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Antimicrobial Therapy in Dentistry: an Evidence-based Review of Pomegranate Fruit Properties 牙科抗菌疗法：基于证据的石榴果特性综述

Current Dentistry Pub Date : 2024-05-14 DOI: 10.2174/012542579x282756240408073450

Nara Martins Almeida, Laura Catalí Ferreira Peralta, Vanessa Soares Lara

{"title":"Antimicrobial Therapy in Dentistry: an Evidence-based Review of Pomegranate Fruit Properties","authors":"Nara Martins Almeida, Laura Catalí Ferreira Peralta, Vanessa Soares Lara","doi":"10.2174/012542579x282756240408073450","DOIUrl":"https://doi.org/10.2174/012542579x282756240408073450","url":null,"abstract":"\u0000\u0000Phytotherapy is characterized by the use of medicinal plants in their different\u0000dosage forms. Currently, the use of this alternative medicine has increased. The raw material\u0000of herbal medicines consists of organs from medicinal plants (leaves, stems, fruits, peels,\u0000flowers and roots) with pharmacological, food, technical or cosmetic adjuvant effects. In addition,\u0000the side effects of its use appear to be reduced compared to synthetic and conventional medication.\u0000\u0000\u0000\u0000The aim of this mini-review is to present the scientific evidence involving the properties\u0000of the pomegranate fruit for future antimicrobial applications in dentistry.\u0000\u0000\u0000\u0000Literature searches included randomized clinical trials and in vitro studies [2000-2023]\u0000filtered mainly by the following terms [Punica granatum L.], [Pomegranate], [Dentistry], [Antimicrobial\u0000activity] and [Candida albicans].\u0000\u0000\u0000\u0000Studies have shown that Punica granatum Linn. has considerable antimicrobial activity,\u0000in addition to other pharmacological effects such as anti-cancer, antioxidant and antiinflammatory\u0000action. The use of herbal medicines, as potent antimicrobial agents against oral\u0000pathogens, has been widely reported.\u0000\u0000\u0000\u0000The use of P. granatum has proven its effectiveness, as a potent antimicrobial agent\u0000against oral pathogens, especially against the fungus Candida albicans, future studies need to focus\u0000on the development of a biocompatible formulation directed to the treatment of patients with\u0000oral candidiasis.\u0000","PeriodicalId":517337,"journal":{"name":"Current Dentistry","volume":"91 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140978374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalent Oral Drug Delivery System for Dental Care 牙科护理常用口腔给药系统

Current Dentistry Pub Date : 2024-02-02 DOI: 10.2174/012542579x258065231114102420

Amanda Frank, Komal Singh, P. Singh, Neha Bajwa

{"title":"Prevalent Oral Drug Delivery System for Dental Care","authors":"Amanda Frank, Komal Singh, P. Singh, Neha Bajwa","doi":"10.2174/012542579x258065231114102420","DOIUrl":"https://doi.org/10.2174/012542579x258065231114102420","url":null,"abstract":"\u0000\u0000Oral drug delivery systems, including fluoride supplements, constitute one of the most\u0000prevalent routes for the administration of medications, playing a crucial role in the treatment and\u0000prevention of various diseases, including dental caries. Fluorides, employed as a preventive and\u0000control measure against dental caries, are available in two primary forms: systemic fluorides and\u0000topical fluorides. Topical fluorides are found in toothpaste, varnish, gels, mouth rinses, and washes, while systemic fluorides are administered via lozenges, tablets, and liquid formulations.\u0000This literature work focuses on the specific challenges associated with fluoride supplement formulations and aims to shed light on potential setbacks. Among these challenges, poor patient\u0000compliance, especially in pediatric populations, and the associated risk of underdosing or overdosing, leading to fluorosis, stand out as significant concerns. If left unaddressed, these issues\u0000could compromise the efficacy of one of the most effective caries prevention methods available.\u0000The primary objective of this study is to explore advancements in fluoride supplement formulations, with a particular emphasis on addressing the identified challenges, especially for pediatric\u0000and geriatric patients. By devising improved formulations tailored to the unique needs of these\u0000populations, we aim to mitigate compliance issues and minimize the associated risk factors,\u0000thereby strengthening the effectiveness of dental caries prevention strategies. This research endeavors to contribute valuable insights to the field of oral healthcare and pharmaceutical development, ultimately promoting better oral health outcomes for individuals of all ages.\u0000","PeriodicalId":517337,"journal":{"name":"Current Dentistry","volume":"135 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139893633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalent Oral Drug Delivery System for Dental Care 牙科护理常用口腔给药系统

Current Dentistry Pub Date : 2024-02-02 DOI: 10.2174/012542579x258065231114102420

Amanda Frank, Komal Singh, P. Singh, Neha Bajwa

{"title":"Prevalent Oral Drug Delivery System for Dental Care","authors":"Amanda Frank, Komal Singh, P. Singh, Neha Bajwa","doi":"10.2174/012542579x258065231114102420","DOIUrl":"https://doi.org/10.2174/012542579x258065231114102420","url":null,"abstract":"\u0000\u0000Oral drug delivery systems, including fluoride supplements, constitute one of the most\u0000prevalent routes for the administration of medications, playing a crucial role in the treatment and\u0000prevention of various diseases, including dental caries. Fluorides, employed as a preventive and\u0000control measure against dental caries, are available in two primary forms: systemic fluorides and\u0000topical fluorides. Topical fluorides are found in toothpaste, varnish, gels, mouth rinses, and washes, while systemic fluorides are administered via lozenges, tablets, and liquid formulations.\u0000This literature work focuses on the specific challenges associated with fluoride supplement formulations and aims to shed light on potential setbacks. Among these challenges, poor patient\u0000compliance, especially in pediatric populations, and the associated risk of underdosing or overdosing, leading to fluorosis, stand out as significant concerns. If left unaddressed, these issues\u0000could compromise the efficacy of one of the most effective caries prevention methods available.\u0000The primary objective of this study is to explore advancements in fluoride supplement formulations, with a particular emphasis on addressing the identified challenges, especially for pediatric\u0000and geriatric patients. By devising improved formulations tailored to the unique needs of these\u0000populations, we aim to mitigate compliance issues and minimize the associated risk factors,\u0000thereby strengthening the effectiveness of dental caries prevention strategies. This research endeavors to contribute valuable insights to the field of oral healthcare and pharmaceutical development, ultimately promoting better oral health outcomes for individuals of all ages.\u0000","PeriodicalId":517337,"journal":{"name":"Current Dentistry","volume":"164 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139897045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0