Clinical and experimental reproductive medicine最新文献

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A comparison of different O-antigen serogroups of Escherichia coli in semen samples of fertile and infertile men. 可育和不育男性精液样品中大肠杆菌不同o抗原血清群的比较。

IF 1.8

Clinical and experimental reproductive medicine Pub Date : 2022-03-01 Epub Date: 2021-11-04 DOI: 10.5653/cerm.2020.04161

Ali Nabi, Mohammad Bagher Khalili, Gilda Eslami, Mahmood Vakili, Fatemeh Anbari, Alireza Torki

{"title":"A comparison of different O-antigen serogroups of Escherichia coli in semen samples of fertile and infertile men.","authors":"Ali Nabi, Mohammad Bagher Khalili, Gilda Eslami, Mahmood Vakili, Fatemeh Anbari, Alireza Torki","doi":"10.5653/cerm.2020.04161","DOIUrl":"https://doi.org/10.5653/cerm.2020.04161","url":null,"abstract":"Objective: Male genital tract infections have been associated with infertility, and Escherichia coli has drawn increasing attention as an important bacterium in this context. This investigation aimed to characterize and compare the distributions of O-antigen serogroups of E. coli in the semen samples of fertile and infertile men.Methods: In this case-control study, semen samples were collected from 618 fertile and 1,535 infertile men. The E. coli-positive samples were evaluated in terms of concentration, morphology, viability, and motility parameters according to the World Health Organization 2010 guidelines. Finally, different serogroups of E. coli were identified by multiplex polymerase chain reaction targeting the O-antigen variations of the bacterium.Results: The prevalence of E. coli among fertile men was significantly higher than among infertile men (p<0.001). The sperm morphology, viability, and motility in the E. coli-positive fertile group were significantly higher than in the E. coli-positive infertile group (p<0.001). E. coli O6 was the most prevalent serogroup found in both groups. However, there was no significant difference in the frequency of different serogroups of E. coil between the two groups (p=0.55).Conclusion: Despite the higher prevalence of E. coli among fertile men, E. coli had more detrimental effects on semen parameters in infertile men. There was no significant difference in E. coli serogroups between the fertile and infertile groups.","PeriodicalId":520591,"journal":{"name":"Clinical and experimental reproductive medicine","volume":" ","pages":"33-39"},"PeriodicalIF":1.8,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/62/eb/cerm-2020-04161.PMC8923631.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39626064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Azoospermic men with isolated elevation of folliclestimulating hormone represent a specific subpopulation of patients with poor reproductive outcomes. 孤立性促卵泡激素升高的无精子男性代表了生殖结果较差的患者的一个特定亚群。

IF 1.8

Clinical and experimental reproductive medicine Pub Date : 2022-03-01 Epub Date: 2022-01-28 DOI: 10.5653/cerm.2021.04623

Safar Gamidov, Taras Shatylko, Alina Popova, Natig Gasanov, Gennadiy Sukhikh

{"title":"Azoospermic men with isolated elevation of folliclestimulating hormone represent a specific subpopulation of patients with poor reproductive outcomes.","authors":"Safar Gamidov, Taras Shatylko, Alina Popova, Natig Gasanov, Gennadiy Sukhikh","doi":"10.5653/cerm.2021.04623","DOIUrl":"https://doi.org/10.5653/cerm.2021.04623","url":null,"abstract":"Objective: This study aimed to describe a distinct subpopulation of azoospermic patients with isolated elevation of follicle-stimulating hormone (iFSH) and poor outcomes of microdissection testicular sperm extraction (microTESE).Methods: A retrospective analysis of microTESE outcomes was conducted among 565 patients with non-obstructive azoospermia (NOA). Testicular pathology was assessed by the dominant histological pattern and Bergmann-Kliesch score (BKS). Descriptive statistics were presented for the iFSH subgroup. Inhibin B levels, the sperm retrieval rate (SRR), and BKS were compared in iFSH patients and other NOA patients.Results: The overall SRR was 33.3% per microTESE attempt. The median BKS was 0.6 (interquartile range, 0-2). Of all NOA patients, 132 had iFSH, and microTESE was successful only in 11 of those cases, with an SRR of 8.3%, while the total SRR in other NOA patients was 38.1% (p<0.001). iFSH had a sensitivity of 32.1% (95% confidence interval [CI], 27.4%-36.8%) and specificity of 94.1% (95% CI, 90.8-97.5%) as a predictor of negative microTESE outcomes.Conclusion: Patients with iFSH may harbor a distinct testicular phenotype with total loss of the germ cell population and poor outcomes of surgical sperm retrieval.","PeriodicalId":520591,"journal":{"name":"Clinical and experimental reproductive medicine","volume":" ","pages":"62-69"},"PeriodicalIF":1.8,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f4/47/cerm-2021-04623.PMC8923626.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39626063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A spontaneous pregnancy and live birth in a woman with primary infertility following the excision of an ovarian adrenal rest tumor: A rare case. 卵巢肾上腺素瘤切除后原发不孕症患者的自然妊娠和活产:罕见病例。

IF 1.8

Clinical and experimental reproductive medicine Pub Date : 2020-12-01 Epub Date: 2020-10-23 DOI: 10.5653/cerm.2020.03692

Hacer Uyanıkoglu, Gonul Ozer, Semra Kahraman

引用次数: 3