Berliner Journal Fur Soziologie最新文献_第3页

Last Word on Viewpoint: Do we need to change the guideline values for determining low bone mineral density in athletes? 观点的最后一句话：我们是否需要改变确定运动员骨质密度低的指导值？

IF 3.3 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-05-01 DOI: 10.1152/japplphysiol.00227.2022

Kristin L Jonvik, Monica K Torstveit, Jorunn K Sundgot-Borgen, Therese Fostervold Mathisen

引用次数: 0

Molecular mechanisms of aberrant neutrophil differentiation in glycogen storage disease type Ib. 糖原贮积病 Ib 型中性粒细胞异常分化的分子机制

IF 8 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-04-18 DOI: 10.1007/s00018-022-04267-5

Sang Wan Sim, Yuyeon Jang, Tae Sub Park, Byung-Chul Park, Young Mok Lee, Hyun Sik Jun

{"title":"Molecular mechanisms of aberrant neutrophil differentiation in glycogen storage disease type Ib.","authors":"Sang Wan Sim, Yuyeon Jang, Tae Sub Park, Byung-Chul Park, Young Mok Lee, Hyun Sik Jun","doi":"10.1007/s00018-022-04267-5","DOIUrl":"10.1007/s00018-022-04267-5","url":null,"abstract":"Glycogen storage disease type Ib (GSD-Ib), characterized by impaired glucose homeostasis, neutropenia, and neutrophil dysfunction, is caused by a deficiency in glucose-6-phosphate transporter (G6PT). Neutropenia in GSD-Ib has been known to result from enhanced apoptosis of neutrophils. However, it has also been raised that neutrophil maturation arrest in the bone marrow would contribute to neutropenia. We now show that G6pt-/- mice exhibit severe neutropenia and impaired neutrophil differentiation in the bone marrow. To investigate the role of G6PT in myeloid progenitor cells, the G6PT gene was mutated using CRISPR/Cas9 system, and single cell-derived G6PT-/- human promyelocyte HL-60 cell lines were established. The G6PT-/- HL-60s exhibited impaired neutrophil differentiation, which is associated with two mechanisms: (i) abnormal lipid metabolism causing a delayed metabolic reprogramming and (ii) reduced nuclear transcriptional activity of peroxisome proliferator-activated receptor-γ (PPARγ) in G6PT-/- HL-60s. In this study, we demonstrated that G6PT is essential for neutrophil differentiation of myeloid progenitor cells and regulates PPARγ activity.","PeriodicalId":51909,"journal":{"name":"Berliner Journal Fur Soziologie","volume":"28 1","pages":"246"},"PeriodicalIF":8.0,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11071875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80191598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wie entstehen Märkte? Ein Vergleich idealtypischer Erklärungsansätze in Ökonomie und Wirtschaftssoziologie 市场是如何形成的?经济学和经济学指导方面的最佳解释方法的比较

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-04-12 DOI: 10.1007/s11609-022-00467-9

Patrik Aspers, Petter Bengtsson, Alexander Dobeson

引用次数: 0

Abseits der Norm? Egalitäre Teilzeitarrangements während des Elterngeldbezuges. Ausgestaltung und Motivlagen 不正常？父母福利期间的平等兼职安排。设计和图案

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-04-11 DOI: 10.1007/s11609-022-00468-8

Ricarda Reich

引用次数: 0

Was bedeutet Systemrelevanz in Zeiten der Pandemie? 在流行病持续的情况下，系统重要性意味着什么?

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-03-01 DOI: 10.1007/s11609-022-00464-y

David Kaldewey

引用次数: 1

Zirkulierendes Wissen. Didaktische Lernmaterialien als Objekte trans-epistemischer Kooperation 传播知识。作为跨认识合作对象的教学材料

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-03-01 DOI: 10.1007/s11609-022-00463-z

Torsten Cress, H. Kalthoff

引用次数: 1

Eine Neuordnung der Zeit? Zum Verhältnis von Zeitlichkeit, Kapitalismus und Staat im Zeichen der Pandemie 时间安排和时代，资本主义和政府之间的关系大流行病

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-03-01 DOI: 10.1007/s11609-022-00466-w

Lisa Suckert

引用次数: 1

Begrenzte Möglichkeiten. Zur Kommerzialisierung und Akademisierung der Intellektuellenrolle 可能性有限。论智力角色的商业化与学术化

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-03-01 DOI: 10.1007/s11609-022-00465-x

Susanne Martin

引用次数: 0

[Deglobalization, reconfiguration, or business as usual? COVID-19 and the limits of reshoring of globalized productionDéglobalisation, reconfiguration ou business as usual ? COVID-19 et les limites de la relocalisation de production mondialisée]. 去全球化，重新配置，还是一切照旧?2019冠状病毒病与全球化生产回流的局限性?2019冠状病毒病(COVID-19)对生产重新本地化的限制[m]。

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-01-01 DOI: 10.1007/s11609-022-00479-5

Florian Butollo, Cornelia Staritz

{"title":"[Deglobalization, reconfiguration, or business as usual? COVID-19 and the limits of reshoring of globalized productionDéglobalisation, reconfiguration ou business as usual ? COVID-19 et les limites de la relocalisation de production mondialisée].","authors":"Florian Butollo, Cornelia Staritz","doi":"10.1007/s11609-022-00479-5","DOIUrl":"https://doi.org/10.1007/s11609-022-00479-5","url":null,"abstract":"The economic difficulties following the COVID-19 pandemic have seemingly reinforced the need for geographic restructuring and a reshoring of production, as they have demonstrated the vulnerability of globalized production. This article provides an assessment of the impact of COVID-19 on the geographies of production. Criticizing overly simplified perspectives on globalization, the article argues that global production networks are multiscalar and politically shaped phenomena. Based on these theoretical considerations and case studies on the automotive, electronics and clothing industries, the article concludes that the COVID-19 pandemic cannot be interpreted as a trigger for a general retreat from global manufacturing, but it reinforced longer-standing shifts toward more multipolar production and consumption structures. While the issue of global production network resilience has attracted greater attention in corporate strategies and industrial policies, the localization and regionalization of production networks is only one of several strategies, and it has hardly been implemented so far. Ongoing disruptions of supply chains, increased transport costs, and, above all, geopolitically and environmentally motivated policies could well lead to greater re- or nearshoring. Political efforts in this direction are, however, limited by pre-existing global economic development paths and the balance of power associated with them. In the conclusions, the article stresses the necessity of a politically motivated restructuring of global production networks in the context of an urgently needed social-ecological transformation.","PeriodicalId":51909,"journal":{"name":"Berliner Journal Fur Soziologie","volume":"32 3","pages":"393-425"},"PeriodicalIF":1.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10266480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

[Corona and globalization: Arrested developmentCorona et la mondialisation enchaînée]. [电晕与全球化:发展停滞]。

IF 1.1 3区社会学

Berliner Journal Fur Soziologie Pub Date : 2022-01-01 Epub Date: 2021-07-13 DOI: 10.1007/s11609-021-00437-7

Ulrich Menzel

{"title":"[Corona and globalization: Arrested developmentCorona et la mondialisation enchaînée].","authors":"Ulrich Menzel","doi":"10.1007/s11609-021-00437-7","DOIUrl":"https://doi.org/10.1007/s11609-021-00437-7","url":null,"abstract":"The term \"globalization\" doesn't refer to a current epoch of world history, but to an undulated process interrupted by harsh setbacks. Its phases of upswing are characterized by exponential growth. They end when tipping points arrive. For globalization inevitably has its winners and losers, these phases are paralleled by processes of fragmentation in other countries, macro-regions and societies. The article provides a sketch of both types of processes, illustrated by examples from world history. It thereby shows that they must not be considered mere byproducts of technological development in transport and communication, but also depend on institutions that guarantee \"International Public Goods\" (IPGs), above all safety, stability and connectivity. Only great powers can provide this type of goods, for only they have the resources to do so, then again for only they are confronted with a volunteer's dilemma. Moreover globalization depends on a grand narrative that marginalizes competing schools of thought. Crises emerge either when transactions driving the process reach a tipping point, or when great powers decline and are no longer ready or able to provide IPGs. Now critical discourses emerge and become hegemonic in the face of successive crises undermining the grand narrative. This results in social division between cosmopolitans and populists. Both \"big players\" currently face different dilemmas conditioned by their positions as hegemonic power (USA) and freerider (China), in each case causing them to act neo-isolationist. The result: IPGs are no longer guaranteed, globalization is in crisis. This development has been catalysed by the Corona-pandemic.","PeriodicalId":51909,"journal":{"name":"Berliner Journal Fur Soziologie","volume":" ","pages":"363-392"},"PeriodicalIF":1.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11609-021-00437-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39198889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3