injury should always be considered. If surgical treatment is planned, we suggest a wrist arthroscopy for more accurate diagnosis an intra-articular pathology, particularly for patients whose MRI findings suggest a degenerative tear or degeneration at the periphery of the TFCC. Additionally, if ECU and DRUJ stability is obtained by repair or reconstruction of the concurrent pathologies in the ECU subsheath, TFCC and other intra-articular structures, the results will be favorable.</p>","PeriodicalId":520682,"journal":{"name":"Journal of orthopaedic surgery (Hong Kong)","volume":" ","pages":"23094990211067009"},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39787142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Necip Güven, Sezai Özkan, Tulin Turkozu, Adem Yokus, Cihan Adanas, Mehmet Ata Gokalp, Abbas Tokyay
{"title":"Insall-Salvati index is associated with anterior cruciate ligament tears in men: A Case-controlled study.","authors":"Necip Güven, Sezai Özkan, Tulin Turkozu, Adem Yokus, Cihan Adanas, Mehmet Ata Gokalp, Abbas Tokyay","doi":"10.1177/23094990211069692","DOIUrl":"https://doi.org/10.1177/23094990211069692","url":null,"abstract":"<p><strong>Purpose: </strong>Many factors in the etiology of anterior cruciate ligament (ACL) tears, predisposing factors related to knee morphology have also been reported. This study aimed to determine whether the Insall-Salvati (IS) index, which measures patella height, is a predisposing risk factor for ACL tears.</p><p><strong>Methods: </strong>The IS index, patellar length (PL), and patellar tendon length (PTL) values of patients (study group) that underwent arthroscopic reconstruction for ACL tears obtained by preoperative magnetic resonance imaging (MRI) were compared with the index values in the preoperative MRIs of patients that underwent knee arthroscopy for reasons besides ACL tears. In addition, the anterior tibial translation (ATT) of both groups was also measured and compared on MRI images. The MRI findings of the subjects included in both study groups were arthroscopically confirmed.</p><p><strong>Results: </strong>The mean ages of the study group (n = 120) and control group (n = 90) were 29.1 ± 8.2 years and 31.8 ± 9.8 years, respectively. There was a statistically significant difference between the study and control groups in terms of the PL and PTL values (<i>p</i> = 0.016 and <i>p</i> = 0.001, respectively). The IS index was statistically significantly higher in the study group with ACL tears (<i>p</i> = 0.009). The ATT was 8.61 ± 4.68 mm in the study group and 3.80 ± 1.92 mm in the control group. The ATT results of both groups were evaluated, and it was found that the study group was significantly higher than the control group (<i>p</i> = 0.001).</p><p><strong>Conclusions: </strong>As a result of our current study, we observed higher IS index values in patients with ACL tears than in patients without ACL tears. It should be kept in mind that patella alta, which is associated with a high IS index as one of the factors of knee morphology associated with ACL tears, may play a role in the etiology of ACL tears.</p>","PeriodicalId":520682,"journal":{"name":"Journal of orthopaedic surgery (Hong Kong)","volume":" ","pages":"23094990211069692"},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39917068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ning Fan, Shuo Yuan, Yong Hai, Peng Du, Jian Li, Xiaochuan Kong, Wenyi Zhu, Yuzeng Liu, Lei Zang
{"title":"Identifying the potential role of IL-1β in the molecular mechanisms of disc degeneration using gene expression profiling and bioinformatics analysis.","authors":"Ning Fan, Shuo Yuan, Yong Hai, Peng Du, Jian Li, Xiaochuan Kong, Wenyi Zhu, Yuzeng Liu, Lei Zang","doi":"10.1177/23094990211068203","DOIUrl":"https://doi.org/10.1177/23094990211068203","url":null,"abstract":"<p><strong>Purpose: </strong>We performed a bioinformatics analysis to identify the key genes that were differentially expressed between degenerative intervertebral disc (IVD) cells with and without exposure to interleukin-1β and explore the related signaling pathways and interaction networks.</p><p><strong>Methods: </strong>The microarray data were downloaded from the Gene Expression Omnibus (27,494). Then, analyses of the gene ontology, signaling pathways, and interaction networks for the differentially expressed genes (DEGs) were conducted using tools including the Database for Annotation, Visualization, and Integrated Discovery, Metascape, Gene Set Enrichment Analysis, Search Tool for the Retrieval of Interacting Genes, Cytoscape, Venn method, and packages of the R computing language.</p><p><strong>Results: </strong>A total of 260 DEGs were identified, including 161 upregulated and 99 downregulated genes. Gene Ontology annotation analysis showed that these DEGs were mainly associated with the extracellular region, chemotaxis, taxis, cytokine activity, and cytokine receptor binding. A Kyoto Encyclopedia of Genes and Genomes signaling pathway analysis showed that these DEGs were mainly involved in the of cytokine-cytokine receptor interaction, rheumatoid arthritis, tumor necrosis factor signaling pathway, <i>Salmonella</i> infection, and chemokine signaling pathway. The interaction network analysis indicated that 10 hub genes, including CXCL8, CXCL1, CCL20, CXCL2, CXCL5, CXCL3, CXCL6, C3, PF4, and GPER1 may play key roles in IVD degeneration.</p><p><strong>Conclusions: </strong>Bioinformatic analysis showed that CXCL8 and other nine key genes may play a role in the development of disc degeneration induced by inflammatory reactions and can be used to identify potential target genes for therapeutic applications in IVD degeneration.</p>","PeriodicalId":520682,"journal":{"name":"Journal of orthopaedic surgery (Hong Kong)","volume":" ","pages":"23094990211068203"},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39943932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lei Zhang, Lujing Xiong, Siyuan He, Jiaju Liu, Xin Zhou, Xiaogao Tang, Shijie Fu, Guoyou Wang
{"title":"Classification and morphological parameters of the coracoid process in Chinese population.","authors":"Lei Zhang, Lujing Xiong, Siyuan He, Jiaju Liu, Xin Zhou, Xiaogao Tang, Shijie Fu, Guoyou Wang","doi":"10.1177/23094990211069694","DOIUrl":"https://doi.org/10.1177/23094990211069694","url":null,"abstract":"<p><strong>Introduction: </strong>The coracoid process is an important anatomical structure of the scapula, which can be used as a landmark in the diagnosis and treatment of scapula related diseases, such as acromioclavicular joint dislocation, anterior shoulder instability, and coracoid fractures. The aim of this study was to classify the coracoid process according to morphology and to measure the morphological parameters of the coracoid process.</p><p><strong>Materials and methods: </strong>A total of 377 dry and intact scapulae were collected and classified in terms of the connection between the shape of coracoid process and common things in life. The anatomical morphology and the position related to acromion and glenoid socket of the coracoid process were measured in each type by three independent researchers with a digital caliper. The measurements were averaged and recorded.</p><p><strong>Results: </strong>Based on obvious morphological features, five specific types of the coracoid process were described: Type I, Vertical 8-shape; Type II, Long stick shape; Type III, Short stick shape; Type IV, Water drop shape, and Type V, Wedge shape. Type I (30%) and Type III (29%) were more prevalent in China. The tip width of the coracoid process of Type IV was the shortest and significantly different compared to the other types (<i>p</i> <.05), contrary to the longest in Type V. The tip thickness of the coracoid process of Type I was the shortest and significantly different from the other types (<i>p</i> <.05).</p><p><strong>Conclusions: </strong>The coracoid process was classified into five types based on obvious morphological features. Knowing of morphological classification and anatomical parameters of different types of the coracoid process, to some extent, may be helpful to diagnose and treat the shoulder joint disease, such as acromioclavicular joint dislocation, anterior shoulder instability, and coracoid fractures, and to theoretically reduce postoperative complications.</p>","PeriodicalId":520682,"journal":{"name":"Journal of orthopaedic surgery (Hong Kong)","volume":" ","pages":"23094990211069694"},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39831211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous autologous bone marrow injections for delayed or non-union of bones.","authors":"Ashok K Singh, Amit Sinha","doi":"10.1177/230949901302100233","DOIUrl":"https://doi.org/10.1177/230949901302100233","url":null,"abstract":"1. Connolly JR, Shindell R. Percutaneous marrow injection for an ununited tibia. Nebr Med J 1986;71:105–7. 2. Connolly JF, Guse R, Tiedeman J, Dehne R. Autologous marrow injection as a substitute for operative grafting of tibial nonunions. Clin Orthop Relat Res 1991;266:259–70. 3. Galasso O, Mariconda M, Romano G, Capuano N, Romano L, Ianno B, et al. Expandable intramedullary nailing and platelet rich plasma to treat long bone non-unions. J Orthop Traumatol 2008;9:129–34. 4. Hakimi M, Jungbluth P, Thelen S, Betsch M, Linhart W, Flohe S, et al. Platelet-rich plasma combined with autologous cancellous bone: an alternative therapy for persistent non-union? [in German]. Unfallchirurg 2011;114:998–1006. 5. Griffin XL, Wallace D, Parsons N, Costa ML. Platelet rich therapies for long bone healing in adults. Cochrane Database Syst Rev 2012;7:CD009496. Authors’ reply Our responses to the queries raised are as follows: 1. Our rationale for this study was to emphasise the effectiveness of bone marrow injection for delayed/non-unions, prior to considering bone grafting. We showed that bone marrow injection worked for almost all long bones, including metacarpals. Three injections of low volume (~30 ml) were as effective as a large volume (100–150 ml) of one-off injection,1,2 and it does not dilute the concentration of osteoblasts. 2. Fracture non-unions of stable configurations were included. No or minimal mobility at the site of non-union was expected. Fractures that were very unstable or with angular deformity and shortening were excluded, as were open fractures and infected non-unions. Informed consent was obtained from each patient. 3. We were aware of the paper by Galasso et al.3 on platelet-rich plasma and the paper by Hakimi et al.4 about the supplementary role of plateletrich plasma with bone grafting for treatment of non-unions. The paper of Griffin et al.5 was not available at the time of acceptance of our paper. Despite that, studies on the use of platelet-rich plasma alone for treatment of non-unions remain limited. 4. Patients were followed up (at 4–6 weeks interval) radiographically and clinically to decide on the need to proceed to the 2nd and 3rd injections. 5. These were cases of atrophic non-union, where biology rather than mechanical instability at the fracture site was the reason for failed union. Hence, immobilising the fracture site (other than for comfort) was deemed unnecessary. Therefore, patients were allowed to mobilise as comfort allowed. 6. In our experience, bone marrow injections work well in atrophic non-unions where fracture biology was the reason for failed union. Hence, for unstable or hypertrophc non-unions they may not have any role. Fractures that are very unstable or with angular deformity and shortening constitute contraindications to this procedure.","PeriodicalId":520682,"journal":{"name":"Journal of orthopaedic surgery (Hong Kong)","volume":" ","pages":"267"},"PeriodicalIF":1.6,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/230949901302100233","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40253286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}