GE Portuguese Journal of Gastroenterology最新文献

{"title":"Erratum.","authors":"","doi":"10.1159/000528365","DOIUrl":"https://doi.org/10.1159/000528365","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1159/000526125.].</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"173"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/d9/pjg-0030-0173.PMC10050853.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000528334","DOIUrl":"https://doi.org/10.1159/000528334","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1159/000524062.].</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"170"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ab/3a/pjg-0030-0170.PMC10050846.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000528332","DOIUrl":"https://doi.org/10.1159/000528332","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1159/000523773.].</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"170"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/e1/pjg-0030-0170.PMC10050854.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Intestinal Failure and Home Parenteral Support: A Single Center Experience.","authors":"Mariana Brito,&nbsp;Mafalda Padinha,&nbsp;Sandra Carlos,&nbsp;Cátia Oliveira,&nbsp;Ana Paula Santos,&nbsp;Gonçalo Nunes,&nbsp;Carla Adriana Santos,&nbsp;Jorge Fonseca","doi":"10.1159/000522161","DOIUrl":"https://doi.org/10.1159/000522161","url":null,"abstract":"<p><strong>Introduction: </strong>Home parenteral nutrition (HPN) and/or home parenteral hydration (HPH) are the gold-standard treatment for patients with long-term intestinal failure (IF). The authors aimed to assess the impact of HPN/HPH on nutritional status and survival of long-term IF patients, as well as HPN/HPH-related complications.</p><p><strong>Methods: </strong>This was a retrospective study including IF patients under HPN/HPH followed in a single large tertiary Portuguese hospital. The data collected included demographics, underlying conditions, anatomical characteristics, type and duration of parenteral support, IF functional, pathophysiological, and clinical classifications, body mass index (BMI) at the beginning and end of follow-up, complications/hospitalizations, current patient status (deceased, alive with HPN/HPH, and alive without HPN/HPH), and cause of death. Survival after HPN/HPH beginning, until death or August 2021, was recorded in months.</p><p><strong>Results: </strong>Overall 13 patients were included (53.9% female, mean age 63.46 years), and 84.6% of patients presented type III IF and 15.4% type II. Short bowel syndrome caused 76.9% of IF. Nine patients received HPN and 4 HPH. Eight patients (61.5%) were underweight at the beginning of HPN/HPH. At the end of follow-up, 4 patients were alive without HPN/HPH, 4 maintained HPN/HPH, and 5 died. All patients improved their BMI (mean initial BMI 18.9 vs. 23.5 at the end, <i>p</i> < 0.001). Eight patients (61.5%) were hospitalized due to catheter-related complications, mainly infectious (mean hospitalization episodes 2.25, mean hospital stay of 24.5 days). No deaths were related to HPN/HPH.</p><p><strong>Conclusion: </strong>HPN/HPH significantly improved IF patients' BMI. HPN/HPH-related hospitalizations were common, however causing no deaths, reinforcing that HPN/HPH is an adequate and safe therapy for long-term IF patients.</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"127-133"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b6/66/pjg-0030-0127.PMC10050871.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9241845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solitary Peutz-Jeghers Type Hamartomatous Polyp Arising from the Appendix.","authors":"Mariana Sant'Anna,&nbsp;Elisa Gravito-Soares,&nbsp;Marta Gravito-Soares,&nbsp;Sofia Mendes,&nbsp;Pedro Narra Figueiredo","doi":"10.1159/000521196","DOIUrl":"https://doi.org/10.1159/000521196","url":null,"abstract":"Digestive hamartomatous polyps may be solitary or multiple, the latter often associated with genetic predisposition [1, 2]. Solitary Peutz-Jeghers (PJ)-type hamartomatous polyps represent a rare and distinct entity from the classic PJ syndrome, an autosomal dominant genetic disorder characterized by the development of multiple polyps in the gastrointestinal (GI) tract in association with patches of hyperpigmentation in the mouth, hands and feet [1, 3]. It is important to distinguish these two entities since the latter is associated with a lifetime cumulative risk of up to 93% for development of malignancies (such as colorectal, breast, small bowel, gastric and pancreatic cancers), but the first seems benign in its course. Solitary PJ polyps are diagnosed in patients with an isolated hamartomatous polyp of the GI tract, no familiar history of polyposis and no typical phenotype [3]. An 80-year-old man with a history of sigmoidectomy due to an obstructive T2N0M0 colorectal cancer underwent a surveillance thoracoabdominopelvic CT scan showing a voluminous endoluminal polyp at the caecum (Fig. 1). He was referred to our reference centre for colonoscopy. A 4-cm diameter pedunculated and congestive polyp was identified with a short and thick stalk arising from the appendiceal orifice. We proceeded to its en bloc resection using a 25-mm oval diathermic snare after stalk injection with diluted adrenaline 1:10,000, normal saline and methylene blue with polyp recovery for histology (Fig. 2a–c, 3a). The polyp was confirmed to be a hamartomatous polyp of the PJ type (R0 resection) with arborizing pattern of vascularized smooth-muscle tissue axes covered by elongated veliform crypts and occasional intraluminal necrosis with no dysplasia (Fig. 3b). The patient had no typical manifestations of PJ syndrome or family history. His follow-up showed no complications related to the procedure, including bleeding or acute appendicitis (prophylactic antibiotic was not used). Solitary PJ-type hamartomatous polyps of the GI tract are rare, and appendiceal location is even rarer. Accord-","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"156-158"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/72/pjg-0030-0156.PMC10050839.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9241699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small Bowel Adenocarcinoma in a Patient with Crohn's Disease: The Role of Balloon-Assisted Enteroscopy.","authors":"Emanuel Dias,&nbsp;Miguel Mascarenhas Saraiva,&nbsp;Francisco Moreira,&nbsp;Hélder Cardoso,&nbsp;Guilherme Macedo","doi":"10.1159/000520906","DOIUrl":"https://doi.org/10.1159/000520906","url":null,"abstract":"<p><strong>Introduction: </strong>Small bowel adenocarcinoma is a rare but well-known complication of Crohn's disease. Diagnosis can be challenging, as clinical presentation may mimic an exacerbation of Crohn's disease and imaging findings may be indistinguishable from benign strictures. The result is that the majority of cases are diagnosed at the time of operation or postoperatively at an advanced stage.</p><p><strong>Case presentation: </strong>A 48-year-old male with a previous 20-year history of ileal stenosing Crohn's disease presented with iron deficiency anemia. The patient reported melena approximately 1 month earlier but was currently asymptomatic. There were no other laboratory abnormalities. Anemia was refractory to intravenous iron replacement. The patient underwent computerized tomography enterography, which revealed multiple ileal strictures with features suggesting underlying inflammation and an area of sacculation with circumferential thickening of adjacent bowel loops. Therefore, the patient underwent retrograde balloon-assisted small bowel enteroscopy, where an area of irregular mucosa and ulceration was found at the region of ileo-ileal anastomosis. Biopsies were performed and histopathological examination revealed tubular adenocarcinoma infiltrating the muscularis mucosae. The patient underwent right hemicolectomy plus segmental enterectomy of the anastomotic region where the neoplasia was located. After 2 months, he is asymptomatic and there is no evidence of recurrence.</p><p><strong>Discussion: </strong>This case demonstrates that small bowel adenocarcinoma may have a subtle clinical presentation and that computed tomography enterography may not be accurate enough to distinguish benign from malignant strictures. Clinicians must, therefore, maintain a high index of suspicion for this complication in patients with long-standing small bowel Crohn's disease. In this setting, balloon-assisted enteroscopy may be a useful tool when there is raised concern for malignancy, and it is expected that its more widespread use could contribute to an earlier diagnosis of this severe complication.</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"141-146"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/a9/pjg-0030-0141.PMC10050865.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9241700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Submucosal Dissection for Subepithelial Tumor Treatment in the Upper Digestive Tract: A Western, Multicenter Study.","authors":"Raffaele Manta,&nbsp;Francesco Paolo Zito,&nbsp;Francesco Pugliese,&nbsp;Angelo Caruso,&nbsp;Santi Mangiafico,&nbsp;Alessandra D'Alessandro,&nbsp;Danilo Castellani,&nbsp;Ugo Germani,&nbsp;Massimiliano Mutignani,&nbsp;Rita Luisa Conigliaro,&nbsp;Luca Reggiani Bonetti,&nbsp;Takahisa Matsuda,&nbsp;Vincenzo De Francesco,&nbsp;Angelo Zullo,&nbsp;Giuseppe Galloro","doi":"10.1159/000525993","DOIUrl":"https://doi.org/10.1159/000525993","url":null,"abstract":"<p><strong>Background/aims: </strong>Endoscopic submucosal dissection (ESD) has been proposed for removal of gastrointestinal subepithelial tumors (GI-SETs), but data are still scanty. This study aimed to report a case series from a western country.</p><p><strong>Patients and methods: </strong>Data of patients with upper GI-SETs suitable for ESD removal observed in 4 centers were retrospectively reviewed. Before endoscopic procedure, the lesion was characterized by endosonographic evaluation, histology, and CT scan. The <i>en bloc</i> resection and the R0 resection rates were calculated, as well as incidence of complications, and the 1-year follow-up was reported.</p><p><strong>Results: </strong>Data of 84 patients with esophageal (<i>N</i> = 13), gastric (<i>N</i> = 61), and duodenal (<i>N</i> = 10) GI-SETs were collected. The mean diameter of lesions was 26 mm (range: 12-110 mm). There were 17 gastrointestinal stromal tumors, 12 neuroendocrine tumors, 35 leiomyomas, 18 lipomas, and 2 hamartomas. <i>En bloc</i> and R0 resection were achieved in 83 (98.8%) and in 80 (95.2%) patients, respectively. Overall, a complication occurred in 11 (13.1%) patients, including bleeding (<i>N</i> = 7) and perforation (<i>N</i> = 4). Endoscopic approach was successful in all bleedings, but 1 patient who required radiological embolization, and in 2 perforations, while surgery was performed in the other patients. Overall, a surgical approach was eventually needed in 5 (5.9%), including 3 in whom R0 resection failed and 2 with perforation.</p><p><strong>Conclusions: </strong>Our study found that ESD may be an effective and safe alternative to surgical intervention for both benign and localized malignant GI-SETs.</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"115-120"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a0/3e/pjg-0030-0115.PMC10050838.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9241702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000528361","DOIUrl":"https://doi.org/10.1159/000528361","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1159/000525994.].</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"172"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/9a/pjg-0030-0172.PMC10050868.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000528333","DOIUrl":"https://doi.org/10.1159/000528333","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1159/000524060.].</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"170"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/7e/pjg-0030-0170.PMC10050831.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000528359","DOIUrl":"https://doi.org/10.1159/000528359","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1159/000525993.].</p>","PeriodicalId":51838,"journal":{"name":"GE Portuguese Journal of Gastroenterology","volume":"30 2","pages":"172"},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8e/d1/pjg-0030-0172.PMC10050862.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9597035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}