{"title":"NON – IgE – MEDIATED GASTROINTESTINAL FOOD ALLERGY IN CHILDREN","authors":"M. Živanović, Marina Atanaskovic-Markovic","doi":"10.46793/pp240130003z","DOIUrl":"https://doi.org/10.46793/pp240130003z","url":null,"abstract":"Nutrition allergy is unfavorable immune response to food proteins. Non-IgE-mediated gastrointestinal food allergy includes spectrum of disorders which are more uncommon that IgE- mediated food allergies. Their diagnosis is mainly done by clinical features cause the absence of specific biomarkers. Non-IgE-mediated food allergies include: food protein-induced enterocolitis sydrome (FPIES), food-protein induced allergic proctocolitis (FPIAP), food-protein induced allergic enteropathy (FPE), food protein induced dysmotility disorders (GERD) and mixed type diseases for examp. Eosinophilic esophagitis (EoE). In most cases non-IgE-mediated food allergy have a good prognosis and resolving during childhood.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140388003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PRAVOVREMENOST VAKCINACIJE PREVREMENO ROĐENE DECE","authors":"Tanja Rožek Mitrović","doi":"10.46793/pp231202009r","DOIUrl":"https://doi.org/10.46793/pp231202009r","url":null,"abstract":"Prevremeno rođena deca su značajna populacija sa aspekta javnog zdravlja, morbiditeta i mortaliteta te je preventivni rad i vakcinacija od velikog značaja. Prevremeno rođena deca imaju veći rizik za pojavu neonatalnih i infektivnih bolesti, zbog nezrelosti imunog sistema i slabog prenosa zaštitnih majčinih antitela. Mnoge infektivne bolesti mogu se sprečiti sprovođenjem vakcinacije. Međutim, najveći problem u zemlji i inostranstvu je neblagovremena i nepotpuna vakcinacija prevremeno rođene dece. Pregledom literaturnih podataka u ovom radu predstavljeni su načini i protokoli sprovođenja pravovremenosti vakcinacije prevremeno rođene dece, sa ciljem efikasne prevencije zaraznih bolesti.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140387918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AN OVERVIEW OF CURRENT VACCCINES FOR THE PROPHYLAXIS OF BACTERICAL INFECTIONS","authors":"Dragana D. Božić, Biljana Bufan","doi":"10.46793/pp240214004b","DOIUrl":"https://doi.org/10.46793/pp240214004b","url":null,"abstract":"Antibacterial vaccines play a central role in modern medicine by providing an effective approach to combating infectious diseases caused by bacteria. The importance of these vaccines lies in their ability to stimulate the immune system to recognise and neutralise bacterial pathogens, or exotoxins produced by them, thereby preventing, or mitigating the severity of bacterial infections. The development and widespread use of antibacterial vaccines have contributed significantly to reducing the global burden of diseases such as pneumonia, meningitis, and sepsis.\u0000Today, the global increase in vaccine-preventable diseases is a worrying trend that is closely linked to the emergence and advocacy of anti-vaccination policies. According to the latest World Health Organisation report, vaccination coverage in Serbia has declined over the past decade, jeopardising the collective immunity and led to recent outbreaks of vaccine-preventable diseases such as whooping cough and measles. Understanding the significance of antibacterial vaccines underscores their importance in promoting individual and community immunity, which ultimately leads to a healthier population and the prevention of antibiotic resistance.\u0000This paper summarises the main characteristics of the different types of antibacterial vaccines, such as whole cell vaccines, subunit vaccines and toxoid vaccines, and provides an overview of the types of bacterial antigens contained in vaccines available for mandatory immunisation (vaccines against tuberculosis, diphtheria, tetanus, pertussis, Haemophilus influenzae and pneumoccus) or for non-mandatory immunisation (meningococcal vaccine, typhoid vaccine, cholera vaccine).","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140387924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PROBIOTICS FOR THE PREVENTION OF VENTILATOR-ASSOCIATED PNEUMONIA","authors":"Natia Chkhaidze, Maia Kherkheulidze, Ivane Chkhaidze","doi":"10.46793/pp231110006c","DOIUrl":"https://doi.org/10.46793/pp231110006c","url":null,"abstract":"Ventilator-associated pneumonia is associated with a high rate of all-cause mortality and a prolonged duration of mechanical ventilation and intensive care unit stay. Ventilator associated pneumonia accounts for about half of all antibiotics given in the intensive care unit. Plenty of studies have assessed various kinds of prevention strategies, including pharmacological and non-pharmacological interventions, to prevent ventilator-associated pneumonia over the years. An emerging number of studies has assessed the non-antibiotic approaches for the prevention of ventilator-associated pneumonia in the last few years. One of the frequently used strategy is addition of probiotics in the preventive measures list. Regular consumption of probiotics can modulate immune responses and metabolic processes as well as antioxidant and anti-inflammatory effects. The strongest evidence in favor of probiotics lies in the prevention or treatment of necrotizing enterocolitis, acute infectious diarrhea, acute respiratory tract infections, antibiotic-associated diarrhea, and infant colic. The beneficial effects of probiotics in the prevention of ventilator-associated pneumonia were not yet entirely clarified. Multiple pieces of evidence indicate that the bacteria that populate the gut efficiently modulate the immune response. Treatment with probiotics have shown promising preliminary results to attenuate systemic inflammation, especially in postoperative infections and ventilation performance. This review aims to summarize latest data on the use probiotics to prevent ventilator-associated pneumonia in critical care unit.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140388059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OLIGOARTIKULARNI JUVENILNI IDIOPATSKI ARTRITIS: PRAVOVREMENA DIJAGNOZA I TERAPIJA U CILJU PREVENCIJE HRONIČNIH OŠTEĆENJA ZGLOBOVA","authors":"Dragan Lazarević, Maja Zečević","doi":"10.46793/pp240127010l","DOIUrl":"https://doi.org/10.46793/pp240127010l","url":null,"abstract":"Oligoartikularni podtip juvenilnog idiopatskog artritisa (JIA) klinički definiše prisustvo artritisa u manje od pet zglobova tokom prvih šest meseci trajanja bolesti. Ako pojava artritisa ostane lokalizovana na manje od pet zglobova tokom celog perioda trajanja bolesti, onda govorimo o trajnom (perzistentnom) oligoartritisu. Ukoliko se u toku 6 meseci od pojave prvih zglobnih tegoba artritis proširi na 5 i više zglobova onda govorimo o esktendiranoj, proširenoj formi oligoartritisa, koji tokom vremena ima isti tok bolesti kao RF negativni poliartritis. Poslednjih decenija nova saznanja o etiopatogenezi JIA i napredak genetskog inženjeringa su omogućili razvoj i primenu novih terapijskih algoritama kod obolelih od JIA što je svakako promenilo tok, prognozu i ishod bolesti kod ovih pacijenata. Savremeni koncept lečenja ima za cilj da obezbedi dobar kvalitet života ovim pacijentima, da se aktivnost bolesti dovede pod kontrolu, da umanji subjektivne tegobe, omogući normalan rast i razvoj dece, očuva funkcionalnost zglobova i prevenira pojavu deformiteta, nastanak invalidnosti i radne nesposobnosti. Savremeni koncept lečenja JIA teži indivudualizaciji terapijskog pristupa svakom bolesniku. U poređenju sa ostalim podtipovima JIA, oligoartikularna forma ima najbolju prognozu, posebno ukoliko govorimo o perzistentnom podtipu oligoartritisa.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140388124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DETECTION OF MEDICAL NEGLECT AND PREVENTION","authors":"Mira Stjepanović","doi":"10.46793/pp240227020s","DOIUrl":"https://doi.org/10.46793/pp240227020s","url":null,"abstract":"Neglect is defined as the chronic failure of parents (guardians) to provide the child with the basic conditions necessary for its growth and development: food, clothing, housing, medical care and protection, encouraging the child's development. Diagnosing neglect requires teamwork, knowledge of symptoms and signs, as well as family characteristics. Types of neglect: physical, emotional, educational, lack of medical care. In case of suspected neglect, the competent professional team should be notified. The goal is early prevention and early intervention in case of neglect.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140388099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"HEALTH STATUS AND HEALTH PRACTICES OF MONTENEGRIN FAMILY PHYSCIANS","authors":"Milena Cojic, Aleksandra Klisić","doi":"10.46793/pp230615015c","DOIUrl":"https://doi.org/10.46793/pp230615015c","url":null,"abstract":"Introduction: Physicians have lower mortality rates than general population, but similar rates of chronic diseases.\u0000Aim: The aim was to investigate health status and heath practices of family medicine doctors in Primary Health Care Center Podgorica, Montenegro and compare it to high school teachers.\u0000Method: A total of 104 (69.3%) physicians and 40 teachers (50%) responded to a questionnaire about their health status and health practices.\u0000Results: A total of 45% of practitioners and 45% of teachers self-reported at least one disease without significant difference in the incidence and type of disease (p=0.162). There was also no difference in using sick leave (p=0.633). Both groups tended to work when sick, but significantly more physicians worked when tired (p=0.026). Most of respondents were registered with a general practitioner, but only teachers tended to visit their physician when ill (p<0.001). Thirty minutes of daily physical activity was reported by 16.3% of the physicians and 15.0% of the teachers without a significant difference (p=0.915).\u0000Conclusion: Compared to the teachers Montenegrin physicians have similar health status and health practices. However, physicians more often tend to work when they are tired and to selfcare when they are ill. Physicians need to pay attention to the lifestayle habits and to follow the recommendations for themselves what they provide to their patients.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 91","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140283649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"INTERNET KAO IZVOR INFORMACIJA RODITELJIMA DECE SA SMETNJAMA U RAZVOJU I / ILI HRONIČNIM BOLESTIMA","authors":"I. Ćeranić, Srđanka Tomić, S. Slavković","doi":"10.46793/pp231218012c","DOIUrl":"https://doi.org/10.46793/pp231218012c","url":null,"abstract":"Uvod: Istraživanja ističu ulogu interneta kao izuzetno važnog izvora informacija za roditelje dece sa smetnjama u razvoju i/ili sa hroničnim oboljenjima, što proizilazi iz njihove potrebe da pronađu specifične informacije u vezi sa zdravljem/stanjem i razvojem svoje dece.\u0000Cilj rada: Cilj rada jeste utvrditi načine korištenja interneta od strane roditelja u procesu pronalaska informacija koje se tiču detetovog stanja ili zdravlja radi pružanja podrške detetu sa smetnjama u razvoju i/ili hroničnim bolestima.\u0000Metode rada: Onlajn upitnik je popunilo 104 ispitanika starosti od 18-45 godina. Upitnik, dizajniran za potrebe ovog istraživanja, sadrži 35 pitanja organizovanih u pet delova: socio-demografski podaci o ispitanicima; podaci o detetu; podaci o roditeljskim stavovima prema internet pretraživanju; podaci o roditeljskim stavovima u vezi sa informacijama dobijenih od strane stručnjaka; podaci o društvenom okruženju roditelja.\u0000Rezultati: Utvrđeno je da osnovne informacije koje pretražuju roditelji dece jesu informacije u vezi sa samim procesom rehabilitacije i postupanjem sa detetom. Pokazalo se da stručnjak od kojeg roditelji dobijaju najveći broj informacija jeste lekar. Ono što roditelji najviše cene kod stručnjaka jeste aktivno uključivanje roditelja u proces donošenja odluka u vezi sa detetom. Takođe, iskustva i preporuke ljudi iz okruženja imaju značajan uticaj na roditelje.\u0000Zaključak: Neophodno je promovisati značaj otvorene komunikacije između stručnog lica i roditelja zasnovane na poverenju, informisanost i uključenost roditelja u sve segmente bavljenja detetom.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140387597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OVERVIEW OF THE LIPID ABNORMALITIES IN THE HEART FAILURE","authors":"S. Rafaqat, Sana Rafaqat, Aleksandra Klisić","doi":"10.46793/pp240116008r","DOIUrl":"https://doi.org/10.46793/pp240116008r","url":null,"abstract":"A complicated clinical disease known as heart failure (HF) comes on by anatomical or functional anomalies in the heart that compromise blood flow. This review article presents a comprehensive examination of the role of lipid profiles in the HF. It specifically focuses on the serum levels of traditional lipid parameters, such as total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in the development and progression of the HF. To conduct this review, several databases such as Google Scholar, PubMed, and Science Direct were utilized. Specific keywords used in the search include “heart failure”, “lipid profile”, “triglycerides”, “total cholesterol”, “high-density lipoprotein cholesterol”, and “low-density lipoprotein cholesterol”. The language for clinical investigations included in this review were limited to those set to English. The findings suggest that lower levels of TG may be associated with elevated pulmonary artery pressure, tricuspid regurgitation, and increased dimensions of the right side of the heart. These associations indicate impaired liver function due to right-sided HF in the chronic HF patients. Dysfunctional HDL-C is believed to contribute to the occurrence and advancement of HF. Additionally, serum TC levels have been identified as a potential prognostic factor in individuals with advanced HF. On the other hand, lower LDL-C levels seem to indicate worse prognosis for HF patients. However, further research is required to determine the precise mechanisms by which these lipid profiles influence the development and progression of the HF.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140387916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IMUNIZACIJA PROTIV HUMANOG PAPILOMA VIRUSA NA TERITORIJI GRADA BEOGRADA","authors":"Jasmina Škorić, Marija Klačar Uzelac, Ana Kostić","doi":"10.46793/pp231221013s","DOIUrl":"https://doi.org/10.46793/pp231221013s","url":null,"abstract":"Uvod: Infekcija humanim papiloma virusima je jedna od najčešćih polno prenosivih infekcija.\u0000U cilju prevencije bolesti izazvane HPV virusima u našoj zemlji, od juna 2022. godine, dostupna je devetovalentna HPV vakcina koja se daje kao preporučena vakcina deci od 9 do 19 godina.\u0000Cilj: Ovim radom smo hteli da utvrdimo koliko je dece tj. adolescenata vakcinisano vakcinom protiv HPV virusa, da li među vakcinisanom decom postoji razlika u broju između polova na teritoriji opštine Beograd i koji je procenat dece koji je započeo vakcinaciju, a koji je kompletno vakcinisan na teritoriji opštine Čukarica.\u0000Metod: U radu je kao izvor podataka korišćen periodični izveštaj referenta za imunizaciju Doma zdravlja „Dr Simo Milošević“.\u0000Rezultati: U periodu od juna 2022. godine do novembra 2023. godine, bilo je ukupno 19.839 aplikovanih doza na beogradskim opštinama. Uglavnom, u većini domova zdravlja beležimo ubedljivo veći procenat devojčica koje su započele vakcinaciju, sa izuzetkom DZ Barajevo (50% vakcinisanih dečaka) i DZ Savski venac sa 36% vakcinisanih dečaka.\u0000Zaključak: Za analizirani period od 18 meseci možemo zaključiti da je procenat od 7% koji beležimo na opštini Čukarica poražavajuće nizak. Isto tako 3% dece koja su primila drugu tj. treću dozu je takođe mali, jer u odnosu na 7% vakcinisanih prvom dozom stiče se utisak da skoro polovina nije kompletno vakcinisana.","PeriodicalId":517496,"journal":{"name":"Preventive Paediatrics","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140388236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}