Vera Vaz Ferreira, Inês Ângelo, Boban Thomas, Arjun K Ghosh
{"title":"Cardiovascular complications of treatment for prostate cancer.","authors":"Vera Vaz Ferreira, Inês Ângelo, Boban Thomas, Arjun K Ghosh","doi":"10.12968/hmed.2022.0334","DOIUrl":"https://doi.org/10.12968/hmed.2022.0334","url":null,"abstract":"<p><p>Prostate cancer, an androgen-dependent disease, is one of the leading causes of mortality in men. It can present as localised disease, locally advanced or distant metastatic disease. Treatment options for patients with prostate cancer include surgery, chemotherapy, brachytherapy, radiation therapy and hormonal therapy. There are multiple treatment options for each stage of the disease, but hormone therapy is usually reserved for advanced stages. Cardiovascular disease is the leading cause of death in patients with prostate cancer and both diseases share common risk factors. Hormone therapy improves prognosis in patients with more advanced disease, albeit at the cost of cardiovascular toxicity. Hormone therapy can be achieved with the use of agonists and antagonists of gonadotropin-releasing hormone receptors, androgen receptor blockers and enzyme inhibitors of androgen synthesis. Drug-specific cardiotoxicity caused by treatments for prostate cancer has not been fully elucidated. Cardiovascular disease in patients with prostate cancer is mainly managed via an ABCDE approach, a strategy to optimise common risk factors. With newer agents improving the prognosis for patients with prostate cancer, cardiovascular toxicity will have a greater impact on the outcomes of these patients. This article reviews cardiovascular risks associated with therapy for prostate cancer with a focus on hormonal therapy.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-12"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40457412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The cervical spine in paediatric radiology.","authors":"Sparsh Prasher, Caren Landes","doi":"10.12968/hmed.2022.0076","DOIUrl":"https://doi.org/10.12968/hmed.2022.0076","url":null,"abstract":"<p><p>Accurate radiological assessment of the cervical spine is vital in the management of the child presenting with trauma. Compared to an adult's spine, the significant differences in the developmental anatomy (variants or synchondrosis), biomechanics and fracture patterns in the paediatric cervical spine makes assessment difficult, even for experienced radiologists. This review discusses the unique biomechanical factors, developmental anatomy, patterns of injury and imaging strategy in the paediatric population.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-9"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40548112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are opioids safe for use in obstetric general anaesthesia?","authors":"Michelle Bone, Toby Hoskins","doi":"10.12968/hmed.2022.0307","DOIUrl":"https://doi.org/10.12968/hmed.2022.0307","url":null,"abstract":"<p><p>The use of opioids during caesarean section has historically been avoided because of concerns regarding neonatal compromise. There is now more evidence regarding the safety and benefits of opioids in obstetric general anaesthesia, so should opioids be used during induction of anaesthesia for caesarean section?</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-2"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40456964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effects of shame and stigma on patient care.","authors":"Luna Dolezal","doi":"10.12968/hmed.2022.0441","DOIUrl":"https://doi.org/10.12968/hmed.2022.0441","url":null,"abstract":"<p><p>Stigma in healthcare has been associated with a range of negative outcomes, such as delays in seeking treatment, avoiding clinical encounters and mental distress. This editorial discusses the experience of stigma and argues that understanding shame anxiety and adopting 'shame-sensitive' practice is beneficial in healthcare.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-3"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40556968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fear of using medicines in pregnancy risks the lives of women and children.","authors":"Christine Ekechi","doi":"10.12968/hmed.2022.0312","DOIUrl":"https://doi.org/10.12968/hmed.2022.0312","url":null,"abstract":"<p><p>Medicine research and development has been instrumental in improving outcomes for countless individuals, but women, especially pregnant women, have been left behind. Disadvantaged during pregnancy as a result of apprehension over drug use for new or existing conditions, women face worse outcomes for under- or untreated disease. Solving this problem will require input from regulators, the pharmaceutical industry and clinicians.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-3"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40569492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles C Southey, Jonathan Birns, Peter Sommerville, Ajay Bhalla
{"title":"Transient unilateral weakness: is it a transient ischaemic attack?","authors":"Charles C Southey, Jonathan Birns, Peter Sommerville, Ajay Bhalla","doi":"10.12968/hmed.2022.0414","DOIUrl":"https://doi.org/10.12968/hmed.2022.0414","url":null,"abstract":"<p><p>Transient ischaemic attack is an emergency medical condition that causes brief negative focal neurological symptoms such as unilateral weakness. The symptoms herald a high risk of stroke and hence require urgent assessment. The challenge lies in the brevity and compendium of associated symptoms that can 'mimic' a plethora of other conditions. The result is a high rate of referrals to transient ischaemic attack clinics for these stroke mimics. This article highlights the diagnostic challenges in transient ischaemic attack with relevance to unilateral weakness.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-7"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40547642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harman Khatkar, Jonathon Kyriakides, John McNamara
{"title":"The environmental impact of orthopaedic surgery: assessing strategies for change.","authors":"Harman Khatkar, Jonathon Kyriakides, John McNamara","doi":"10.12968/hmed.2022.0388","DOIUrl":"https://doi.org/10.12968/hmed.2022.0388","url":null,"abstract":"<p><p>Climate change poses one of the most critical threats to humanity. Surgical care needs to be considered in relation to the impending climate emergency. Little thought appears to have been given to the role of operating departments as a high-yield target for environmental change. This article evaluates the environmental impact of orthopaedic surgery, focusing on anaesthesia, waste management and surgical hardware. Developing 'green' operating protocols should be the minimum expectation of orthopaedic departments. Just as the management of complex surgical pathology requires a multidisciplinary approach, mitigating the environmental impact of surgical endeavour requires collective action and buy-in.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-4"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40556956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel P Williams, Jia L Stevens, Yohinee K Rajendran
{"title":"Sodium-glucose co-transporter-2 inhibitors and the risk of perioperative euglycaemic diabetic ketoacidosis.","authors":"Samuel P Williams, Jia L Stevens, Yohinee K Rajendran","doi":"10.12968/hmed.2022.0398","DOIUrl":"https://doi.org/10.12968/hmed.2022.0398","url":null,"abstract":"<p><p>Sodium-glucose co-transporter-2 inhibitors are increasingly prescribed for patients with type 2 diabetes. Their use has been associated with life-threatening diabetic ketoacidosis. The risk is increased during times of fasting and intercurrent medical illness, which are common in the perioperative period. Diagnosis can be difficult, so perioperative clinicians must be familiar with preventing and recognising such complications.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-2"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40556485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bullying in trauma and orthopaedics: a survey of staff in orthopaedic departments in the UK.","authors":"Arin Mahmoud, Kanatheepan Shanmuganathan, Charmilie Chandrakumar, Batya Stimler, Luckshmana Jeyaseelan","doi":"10.12968/hmed.2022.0390","DOIUrl":"https://doi.org/10.12968/hmed.2022.0390","url":null,"abstract":"<p><strong>Background/aims: </strong>An orthopaedic department requires good teamwork and communication to function. This is undermined by bullying and harassment, which may affect the victim's health and career.</p><p><strong>Methods: </strong>A 26-item questionnaire was sent to all delegates who registered for a free orthopaedic webinar teaching series via email and social media. This study includes the responses from all those who had worked in a UK orthopaedic department.</p><p><strong>Results: </strong>There were 168 respondents from varying backgrounds; 17.9% had experienced bullying or harassment in their orthopaedic department, while 36.3% had witnessed it. Women and people from ethnic minority backgrounds suffered 10.2% and 6.9% higher rates of bullying than their male or white counterparts respectively.</p><p><strong>Conclusions: </strong>The results demonstrate that despite attempts to reduce bullying in orthopaedics, it remains prevalent, and particularly affects women and those from ethnic minority backgrounds. Orthopaedic departments must adapt to reflect changes in society.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-10"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40456025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tips for the shop floor for trainees working in paediatric hospital medicine.","authors":"Anita Chithiramohan, Andrew Taylor","doi":"10.12968/hmed.2021.0477","DOIUrl":"https://doi.org/10.12968/hmed.2021.0477","url":null,"abstract":"<p><p>Paediatrics is one of the most useful rotations for junior doctors to undertake, allowing them to learn and develop the skills necessary to provide child-centred care. As with any speciality, it can be daunting to cover on-calls with no previous experience, so guidance for those starting paediatric placements can be valuable. This article provides up-to-date information and preparation strategies for all junior doctors, whether they are considering undertaking a paediatric rotation as a trainee or in a trust post, or are already in training, such as on general practitioner vocational schemes.</p>","PeriodicalId":520576,"journal":{"name":"British journal of hospital medicine (London, England : 2005)","volume":" ","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40546029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}