Journal of plastic and reconstructive surgery最新文献

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Delayed Presentation of a Middle Meningeal Arteriovenous Fistula after Le Fort I Osteotomy. Le Fort I型截骨术后延迟出现中脑膜动静脉瘘。
Journal of plastic and reconstructive surgery Pub Date : 2024-07-05 eCollection Date: 2024-10-27 DOI: 10.53045/jprs.2023-0019
Sean Neo, Hui-Chai Fong, Boon Hui Chan, Chee Liam Foo
{"title":"Delayed Presentation of a Middle Meningeal Arteriovenous Fistula after Le Fort I Osteotomy.","authors":"Sean Neo, Hui-Chai Fong, Boon Hui Chan, Chee Liam Foo","doi":"10.53045/jprs.2023-0019","DOIUrl":"10.53045/jprs.2023-0019","url":null,"abstract":"<p><p>While rare, complications following Le Fort I maxillary osteotomy includes hemorrhage, ischemia, infection, and vascular abnormalities. This study aimed to present an uncommon case of delayed presentation of a middle meningeal pseudoaneurysm formation after Le Fort I osteotomy. The patient initially presented with pulsatile tinnitus, and the pseudoaneurysm was subsequently treated successfully with image-guided embolization.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 4","pages":"165-167"},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraarticular Involvement of Extraarticular Giant Cell Tumor of the Tendon Sheath in the Thumb of a Pediatric Patient: A Case Report. 小儿拇指腱鞘关节外巨细胞瘤累及关节内1例报告。
Journal of plastic and reconstructive surgery Pub Date : 2024-07-05 eCollection Date: 2025-01-27 DOI: 10.53045/jprs.2024-0004
Aiko Makino, Susumu Saito, Tsuyoshi Taba
{"title":"Intraarticular Involvement of Extraarticular Giant Cell Tumor of the Tendon Sheath in the Thumb of a Pediatric Patient: A Case Report.","authors":"Aiko Makino, Susumu Saito, Tsuyoshi Taba","doi":"10.53045/jprs.2024-0004","DOIUrl":"10.53045/jprs.2024-0004","url":null,"abstract":"<p><p>Giant cell tumors of the tendon sheath (GCTTS) are locally invasive and have a high likelihood of recurrence in adults, but it is rare in children. Its potential to be invasive or recur has not been characterized. We present a 9-year-old patient with a dumbbell-shaped GCTTS that had small intraarticular and large extraarticular components with a narrow connection between them. This case suggests that GCTTS can be locally invasive in children. This case report could help hand surgeons who treat GCTTS in children.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"4 1","pages":"46-49"},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Glomus Tumor of the Anterior Neck. 前颈部血管球瘤1例。
Journal of plastic and reconstructive surgery Pub Date : 2024-06-07 eCollection Date: 2024-10-27 DOI: 10.53045/jprs.2023-0027
Kahoko Yamada, Nobuyuki Mitsukawa
{"title":"A Case of Glomus Tumor of the Anterior Neck.","authors":"Kahoko Yamada, Nobuyuki Mitsukawa","doi":"10.53045/jprs.2023-0027","DOIUrl":"10.53045/jprs.2023-0027","url":null,"abstract":"<p><p>A 54-year-old woman presented with an anterior neck subcutaneous tumor that had appeared one month prior. Mild tenderness was noted. As a diagnosis was difficult to make based on physical examination and ultrasonography, a magnetic resonance imaging (MRI) scan was performed. Both examinations revealed a 1-cm subcutaneous mass with well-defined margins; the MRI scan was hypointense on T1-weighted images and slightly hyperintense with low point foci on T2-weighted images. Subsequently, an excisional biopsy was performed, and the pathologic diagnosis of glomus tumor was obtained. Glomus tumors usually present as a painful subcutaneous mass beneath the nail bed but may be painless or occur in areas other than the fingers. Because glomus tumors in the neck resemble a variety of diseases, their diagnosis may be delayed. This case highlights the importance of considering glomus tumors as a potential cause of neck subcutaneous tumors.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 4","pages":"175-178"},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Perineurioma Recurring in the Mandible. 下颌骨骨膜瘤复发1例。
Journal of plastic and reconstructive surgery Pub Date : 2024-06-07 eCollection Date: 2025-01-27 DOI: 10.53045/jprs.2023-0054
Kyoko Baba, Yuuta Niimi, Shun Imamura, Ami Kuwabara, Shunichiro Ego, Mitsuru Nemoto, Yasuharu Yamazaki, Akira Takeda
{"title":"A Case of Perineurioma Recurring in the Mandible.","authors":"Kyoko Baba, Yuuta Niimi, Shun Imamura, Ami Kuwabara, Shunichiro Ego, Mitsuru Nemoto, Yasuharu Yamazaki, Akira Takeda","doi":"10.53045/jprs.2023-0054","DOIUrl":"10.53045/jprs.2023-0054","url":null,"abstract":"<p><p>Perineuriomas (PNs) are soft tissue tumors originating from the perineurium. We report the case of a 51-year-old man who presented with a right mandibular mass. Initial examination revealed a palpable, painless, solid mass at the right mandibular angle. Preoperative computed tomography revealed a highly absorbent mass with uneven staining margins in contact with the mandible. Surgery was performed under general anesthesia for diagnosis, and a well-defined solid tumor of 8 cm was excised. Subsequently, immunohistological staining revealed that the tumor was diagnosed with perineuriomas recurrence of mental nerve origin. This is the first report on perineuriomas of mental nerve origin and the third report on recurrent perineuriomas. Our findings highlight the need for immunohistological staining of tumors for perineuriomas diagnosis, and follow-up observation might be recommended given the risk of recurrence.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"4 1","pages":"50-56"},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum-free Quality and Quantity Control Culture Improves the Angiogenic Potential of Peripheral Blood Mononuclear Cells Harvested from Patients with Connective Tissue Diseases. 无血清质量和数量控制培养提高结缔组织疾病患者外周血单个核细胞的血管生成潜能
Journal of plastic and reconstructive surgery Pub Date : 2024-05-10 eCollection Date: 2024-10-27 DOI: 10.53045/jprs.2022-0050
Satomi Furukawa, Rie Hirano, Ai Sugawara, Satoshi Fujimura, Rica Tanaka
{"title":"Serum-free Quality and Quantity Control Culture Improves the Angiogenic Potential of Peripheral Blood Mononuclear Cells Harvested from Patients with Connective Tissue Diseases.","authors":"Satomi Furukawa, Rie Hirano, Ai Sugawara, Satoshi Fujimura, Rica Tanaka","doi":"10.53045/jprs.2022-0050","DOIUrl":"10.53045/jprs.2022-0050","url":null,"abstract":"<p><strong>Objectives: </strong>The number and quality of endothelial progenitor cells decrease in patients with connective tissue diseases. This limits the efficacy of mononuclear cell therapy for ischemic ulcers associated with connective tissue diseases. To overcome these problems, we developed a serum-free quality and quantity control culture method that potentially improves the function of endothelial progenitor cells and expands their numbers. Here, we show the effect of quality and quantity control culture on mononuclear cells from patients with connective tissue diseases.</p><p><strong>Methods: </strong>Peripheral blood mononuclear cells were isolated from C57BL/6JJmsSlc-<i>lpr/lpr</i> mice with systemic lupus erythematosus, patients with connective tissue diseases, and healthy volunteers. Mononuclear cells were cultured using the quality and quantity control culture method, and the number of endothelial progenitor cells was analyzed using flow cytometry, an endothelial progenitor cell culture assay, and an endothelial progenitor cell colony-forming assay. Flow cytometry was also used to examine mononuclear cell subpopulations. A human umbilical vein endothelial cell tube-forming assay was used to examine the function of quality and quantity control cultured mononuclear cells.</p><p><strong>Results: </strong>Mice with systemic lupus erythematosus showed a significantly lower number of endothelial progenitor cells, which increased to the same levels as those of the control mice after quality and quantity control culture. In humans, the numbers of endothelial progenitor cells and M2 macrophages were significantly increased and the number of proinflammatory cells was decreased after quality and quantity control culture in both healthy volunteers and patients with connective tissue diseases. The human umbilical vein endothelial cell tube formation assay showed higher angiogenic potential in quality and quantity control cultured mononuclear cells from patients with connective tissue diseases than that in quality and quantity control cultured mononuclear cells from healthy controls.</p><p><strong>Conclusions: </strong>Our study suggests that the quality and quantity control culture method is effective in recovering the angiogenic ability of mononuclear cells from patients with connective tissue diseases.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 4","pages":"157-164"},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of the "Flange Joint" Anastomotic Technique for Hepatic Artery Reconstruction in Liver Transplantation. “法兰关节”吻合技术在肝移植肝动脉重建中的应用。
Journal of plastic and reconstructive surgery Pub Date : 2024-05-10 eCollection Date: 2024-07-27 DOI: 10.53045/jprs.2023-0024
Hui-Chai Fong, Jonathan Tw Au Eong, Khong-Yik Chew, Ye-Xin Koh, Jeyaraj Prema Raj, Bien-Keem Tan
{"title":"The Use of the \"Flange Joint\" Anastomotic Technique for Hepatic Artery Reconstruction in Liver Transplantation.","authors":"Hui-Chai Fong, Jonathan Tw Au Eong, Khong-Yik Chew, Ye-Xin Koh, Jeyaraj Prema Raj, Bien-Keem Tan","doi":"10.53045/jprs.2023-0024","DOIUrl":"10.53045/jprs.2023-0024","url":null,"abstract":"<p><strong>Objectives: </strong>A successful liver transplantation requires hepatic artery inflow reconstitution. In living donor liver transplantation, there are additional challenges in the form of a short and small-caliber donor vessel stump, exacerbating the challenges of microsurgery. Meanwhile, in deceased donor liver transplantation, vessel diameter mismatch remains a potential challenge since the liver graft is procured with a long segment of the celiac axis with branches of differing calibers. Other challenges include the poor condition of the recipient vessels due to previous trans-arterial chemoembolization or radiofrequency ablation. We present an illustrated report of our anastomosis technique utilizing a \"flange-joint\" to increase the luminal diameter of the recipient vessel while minimizing the risk of vessel wall separation.</p><p><strong>Methods: </strong>Ten patients had hepatic reconstruction with our \"flange-joint\" anastomosis technique. The indications for this technique were poor vessel quality with fibrosis and/or previous trans-arterial chemoembolization (n = 5) and vessel size mismatch (n = 5).</p><p><strong>Results: </strong>All patients had successful reconstitution of hepatic arterial inflow. The average post-operative resistive index was 0.66 [0.52-0.79]. The average follow-up was 11.7 months [1-27] with no biliary complications.</p><p><strong>Conclusions: </strong>We propose that the distal tied-off branches of the recipient artery be splayed open to provide an expanded vessel end. This allows for increased flexibility in tailoring the vessel end to match the caliber of the donor artery, thereby overcoming vessel caliber mismatch.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 3","pages":"104-109"},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors of 30-day Hospital Readmission after Autologous vs. Implant-based Breast Reconstruction: A 16-year Analysis of 175,474 Patients. 自体乳房重建与假体乳房重建术后30天再入院的预测因素:对175,474例患者的16年分析
Journal of plastic and reconstructive surgery Pub Date : 2024-05-10 eCollection Date: 2024-10-27 DOI: 10.53045/jprs.2023-0066
Isabella L Lipkin, Renxi Li, Bharat G Ranganath
{"title":"Predictors of 30-day Hospital Readmission after Autologous vs. Implant-based Breast Reconstruction: A 16-year Analysis of 175,474 Patients.","authors":"Isabella L Lipkin, Renxi Li, Bharat G Ranganath","doi":"10.53045/jprs.2023-0066","DOIUrl":"10.53045/jprs.2023-0066","url":null,"abstract":"<p><strong>Objectives: </strong>Comorbidities that impair wound healing, increase infection risk, and compromise tissue viability influence rates of hospital readmission after autologous reconstruction and implant-based reconstruction. This study aimed to evaluate patient factors that increase risk for 30-day hospital readmission after autologous reconstruction and implant-based reconstruction and identify differences in the comorbidities that affect readmission risk after each method.</p><p><strong>Methods: </strong>Patients from 2005 to 2021 were selected by autologous reconstruction and implant-based reconstruction current procedural terminology codes from the American College of Surgeons National Surgical Quality Improvement Program database. A multivariable regression model identified the significant predictors of unplanned readmission.</p><p><strong>Results: </strong>Comorbidities that increase risk for readmission after autologous reconstruction but not implant-based reconstruction include dialysis (OR 3.87, p = 0.042) and malnutrition (OR 3.20, p = 0.003). Risk factors for readmission after implant-based reconstruction but not autologous reconstruction include bleeding disorder (OR 2.62, p < 0.0001), previous infection (OR 1.49, p = 0.045), recent sepsis (OR 2.16 p = 0.0003), anemia (OR 1.13, p = 0.0018), and hypoalbuminemia (OR 1.35, p = 0.0213). Predictors of unplanned readmission after both methods include chronic obstructive pulmonary disorder, obesity, inpatient status prior to procedure, Black or White race, chronic steroid use, smoking, diabetes, and hypertension.</p><p><strong>Conclusions: </strong>These findings may be used to individualize preoperative discussions and help guide optimization of risk factors. In addition, while autologous reconstruction and implant-based reconstruction are often combined into one category for discussion of factors that increase complication risk, our study suggests that the types of reconstruction differ with regard to the comorbidities that increase risk for hospital readmission.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 4","pages":"142-150"},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics. 顽固性脓肿分枝杆菌感染:手术加门诊抗生素联合治疗皮肤软组织感染复发。
Journal of plastic and reconstructive surgery Pub Date : 2024-04-06 eCollection Date: 2024-10-27 DOI: 10.53045/jprs.2023-0055
Atsuki Yamada, Ken Yukawa, Tomoaki Eguchi
{"title":"Refractory Infection of <i>Mycobacterium abscessus</i>: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics.","authors":"Atsuki Yamada, Ken Yukawa, Tomoaki Eguchi","doi":"10.53045/jprs.2023-0055","DOIUrl":"10.53045/jprs.2023-0055","url":null,"abstract":"<p><p><i>Mycobacterium abscessus</i> (<i>M. abscessus</i>) is a nontuberculous mycobacterium that causes skin and soft tissue infections. Treatment methods for these infections, including the type and duration of antimicrobial agents, have not been established. The function of surgery is also unknown. We report a case of skin and soft tissue infection of the left upper arm in a healthy 47-year-old Japanese man who was treated with complete surgical excision and antimicrobial therapy as feasible on an outpatient basis, which resulted in relapse <1 month later. Given the possibility of developing antibiotic-resistant bacteria, insufficient antimicrobial treatment should not be administered without careful consideration. There are currently few effective oral antimicrobial agents against <i>M. abscessus</i>, so careful antimicrobial therapy along with hospitalization (at least during the early treatment phase) is preferred, regardless of the use/nonuse of surgical treatment.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 4","pages":"168-174"},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The First National Survey of Endoscopic Plastic Surgery by the Japan Society of Plastic and Reconstructive Surgery 2020-2021. 日本整形与重建外科学会2020-2021年第一次全国内窥镜整形外科调查。
Journal of plastic and reconstructive surgery Pub Date : 2024-04-06 eCollection Date: 2024-10-27 DOI: 10.53045/jprs.2023-0040
Kazunobu Hashikawa, Toshihiko Satake, Yuko Asano, Tsutomu Kashimura, Shimpei Ono, Tomoyuki Yano, Yoshikazu Inoue, Kyoko Dogo, Hideki Kadota, Shimpei Miyamoto, Tetsuji Uemura
{"title":"The First National Survey of Endoscopic Plastic Surgery by the Japan Society of Plastic and Reconstructive Surgery 2020-2021.","authors":"Kazunobu Hashikawa, Toshihiko Satake, Yuko Asano, Tsutomu Kashimura, Shimpei Ono, Tomoyuki Yano, Yoshikazu Inoue, Kyoko Dogo, Hideki Kadota, Shimpei Miyamoto, Tetsuji Uemura","doi":"10.53045/jprs.2023-0040","DOIUrl":"10.53045/jprs.2023-0040","url":null,"abstract":"<p><strong>Objectives: </strong>No detailed country-specific cross-sectional studies have been reported on endoscopic plastic surgery. For the first time, the Japan Society of Plastic and Reconstructive Surgery conducted a nationwide survey to ascertain the status of endoscopic procedures in plastic surgery in Japan. This article discusses the current situation based on this survey findings.</p><p><strong>Methods: </strong>A questionnaire survey was conducted among 566 Japan Society of Plastic and Reconstructive Surgery-certified training facilities regarding the status of endoscopic plastic surgery procedures completed between January 2020 and December 2021.</p><p><strong>Results: </strong>Of the 143 institutions, 33 conducted endoscopic plastic surgery operations during the period, for a total of 753 procedures. Two hundred sixty-two procedures were conducted in the craniomaxillofacial region at 19 institutions and 491 in the extremities and trunk region at 19 institutions. Five intraoperative accidents were recorded, but no cases were moved to traditional surgery based on intraoperative choices. Sixteen postoperative problems were reported, but there were no reports of fatalities.</p><p><strong>Conclusions: </strong>The number of endoscopic plastic surgery cases is anticipated to rise, and this nationwide survey will contribute to this by offering useful data and insights.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 4","pages":"138-141"},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Salvage Therapy of Late-onset Arterial Disorders due to Recurrent Vasospasms Following Free Flap Transfer under the IL-6 and TNF-α Signaling-downregulated Environment: A Case Report. IL-6和TNF-α信号下调环境下自由皮瓣移植后复发性血管痉挛引起的迟发性动脉疾病的成功挽救治疗:1例报告
Journal of plastic and reconstructive surgery Pub Date : 2024-03-01 eCollection Date: 2024-04-27 DOI: 10.53045/jprs.2023-0049
Jun-Ya Niwa, Koichi Gonda, Kazufumi Tachi
{"title":"Successful Salvage Therapy of Late-onset Arterial Disorders due to Recurrent Vasospasms Following Free Flap Transfer under the IL-6 and TNF-α Signaling-downregulated Environment: A Case Report.","authors":"Jun-Ya Niwa, Koichi Gonda, Kazufumi Tachi","doi":"10.53045/jprs.2023-0049","DOIUrl":"10.53045/jprs.2023-0049","url":null,"abstract":"<p><p>A 77-year-old woman who had been taking iguratimod and sarilumab for rheumatoid arthritis for 3 months had gas gangrene. After hospitalization, she underwent two debridement surgeries, one drainage procedure, and a free latissimus dorsi musculocutaneous flap transfer for the resulting tissue defect on the oral cavity through the temple. Following the free flap surgery, she experienced flap ischemia, possibly caused by the vasospasms of the intraflap and recipient arteries on postoperative days 5 and 6. These immunomodulating drugs might cause vasospasms by downregulating the interleukin-6 and/or tumor necrosis factor-α signaling pathway(s). Recent developments in antirheumatic drug therapy have increased the chances of performing microvascular surgeries on patients with inhibited immune systems, and this trend will continue or will be reinforced in the future. Close monitoring of the biochemical and clinical status of the microvascular environment is necessary.</p>","PeriodicalId":520467,"journal":{"name":"Journal of plastic and reconstructive surgery","volume":"3 2","pages":"83-88"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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