Journal of alternative and complementary medicine (New York, N.Y.)最新文献

{"title":"Effectiveness of an Osteopathic Abdominal Manual Intervention in Pain Thresholds, Lumbopelvic Mobility, and Posture in Women with Chronic Functional Constipation.","authors":"María José Martínez-Ochoa,&nbsp;Juan Carlos Fernández-Domínguez,&nbsp;Jose Miguel Morales-Asencio,&nbsp;Javier González-Iglesias,&nbsp;François Ricard,&nbsp;Ángel Oliva-Pascual-Vaca","doi":"10.1089/acm.2018.0081","DOIUrl":"https://doi.org/10.1089/acm.2018.0081","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the effect of an osteopathic abdominal manual intervention (AMI) on pressure pain thresholds (PPTs), mobility, hip flexibility, and posture in women with chronic functional constipation.</p><p><strong>Design: </strong>Randomized, double-blind placebo-controlled trial.</p><p><strong>Setting/location: </strong>Subjects were recruited for the study by referral from different gastroenterology outpatient clinics in the city of Madrid (Spain).</p><p><strong>Subjects: </strong>Sixty-two patients suffering from chronic functional constipation according to the guidelines of the Congress of Rome III.</p><p><strong>Interventions: </strong>The experimental group (n = 31) received an osteopathic AMI, and the control group (n = 31) received a sham procedure.</p><p><strong>Outcome measures: </strong>PPTs at different levels, including vertebral levels C7, T3, T10, T11, and T12, trunk flexion range of motion (ROM), hip flexibility, and posture, were measured before and immediately after the intervention. A comparison between the difference between the pre- and postintervention values using the Student's t test for independent samples or nonparametric U-Mann-Whitney test depending on the distribution normality of the analyzed variables was perfomed.</p><p><strong>Results: </strong>In the intergroup comparison, statistically significant differences were found in PPT at T11 (p = 0.011) and T12 (p = 0.001) and also in the trunk flexion ROM (p < 0.05). Moreover, women showed no adverse effects with acceptable pain tolerance to the intervention.</p><p><strong>Conclusion: </strong>The application of an osteopathic AMI is well tolerated and improves pain sensitivity in areas related to intestinal innervation, as well as lumbar flexion.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"816-824"},"PeriodicalIF":2.6,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2018.0081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40438276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Specifically Designed Multispecies Probiotic Supplement Relieves Seasonal Allergic Rhinitis Symptoms.","authors":"Annabelle M Watts,&nbsp;Amanda J Cox,&nbsp;Peter K Smith,&nbsp;Isolde Besseling-van der Vaart,&nbsp;Allan W Cripps,&nbsp;Nicholas P West","doi":"10.1089/acm.2017.0342","DOIUrl":"https://doi.org/10.1089/acm.2017.0342","url":null,"abstract":"<p><strong>Background: </strong>Probiotics are purported to reduce symptoms of allergic rhinitis. This study sought to determine the proportion of participants with an improvement in the mini Rhinoconjunctivitis Quality of Life Questionnaire (mRQLQ) in response to a multispecies probiotic supplement with a Simon Two-Stage design.</p><p><strong>Methods: </strong>This study was based on a Simon Two-Stage Design for p₁-p₀ = 0.18 to account for seasonal variation in symptoms. Under this design, ≥10 patients are required to exhibit an improvement in quality-of-life scores to determine that there was sufficient activity for the supplement to be considered effective. Participants consumed a probiotic supplement (Ecologic^® AllergyCare; probiotik^®pur) twice daily for 8 weeks. The primary outcome measure was based on a change in mRQLQ scores following supplementation. Secondary outcomes include assessment of change in symptoms and medication usage with a twice-weekly symptom and medication diary, nasal congestion by rhinomanometry, and total serum Immunoglobulin E (IgE) and specific IgE for Bermuda grass.</p><p><strong>Results: </strong>A total of 40 participants completed the study. A total of 25 participants (63%, 49-76%, p < 0.001; mean, 95% confidence interval, p-value) out of 40 participants had a clinically meaningful response to treatment based on assessment of mRQLQ. On average, mRQLQ scores changed from 2.83 ± 1.51 at baseline to 1.66 ± 1.36 at week 4 and 1. 38 ± 1.13 at week 8 (p < 0.01) (mean ± SD, p-value). Sum of individual symptom scores and overall symptom scores over the course of treatment was significantly reduced (p = 0.036 and p = 0.039, respectively). A moderate reduction in frequency of allergy-related medication use in the final 4 weeks of supplementation period was observed (52.5% weeks 0-4 to 41.4% weeks 4-8; average proportion of total diary responses, p = 0.085). The supplement was largely well tolerated by participants at the dose provided.</p><p><strong>Conclusions: </strong>The proportion of participants exhibiting improvement in quality-of-life metrics warrants continued investigation in the form of a phase III placebo-controlled trial.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"833-840"},"PeriodicalIF":2.6,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2017.0342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40529101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Multiple Roles of Acupuncture in Alleviating the Opioid Crisis.","authors":"Jiang-Ti Kong","doi":"10.1089/acm.2018.0083","DOIUrl":"https://doi.org/10.1089/acm.2018.0083","url":null,"abstract":"Note: This column continues our quarterly Turning Points series from the Society for Acupuncture Research (SAR). Author Jiang-Ti Kong, MD, a member of the Board of Directors of SAR, is a pain management specialist, anesthesiologist, and medical acupuncturist at Stanford University School of Medicine. In addition to teaching, research and a conventional pain management practice, Dr. Kong leads the acupuncture service at Stanford Pain Management Center. Her commentary was stimulated by a three pronged strategy on the opioid crisis authored by leaders of the USA National Institutes of Health (NIH) and National Institute on Drug Abuse (NIDA) published in October 2017 in the New England Journal of Medicine. — John Weeks, Editor-in-Chief","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"304-306"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2018.0083","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35982189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Australian Complementary Medicine Workforce: A Profile of 1,306 Practitioners from the PRACI Study.","authors":"Amie Steel,&nbsp;Matthew Leach,&nbsp;Jon Wardle,&nbsp;David Sibbritt,&nbsp;Janet Schloss,&nbsp;Helene Diezel,&nbsp;Jon Adams","doi":"10.1089/acm.2017.0206","DOIUrl":"https://doi.org/10.1089/acm.2017.0206","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to describe the Australian complementary medicine (CM) workforce, including practice and professional characteristics.</p><p><strong>Design: </strong>National cross-sectional survey.</p><p><strong>Settings/location: </strong>Australia.</p><p><strong>Subjects: </strong>Any individual who self-identified as a practitioner qualified in any one of 14 CM professions and working in any state or territory of Australia was eligible to participate in the survey.</p><p><strong>Interventions: </strong>A 19-item online survey was developed following a review of existing CM workforce data and in alignment with other CM workforce survey projects in progress at the time. The survey items were presented under three main constructs: demographic characteristics, professional characteristics, and practice characteristics.</p><p><strong>Statistical analysis: </strong>Descriptive statistical analysis, including frequencies and percentages, of multiple choice survey items was used. Open response items were analyzed to determine the mean, standard deviation (SD), minimum, and maximum. The demographic data were evaluated for representativeness based on previously reported CM workforce figures.</p><p><strong>Results: </strong>The survey was completed by 1306 CM practitioners and was found to be nationally representative compared with the most recent registrant data from the Chinese Medicine Board of Australia. Participants primarily practiced in the most populous Australian states and worked in at least one urban clinical location. Most participants held an Advanced Diploma qualification or lower, obtained their qualification ten more years ago, and practiced in a clinical environment alongside at least one other practitioner from another health profession. Participants reported diverse clinical practice specialties and occupational roles. Per week, participants worked an average of 3.7 days and treated 23.6 clients.</p><p><strong>Conclusions: </strong>The results from this survey of practitioners from most complementary professions in Australia provide new insights into the national complementary medicine workforce. Further exploration of the CM workforce is warranted to inform all who provide patient care and develop health policy for better patient and public health outcomes.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"385-394"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2017.0206","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35701230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reemergence of Blended Tube Feeding and Parent's Reported Experiences in Their Tube Fed Children.","authors":"Teresa W Johnson,&nbsp;Amy L Spurlock,&nbsp;Lisa Epp,&nbsp;Ryan T Hurt,&nbsp;Manpreet S Mundi","doi":"10.1089/acm.2017.0134","DOIUrl":"https://doi.org/10.1089/acm.2017.0134","url":null,"abstract":"<p><strong>Objective: </strong>Healthcare providers (HCPs) report increased interest in blenderized tube feeding (BTF) as an alternative to commercial formula (CF) feeding-particularly in families of tube fed children. The objective of this study was to explore parents' reported experiences of CF and BTF in their children.</p><p><strong>Design: </strong>Prospective descriptive study utilizing a convenience sample.</p><p><strong>Setting/subjects: </strong>Parents (n = 433) of tube fed children in an online tube feeding support group completed an electronic survey to compare experiences of CF and BTF in their tube fed children.</p><p><strong>Results: </strong>The sample was evenly represented by parents using CF (50.5%) and BTF (49.5%). Reasons parents chose BTF included desire to provide whole foods (20.2%), decrease symptoms of tube feeding intolerance (19.7%), provide family meals (12.2%), increase oral intake (10.8%), address allergies (5.3%), or because they did not like formula (19.7%). Parents reported fewer symptoms of tube feeding intolerance on BTF and their children more frequently met growth goals compared to formula feeding. Only half (49.3%) of parents using BTF referred to HCPs for recipes and feeding oversight. The primary reasons parents did not use BTF included lack of knowledge (50.9%) or time constraints (20.0%).</p><p><strong>Conclusions: </strong>A significant number of parents in this sample successfully provide full or partial BTF to their children but only half rely on HCPs for guidance. There is wide variability in BTF preparation and delivery. Parents who use or have interest in BTF need knowledgeable and supportive HCPs for guidance and follow-up due to the unique nutritional needs of this patient population. HCPs need to be prepared to screen families of tube fed children who are using BTF or are interested in this feeding alternative to CF. Healthcare facilities need to evaluate their enteral feeding policies to accommodate patients on BTF.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"369-373"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2017.0134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35649436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statutory Regulation of Traditional Medicine Practitioners and Practices: The Need for Distinct Policy Making Guidelines.","authors":"Nadine Ijaz,&nbsp;Heather Boon","doi":"10.1089/acm.2017.0346","DOIUrl":"https://doi.org/10.1089/acm.2017.0346","url":null,"abstract":"<p><p>The World Health Organization (WHO) has called for the increased statutory regulation of traditional and complementary medicine practitioners and practices, currently implemented in about half of nations surveyed. According to recent WHO data, however, the absence of policy guidelines in this area represents a significant barrier to implementation of such professional regulations. This commentary reviews several key challenges that distinguish the statutory regulation of traditional medicine practitioners and practices from biomedical professional regulation, providing a foundation for the development of policy making parameters in this area. Foremost in this regard are the ongoing impacts of the European colonial encounter, which reinforce biomedicine's disproportionate political dominance across the globe despite traditional medicine's ongoing widespread use (particularly in the global South). In this light, the authors discuss the conceptual and historical underpinnings of contemporary professional regulatory structures, the tensions between institutional and informal traditional medicine training pathways, and the policy challenges presented by the prospect of standardizing internally diverse indigenous healing approaches. Epistemic and evidentiary tensions, as well as the policy complexities surrounding the intersection of cultural and clinical considerations, present additional challenges to regulators. Conceptualizing professional regulation as an intellectual property claim under the law, the authors further consider what it means to protect traditional knowledge and prevent misappropriation in this context. Overall, the authors propose that innovative professional regulatory approaches are needed in this area to address safety, quality of care, and accessibility as key public interest concerns, while prioritizing the redress of historical inequities, protection of diverse indigenous knowledges, and delivery of care to underserved populations.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"307-313"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2017.0346","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35758184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colonialism, Health Justice, and (Re)Examination of the Value of Traditional Practitioners and Licensed Integrative Health Professionals.","authors":"John Weeks","doi":"10.1089/acm.2018.29046.jjw","DOIUrl":"https://doi.org/10.1089/acm.2018.29046.jjw","url":null,"abstract":"","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"301-303"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2018.29046.jjw","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35995749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Goiter with Traditional Chinese Medicine Regimen Xing Qi Hua Ying Tang: A Clinical Study on 72 Patients with Multinodular and Diffuse Goiter.","authors":"Ming-Li Yang,&nbsp;Bo Lu","doi":"10.1089/acm.2017.0138","DOIUrl":"https://doi.org/10.1089/acm.2017.0138","url":null,"abstract":"<p><strong>Objective: </strong>The present work aimed to further explore the therapeutic potential of Xing Qi Hua Ying Tang (XQHYT) by conducting a systemic clinical study in patients with goiter.</p><p><strong>Design: </strong>Seventy-two patients with either multinodular or diffuse goiter were enrolled and randomly assigned into treatment group receiving XQHYT (n = 36) and control group receiving Hai Zao Yu Hu Tang (n = 36).</p><p><strong>Location: </strong>Traditional Chinese Medicine Hospital of Shanxi.</p><p><strong>Subjects: </strong>Patients were diagnosed multinodular goiter or diffuse goiter resulting from Qi stagnation.</p><p><strong>Intervention: </strong>All patients took the extract twice a day (100 mL each time) for two courses of treatment, of which a single course lasted for 3 months. Before the treatment was commenced and after the completion of the treatment, general body checks, thyroid function test, and goiter size examination were performed.</p><p><strong>Outcome measures: </strong>Scoring of the clinical symptoms using Chinese medicine symptomatology was also done.</p><p><strong>Results: </strong>The symptom score of the treatment group was significantly lower than that of the control group (treatment group, 8.26 ± 2.62; control group, 10.02 ± 2.62; p < 0.05). Substantial reduction in goiter size was seen in 82.3% of XQHYT-treated patients, whereas in the control group only 67.7% of patients exhibited constricted goiter. When assessed by both the Chinese medicine criteria and goiter size, the overall effective rate of the treatment group was 91.2%, whereas that of the control group was only 67.7%. The difference was statistically significant (p < 0.05). XQHYT did not affect the normal functions of liver, kidney, and heart. For both groups of patients, their levels of thyroid-stimulating hormone, free T4 and free T3 were normal before the treatment, and were not affected by the treatment.</p><p><strong>Conclusion: </strong>XQHYT was shown to be a promising therapeutic regimen for the treatment of goiter. The herbal regimen ameliorated clinical symptoms of patients that were accompanied with reduction in the size of goiter.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"374-377"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2017.0138","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35625433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review Study on the Beneficial Effects of Baduanjin.","authors":"Liye Zou,&nbsp;Zhujun Pan,&nbsp;Albert Yeung,&nbsp;Saira Talwar,&nbsp;Chaoyi Wang,&nbsp;Yang Liu,&nbsp;Yankai Shu,&nbsp;Xiaoan Chen,&nbsp;Garrett Anthony Thomas","doi":"10.1089/acm.2017.0241","DOIUrl":"https://doi.org/10.1089/acm.2017.0241","url":null,"abstract":"<p><strong>Aim: </strong>Baduanjin, a Chinese traditional Qigong exercise that focuses on a mind-body integration, is considered to be an effective exercise in promoting health. Thus, we systematically and critically evaluated the emerging literature relating to the effects of Baduanjin on health outcomes.</p><p><strong>Methods: </strong>We used seven English-language electronic databases for the literature search. At least one health-related parameter was reported in retrievable full-text Baduanjin intervention studies.</p><p><strong>Results: </strong>A total of 22 eligible studies were included. The inter-rater reliability between two review authors was 94.4% for selecting eligible studies. The results of individual studies support the notion that Baduanjin may be effective as an adjunctive rehabilitation method for improving cognitive functions in addition to psychological and physiological parameters among different age groups and various clinical populations (e.g., Parkinson's disease, chronic neck pain, chronic fatigue syndrome-like illness, psychological illness).</p><p><strong>Conclusion: </strong>Before we draw a definitive conclusion relating to Baduanjin for health benefits, more methodologically rigorous studies with a long-term follow-up assessment should be further conducted to examine the effects of Baduanjin on health-related parameters and disease-specific measures in different health conditions. This review lends insight for future studies on Baduanjin and its potential application in preventive medicine and rehabilitation science.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"324-335"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2017.0241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35329118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibromyalgia with Gabapentin and Osteopathic Manipulative Medicine: A Pilot Study.","authors":"Cynthia Marske,&nbsp;Natasha Bernard,&nbsp;Alison Palacios,&nbsp;Cary Wheeler,&nbsp;Ben Preiss,&nbsp;Mackenzie Brown,&nbsp;Saveri Bhattacharya,&nbsp;Gloria Klapstein","doi":"10.1089/acm.2017.0178","DOIUrl":"https://doi.org/10.1089/acm.2017.0178","url":null,"abstract":"<p><strong>Objectives: </strong>This pilot study compares the safety and efficacy of three treatments in reducing pain and improving fibromyalgia symptoms.</p><p><strong>Design: </strong>This study was an 8-week prospective, single center feasibility study.</p><p><strong>Setting and subjects: </strong>Forty subjects were recruited from Solano, Sonoma, and Contra Costa counties of California in 2006-2009. Subjects were aged 18-65 and met the American College of Rheumatology (ACR) 1990 criteria for fibromyalgia.</p><p><strong>Interventions: </strong>This study had three treatment arms: gabapentin only (900 mg/day), osteopathic manipulative medicine (OMM) only, and combined treatment of gabapentin plus OMM. OMM treatment was administered by advanced medical students for 30 min, once a week. The trial lasted for 8 weeks, which included 6 weeks of treatment plus initial and final visits.</p><p><strong>Outcome measures: </strong>Key outcome measures included Wong-Baker FACES Pain Rating Scale (WBF), Clinical Global Impression of Health (CGI), Fibromyalgia Impact Questionnaire (FIQ), and number of tender points.</p><p><strong>Results: </strong>Twenty-nine subjects completed the trial; 8 subjects received gabapentin only, 11 patients received OMM only, and 10 patients received gabapentin plus OMM. Subjects receiving OMM alone and subjects receiving the combined treatment of OMM and gabapentin displayed clinical improvements based on WBF (p < 0.01 and p = 0.03, respectively), while the change among the gabapentin-only group was nonsignificant. The OMM only group was the only group to experience a significant decline in CGI scale (p < 0.01). No statistically significant changes were observed with the FIQ or number of tender points. No differences across groups were statistically significant. This is to be expected in a feasibility study with a small sample size.</p><p><strong>Conclusions: </strong>This pilot study suggests that OMM treatment and gabapentin are safe and clinically efficacious treatment of pain and other constitutional and somatic symptoms associated with fibromyalgia. A larger trial using the new ACR 2010 Fibromyalgia criteria is needed to confirm these findings.</p>","PeriodicalId":520659,"journal":{"name":"Journal of alternative and complementary medicine (New York, N.Y.)","volume":" ","pages":"395-402"},"PeriodicalIF":2.6,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/acm.2017.0178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35705130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}