The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology最新文献

{"title":"Diagnosis of liver fibrosis in patients with hepatitis B-related liver disease using ultrasound with wave-number domain attenuation coefficient.","authors":"Danqing He,&nbsp;Chaoxue Zhang,&nbsp;Wenqian Qiu,&nbsp;Qinxiu Xie","doi":"10.5152/tjg.2020.20139","DOIUrl":"https://doi.org/10.5152/tjg.2020.20139","url":null,"abstract":"<p><strong>Background/aims: </strong>The importance of identifying the stage of liver fibrosis has motivated the development of non-invasive methods. This study aimed to evaluate the applicability of ultrasound analysis involving the wave-number domain attenuation coefficient (W-Ac) in the non-invasive quantitative differentiation of liver fibrosis.</p><p><strong>Materials and methods: </strong>This was a prospective study of inpatients with hepatitis B-related liver disease treated between October 2016 and January 2018. In ultrasound, the echo from the near-field liver tissue was selected as the reference signal. The W-Ac of liver tissues was based on the fast Fourier transform of the acquired post-beamforming radio frequency signals. These values were compared with fibrosis from biopsy METAVIR score results. A receiver operating characteristic (ROC) curve tested the W-Ac method.</p><p><strong>Results: </strong>A total of 46 patients were enrolled, including 27 males and 19 females. Fibrosis was stage F0 in 12 patients, F1 in 13 patients, F2 in 10 patients, F3 in 7 patients, and F4 in 4 patients. W-Ac increased with the progression of liver fibrosis up to stage F3. There were differences between F0 and F4 stages (p<0.001) and between any 2 stages of fibrosis (p<0.05), except for stages F3 and F4. There was a significant correlation between W-Ac and METAVIR score (r=0.795, p<0.001). W-Ac differed between non-fibrosis (F0) and fibrosis (F1-F4) groups (p<0.001) and in the normal (F0), early fibrosis (F1-2), and late fibrosis groups (F3-4) (p<0.001). ROC area under the curve was 0.890, and at a cut-off of 0.12153, sensitivity was 0.706 and specificity was 0.830.</p><p><strong>Conclusions: </strong>W-Ac allowed assessment of liver fibrosis in clinical practice.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"923-929"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928246/pdf/tjg-31-12-923.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Larynx-preserving limited resection with total thoracic esophagectomy and gastric pull-up reconstruction: A promising treatment for selected cervical esophageal squamous cell carcinoma.","authors":"Wu-Ping Wang,&nbsp;Jie Ma,&nbsp;Qiang Lu,&nbsp;Yong Han,&nbsp;Xiao-Fei Li,&nbsp;Tao Jiang,&nbsp;Jin-Bo Zhao","doi":"10.5152/tjg.2020.19757","DOIUrl":"https://doi.org/10.5152/tjg.2020.19757","url":null,"abstract":"<p><strong>Background/aims: </strong>There is no consensus on treatment for cervical esophageal squamous cell carcinoma (ESCC). Our aim is to evaluate the feasibility and outcome of larynx-preserving limited resection with total thoracic esophagectomy and gastric pull-up reconstruction for the treatment of cervical ESCC without tumor involvement of the larynx and hypopharynx.</p><p><strong>Materials and methods: </strong>Retrospective analysis of patients with cervical ESCC who underwent R0 surgical resection from 2006 to 2011 in our center was performed. Kaplan-Meier method was used to calculate the survival time for patients.</p><p><strong>Results: </strong>In total, 74 cervical ESCC patients were enrolled in the study. The mortality rate in 30 days was 8.1%, the total complication rate (at least one) was 47.3%, anastomosis leakage occurrence was 37.8%, mechanical ventilation ratewas12.2%, the rate of normal oral diet within 15 days was 71.6%, and the anastomosis recurrence rate in follow-up was 8.1%. Detailed analysis showed that the anastomosis leakage, pulmonary infection, laryngeal recurrent nerve injury, and chylothorax were the most common complications in surgical patients. Finally, the survival data showed that the median survival time was 31.83 months (95% CI=12.39-51.28 months) and the 3-year and 5-year survival rates were 49.1% and 35.5%, respectively.</p><p><strong>Conclusion: </strong>Larynx-preserving limited resection with total thoracic esophagectomy and gastric pull-up reconstruction might be a feasible and effective surgical alternative for the cervical ESCC patients whose tumor does not involve the larynx and hypopharynx.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"948-954"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928245/pdf/tjg-31-12-948.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A very uncommon clinical entity: Lansoprazole-induced symptomatic hyponatremia in a young woman.","authors":"Mustafa Kaplan,&nbsp;Alpaslan Tanoğlu,&nbsp;Tolga Düzenli,&nbsp;Başak Çakır Güney,&nbsp;Yeşim Önal Taştan","doi":"10.5152/tjg.2020.19374","DOIUrl":"https://doi.org/10.5152/tjg.2020.19374","url":null,"abstract":"A 31-year-old female patient was admitted to the emergency room with nausea, weakness, and headache. Her medical history revealed sudden cardiac arrest because of Prolonged QT syndrome, followed by cardioversion 6 months ago. Coronary angiography imagery was normal but an operation was performed to insert an implantable cardioverter-defibrillator to correct abnormal heart rhythm. One week ago she was admitted to the cardiology clinic with chest pain, and acute pericarditis was diagnosed. Ibuprofen 200 mg tablet b.i.d., colchium dispert 0.5 mg tablets t.i.d., and lansoprozole 30 mg capsule b.i.d. were prescribed. Her family history was positive for sudden cardiac arrest because of Prolonged QT syndrome. She denied ever drinking alcohol, smoking, or using any kind of herbal or folk remedies. Her physical examination revealed decreased heart sounds in auscultation. Abdominal and neurologic examinations were normal. Serum sodium concentration was 115 mmol/L (135-145 mmol/L), potassium was 4.9 mmol/L (3.5-5.5 mmol/L), serum creatinine was 0.63 mg/dL (0.4-1.2 mg/dL), and chloride was 90 mmol/L (97-107 mmol/L). Blood urea nitrogen concentration and liver function tests were within the normal range. A cardiologist had reviewed her in the emergency room, and just a little cardiac effusion was noticed with echocardiogram; no other emergency cardiac pathology was diagnosed. Her abdominal ultrasonographic examination also revealed no pathology. The patient was then hospitalized.","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"957-959"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928252/pdf/tjg-31-12-957.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Berberine inhibits liver damage in rats with non-alcoholic fatty liver disease by regulating TLR4/MyD88/NF-κB pathway.","authors":"Lingling Wang,&nbsp;Zhandong Jia,&nbsp;Bangcai Wang,&nbsp;Bin Zhang","doi":"10.5152/tjg.2020.19568","DOIUrl":"https://doi.org/10.5152/tjg.2020.19568","url":null,"abstract":"<p><strong>Background/aims: </strong>This study aimed to explore the therapeutic effects and underlying mechanism of berberine (BBR) on the non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet (HFD).</p><p><strong>Materials and methods: </strong>Rats were randomly divided into the following 4 groups: control (normal diet), model (HFD), polyene phosphatidylcholine HFD+PPC, and BBR (HFD+BBR) group. The NAFLD models were prepared by feeding with HFD for 12 weeks. The liver tissues were observed by oil red O staining. H-E staining was used to detect pathological changes in the liver tissues. Serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were detected by an automatic biochemical analyzer. ELISA was performed to observe the inflammatory cytokines (TNF-α, IL-6, and IL-1β) expressions. The levels of TLR4, MyD88, and NF-κB p65 were analyzed using western blot and qRT-PCR, respectively. The nuclear translocation levels of NF-κB in the primary liver cells were measured using flow cytometry.</p><p><strong>Results: </strong>BBR could significantly alleviate the liver tissue steatosis and inflammatory cell infiltration; reduce the NAFLD activity scores and serum levels of ALT, AST, TC, and LDL-C; decrease the levels of TNF-α, IL-6, and IL-1β, and reduce the expression of TLR4, MyD88, and NF-κB in the liver tissues. BBR could also reverse the nuclear translocation of NF-κB in the primary liver cells.</p><p><strong>Conclusion: </strong>BBR alleviated the progress of NAFLD and liver damage, which might contribute to inhibit the nuclear translocation of NF-κB via the TLR4/MyD88/NF-κB pathway.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"902-909"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928262/pdf/tjg-31-12-902.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short chain fatty acids and monocarboxylate transporters in irritable bowel syndrome.","authors":"Ernst Fredericks,&nbsp;Reza Theunissen,&nbsp;Saartjie Roux","doi":"10.5152/tjg.2020.19856","DOIUrl":"https://doi.org/10.5152/tjg.2020.19856","url":null,"abstract":"<p><strong>Background/aims: </strong>Gut microbiota ferments indigestible food that rests in the colon to produce short-chain fatty acids (SCFAs) acetate, propionate, and butyrate. Colonic SCFA stimulate the synthesis of serotonin which is central in irritable bowel syndrome (IBS) pathophysiology. Reduced SCFA have been linked to specific IBS symptoms like colonic hyperalgesia and hypersensitivity. SCFA enter the colonocyte mainly via 2 energy-dependent monocarboxylate transporters, MCT1 (SLC16A1) and SMCT1 (SLC5A8). We investigated specific gut microbiota, SCFA concentrations, and monocarboxylate transporter mRNA expression in patients with IBS.</p><p><strong>Material and methods: </strong>A total of 30 IBS patients-15 constipation-predominant (C-IBS) and 15 diarrhoea-predominant (D-IBS)-and 15 healthy controls were recruited. Bacteroidetes and Bifidobacterium species were analyzed using quantitative polymerase chain reaction (qPCR) on stool samples. SCFA concentrations were determined by gas chromatography/mass spectroscopy of stool samples. Monocarboxylate transporter mRNA was quantified by qPCR on colon biopsy specimens.</p><p><strong>Results: </strong>Bacteroides was significantly increased in the D-IBS group compared with the C-IBS group and healthy controls. Bifidobacterium was significantly reduced in both IBS groups. SCFA ratios were altered in both IBS groups with a reduction of all 3 measured SCFA in C-IBS and acetic acid in D-IBS. MCT1 and SMCT1 were significantly reduced in C-IBS and D-IBS.</p><p><strong>Conclusion: </strong>In agreement with findings of previous studies, the microbiota assessed were significantly altered inferring dysbiosis in IBS. SCFA and their ratios were significantly altered in both IBS groups. SCFA transporters, MCT1 and SMCT1 were significantly reduced in both IBS groups, suggesting reduced colonocyte SCFA transfer. SCFA availability and transfer into the colonocytes may be important in IBS pathogenesis and should be prospectively studied.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"840-847"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928259/pdf/tjg-31-12-840.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25406841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eradication of Helicobacter Pylori Infections and GERD: A systematic review and meta-analysis.","authors":"Wen-Ling Mou,&nbsp;Meng-Yao Feng,&nbsp;Li-Hua Hu","doi":"10.5152/tjg.2020.19699","DOIUrl":"https://doi.org/10.5152/tjg.2020.19699","url":null,"abstract":"<p><strong>Background/aims: </strong>This study evaluates the association between the eradication of Helicobacter pylori (H. pylori) and gastroesophageal reflux disease (GERD).</p><p><strong>Materials and methods: </strong>Relevant studies were identified by conducting literature search in PubMed, Cochrane, Embase, CNKI, VANFUN, and VIP databases. The prevalence rates of gastroesophageal reflux, heartburn, epigastric pain, and nausea were extracted from the identified research articles and were used in meta-analysis of relative risks (RR) to achieve an overall effect size of the relationship between H. pylori eradication and GERD.</p><p><strong>Results: </strong>A total of 19 randomized controlled trials were included in this meta-analysis. The prevalence of gastroesophageal reflux was significantly higher in patients with H. pylori eradication compared with patients without it (RR: 1.54, 95% CI: 1.06-2.24; p=0.02). A subgroup analysis did not identify any significant difference in GERD prevalence in studies conducted outside China (RR: 1.62, 95% CI: 0.98-2.68) or in China (RR: 1.30, 95% CI: 0.76-2.22). There were no significant differences in heartburn (RR: 1.03, 95% CI: 0.88-1.20), epigastric pain (RR: 0.98, 95% CI: 0.13-7.56), or nausea (RR: 0.44, 95% CI: 0.07-2.72) risk between patients with and without H. pylori eradication.</p><p><strong>Conclusion: </strong>Eradication of H. pylori infection is found to be associated with GERD, although regional differences may exist in the prevalence. Well-designed studies especially those with stratification of patients' basic conditions are needed to seek refined evidence of the association between H. pylori eradication and the GERD.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"853-859"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928256/pdf/tjg-31-12-853.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25406843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided percutaneous venting duodenostomy: New technique.","authors":"Iyad Khamaysi,&nbsp;Maxim Leiderman,&nbsp;Eisa Hajj,&nbsp;Kamel Yassin","doi":"10.5152/tjg.2020.2001","DOIUrl":"https://doi.org/10.5152/tjg.2020.2001","url":null,"abstract":"","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"962-963"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928251/pdf/tjg-31-12-962.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two decades of research on autoimmune liver disease in Turkey.","authors":"Nurhan Demir,&nbsp;Nazım Ekin,&nbsp;Murat Torgutalp,&nbsp;Staffan Wahlin,&nbsp;Cumali Efe","doi":"10.5152/tjg.2020.19866","DOIUrl":"https://doi.org/10.5152/tjg.2020.19866","url":null,"abstract":"<p><strong>Background/aims: </strong>Autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) are the 3 main autoimmune liver diseases (AILDs). The epidemiology of AILD in Turkey is not known. To determine the scientific status, we performed a scientometric analysis of AILD-related original articles that originated from Turkey.</p><p><strong>Materials and methods: </strong>We searched the Web of Science database, the Science Citation Index Expanded (SCI-E), and the Social Sciences Citation Index (SSCI) by using the keywords \"autoimmune hepatitis,\" \"primary biliary cholangitis/primary biliary cirrhosis,\" and \"primary sclerosing cholangitis\" in conjunction with \"Turkey.\" A scientometric analysis was done on the search results.</p><p><strong>Results: </strong>We identified 117 AILD-related papers that were published in Turkey from 1997 to 2019. Among these, 70 case reports, letters, and reviews and 2 original articles that were not cited in SCI-E/SSCI were excluded. The remaining 45 original articles were further analyzed. These studies were related to AIH (n=22), PBC (n=7), PSC (n=9), PBC-AIH overlap (n=5), and others (n=2). Four of the publications originated in pediatric settings; 9 of 45 papers were published from 1997 to 2008 and 36 papers were published from 2009 to 2019. Most papers (75%) were reported from 5 centers; 9 papers (20%) were published in journals with an impact factor of 3 or higher.</p><p><strong>Conclusion: </strong>The overall number and quality of AILD-related papers in Turkey are unexpectedly low, although a number of papers have received considerable international recognition. More epidemiologic, prospective, and multicenter research projects are warranted to advance AILD knowledge and to produce high-quality research from Turkey.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"877-882"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928254/pdf/tjg-31-12-877.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25406846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of lncRNA MSC-AS1 in hepatocellular carcinoma cell lines and its effect on proliferation, apoptosis, and migration.","authors":"Xiaoni Kou,&nbsp;Jiang Zhu,&nbsp;Xinke Xie,&nbsp;Mingxia Hao,&nbsp;Yingren Zhao","doi":"10.5152/tjg.2020.19485","DOIUrl":"https://doi.org/10.5152/tjg.2020.19485","url":null,"abstract":"<p><strong>Background/aims: </strong>This study aimed to explore the expression of long non-coding RNA MSC-AS1 in hepatocellular carcinoma (HCC) cells and its effect on the proliferation, migration, and apoptosis of HCC cells.</p><p><strong>Materials and methods: </strong>The expression of MSC-AS1 in HCC cell lines BEL7402, SMMC7721, Huh7, HepG2, MHCC97-H, and normal hepatocyte line L02 was detected by reverse transcriptase polymerase chain reaction. The HCC cells were divided into blank, negative control (NC)-small interfering RNA (siRNA) (transfected with negative siRNA), and MSC-AS1 siRNA (transfected with MSC-AS1 siRNA) groups. Cell counting kit-8 and colony formation assays were used to determine the proliferation, and cell apoptosis, migration, and invasion were detected by flow cytometry, wound healing, and transwell assays, respectively. Western blot was used to detect the expression of related proteins.</p><p><strong>Results: </strong>The expression of MSC-AS1 in HCC cell lines was significantly higher than that in L02. In the MSC-AS1 siRNA group, the proliferation and colony formation of HCC cells were inhibited, whereas the apoptosis rate was significantly higher than that in the blank and NC-siRNA groups. The rate of wound healing and the number of invasion cells in the MSC-AS1 siRNA group were significantly lower than that in the blank and NC-siRNA groups.</p><p><strong>Conclusion: </strong>MSC-AS1 was upregulated in HCC cells, and the downregulation of MSC-AS1 could inhibit cell proliferation, migration, and invasion and promote apoptosis of HCC cells.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"860-867"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928261/pdf/tjg-31-12-860.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25406844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary extrasensal nasal-type natural killer/T-cell lymphoma of the sigmoid colon and ıleocecal junction: A case report.","authors":"Chang Gao,&nbsp;Jia-Long Liu,&nbsp;Meng-Na Zhang,&nbsp;Pei-Shan Qiu,&nbsp;Xi-Xian Zhao,&nbsp;Qiu Zhao,&nbsp;Jing Liu,&nbsp;Xian-Yan Shi","doi":"10.5152/tjg.2020.19873","DOIUrl":"https://doi.org/10.5152/tjg.2020.19873","url":null,"abstract":"Extranodal natural killer/T-cell lymphoma (ENKTL) involving the intestinal tract is a rare disease. A total of 191 cases of ENKTL involving the gastrointestinal (GI) tract have been reported in the world literature, with a maximum age of onset of 79 years. Among them, 5 cases were involved in the sigmoid colon. Here, we reported the case of an 82-year-old ENKTL patient with sigmoid colon and ileocecal junction involvement, who had achieved a partial response after treatment with chidamide and prednisone.","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"955-956"},"PeriodicalIF":1.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928242/pdf/tjg-31-12-955.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}