NEW ZEALAND JOURNAL OF HISTORY最新文献

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IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 2020-08-10 DOI: 10.1515/9783110610185-003
E. Hanson
{"title":"Commentary","authors":"E. Hanson","doi":"10.1515/9783110610185-003","DOIUrl":"https://doi.org/10.1515/9783110610185-003","url":null,"abstract":"High-dose methotrexate–induced nephrotoxicity is a medical emergency. Renal methotrexate excretion, which typically accounts for 90% of the drug’s elimination, is delayed, resulting in prolonged exposure to high methotrexate concentrations. The duration of exposure is the primary determinant of the drug’s toxic effects, and early recognition and prompt efforts to lower methotrexate concentrations are critical to preventing severe systemic toxicity. High-dose methotrexate–induced renal dysfunction is heralded by an increasing serum creatinine concentration during or shortly after the methotrexate infusion. Urine output is usually maintained despite a rapid decline in glomerular filtration. Daily monitoring of serum creatinine and methotrexate concentrations is essential to early detection of this complication. Leucovorin provides a source of the tetrahydrofolates that are depleted by methotrexate’s inhibition of dihydrofolate reductase, but methotrexate competes with leucovorin for cell uptake. Therefore, leucovorin rescue is less effective at methotrexate concentrations that exceed 10 mol/L for 48 h. The leucovorin dose must be increased in proportion to the serum methotrexate concentration when methotrexate clearance is delayed (e.g., 1000 mg/m every 6 h for a methotrexate concentration 10 mol/L at 48 h). High leucovorin doses (250 mg/m every 6 h) should also be continued for 48 h after glucarpidase administration because the enzyme hydrolyzes leucovorin and its active circulating metabolite, 5-methyltetrahydrofolate, to inactive forms. Glucarpidase rapidly and efficiently lowers the serum methotrexate concentration by providing an alternative route of elimination and, when administered as soon as possible after the recognition of nephrotoxicity, can effectively prevent methotrexate toxicity. Patients who receive inadequate leucovorin rescue or receive glucarpidase 96 h after the start of the methotrexate infusion are at greater risk for developing lifethreatening methotrexate toxicity (1 ). As illustrated by the case study, commercial methotrexate assays will underestimate the impact of glucarpidase on serum methotrexate concentrations because of the interference by the inactive byproduct, DAMPA. DAMPA is subsequently metabolized by hydroxylation and glucuronide conjugation and is cleared more rapidly than residual methotrexate.","PeriodicalId":51937,"journal":{"name":"NEW ZEALAND JOURNAL OF HISTORY","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/9783110610185-003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43247924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Empire settlement and single British women as New Zealand domestic servants during the 1920s. 20世纪20年代,帝国殖民和单身英国女性作为新西兰的家仆。
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 2001-01-01
K Pickles
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引用次数: 0
Population ageing among non-Maori New Zealanders in later Victorian times: a quirk of immigrant settlement history? 维多利亚时代晚期新西兰非毛利人的人口老龄化:移民定居史上的一个怪癖?
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 2001-01-01
B Heenan
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引用次数: 0
Thrips (Thysanoptera) pollination in Australian subtropical rainforests, with particular reference to pollination of Wilkiea huegeliana (Monimiaceae) 澳大利亚亚热带雨林中Thrips (Thysanoptera)的传粉,特别提到了wilkia huegeliana (Monimiaceae)的传粉
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 2001-01-01 DOI: 10.1080/002229301447853
G. Williams, P. Adam, L. Mound
{"title":"Thrips (Thysanoptera) pollination in Australian subtropical rainforests, with particular reference to pollination of Wilkiea huegeliana (Monimiaceae)","authors":"G. Williams, P. Adam, L. Mound","doi":"10.1080/002229301447853","DOIUrl":"https://doi.org/10.1080/002229301447853","url":null,"abstract":"Approximately 23 species of thrips were recorded from flowers of 26 species of Australian subtropical rainforest trees, shrubs and vines (in 17 families) in the Manning Valley, coastal northern New South Wales. Pollination by thrips (thripophily) appears more widespread in rainforest communities than has been previously recognized. The pollination ecology of Wilkiea huegeliana (Monimiaceae) was studied in detail. Wilkiea huegeliana is a small, unisexual, annually flowering tree or shrub of rainforest and associated ecotones in eastern Australia, and is a larval food plant for the Regent Skipper butterfly Euschemon rafflesia rafflesia (Hesperiidae). At this latitude W. huegeliana is pollinated solely by a species of thrips, Thrips setipennis, but T. setipennis is not restricted to W. huegeliana and was recorded from flowers of 13 rainforest plant species. It appears to be the obligate pollinator also for Rapanea howittiana and R. variabilis (Myrsinaceae). Pollinator exclusion experiments were inconclusive but W. huegeliana may be facultatively agamospermous. The recruitment pathway to unrewarding female W. huegeliana flowers is uncertain but attraction may function by automimicry. Both male and female flowers serve as brood sites for T. setipennis larvae. Although the pollination ecology of W. huegeliana is specialized, the family Monimiaceae exhibits a broad diversity of pollination strategies. A number of these are discussed. The apparent obligate and restricted pollinator requirements of W. huegeliana may make it, and any associated phytophagous fauna, vulnerable to the impacts of habitat fragmentation.","PeriodicalId":51937,"journal":{"name":"NEW ZEALAND JOURNAL OF HISTORY","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/002229301447853","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59307529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
"A good idea of colonial life": personal letters and Irish migration to New Zealand. “殖民生活的好想法”:私人信件和爱尔兰移民到新西兰。
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 2001-01-01
A McCarthy
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引用次数: 0
Maori health and Heaton Rhodes as minister of public health, 1912-1915. 毛利人卫生和希顿·罗兹担任公共卫生部长,1912-1915年。
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 2001-01-01
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引用次数: 0
Rural myth and urban actuality: the anatomy of all black and New Zealand rugby 1884-1938. 乡村神话和城市现实:1884-1938年所有黑人和新西兰橄榄球的剖析。
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 2001-01-01
G Ryan
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引用次数: 0
"Chastising its people with scorpions": Maori and the 1913 smallpox epidemic. “用蝎子惩罚它的人民”:毛利人和1913年天花疫情。
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 1999-01-01
A Day
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引用次数: 0
"Drug-besotten, sin-begotten fiends of filth": New Zealanders and the Oriental other, 1850-1920. “吸毒成瘾、罪恶滋生的污秽之魔”:新西兰人和东方人,1850-1920。
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 1999-01-01
B Moloughney, J Stenhouse
{"title":"\"Drug-besotten, sin-begotten fiends of filth\": New Zealanders and the Oriental other, 1850-1920.","authors":"B Moloughney, J Stenhouse","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":51937,"journal":{"name":"NEW ZEALAND JOURNAL OF HISTORY","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40116670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Constructing homes: gender and advertising in "Home and Building," 1936-1970. 建造房屋:性别与广告,《家与建筑》1936-1970。
IF 0.2 4区 历史学
NEW ZEALAND JOURNAL OF HISTORY Pub Date : 1999-01-01
L Shaw, B Brookes
{"title":"Constructing homes: gender and advertising in \"Home and Building,\" 1936-1970.","authors":"L Shaw, B Brookes","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":51937,"journal":{"name":"NEW ZEALAND JOURNAL OF HISTORY","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30235664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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