The Canadian journal of urology最新文献

{"title":"Same-day surgical cancellations in pediatric urology: identifying trends for quality improvement.","authors":"Tyler Overholt Daniel, David Thole, Randy Casals, Anthony Atala, Steve Hodges, Marc Colaco","doi":"10.32604/cju.2026.074059","DOIUrl":"10.32604/cju.2026.074059","url":null,"abstract":"<p><strong>Objectives: </strong>Day of surgery cancellations present several workflow challenges that result in delay of care for patients and revenue loss for physicians. This study aimed to further understand same-day pediatric urology surgical cancellations, and the authors assessed identifiable trends for quality improvement over a one-year time period.</p><p><strong>Methods: </strong>Same-day surgical cancellations were prospectively identified at a single tertiary care center, Atrium Health Wake Forest Baptist, from 01 October 2022 to 30 September 2023. Reasons for cancellation were recorded per the parent/legal guardian and categorized as an avoidable or unavoidable cause. Demographic data, surgical rescheduling, and lost operating room time were also recorded. Descriptive and bivariate analyses were performed as indicated.</p><p><strong>Results: </strong>Of 2351 scheduled cases, 51 (2.2%) were cancelled the day of surgery. The most common cancellation type was a complete no-show with no reason provided from the family (39.2%). Of those with reported reasons, 54.8% were cancelled for avoidable causes. Of those cancelled, 66.7% were for patients of a minority race, with 11.8% of families indicating a need for translation services during visits. There was no difference in terms of race/ethnicity, distance lived from the hospital, or surgical type when comparing cancellation reason (p > 0.05). Only 51.0% of cases were rescheduled with a median delay of 38 days. A total of 59.3 h of operating room time was lost due to these cancellations.</p><p><strong>Conclusions: </strong>Same-day cancellations were identified in 2.2% of planned pediatric urology cases over a one-year period, with the majority of patients cancelled for avoidable reasons. Of cancelled cases, only 51.0% were rescheduled by the family, with a median delay of over one month. Additionally, 2/3rd of patients identified as a minority race, with 11.8% requiring translation services. This represents a vulnerable population who may require additional counseling for optimal patient and provider outcomes.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"693-698"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early clinical experience and learning curve of transperineal prostate biopsy with a novel angle-adjustable needle guide.","authors":"Erdem Öztürk, Tuncel Uzel, Mustafa Işikdoğan, İsa Dağli, Nurullah Hamİdİ, Halil Başar","doi":"10.32604/cju.2025.071101","DOIUrl":"10.32604/cju.2025.071101","url":null,"abstract":"<p><strong>Background: </strong>The European Association of Urology (EAU) recommends transperineal biopsy (TPBx) due to its lower infection risk and higher diagnostic rate for anterior zone tumors. This study aims to assess the learning curve of TPBx using the Perino-Flex® angle-adjustable needle guide under local anesthesia.</p><p><strong>Methods: </strong>A retrospective observational analysis was conducted from November 2023 to March 2024, involving 100 patients who underwent TPBx with coaxial technique under local anesthesia. Data collected included patient demographics, procedure and room times, pain levels, anxiety scores, and complications. The study focused on comparing procedure times, pain scores, and complication rates to evaluate the learning curve over time.</p><p><strong>Results: </strong>The mean room time significantly decreased from 29.55 min in the first group to 19.95 min in the fifth (p < 0.001). Procedure time was reduced from 15.25 min in the first group to 7.50 min in the fifth (p < 0.001). Visual Analog Scale (VAS) scores during core sampling demonstrated a significant decrease after the first 20 patients (2.70 vs. 0.90 in the first and second quartile, respectively, p < 0.001), indicating a rapid gain in operator proficiency. When splitting the first 20 patients into two subgroups, pain scores significantly dropped after the initial 10 cases. Cancer detection rates remained stable across all groups. Notably, no infectious complications were observed throughout the study.</p><p><strong>Conclusion: </strong>This study highlights the learning curve for TPBx with an adjustable needle guide under local anesthesia. It shows that as experience grows, pain decreases and procedure times shorten, improving both patient comfort and efficiency. These findings offer valuable guidance for new practitioners to learn more quickly and achieve better diagnostic results.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"699-707"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified versus traditional Devine procedure for pediatric concealed penis: a systematic review and meta-analysis.","authors":"Jinwei Mao, Jie Deng, Xiqi Peng, Xunbao Wang, Song Wu","doi":"10.32604/cju.2025.072113","DOIUrl":"10.32604/cju.2025.072113","url":null,"abstract":"<p><strong>Background: </strong>Concealed penis (CP) is a common congenital condition in pediatric urology, and surgical correction remains the mainstay of treatment. The modified Devine procedure (MDP) has been increasingly used, but its comparative safety and effectiveness relative to the traditional Devine procedure (TDP) remain unclear. This study aimed to compare the safety and effectiveness of the MDP with the TDP for the treatment of pediatric CP.</p><p><strong>Methods: </strong>This systematic review and meta-analysis was conducted in accordance with the PRISMA 2020 and AMSTAR guidelines. Prospective, retrospective, and randomized controlled studies comparing MDP and TDP for pediatric CP were included. Five databases (China National Knowledge Infrastructure, Medline, PubMed, Cochrane Library, and Web of Science) were searched from their inception to May 2025. Data extraction was performed independently by two authors, and discrepancies were resolved by a third reviewer. Statistical analyses were performed using Stata 16.0 software. Weighted mean difference (WMD) and odds ratio (OR) with 95% confidence intervals (CI) were calculated. Study quality and risk of bias were assessed using the Newcastle-Ottawa Scale and ROBINS-I tool.</p><p><strong>Results: </strong>Twenty-two studies describing 1512 patients were included. Compared to the TDP, the MDP had an advantage in length of stay (weighted mean difference [WMD] = -1.19, 95% CI [-1.03, -0.15], p < 0.01), estimated blood loss (WMD = -4.32, 95% CI [-7.64, -1.01], p < 0.05), prepuce oedema time (WMD = -1.37, 95% CI [-2.49, -0.25], p < 0.05), postoperative penis length (WMD = 0.52, 95% CI [0.25, 0.80], p < 0.01), postoperative penis extension length (WMD = 0.90, 95% CI [0.58, 1.22], p < 0.01), complications (odds ratio [OR] = 0.15, 95% CI [0.10, 0.24), p < 0.01), prepuce oedema (OR = 0.21, 95% CI [0.13, 0.34], p < 0.01), penile retraction (OR = 0.21, 95% CI [0.06, 0.79], p < 0.05), postoperative pain (OR = 0.18, 95% CI [0.05, 0.64], p < 0.01), satisfaction (OR = 8.35, 95% CI [2.42, 28.78], p < 0.01), and effectiveness (OR = 4.64, 95% CI [2.61, 8.26], p < 0.01). The two surgical groups were comparable in terms of operative time. Several included studies had small sample sizes, and EMBASE was initially not searched due to institutional access restrictions, which may have led to the omission of relevant studies.</p><p><strong>Conclusion: </strong>Modified Devine procedure is superior to the traditional Devine procedure in the treatment of pediatric concealed penis. However, these results should be interpreted as preliminary trends, and further randomized controlled trials with larger sample sizes are needed to validate and strengthen these observations.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"657-673"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of Sambucus nigra extract in the treatment of interstitial cystitis.","authors":"Arif Kol, Hüseyin Günizi, Özlem Ceren Günizi","doi":"10.32604/cju.2025.070231","DOIUrl":"https://doi.org/10.32604/cju.2025.070231","url":null,"abstract":"<p><strong>Objective: </strong>Sambucus nigra (SN) has been found to exhibit strong antioxidant properties and anti-inflammatory effects. In our study, we aimed to investigate the therapeutic effects of Sambucus nigra extracts (SNe) in interstitial cystitis, a condition in which inflammation plays a significant role in its pathophysiology.</p><p><strong>Methods: </strong>Thirty Wistar albino adult female rats were used in this study. All rats were housed at an average room temperature of 23°C, with a 12-h light/dark cycle, and had ad libitum access to food. The rats were divided into three groups: Group 1 (n = 10): Control (sham) group, Group 2 (n = 10): Interstitial cystitis group, and Group 3 (n = 10): Treatment group. Rats in Group 3 were administered oral Sambucus nigra extract at a dose of 0.040 g/kg every other day for a total of 8 weeks. Bladder tissues were examined both histologically and immunohistochemically, with a focus on mast cells and the presence of Interleukin-6 (IL-6), Interleukin-8 (IL-8), Vascular Endothelial Growth Factor (VEGF), and Tumor Necrosis Factor-α (TNF-α).</p><p><strong>Results: </strong>The findings of chronic inflammation were striking in the bladder sections of the interstitial cystitis group. In the treatment group, regenerating transitional epithelium, a compact appearance in the lamina propria, and a decrease in inflammatory cells and mast cells were observed. While significant improvements were noted in IL-8, TNF-α, and mast cell counts, there was a reduction in IL-6 and VEGF levels, although this reduction was not statistically significant.</p><p><strong>Conclusion: </strong>Sambucus nigra, significantly reduces TNF-α, Mast cell, VEGF, IL-6, and IL-8 levels in interstitial cystitis (IC) bladder tissue. It provides recovery in damaged bladder epithelium, smooth muscle, and basal membrane. SN attracts attention as an important agent due to its effects in the treatment of IC.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"675-684"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and racial predictors of adverse pathology at radical prostatectomy: implications for undertreatment among patients receiving radiation and hormonal therapy.","authors":"Mutlay Sayan, Yetkin Tuac, Zhiyu Qian, Alexander P Cole, Jonathan E Leeman, Martin T King, Paul L Nguyen, Anthony V D'Amico","doi":"10.32604/cju.2026.074677","DOIUrl":"https://doi.org/10.32604/cju.2026.074677","url":null,"abstract":"<p><strong>Objectives: </strong>Under-grading exists in up to 7% of patients undergoing radical prostatectomy (RP) for prostate cancer (PC). We assessed whether underrepresented race and ethnicity disproportionately increased the odds of adverse pathology at RP in patients with biopsy Gleason score 6 or 7 PC at high-risk for upgrading and/or upstaging at RP based on age and PC indices at presentation.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed 76,474 patients in the National Cancer Database (2015-2021) with biopsy Gleason score 6 or 7 N0M0 PC. Odds ratio (OR) at RP of adverse pathology defined as prostatectomy (p) Gleason score 9-10, node-positive disease, or pT3b-T4 PC in patients at high- or highest-risk for upgrading at RP. The highest-risk group comprised age > 70 years, PSA > 10 ng/mL, cT2 or higher, ≥50% positive biopsy cores, and Black or other non-White race and/or Hispanic ethnicity versus the same clinical factors and White race and non-Hispanic ethnicity for high-risk. Others were classified as low-risk.</p><p><strong>Results: </strong>The adverse pathology OR was 4.36 (95% CI, 3.10-6.89), and 2.64 (95% CI, 2.25-3.08) for patients in the high-risk and highest-risk groups respectively compared to low-risk. Highest-risk patients had a significantly higher adverse pathology OR [1.70 (95% CI, 1.11-2.60); p = 0.015] when compared to high-risk patients.</p><p><strong>Conclusions: </strong>Disproportionate under-grading and under-staging observed in under-represented minorities can lead to under-treatment in the highest-risk patients electing to undergo radiation and androgen deprivation therapy (ADT), given ADT duration could be based on under-graded PC, highlighting the urgent need to improve the detection strategy in these patients.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"583-591"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endourological autologous bypass-ureteroplasty for anastomotic atresia in orthotopic neobladder: a novel surgical approach and case report.","authors":"Ao Li, Cai Tang, Xin Wei, Feng Liu","doi":"10.32604/cju.2025.070366","DOIUrl":"https://doi.org/10.32604/cju.2025.070366","url":null,"abstract":"<p><strong>Background: </strong>Ureteroenteric anastomotic stricture is a common complication after ureteral diversion with radical cystectomy, which leads to hydronephrosis, infection, and chronic renal failure. Although ureteroneocystostomy is reliable, its high degree of invasion often causes great damage and postoperative complications in patients. Therefore, we offer a new endoscopic approach with relatively limited invasion for severe obstructions such as ureteroenteric anastomotic atresia.</p><p><strong>Case description: </strong>A 65-year-old man underwent radical cystectomy and urinary diversion of orthotopic neobladder and standardized chemotherapy for high-risk non-muscle-invasive bladder cancer. Severe left hydronephrosis was then detected due to ureteroenteric anastomotic atresia. Percutaneous nephrostomy was performed to preserve renal function. Based on our previous experience in ureteral bypass construction utilizing the Allium ureteral stent, the patient received a successful endourological autologous bypass-ureteroplasty to treat ureteroenteric anastomotic atresia in an orthotopic neobladder and maintained mild hydronephrosis with a stent-free in the follow-up.</p><p><strong>Conclusions: </strong>The case offers an innovative and promising surgical modality to overcome the limitations of the existing endourological techniques, which often require long-term placement of ureteral stents to maintain drainage and are associated with stent-related symptoms. Compared to traditional ureteroneocystostomy, endoscopic treatment offers advantages such as minimal invasiveness and fewer postoperative complications. With advancements in related techniques, endoscopic management has become a promising alternative for selected cases.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"643-648"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An outbreak of multidrug-resistant Pseudomonas aeruginosa infections following flexible ureteroscopic stone removal.","authors":"Sin Woo Lee, Seung-Kwon Choi","doi":"10.32604/cju.2025.073355","DOIUrl":"https://doi.org/10.32604/cju.2025.073355","url":null,"abstract":"<p><strong>Background: </strong>Postoperative infections are an emerging concern in endourology. This study reports an outbreak of urinary tract infections associated with Pseudomonas aeruginosa (PA) in patients who underwent stone removal surgery using flexible ureteroscopy (FURS) at Seoul Medical Center.</p><p><strong>Methods: </strong>Between August and December 2024, five patients who underwent FURS performed by the same surgeon developed postoperative febrile episodes requiring further treatment. Urine cultures from four patients revealed an outbreak of multidrug-resistant PA, prompting environmental cultures and an inspection of the instrument reprocessing procedures led by the hospital's infection control department.</p><p><strong>Results: </strong>Although PA was not isolated from the FURS itself, urine culture results showed identical antibiotic susceptibility profiles, and three patients exhibited temporal continuity, suggesting that the infections were related to surgery. No PA infections occurred among patients treated by other surgeons using single-use FURS during the same period, indicating that the infections were associated with the reusable FURS used solely by surgeon A. Environmental culturing detected PA on the sink and handle in the cleaning room, and deficiencies in the reprocessing procedures were identified. The FURS reprocessing protocol was revised to include ethylene oxide gas sterilization after each use, twice-daily disinfections of the sink where PA was identified, and replacement of handles and brushes. After implementing improvements to the reprocessing protocol, no further infections were reported over six months.</p><p><strong>Conclusions: </strong>Comprehensive device management may help prevent device related outbreaks. Given the complexity of FURS reprocessing, systematic management by trained personnel and ongoing monitoring are necessary to prevent device-associated infections.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"527-535"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clean intermittent catheterization reverses hydronephrosis in a child with congenital nephrogenic diabetes insipidus: a case report.","authors":"Jianlin Xie, Jingde Wu, Qingwei Zhang, Yuanqi Guo, Xiande Huang","doi":"10.32604/cju.2026.075856","DOIUrl":"10.32604/cju.2026.075856","url":null,"abstract":"<p><strong>Background: </strong>Congenital nephrogenic diabetes insipidus (CNDI) is most frequently caused by mutations in the AVPR2 gene. Patients exhibit persistent polyuria due to renal insensitivity to antidiuretic hormone. Chronic high urine output predisposes to bladder dysfunction and upper urinary-tract dilatation, notably hydronephrosis. Although pharmacotherapy can partially reduce urine volume, its capacity to reverse established hydronephrosis is limited. Clean intermittent catheterization (CIC), a mainstay in managing neurogenic bladder, warrants investigation regarding its utility in CNDI-associated hydronephrosis.</p><p><strong>Case description: </strong>A 9-year-old Chinese boy presented with lifelong polydipsia and polyuria, with a peak 24-h urine output of approximately 7100 mL. Renal ultrasonography demonstrated bilateral moderate hydronephrosis. Whole-exome sequencing identified a hemizygous nonsense mutation, AVPR2 c.968G>A (p.Trp323*); his mother was a heterozygous carrier of the same variant. After one month of standard therapy with hydrochlorothiazide and indomethacin, his daily urine volume decreased to approximately 3400 mL/d, but the hydronephrosis showed no improvement. A subsequent video urodynamic study revealed decreased bladder sensation, reduced compliance, and diminished detrusor contractility. In addition to the continued pharmacological regimen, clean intermittent catheterization (performed three times daily at home) was introduced. Follow-up ultrasonography one month later showed significant improvement in the bilateral hydronephrosis.</p><p><strong>Conclusions: </strong>For pediatric CNDI patients with persistent incomplete bladder emptying and hydronephrosis despite pharmacotherapy, short-term clean intermittent catheterization can break the vicious cycle of \"chronic urinary retention-elevated bladder pressure-upper urinary tract dilatation,\" representing a safe, effective, and readily implementable adjuvant intervention.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"723-728"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aquablation for LUTS due to BPH in men with localized prostate cancer.","authors":"James T Kearns, Cecilia Chang, Chi Wang, Christopher Ward, Henry M Dunnenberger, Kristian Novakovic, Alexander P Glaser, Brian T Helfand","doi":"10.32604/cju.2025.073852","DOIUrl":"10.32604/cju.2025.073852","url":null,"abstract":"<p><strong>Background: </strong>Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are common in aging men and are often concomitant. The purpose of the study was to evaluate whether Aquablation in men with BPH and early-stage PCa resulted in improvements in lower urinary tract symptoms (LUTS) and urinary quality of life (QoL) similar to men with only BPH. Furthermore, we explored active surveillance (AS) cancer outcomes in men undergoing Aquablation compared with a control AS population.</p><p><strong>Methods: </strong>Two prospective IRB (institutional review board)-approved databases were used to investigate outcomes in men with GG1 PCa on AS and men with LUTS due to BPH treated with Aquablation. Clinical and demographic data were collected. AS was performed per institutional protocol, and all men undergoing Aquablation did so for relief of symptomatic LUTS/BPH. Between-group comparisons were made using Analysis of variance, with multiple pairwise comparisons or Chi-squared tests were used to compare baseline demographics. Urinary outcomes at baseline, 6 weeks, and 6 months were compared between subgroups using t-tests.</p><p><strong>Results: </strong>1445 men were included in the analysis: 914 on AS, 478 without PCa who underwent Aquablation, and 53 on AS who underwent Aquablation. Aquablation resulted in significant improvement in IPSS, QoL, and Qmax in both groups undergoing Aquablation. AS patients who underwent Aquablation had 44% fewer pathologic upgrading events than AS patients who did not undergo Aquablation. This corresponds to a freedom from progression hazard ratio of 0.48 (95%CI [0.24, 0.98], p = 0.044).</p><p><strong>Conclusions: </strong>Aquablation is safe and effective for the treatment of LUTS due to BPH in men on AS for early-stage prostate cancer. Additionally, Aquablation in men undergoing AS is associated with a lower risk of pathologic upgrading and favorably alters the oncologic outcomes.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"555-562"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prostatic tuberculosis incidentally discovered during transurethral resection of prostate with subsequent diagnosis of rectal and pulmonary involvement: a case report.","authors":"Shao-Chen Su, Yi-Sheng Lin, Zhon-Min Huang, Chao-Yu Hsu, Yen-Chuan Ou","doi":"10.32604/cju.2025.073769","DOIUrl":"https://doi.org/10.32604/cju.2025.073769","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is a globally prevalent infectious disease, including in Taiwan. Prostatic TB is a rare manifestation of genitourinary tuberculosis (GU-TB), which is the third most common extrapulmonary form of the disease. However, due to its insidious onset and non-specific symptoms, prostatic TB is often diagnosed late.</p><p><strong>Case description: </strong>We report a case of a 72-year-old male patient who presented with lower urinary tract symptoms (LUTS) and painful scrotal swelling. Following transurethral resection of the prostate (TURP), histopathological examination revealed prostatic TB. The patient subsequently had abdominal cramping and diarrhea. A colonoscopy detected an ulcer-like lesion in the rectum, indicating mycobacterial infection and cytomegalovirus colitis. Chest computed tomography revealed pulmonary involvement, and the patient was started on a six-month course of anti-TB treatment.</p><p><strong>Conclusions: </strong>This case highlights the importance of considering TB in the differential diagnosis of LUTS and highlights the need for screening for other potential sites of involvement, particularly in the lungs, when a diagnosis of prostatic TB is made.</p>","PeriodicalId":520500,"journal":{"name":"The Canadian journal of urology","volume":"33 3","pages":"709-717"},"PeriodicalIF":0.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}