Diabetic medicine : a journal of the British Diabetic Association最新文献

{"title":"Publication bias and confirmation bias in health-economic studies in diabetes-related foot disease?","authors":"Jaap J van Netten, Marcel G W Dijkgraaf, Sicco A Bus","doi":"10.1111/dme.70425","DOIUrl":"https://doi.org/10.1111/dme.70425","url":null,"abstract":"","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70425"},"PeriodicalIF":3.4,"publicationDate":"2026-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"User satisfaction with fingerstick versus continuous glucose monitoring in surgical wards: A two-centre non-randomised clinical trial.","authors":"Tine Lumbye Thomsen, Marian Christin Petersen, Line Abrahamsen, Torill Donslund Nielsen, Karoline Schousboe, Sören Möller, Helen Schultz","doi":"10.1111/dme.70422","DOIUrl":"https://doi.org/10.1111/dme.70422","url":null,"abstract":"<p><strong>Aims: </strong>To compare person-reported outcomes on point-of-care (POC) fingerstick glucose monitoring (FSGM) with POC continuous glucose monitoring systems (CGMS) in adults admitted to surgical wards. The primary outcome was convenience; the secondary outcome was satisfaction with diabetes-related treatment.</p><p><strong>Methods: </strong>This two-centre non-randomised clinical trial consisted of an initial standard care period with FSGM, followed by a period with POC CGMS. The trial included adults at risk of hypo- or hyperglycaemia in Danish surgical wards who were initially prescribed glucose monitoring at least four times daily and expected to be hospitalised for a minimum of three days. Person-reported outcomes were assessed at discharge using the validated Danish Diabetes Treatment Satisfaction Questionnaire for Inpatients (DTSQ-IP).</p><p><strong>Results: </strong>A total of 199 adults were included. Adjusted analyses showed significantly higher convenience (p < 0.0001) and overall satisfaction (p = 0.001) with POC CGMS than with FSGM. CGMS also produced significantly higher adjusted scores for flexibility, willingness to recommend and continue the treatment, quality of communication with staff, time spent with diabetes nurses and the discharge treatment plan. No between-group differences were found in experiences of hypoglycaemia, hyperglycaemia and glucose monitoring or satisfaction with understanding of the treatment, staff knowledge of participants' treatment or responsiveness to needs.</p><p><strong>Conclusions: </strong>Among adults at risk of hypo- or hyperglycaemia in surgical wards, CGMS as POC provided greater convenience and satisfaction than FSGM regardless of diabetes status, reflecting greater comfort with CGMS. No differences were found in user-reported dysglycaemia.</p>","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70422"},"PeriodicalIF":3.4,"publicationDate":"2026-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Interpreting the cost-effectiveness of diabetes remission programmes beyond the durability of remission.","authors":"Mike Lean, Andrew Davies","doi":"10.1111/dme.70410","DOIUrl":"https://doi.org/10.1111/dme.70410","url":null,"abstract":"","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70410"},"PeriodicalIF":3.4,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interpreting the cost-effectiveness of diabetes remission programmes beyond the durability of remission.","authors":"Stjepan Škudar","doi":"10.1111/dme.70393","DOIUrl":"https://doi.org/10.1111/dme.70393","url":null,"abstract":"","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70393"},"PeriodicalIF":3.4,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of recommended footwear fit upon in-shoe pressures in feet with diabetes-An exploratory study.","authors":"Petra J Jones, Bijan Najafi, Melanie J Davies, Priscilla Sarkar, Adrian Palfreeman, Jo Luke, Rachel Berrington, Kamlesh Khunti, Katerina Tziannou, Carina Price","doi":"10.1111/dme.70418","DOIUrl":"https://doi.org/10.1111/dme.70418","url":null,"abstract":"<p><strong>Aims: </strong>Diabetes-related foot ulceration (DFU) can be caused by incorrectly fitting footwear, yet there is a lack of consensus around recommended toe gaps within footwear. We assessed mean in-shoe peak plantar pressures associated with alternative toe gap ranges during walking within standardised footwear at a standard pace. Secondary aims included assessing footwear fit and in-shoe pressures in habitual footwear.</p><p><strong>Methods: </strong>People with diabetes wore standardised footwear with three toe gap ranges: 0.5-1.0 cm, 1.0-1.5 cm and 1.5-2.0 cm. In-shoe peak plantar pressures were measured during walking at 1 m/s ± 5%. Twenty-five participants were recruited, with data available for 17 participants given footwear tolerance and equipment issues.</p><p><strong>Results: </strong>Mean right hallux in-shoe peak plantar pressures were higher in 1.5-2.0 cm toe gaps (236.3 ± 23.5 kilopascals) than in 0.5-1.0 cm toe gaps (142.2 ± 20.5 kPa, p = 0.03) based on linear regression single covariate analysis. More three-quarters of participants wore habitual footwear of incorrect length and almost half wore incorrect width.</p><p><strong>Conclusions: </strong>This exploratory study suggests that larger toe gaps may be associated with increased hallux plantar pressures, in some cases exceeding 200 kPa-a commonly cited threshold associated with increased DFU risk. These findings should be confirmed in larger, adequately powered studies.</p>","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70418"},"PeriodicalIF":3.4,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finger-stick glucose testing as an institutional stressor: Staff perspectives from long-term care.","authors":"Steven Trawley, Suzanne Kapp, Jieli Li, Alan Sinclair, Katharina Mattishent, Patrick Olivier, Grace Garces, Sybil A McAuley, Khadija Dossa, Rameez Hassan, Anna R Kahkoska","doi":"10.1111/dme.70416","DOIUrl":"https://doi.org/10.1111/dme.70416","url":null,"abstract":"","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70416"},"PeriodicalIF":3.4,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148382474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disentangling the effect of brain insulin resistance on brain health (BIR-BrainHealth): Rationale and study protocol.","authors":"Sabrina Wangler, Peter Sørensen, Konni Kass, Nicole Jaqueline Jensen, Mark Bitsch Vestergaard, Julia Hummel, Ronja Völk, Julie Christine Antvorskov, Flemming Pociot, Jørgen Rungby, Martin Heni, Henrik Bo Wiberg Larsson","doi":"10.1111/dme.70415","DOIUrl":"https://doi.org/10.1111/dme.70415","url":null,"abstract":"<p><strong>Aims: </strong>Insulin signalling in the brain is crucial for systemic metabolic regulation and cognitive function. In some individuals, these effects are reduced, a phenomenon referred to as brain insulin resistance (BIR). This condition may contribute to the elevated risk of cognitive decline and dementia in diabetes, yet its prevalence, mechanisms, and clinical relevance remain poorly understood. The BIR-BrainHealth study aims to (i) quantify BIR in adults with type 1 diabetes, type 2 diabetes, and without diabetes; (ii) assess its associations with cerebrovascular function and cognitive performance; and (iii) identify biomarkers that reflect BIR.</p><p><strong>Methods: </strong>BIR-BrainHealth is a multicentre prospective cohort study with baseline cross-sectional analyses conducted in Denmark and Germany. We plan to recruit a total of 150 adults (≈50 per group) who will undergo detailed metabolic and cognitive phenotyping, multimodal neuroimaging, and extensive biomarker profiling. Brain insulin response is assessed by cerebral blood flow changes to intranasal insulin administration measured by perfusion-weighted MRI. Additional MRI scans will be used for assessments of cerebrovascular reactivity, neurovascular coupling, blood-brain barrier integrity, and hypothalamic responses during an oral glucose tolerance test. Blood, urine, and faecal samples are collected in a biobank.</p><p><strong>Conclusions: </strong>BIR-BrainHealth will provide insight into how diabetes affects brain insulin signalling and cerebrovascular health, and how these alterations relate to cognitive performance. These findings will establish a robust foundation for future mechanistic and translational research, with the potential to advance strategies for monitoring and preventing cognitive decline.</p><p><strong>Trial registration: </strong>ISRCTN: ISRCTN15687967 and ClinicalTrials.gov: NCT07374705.</p>","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70415"},"PeriodicalIF":3.4,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148379487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute pancreatitis following sleeve gastrectomy with transit bipartition: A case report.","authors":"Yanqing Jiang, Xiaotian Pang, Zhongyang Zhang, Sijun Xie, Hao Yang, Ming He, Yuan Zhang","doi":"10.1111/dme.70326","DOIUrl":"10.1111/dme.70326","url":null,"abstract":"<p><strong>Introduction: </strong>Sleeve gastrectomy with transit bipartition (SG-TB) is an emerging metabolic and bariatric surgery (MBS) procedure for obesity and type 2 diabetes. Acute pancreatitis (AP) is a rare complication of other metabolic and bariatric surgery (MBS) procedures (incidence: 0.27%-3.6%), including Roux-en-Y Gastric Bypass (RYGB) and occurs after other MBS procedures such as Roux-en-Y Gastric Bypass (RYGB) and standard Laparoscopic Sleeve Gastrectomy (LSG), while no AP cases following SG-TB have been reported to date.</p><p><strong>Case presentation: </strong>We describe a 41-year-old female patient with obesity and type 2 diabetes (BMI 30.6 kg/m²) who developed AP on the 3rd day after an uncomplicated laparoscopic SG-TB. She presented with epigastric pain radiating to the back, mild elevation of serum amylase and lipase and magnetic resonance imaging findings consistent with the diagnosis of mild AP according to the 2012 Revised Atlanta Criteria.</p><p><strong>Discussion: </strong>The patient had moderately elevated preoperative triglycerides (5.0 mmol/L), which was below the classical threshold of 11.3 mmol/L for hypertriglyceridemia-induced AP, thus serving as a background risk factor for the onset, with no other definite etiological factors. Conservative treatment resolved symptoms, pancreatic enzyme levels normalized on the 7th postoperative day, and she was discharged uneventfully.</p><p><strong>Conclusion: </strong>This case highlights that AP should be included in the differential diagnosis of patients with abdominal pain in the early postoperative period after SG-TB. Biliogastric reflux-induced pancreatic duct hypertension following gastrojejunal anastomosis in SG-TB and iatrogenic mechanical/thermal injury may be the main pathogenic mechanisms, with the patient's metabolic status acting as a synergistic factor for early-onset AP.</p>","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70326"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147731197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What barriers need to be removed to incorporate resistance exercise into the lives of older adults with long-term diabetes and prefrailty? A deductive framework analysis using the Capability, Opportunity, Motivation and Behaviour (COM-B) behavioural science model.","authors":"Rachel Stocker, Siân Russell, Guy S Taylor, Miles D Witham, James A M Shaw, Daniel J West","doi":"10.1111/dme.70367","DOIUrl":"10.1111/dme.70367","url":null,"abstract":"<p><strong>Aims: </strong>Maintaining physical function, and thus independence, is essential for people ageing with diabetes. For older adults with long-term insulin-treated diabetes, managing frailty, preserving body mass index (BMI) and muscle strength and mitigating hypoglycaemia risk are key challenges. Resistance training (RT) offers benefits, including reduced hypoglycaemia risk, increased bone density and improved muscle strength, yet its uptake remains low. This study explores behavioural influences and barriers to RT participation among older adults living with insulin-treated diabetes and prefrailty.</p><p><strong>Methods: </strong>A qualitative approach was employed, involving semi-structured interviews with individuals living with prefrailty aged 60 years or older with insulin-treated diabetes (type 1 diabetes (n = 12); type 2 diabetes with BMI < =30 kg/m2 (n = 4)). Frailty was assessed using the Rockwood Clinical Frailty Scale (3-4). Data were analysed using framework analysis and aligned to the COM-B model of behaviour change to deductively identify barriers and facilitators.</p><p><strong>Results: </strong>Barriers to RT were identified across psychological capability, physical capability and social opportunity COM-B domains. Key barriers included fears of fatigue, hypoglycaemia and injury, diabetes-related complications and difficulties using RT equipment. Outdated advice about exercise safety and lack of awareness of RT's benefits further hindered participation. Facilitators included tailored education on diabetes-specific RT benefits, a supportive, flexible training environment and the presence of an exercise-competent partner.</p><p><strong>Conclusions: </strong>This study highlights perceptual and practical barriers that discourage older adults with diabetes and prefrailty from engaging in resistance exercise. Addressing these barriers through educational initiatives and creating adaptable exercise programmes could enhance exercise participation rates in this population.</p>","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70367"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13257896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147950656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between pre-incarceration related social determinants and glycaemic control in African Americans with criminal legal involvement and type 2 diabetes.","authors":"Olaitan Akinboboye, Rebekah J Walker, Jennifer A Campbell, Laura Hawks, Joni S Williams, Leonard E Egede","doi":"10.1111/dme.70342","DOIUrl":"10.1111/dme.70342","url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the relationship between pre-incarceration social determinants, demographic and clinical factors, and glycaemic control in African Americans with a history of criminal legal involvement and type 2 diabetes mellitus.</p><p><strong>Methods: </strong>One hundred and seventy-one adults were recruited from medical records and community centres in the Midwestern United States. The model was estimated using stepwise regression with forward selection to evaluate the relationship between pre-incarceration factors, demographic factors, clinical factors and glycaemic control among African Americans with a history of criminal legal involvement and type 2 diabetes.</p><p><strong>Results: </strong>The fully adjusted model showed that age, comorbidity count and medication were significantly associated with glycaemic control. Compared to using only oral hypoglycaemic agents, the combination of pills/oral hypoglycaemic agents and insulin (β: 1.30; 95% CI: 0.60, 1.99) and using insulin or injectables alone (β: 0.87; 95% CI: 0.07, 1.67) were associated with an increase in HbA1c. Additionally, each additional comorbidity (β: -0.22; 95% CI: -0.37, -0.08) was associated with a 0.22% decrease in HbA1c, and each unit increase in age (β: -0.05; 95% CI: -0.09, -0.01) was associated with a 0.05% decrease in HbA1c.</p><p><strong>Conclusion: </strong>Pre-incarceration factors were not associated with glycaemic control in African Americans with a history of criminal legal involvement and type 2 diabetes. Interventions that account for factors such as comorbidity, age and medication are essential for future research.</p>","PeriodicalId":520603,"journal":{"name":"Diabetic medicine : a journal of the British Diabetic Association","volume":" ","pages":"e70342"},"PeriodicalIF":3.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13622360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}