The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy最新文献_第2页

Severity of Liver Injury and Its Relation to Clinical Outcome and Duration of Hospitalization in COVID 19 Patients COVID 19 患者肝损伤的严重程度及其与临床结果和住院时间的关系

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-05-16 DOI: 10.24871/251202447-52

Cokorde Istri Yuliandari Krisnawardani Kumbara, I. K. Mariadi, G. Somayana, I. Wibawa, D. A. Sindhughosa

{"title":"Severity of Liver Injury and Its Relation to Clinical Outcome and Duration of Hospitalization in COVID 19 Patients","authors":"Cokorde Istri Yuliandari Krisnawardani Kumbara, I. K. Mariadi, G. Somayana, I. Wibawa, D. A. Sindhughosa","doi":"10.24871/251202447-52","DOIUrl":"https://doi.org/10.24871/251202447-52","url":null,"abstract":"Background: Coronavirus Disease 2019 (COVID-19) can affect not only the respiratory system but also other organs such as the liver. Liver injury tends to occur in severe disease of COVID-19 patients and might contribute to clinical outcomes for patients. This study aimed to find the relationship between the severity of liver injury with clinical outcome and duration of hospitalizations.Methods: This study was a retrospective study of hospitalized COVID-19 patients period April 2020 to April 2021. The inclusion criteria were severe COVID-19 patients who developed a liver injury. The severity of the liver injury was classified into mild, moderate, and severe. The relationship between the severity of liver injury with clinical outcome and duration of hospitalization was analyzed. Univariate and logistic regression were used. Results: 90 samples fill the inclusion criteria. The liver injury severity was statistically significantly related to clinical outcome patients (p= 0.047), which is the increase in liver injury severity resulting in poor clinical outcomes. No significant relationship was found between the severity of liver injury with the duration of hospitalization.Conclusion: liver injury increases mortality in severe COVID-19 patients.","PeriodicalId":515400,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy","volume":"119 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140967603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metastatic Cervical Cancer Presenting as a Sessile Polyp in the Ascending Colon 转移性宫颈癌表现为升结肠无柄息肉

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-05-16 DOI: 10.24871/251202494-97

I. Loho, Lianda Siregar, Dewi Iriani, Tiyas Hasnaa Faatinah

引用次数: 0

Current Management of Non-Alcoholic Fatty Liver Disease (NAFLD) 非酒精性脂肪肝 (NAFLD) 的当前管理方法

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-05-16 DOI: 10.24871/251202463-70

Benny Budiman

引用次数: 0

Tranexamic Acid in the Management of Non-variceal Upper Gastrointestinal Bleeding 氨甲环酸治疗非静脉曲张性上消化道出血

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-05-16 DOI: 10.24871/251202483-93

Muhammad Reza, S. A. Nursyirwan

{"title":"Tranexamic Acid in the Management of Non-variceal Upper Gastrointestinal Bleeding","authors":"Muhammad Reza, S. A. Nursyirwan","doi":"10.24871/251202483-93","DOIUrl":"https://doi.org/10.24871/251202483-93","url":null,"abstract":"Background: Non-variceal upper gastrointestinal bleeding (UGIB) is a common case of emergency in daily clinical practice with a fairly high mortality rate. The use of tranexamic acid, which has been recommended in managing trauma bleeding, may serve as an alternative pharmacological therapy to manage bleeding in non-variceal UGIB. This evidence-based case report aims to evaluate the impact of tranexamic acid on managing bleeding, risk of mortality, and thromboembolic event in non-variceal UGIB patients.Methods: A systematic literature search was conducted on 4 databases: CDSR, EMBASE, PubMed, and Scopus for meta-analyses. Studies were selected based on inclusion and exclusion criteria formulated a-priori with subsequent critical appraisal according to the OCEBM critical appraisal tools. Result: Meta analyses by Kamal, et al (2020) and Twum-Barimah, et al (2020) were included in our report. Kamal, et al shows no significant difference in mortality in tranexamic acid use compared to placebo (RR 0.84; 95%CI 0.63–1.11; I2=2%). Similarly, although Twum-Barimah reported tranexamic acid reduced risk of mortality compared to placebo (RR 0.45; 95%CI 0.23–0.88; p=0.02; I2 = 0%), none of the RCTs included shows significant result when observed individually. In addition, Kamal, et al also reported increased risk of vein thromboembolic events in high-dose tranexamic acid administration (RR 2.21; 95%CI 1.32–3.69; I2=0%) compared to low-dose administration, in UGIB patients.Conclusion: Tranexamic acid is not recommended to be used in managing bleeding in patients non-variceal UGIB patients and may increase the risk of thromboembolic event.","PeriodicalId":515400,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy","volume":"30 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, Attitude and Obstacles of Colorectal Cancer Screening in Primary Health Care in Bali, Indonesia 印度尼西亚巴厘岛基层医疗机构对大肠癌筛查的认识、态度和障碍

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-01-29 DOI: 10.24871/2432023235

I. K. Mariadi, G. Somayana, D. A. Sindhughosa

{"title":"Knowledge, Attitude and Obstacles of Colorectal Cancer Screening in Primary Health Care in Bali, Indonesia","authors":"I. K. Mariadi, G. Somayana, D. A. Sindhughosa","doi":"10.24871/2432023235","DOIUrl":"https://doi.org/10.24871/2432023235","url":null,"abstract":"Background: The knowledge of CRC and its screening methods of healthcare workers is the bedrock of CRC early detection particularly in countries lacking national screening programs. Unknown factors influencing colorectal cancer early detection program implementation. We aimed to evaluate the knowledge and attitudes of primary health care (PHC) provider regarding CRC screening and identify the barriers associated with the screening plan.Methods: A cross-sectional study was conducted among PHC physicians and nurses in public primary health care centers in Bali, Indonesia. A 44-item self-administered questionnaire was used to assess the knowledge, attitude and practice of CRC screening. The questionnaire was spread using google form. Results: Two hundred and five respondents have participated in this study. The average duration of doing practice in PHC is 6.6 years. In knowledge of CRC, 50.2% of them have good knowledge, and there is no difference between PCPs vs nurses (51.9% vs 47.3%; p=0.53). In attitude toward CRC screening, 58.5% out of the have good attitude, and there is no difference between PCPs vs nurses (60.3% vs 55.4%; p=0.50). The barriers of the screening was divided into two areas, a barrier from the health care system and patients. There was no association between knowledge and attitude towards CRC screening (p=0.63).Conclusion: The majority of health workers' knowledge and attitudes toward CRC screening were in the \"good\" category. The patient's fear of being diagnosed with cancer, as well as the patient's fear and anxiety of screening tests, is the most significant barrier to colorectal cancer screening.","PeriodicalId":515400,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140487745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Pancreatitis with Abdominal Bloating and Normal Transabdominal Ultrasound 急性胰腺炎伴腹胀，经腹超声正常

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-01-29 DOI: 10.24871/2432023-270

Silvikarina Erfanti Dewi Halim

{"title":"Acute Pancreatitis with Abdominal Bloating and Normal Transabdominal Ultrasound","authors":"Silvikarina Erfanti Dewi Halim","doi":"10.24871/2432023-270","DOIUrl":"https://doi.org/10.24871/2432023-270","url":null,"abstract":"Acute pancreatitis (AP) is an inflammatory disorder of the pancreas, and its correct diagnosis is an area of interest for clinicians. A 44-year-old man, presented with bloating for 1 month and getting worsened 1 day before admission to emergency room (ER), accompanied by discomfort in the upper left abdomen. The patient had abdominal distension, no vomiting or severe abdominal pain. Ultrasonography (USG) transabdominal revealed polyp gallbladder, no stone or pancreatitis. Magnetic resonance imaging (MRI) 2 months before at the ER, showed multiple stone in gallbladder and normal pancreas. Leukocytes 15 x 103/L, serum glutamic pyruvic transaminase (SGPT) 262, serum glutamic oxaloacetic transaminase (SGOT) 249, gamma glutamyl transferase (GGT) 1369 U/L, total bilirubin (TBIL) 2.44, direct bilirubin (DBIL) 2.08, lipase 14,690 U/L, amylase 3,693 U/L. Patient refused computerized tomography scan (CT scan) or MRI repeated, based on Atlanta criteria, abdominal discomfort with high amylase/lipase and a history of gallstones, the diagnosis was made. After 3 days, SGPT 44, SGOT 19, GGT 732 U/L, lipase 46 U/L, amylase 38 U/L. Based on Atlanta classification, AP diagnosed if at least 2 of the following 3 criteria are fulfilled: abdominal pain, serum lipase or amylase at least 3x the upper limit of normal (ULN) or characteristic findings on imaging. Gallstones are the most cause of AP. Abdominal bloating in this patient couldn’t be explained by common causes, such as ascites, bowel edema, hematoma, ileus which led us to suspect pancreatitis. CT scan contrast or MRI was essential in patients with normal USG and no classic sign abdominal pain.","PeriodicalId":515400,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy","volume":"23 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140489518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Diagnosis and Treatment of Choledocholithiasis 胆总管结石的当前诊断和治疗方法

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-01-29 DOI: 10.24871/2432023256

Kaka Renaldi, Fauzan Hertrisno Firman

引用次数: 0

Diagnostic Approach and Management of Clostridium difficile Infection 艰难梭菌感染的诊断方法和管理

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-01-29 DOI: 10.24871/2432023250

F. N. Hosea, Achmad Fauzi

引用次数: 0

Relationship between Helicobacter pylori Infection and Gastroesophageal Reflux Disease (GERD) 幽门螺杆菌感染与胃食管反流病（GERD）之间的关系

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-01-29 DOI: 10.24871/2432023201

Silvikarina Erfanti Dewi Halim

{"title":"Relationship between Helicobacter pylori Infection and Gastroesophageal Reflux Disease (GERD)","authors":"Silvikarina Erfanti Dewi Halim","doi":"10.24871/2432023201","DOIUrl":"https://doi.org/10.24871/2432023201","url":null,"abstract":"Background: Helicobacter pylori infection is a gastrointestinal infection that affects about 50% of the world's population, however, its prevalence varies across geographic areas. The actual relationship of H. pylori with gastroesophageal reflux disease (GERD) is still unclear because some studies report a high prevalence of H. pylori in GERD patients, but some studies report the opposite. This study aims to determine the relationship between H. pylori infection and GERD and the prevalence of Helicobacter pylori infection in GERD patients at Eka Hospital Pekanbaru.Method: This study was a cross-sectional study of GERD patients who had undergone endoscopy at Eka Hospital Pekanbaru from January 2021 to December 2022. There were 219 patients. This research was then analyzed with the chi-square test using SPSS version 22.Results: A total of 219 GERD patients met the criteria for this study. 108 of them were positive for H. pylori from the results of endoscopic biopsies. The prevalence of GERD patients infected with H. pylori is 49.3%. 108 of them were positive patients, 14 (13%) GERD patients were ≥ 60 years old and 94 (87%) were 60 years old. Of the 108 positive patients, 53 (49.1%) were male, 55 (50.9%) were female. Where age and gender did not significantly increase the risk of H. pylori infection (p 0.05). The most common endoscopic biopsy finding is chronic erosive gastritis.Conclusion: Although the prevalence of GERD patients infected with H. pylori was quite large (49.3%), there was no significant association between GERD patients and the incidence of H. pylori infection.","PeriodicalId":515400,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy","volume":"27 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140487974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ESOPHAGEAL VARICES REBLEEDING PROPHYLAXIS TREATMENT: WHO IS THE CHAMPION? 食管静脉曲张再出血预防治疗：谁是冠军？

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Pub Date : 2024-01-29 DOI: 10.24871/2432023193

C. R. A. Lesmana

引用次数: 0