European heart journal. Quality of care & clinical outcomes最新文献

{"title":"Prospective validation of the AUB-HAS2 cardiovascular risk index.","authors":"Habib A Dakik, Mahmoud Eldirani, Chris Kaspar, Omar Chehab, Ahmad Msheik, Maha Makki, Hani Tamim","doi":"10.1093/ehjqcco/qcaa077","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa077","url":null,"abstract":"","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"96-97"},"PeriodicalIF":5.2,"publicationDate":"2022-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38555979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national burden of ischaemic heart disease and its attributable risk factors, 1990-2017: results from the Global Burden of Disease Study 2017.","authors":"Haijiang Dai,&nbsp;Arsalan Abu Much,&nbsp;Elad Maor,&nbsp;Elad Asher,&nbsp;Arwa Younis,&nbsp;Yawen Xu,&nbsp;Yao Lu,&nbsp;Xinyao Liu,&nbsp;Jingxian Shu,&nbsp;Nicola Luigi Bragazzi","doi":"10.1093/ehjqcco/qcaa076","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa076","url":null,"abstract":"<p><strong>Aims: </strong>The aim of this study was to estimate the burden and risk factors for ischaemic heart disease (IHD) in 195 countries and territories from 1990 to 2017.</p><p><strong>Methods and results: </strong>Data from the Global Burden of Disease Study 2017 were used. Prevalence, incidence, deaths, years lived with disability (YLDs), and years of life lost (YLLs) were metrics used to measure IHD burden. Population attributable fraction was used to estimate the proportion of IHD deaths attributable to potentially modifiable risk factors. Globally, in 2017, 126.5 million [95% uncertainty interval (UI) 118.6 to 134.7] people lived with IHD and 10.6 million (95% UI 9.6 to 11.8) new IHD cases occurred, resulting in 8.9 million (95% UI 8.8 to 9.1) deaths, 5.3 million (95% UI 3.7 to 7.2) YLDs, and 165.0 million (95% UI 162.2 to 168.6) YLLs. Between 1990 and 2017, despite the decrease in age-standardized rates, the global numbers of these burden metrics of IHD have significantly increased. The burden of IHD in 2017 and its temporal trends from 1990 to 2017 varied widely by geographic location. Among all potentially modifiable risk factors, age-standardized IHD deaths worldwide were primarily attributable to dietary risks, high systolic blood pressure, high LDL cholesterol, high fasting plasma glucose, tobacco use, and high body mass index in 2017.</p><p><strong>Conclusion: </strong>Our results suggested that IHD remains a major public health challenge worldwide. More effective and targeted strategies aimed at implementing cost-effective interventions and addressing modifiable risk factors are urgently needed, particularly in geographies with high or increasing burden.</p>","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"50-60"},"PeriodicalIF":5.2,"publicationDate":"2022-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38555981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of autoimmune diseases with cardiomyopathy: a nationwide follow-up study from Sweden.","authors":"Xinjun Li,&nbsp;Jan Sundquist,&nbsp;Veronica Nymberg,&nbsp;Kristina Sundquist","doi":"10.1093/ehjqcco/qcab044","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcab044","url":null,"abstract":"<p><strong>Aims: </strong>Certain autoimmune diseases (ADs), such as Crohn's disease and celiac diseases, have been linked to acute cardiovascular disorders. We examined whether there is an association between 43 different ADs and risk of subsequent hospitalization and mortality of cardiomyopathy in a nationwide follow-up study in Sweden.</p><p><strong>Methods and results: </strong>All individuals in Sweden hospitalized with a main diagnosis of an AD (n = 955 410) without previous or coexisting cardiomyopathy, between 1 January 1987 and 31 December 2018, were followed for hospitalization or mortality of cardiomyopathy. The reference population was the total population of Sweden. Standardized incidence ratios (SIRs) for cardiomyopathy were calculated. Overall risk of cardiomyopathy during the first year after hospitalization for an AD was 3.63 [99% confidence interval (CI) 3.29-4.00]. A total of 21 of the 43 ADs studied were associated with an increased risk of cardiomyopathy during the first year after hospitalization. The overall risk of cardiomyopathy decreased over time, from 1.18 (99% CI 1.12-1.25) after 1+ year to 1.07 (99% CI 0.96-1.19) after 5+ years. Females generally had higher SIRs than males. The ADs for which the SIRs of cardiomyopathy were highest after 1 year of hospitalization included Crohn's disease (1.92), rheumatoid arthritis (1.57), sarcoidosis (1.48), and psoriasis (1.31).</p><p><strong>Conclusion: </strong>Most ADs are associated with an increased risk of cardiomyopathy, particularly in the first year after hospital admission. Our findings show that many hospitalized ADs are tightly linked to cardiomyopathy but the mechanisms need to be further evaluated.</p>","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"79-85"},"PeriodicalIF":5.2,"publicationDate":"2022-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39258183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of long-term mortality between patients living alone vs. patients living with others with acute coronary syndrome treated with percutaneous coronary intervention: reply.","authors":"Mitsuhiro Takeuchi,&nbsp;Manabu Ogita,&nbsp;Hideki Wada,&nbsp;Daigo Takahashi,&nbsp;Yui Nozaki,&nbsp;Ryota Nishio,&nbsp;Kentaro Yasuda,&nbsp;Norihito Takahashi,&nbsp;Taketo Sonoda,&nbsp;Shoichiro Yatsu,&nbsp;Jun Shitara,&nbsp;Shuta Tsuboi,&nbsp;Tomotaka Dohi,&nbsp;Satoru Suwa,&nbsp;Katsumi Miyauchi,&nbsp;Hiroyuki Daida","doi":"10.1093/ehjqcco/qcaa028","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa028","url":null,"abstract":"","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"340"},"PeriodicalIF":5.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37810188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of relative wall thickness of left ventricle with incidence of thromboembolism in patients with non-valvular atrial fibrillation: The Fushimi AF Registry.","authors":"Yuji Tezuka,&nbsp;Moritake Iguchi,&nbsp;Yasuhiro Hamatani,&nbsp;Hisashi Ogawa,&nbsp;Masahiro Esato,&nbsp;Hikari Tsuji,&nbsp;Hiromichi Wada,&nbsp;Koji Hasegawa,&nbsp;Mitsuru Abe,&nbsp;Gregory Y H Lip,&nbsp;Masaharu Akao","doi":"10.1093/ehjqcco/qcaa003","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa003","url":null,"abstract":"<p><strong>Aims: </strong>Atrial fibrillation (AF) increases the risk of thromboembolism, such as ischaemic stroke or systemic embolism (SE). The aim of this study was to investigate the relationship between left ventricular relative wall thickness (RWT) and the risk of thromboembolism in patients with non-valvular AF.</p><p><strong>Methods and results: </strong>The Fushimi AF Registry is a community-based prospective survey of the patients with AF in Japan. Analyses were performed on 3067 non-valvular AF patients, in which RWT values determined by transthoracic echocardiography were available at the baseline. The high-RWT group (RWT above the median) was more often female, older, and had higher systolic blood pressure, CHADS2 and CHA2DS2-VASc scores, as compared with low-RWT group. During the median follow-up period of 1309 days, there was a higher incidence of ischaemic stroke/SE in the high-RWT group [unadjusted hazard ratio (HR), 1.91; 95% confidence interval (CI), 1.42-2.59]. On multivariate Cox regression analysis, including the components of CHA2DS2-VASc score, left atrial diameter, oral anticoagulant prescription at baseline, and type of AF, high RWT was independently associated with ischaemic stroke/SE (adjusted HR, 1.81; 95% CI, 1.34-2.47). Stratified analysis demonstrated no significant interaction for any subgroups. In Kaplan-Meier analysis, ordinal RWT quartiles stratified the incidence of ischaemic stroke/SE. Finally, addition of RWT to CHA2DS2-VASc score increased the performance of risk stratification for the incidence of stroke/SE.</p><p><strong>Conclusion: </strong>Relative wall thickness was independently associated with ischaemic stroke/SE among Japanese patients with non-valvular AF, suggesting the importance of left ventricular morphology in contributing to adverse outcomes, particularly thromboembolism.</p>","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"273-283"},"PeriodicalIF":5.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37575461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statin dose titration patterns and subsequent major cardiovascular events in very high-risk patients: estimates from Swedish population-based registry data.","authors":"Jonas Banefelt,&nbsp;Maria Lindh,&nbsp;Maria K Svensson,&nbsp;Björn Eliasson,&nbsp;Ming-Hui Tai","doi":"10.1093/ehjqcco/qcaa023","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa023","url":null,"abstract":"<p><strong>Aims: </strong>Clinical studies have demonstrated the efficacy of intensive statin therapy in lowering low-density lipoprotein cholesterol and cardiovascular (CV) events. Our objective was to examine statin titration patterns and the association between titration patterns and subsequent CV events in very high-risk patients.</p><p><strong>Methods and results: </strong>Using Swedish national population-based registry data, we identified 192 435 patients with very high risk of atherosclerotic CV disease initiated on moderate-intensity statin therapy between 2006 and 2013. Outcomes of interest were titration to high-intensity therapy and the major adverse cardiovascular events (MACE) composite (myocardial infarction, ischaemic stroke, and CV death) outcome. Cumulative incidence of MACE was assessed by titration status 1-year post-treatment initiation in patients adherent to treatment during the first year, using a 12-week cut-off from initiation to define early, delayed and no up-titration to high-intensity statins. Cox regression analysis was used to estimate adjusted hazard ratios (HRs). In 144 498 eligible patients, early titration was associated with significantly lower risk of MACE in the subsequent 2 years compared to no up-titration (HR 0.76, P < 0.01]. Delayed up-titration was associated with a smaller reduction (HR 0.88, P = 0.08). The majority of patients did not up-titrate.</p><p><strong>Conclusion: </strong>Early up-titration to high-intensity statins was independently associated with lower risk of subsequent CV events compared to no up-titration. Delayed up-titration was not associated with the same benefit. Despite the higher risk associated with no up-titration, few patients at very high CV risk who started treatment on moderate-intensity up-titrated to high intensity, indicating a potential need for more aggressive lipid management of these patients in clinical practice.</p>","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"323-331"},"PeriodicalIF":5.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37794136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shared decision-making: the patient on the forefront of care coordination.","authors":"Jeroen M Hendriks,&nbsp;Geraldine Lee","doi":"10.1093/ehjqcco/qcaa039","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa039","url":null,"abstract":"","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"231-233"},"PeriodicalIF":5.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38090587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is complete revascularization for multivessel disease during primary percutaneous coronary intervention associated with lower cardiovascular mortality? An updated meta-analysis and trial sequential of randomized trials.","authors":"Islam Y Elgendy,&nbsp;Mohamed Gad,&nbsp;Ayman Elbadawi,&nbsp;Akram Y Elgendy,&nbsp;Ahmed N Mahmoud","doi":"10.1093/ehjqcco/qcz067","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcz067","url":null,"abstract":"","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"341-342"},"PeriodicalIF":5.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcz067","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37575541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"English proficiency and clinical outcomes in primary percutaneous coronary intervention.","authors":"Moghees Hanif,&nbsp;Mazhar Choudhry,&nbsp;Qasid Bhatti,&nbsp;Ehsan Nawaz,&nbsp;Mahmood Ahmad","doi":"10.1093/ehjqcco/qcaa010","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa010","url":null,"abstract":"","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"338"},"PeriodicalIF":5.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37614258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gaps in patient-reported outcome measures in randomized clinical trials of cardiac catheter ablation: a systematic review.","authors":"Yang Chen,&nbsp;Myura Nagendran,&nbsp;Manuel Gomes,&nbsp;Peter V Wharton,&nbsp;Rosalind Raine,&nbsp;Pier D Lambiase","doi":"10.1093/ehjqcco/qcaa022","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcaa022","url":null,"abstract":"<p><p>The aim of this systematic review was to evaluate randomized clinical trials (RCTs) of cardiac catheter ablation (CCA) and to assess the prevalence, characteristics and reporting standards of clinically relevant patient-reported outcome measures (PROMs). Electronic database searches of Medline, Embase, CENTRAL, and the WHO Trial Registry were conducted in March 2019. The study protocol was registered on PROSPERO (CRD42019133086). Of 7125 records identified, 237 RCTs were included for analysis, representing 35 427 patients with a mean age of 59 years. Only 43 RCTs (18%) reported PROMs of which 27 included a generic PROM that measured health-related quality of life (HRQL) necessary to conduct comparative effectiveness research. There was notable under-representation of certain patient groups-only 31% were women and only 8% were of non-Caucasian ethnicity, in trials which reported such data. The reporting standard of PROMs was highly variable with 8-62% adherence against CONSORT PRO-specific items. In summary, PROMs play a crucial role in determining the clinical and cost-effectiveness of treatments which primarily offer symptomatic improvement, such as CCA. Their underuse significantly limits evaluation of the comparative effectiveness of treatments. Using CCA as an exemplar, there are additional issues of infrequent assessment, poor reporting and under-representation of many population groups. Greater use of PROMs, and specifically validated HRQL questionnaires, is paramount in giving patients a voice in studies, generating more meaningful comparisons between treatments and driving better patient-centred clinical and policy-level decision-making.</p>","PeriodicalId":520616,"journal":{"name":"European heart journal. Quality of care & clinical outcomes","volume":" ","pages":"234-242"},"PeriodicalIF":5.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/ehjqcco/qcaa022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37736309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}