European psychiatry : the journal of the Association of European Psychiatrists最新文献

{"title":"Effects of childhood maltreatment on emotional intelligence and psychosocial functioning in adult euthymic bipolar disorder patients compared with healthy controls.","authors":"Elisabet Vilella, Maite Royo-Iglesias, Selena Aranda, Cristina Varo, Esther Jiménez, Alfonso Gutiérrez-Zotes, Sílvia Alonso-Lana, Salvador Sarró, Jose Sánchez-Moreno, Natalia E Fares-Otero, Joaquin Ruiz, Norma Verdolini, Edith Pomarol-Clotet, Eduard Vieta","doi":"10.1192/j.eurpsy.2026.12251","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12251","url":null,"abstract":"<p><strong>Background: </strong>Childhood maltreatment (CM) has been linked to poor emotional intelligence (EI) and psychosocial functioning (PSF) in patients with bipolar disorder (BD). However, no study has investigated whether EI mediates the relationship between CM and PSF in patients with BD. Here, we aimed to assess the association of CM with EI and PSF in euthymic patients with BD compared with healthy controls (HCs).</p><p><strong>Methods: </strong>We assessed 124 euthymic participants with a BD diagnosis and 124 HCs by means of the Mayer-Salovey-Caruso Emotional Intelligence Test, the Functioning Assessment Short Test and the Childhood Trauma Questionnaire. Linear regression models were constructed using CM categorized as no-CM, low/moderate-CM and high-CM. We subsequently assessed whether EI mediates the relationship between CM and PSF.</p><p><strong>Results: </strong>Compared with HCs, patients with BD reported higher rates of CM and lower rates of PSF and EI. In the BD group, subjects who exhibited low/moderate CM obtained lower levels of PSF and EI than those with no-CM and high-CM levels. The regression models demonstrated that, compared with the no-CM category, the low/moderate CM category was inversely associated with EI strategic area scores in patients with BD. However, EI did not mediate the relationship between CM and PSF.</p><p><strong>Conclusions: </strong>Low/moderate-CM was associated with the worst EI scores in BD. However, we did not observe any mediating effect of EI on the relationship between CM and PSF. Our results emphasize the importance of assessing CM in mental health and suggest that targeted therapies should be administered to affected patients.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e106"},"PeriodicalIF":6.7,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149248386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"European psychiatrists' approaches to the treatment of bipolar disorder.","authors":"Gabriele Sani, Martina Rojnic Kuzman, Pavel Mohr, Goran Koletic, Celso Arango, Koray Başar, Simavi Vahip, Oleg Skugarevsky, Tihana Jendričko, Stojan Bajraktarov, Goran Mihajlović, Māris Taube, Geert Dom, Kirsten Catthoor, Jana Chihai, Philippe Courtet, Doina Constanta Maria Cosman, Egor Chumakov, Michai Patarák, Bernardo Carpiniello, Mario Pinto, Ana Popova, Ruslan Zhelev, Eka Chonia, Jerzy Samochowiec, Diogo Telles-Correia, Dragan Babić, Goran Račetović, Natalya Maruta, Andrea Fiorillo, Eduard Vieta","doi":"10.1192/j.eurpsy.2026.12265","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12265","url":null,"abstract":"<p><strong>Background: </strong>The European Psychiatric Association (EPA) undertook a study to investigate treatment preferences of European psychiatrists towards Bipolar Disorder (BD), as part of the Ambassador programme series of surveys.</p><p><strong>Methods: </strong>We conducted a cross-sectional online survey among psychiatrists and psychiatry trainees from 40 European countries. The questionnaire contained clinical vignettes of different phases of BD including manic, rapid cycling, mixed, hypomanic, and depressive episodes, for both initial and subsequent treatment strategies.</p><p><strong>Results: </strong>The final sample consisted of 654 participants, from Central and Eastern Europe (CEE), Southern Europe (SE), Northern Europe (NE), and Western Europe (WE). The majority preferred pharmacotherapy, most commonly as a combination of two or three drugs to treat all phases of the BD, with lithium being the most preferred option in all phases.Among antipsychotics, olanzapine and quetiapine were the most commonly chosen. Antidepressants were applied in almost 20% of responses for the depressive phase. Psychosocial interventions were not systematically implemented, particularly during manic and mixed episodes, but when recommended, the most common approaches included psychoeducation, cognitive behavioural therapy (CBT) in up to 40% in depressive phase, and lifestyle recommendations. However, latent class analysis identified four different classes of prescribers.</p><p><strong>Conclusions: </strong>Psychiatrists showed broadly similar pharmacological treatment preferences for BD, with frequent use of lithium-based combination therapies and limited implementation of psychosocial interventions, although latent class analysis revealed distinct prescribing profiles. These findings support the need for enhanced dissemination of evidence-based guidelines and greater integration of psychosocial approaches in BD care.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e105"},"PeriodicalIF":6.7,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149241102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public mental health: The case and required actions across the European region.","authors":"Jonathan Campion, Celso Arango, Geert Dom, Guilio Castelpietra, Koray Başar, Annabel S Mueller-Stierlin, Mariana Pinto da Costa, Andrea Fiorillo","doi":"10.1192/j.eurpsy.2026.12239","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12239","url":null,"abstract":"<p><p>Despite the existence of effective public mental health (PMH) interventions, only a minority across the European region receive treatment for mental health conditions (MHCs). Even fewer receive interventions to prevent MHC-associated impacts, with negligible coverage of interventions to prevent MHCs, or promote mental well-being and resilience. Various reasons account for implementation failure which breaches the right to health and results in population scale preventable suffering, broad impacts and associated economic costs. Public mental health involves a population approach to improve coverage, outcomes and coordination of PMH interventions. Required actions to scale up PMH implementation include effectively making the case through assessment of PMH need, highlighting economic impacts of PMH implementation failure and improved coverage, and coordinated advocacy and leadership. Public mental health practice involves the use of PMH needs assessment to inform choice of interventions, policy development, and required coverage and resources for effective PMH intervention delivery by different sectors. This is supported by the collection of PMH-relevant data. Further actions to scale up PMH implementation include adopting human rights-based approaches and legislation, PMH training to different sectors and improved population PMH literacy, maximizing existing resources, settings-based and integrated approaches, use of digital technology, prioritizing interventions with large population impact, and implementation-focused research. Scaled up PMH implementation results in broad population impacts, achievement of a range of policy objectives, sustainable reduction in impacts of MHCs and promotion of mental well-being across the population of the European region. Associated economic savings also make PMH practice an essential part of sustainable economic development.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e104"},"PeriodicalIF":6.7,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149231361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing the use of artificial intelligence in psychiatry: The need for international collaboration.","authors":"Jack Healy, Ben Bond, Lorenzo Ghelfi, Sudipto Das, Conor Gavin, Philipp Homan, Iris Sommer, David Cotter, Mary Cannon, John Lyne","doi":"10.1192/j.eurpsy.2026.12258","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12258","url":null,"abstract":"<p><p>Challenging macrotrends in recent decades have characterised population mental health across the globe, with apparent deterioration in adolescent mental health, as well as underfunded, inequitable, and inefficient psychiatric care systems [1]. Unnecessary delays to treatment are widespread, with systemic difficulties, such as clinician burnout, a dearth of funding, and staff shortages, negatively impacting mental health care across Europe and beyond [2]. With limited clinician time and resources available, new methods for improving mental health care are an urgent priority. Digital technologies, and particularly recent advances in the capabilities of artificial intelligence (AI), offer potential to address some of these challenges, thereby transforming approaches to mental health care.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e103"},"PeriodicalIF":6.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence EEG biomarkers for schizophrenia diagnosis: Systematic review with PROBAST+AI assessment.","authors":"Kacper Łoś, Napoleon Waszkiewicz","doi":"10.1192/j.eurpsy.2026.12262","DOIUrl":"10.1192/j.eurpsy.2026.12262","url":null,"abstract":"<p><strong>Background: </strong>The application of artificial intelligence (AI) to resting-state electroencephalography (EEG) data represents a burgeoning frontier in schizophrenia diagnostics. However, the inferential validity of findings is frequently compromised by methodological heterogeneity. This systematic review rigorously evaluates the diagnostic efficacy and methodological robustness of AI-generated EEG biomarkers by implementing the Prediction model Risk Of Bias Assessment Tool for Artificial Intelligence (PROBAST+AI).</p><p><strong>Methods: </strong>Following PRISMA guidelines, a systematic search of PubMed, Scopus, and Web of Science identified 43 primary studies encompassing 3,420 patients with schizophrenia or first-episode psychosis and 3,164 healthy controls (total <i>N</i> = 6,584). Methodological quality and validation strategies were assessed using the 34 signaling questions of the PROBAST+AI framework.</p><p><strong>Results: </strong>The aggregate mean diagnostic accuracy across the literature was 93.38%, with deep learning architectures demonstrating superior metrics relative to classical machine learning (96.83% vs. 87.68%). Critically, external validation was restricted to 4.7% of the included studies. A pronounced performance discrepancy was observed between subject-wise (88.22%) and segment-wise (98.14%) validation protocols, indicating pervasive data leakage. Overall, 76.7% of the analyzed studies were characterized by a high risk of bias, predominantly stemming from suboptimal data partitioning and inadequate independent verification.</p><p><strong>Conclusions: </strong>Contemporary diagnostic accuracies appear to be artifactually elevated due to structural methodological deficiencies and data leakage. Consequently, current evidence does not support the immediate clinical implementation of AI-EEG biomarkers in schizophrenia. To facilitate translational progress, we propose a standardized methodological framework optimizing validation strategies.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e101"},"PeriodicalIF":6.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Undirected and directed networks of problem gambling: Follow the money trail.","authors":"André Syvertsen, Omid V Ebrahimi, Dominic Sagoe, Joakim H Kristensen, Ståle Pallesen","doi":"10.1192/j.eurpsy.2026.12261","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12261","url":null,"abstract":"<p><strong>Background: </strong>Psychometric network analysis offers a granular understanding of problem gambling (PG) by modeling individual symptoms within an interconnected system. Identifying central symptoms can help explain symptom co-occurrence and core symptoms relevant for escalating severity.</p><p><strong>Methods: </strong>We estimated undirected cross-sectional and directed cross-lagged network models based on four representative Norwegian population surveys (2013, 2015, 2019, and 2022; age range 16-74) and assessed network stability, accuracy, and generalizability. Cross-sectional samples ranged from <i>n</i> = 3,232 to 6,034 (47-50% women) and cross-lagged samples included <i>n</i> = 3,043 (2013-2015, 50% women) and <i>n</i> = 2,749 (2019-2022, 47% women). PG symptoms were measured with the Problem Gambling Severity Index alongside self-reported gambling expenditure.</p><p><strong>Results: </strong>Within undirected networks, financial problems showed the strongest strength centrality and these networks showed strong generalizability, including the 2019 and 2022 surveys per Network Comparison Test (<i>p</i> = .65), edge presence (φ = .79), and edge weight (<i>r</i> = .85) correlations. Within directed networks, borrowing money had the strongest association with symptoms at follow-up (out-strength), while guilt at follow-up was most strongly predicted by other symptoms (in-strength). Generalizability between the 2013-2015 and 2019-2022 networks was inconclusive, with low correlation in edge presence (φ = .08) and high correlation in edge weights (<i>r</i> = .74).</p><p><strong>Conclusions: </strong>Financial problems and borrowing money emerged as the most central PG symptoms in undirected and directed networks, respectively. Following further investigation, these symptoms may act as informative targets for screening, early intervention, and harm-reduction policy.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e100"},"PeriodicalIF":6.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shared genetic architecture between premenstrual disorder symptoms and major psychiatric disorders suggests a role for calcium signaling.","authors":"Piotr Jaholkowski, Elgeta Hysaj, Nadine Parker, Erik David Wiström, Elise M Koch, Pravesh Parekh, Susu Qu, Srdjan Djurovic, Olav Bjerkehagen Smeland, Marit Haram, Kevin Sean O'Connell, Donghao Lu, Alexey A Shadrin, Ole A Andreassen","doi":"10.1192/j.eurpsy.2026.12260","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12260","url":null,"abstract":"<p><strong>Background: </strong>Major psychiatric disorders (MPDs) and premenstrual disorders (PMDs) are often comorbid, with indications of shared genetic architecture. However, the specific genetic variants underlying this comorbidity remain elusive. The aim of this study was to identify genomic loci shared between MPDs and PMDs, and to assess the functional characteristics of genes mapped to these loci.</p><p><strong>Methods: </strong>We used genome-wide association data for symptoms of PMDs (S-PMD, <i>n</i> = 67 068) from the Norwegian Mother, Father and Child Cohort Study (MoBa), and for MPDs (schizophrenia, <i>n</i> = 130 644; bipolar disorder, <i>n</i> = 827 335; major depression, <i>n</i> = 1 918 432) from the Psychiatric Genomic Consortium. Shared genetic loci were identified with the conjunctional false discovery rate (conjFDR). Genes mapped to the identified loci were included in functional and pharmacological gene-set enrichment analyses (GSEAs).</p><p><strong>Results: </strong>We identified 20 loci shared between S-PMD and the MPDs, including 19 novel loci for S-PMD (conjFDR<0.05). GSEA revealed genes involved in calcium signaling and neuronal projection pathways. The drug enrichment analysis identified 36 drugs, including riluzole and mianserin, significantly associated with the identified molecular pathways.</p><p><strong>Conclusions: </strong>We identified 20 genetic loci shared between the S-PMD and MPDs, implicating calcium transmission in the pathogenesis of PMDs. Together with the drug enrichment results, this provides a biological basis for repurposing existing drugs in the treatment of PMD.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e99"},"PeriodicalIF":6.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Keeping the body in mind: Development of the Transdiagnostic Global Impression-Somatic Symptoms and Signs (TGI-3S) scale.","authors":"Roger S McIntyre, Agota Barabassy, Zsofia Borbala Dombi, György Németh, Thomas Brevig, Stefan Leucht, Allan H Young, Paolo Fusar-Poli, Katharina Domschke, Philip Gorwood, Philip D Havey, Christoph U Correll","doi":"10.1192/j.eurpsy.2026.12252","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12252","url":null,"abstract":"<p><strong>Background: </strong>It is well-established that mental illness is associated with excess and premature mortality. Consequently, the assessment of physical health should be routine in the evaluation of persons living with mental disorders. Herein, we introduce the development of a global instrument to assess physical health status in persons with mental disorders.</p><p><strong>Methods: </strong>Following the development of the Transdiagnostic Global Impression-Psychopathology (TGI-P) scale, a novel scale of physical health status, the Transdiagnostic Global Impression-Somatic Symptoms and Signs (TGI-3S), was created using similar principles. Scale development followed a multistage process involving (1) item generation using deductive methods, (2) two content validations by an expert panel, and (3) two iterative usability-testing rounds with patients and caregivers. These rounds therefore assessed understandability and ease of use for wording, visual format, and emotional/cognitive load of the instrument. The psychometric validation is underway.</p><p><strong>Results: </strong>The TGI-3S was developed as a front-end screening tool resulting in a broad somatic burden map, rather than a diagnostic instrument. Throughout the development process, experts, patients, and caregivers evaluated the TGI-3S positively. In the final usability round, 96% found the aim of the scale clear, and 87% considered the instructions easy to follow. The scale demonstrated high-level usability, with 72% completing the TGI-3S in <5 minutes. Emotional and cognitive burden of completing the TGI-3S was rated as low, and item wording was well-understood.</p><p><strong>Conclusions: </strong>With psychometric validation underway, the TGI-3S offers an anamnesis-embedded, brief, yet comprehensive tool for facilitating the assessment of somatic health in patients with mental disorders.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e97"},"PeriodicalIF":6.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal DNA methylation dynamics distinguish persistent and remitted attention-deficit/hyperactivity disorder in childhood and adolescence.","authors":"Jo Wrigglesworth, Valentine Chirokoff, Peter D Fransquet, Jeffrey M Craig, Tim J Silk","doi":"10.1192/j.eurpsy.2026.12255","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12255","url":null,"abstract":"<p><strong>Background: </strong>Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder, with symptoms that remit or persist over time. Biological mechanisms underlying symptom change remain poorly understood, though epigenetic processes, like DNA methylation (DNAm), may serve as dynamic biomarkers of clinical outcomes. We examined change in DNAm in children and adolescents with and without ADHD, including differences between remitted and persistent ADHD.</p><p><strong>Methods: </strong>We analyzed 219 saliva samples from 94 participants (aged 9.5-14.5 years) attending two to three waves of NICAP (Neuroimaging of the Children's Attention Project). DNAm was profiled using the Infinium MethylationEPIC BeadChip. Linear mixed models adjusted for age, sex, medication, batch, and cell-proportion assessed longitudinal change. Comparisons included (1) individuals with versus without ADHD, (2) persistent or remitted ADHD versus without ADHD, and (3) persistent versus remitted ADHD. False discovery rate correction controlled for multiple testing (FDR-adjusted-<i>p</i> < 0.05).</p><p><strong>Results: </strong>Comparison (1) showed null findings after correction for multiple testing. In contrast to those without ADHD (2), the average DNAm was statistically different at 2 sites in persistent ADHD (FDR-adjusted-<i>p</i> < 0.05) and 3 sites in remitted ADHD (FDR-adjusted-<i>p</i> < 0.03), and methylation of 3 additional CpGs differentially changed in persistent ADHD (FDR-adjusted-<i>p</i> < 0.04). Remitted differed from persistent ADHD (3) at 4 CpGs, including cg21443143 (<i>ZFAT</i>), which showed a decline over time. Gene enrichment links findings to brain structures and function, though these did not survive multiple testing.</p><p><strong>Conclusions: </strong>Our study identified several epigenetic differences between remitted and persistent ADHD outcomes from typical development, and from each other. Given the early stage of this research, our findings warrant further prospective epigenome-wide studies into these diagnostic trajectories.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e98"},"PeriodicalIF":6.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obsessional jealousy: Provisional research criteria and report of 34 cases.","authors":"David Mataix-Cols, Josef Isung, Anna Norberg, Sigrid Elfström, Johanna Linde, Johan Bjureberg, Long-Long Chen, Johan Åhlén","doi":"10.1192/j.eurpsy.2026.12263","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2026.12263","url":null,"abstract":"<p><strong>Background: </strong>Obsessional jealousy is described in DSM-5 under Other Specified Obsessive-Compulsive and Related Disorders, yet operationalized criteria and clinical characterization are lacking. This study aimed to develop and field-test provisional research criteria for obsessional jealousy and describe the clinical features of individuals meeting these criteria.</p><p><strong>Methods: </strong>Provisional research criteria were developed based on DSM-5 descriptions and applied in a self-referred sample of individuals reporting problematic jealousy (<i>n</i> = 58). Participants underwent structured clinical assessment, including best-estimate diagnostic procedures, evaluation of differential diagnoses, and measures of functional impairment. Participants' views on introducing a formal jealousy diagnosis were explored.</p><p><strong>Results: </strong>Among the participants, 34 (59%) met the provisional research criteria. The criteria showed strong sensitivity but modest specificity, reflecting a deliberately conservative threshold to avoid over-pathologization. All individuals meeting criteria were judged to meet DSM-5 and ICD-11 definitions of mental disorder. Obsessional jealousy was typically recurrent across relationships, with onset in mid-adolescence and clinical significance emerging in early adulthood. Participants showed generally good insight; comorbidity was common with mood and anxiety disorders. Many reported prior help-seeking and ongoing need for treatment. Participants expressed balanced views regarding formal diagnosis, citing both potential benefits and risks.</p><p><strong>Conclusions: </strong>These findings identify a group of individuals with pervasive, recurrent obsessional jealousy that is distressing, impairing, and not readily explained by existing diagnostic categories. The proposed criteria provide an initial framework for research and clinical development but require further refinement and validation in more representative community and clinical samples, with careful attention to diagnostic boundaries, transcultural aspects, and stakeholder perspectives.</p>","PeriodicalId":520621,"journal":{"name":"European psychiatry : the journal of the Association of European Psychiatrists","volume":"69 1","pages":"e102"},"PeriodicalIF":6.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}