Eurasian Journal of Chemistry最新文献_第2页

Eurasian Journal of Chemistry Pub Date : 2024-03-27 DOI: 10.31489/2959-0663/1-24-0

Eurasian Journal of Chemistry Editorial Board

{"title":"ABOUT NEW JOURNAL WEBSITE","authors":"Eurasian Journal of Chemistry Editorial Board","doi":"10.31489/2959-0663/1-24-0","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-0","url":null,"abstract":"Dear Colleagues, \u0000We are pleased to present new website https://ejc.buketov.edu.kz/ of the Eurasian Journal of Chemistry. Since February 2024, submission of manuscripts and publication of articles in the Eurasian Journal of Chemistry takes place on the new website. The archive of journal issues before 2023 can be found on the old website https://chemistry-vestnik.ksu.kz/archive. \u0000In 2023, our journal was rebranded and the journal title was changed from Bulletin of the Karaganda University. Chemistry Series on the Eurasian Journal of Chemistry, so our new website is located on a new domain, which corresponds to the new name of the journal. \u0000Our new website is based on the OJS international publishing platform, which is used worldwide to automate the publishing process of Open Access scholarly journals. Before submitting, Authors should Login to the site or Register. The article is submitted through the Online Article Submission System. Authors are advised to read the Author Guidelines and adhere to the Ethical Standards before submitting, Authors can use Template for the Article and Template for the Supplementary Materials to prepare submission. \u0000The Editorial Board of the Eurasian Journal of Chemistry hopes that the relocation to a new website will improve the journal’s interaction with Authors, Reviewers, Readers and other interested parties, and will also contribute to the further journal development and promotion at the international level.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"16 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140374101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantifying Curcumin, Gallic Acid, and Resveratrol in a Polyherbal Mixture: a Robust HPTLC Method 多草药混合物中姜黄素、没食子酸和白藜芦醇的定量：一种可靠的 HPTLC 方法

Eurasian Journal of Chemistry Pub Date : 2024-03-07 DOI: 10.31489/2959-0663/1-24-2

S. Gandhi, Gresi D. Mate, D. Nagore, S. Chitlange

{"title":"Quantifying Curcumin, Gallic Acid, and Resveratrol in a Polyherbal Mixture: a Robust HPTLC Method","authors":"S. Gandhi, Gresi D. Mate, D. Nagore, S. Chitlange","doi":"10.31489/2959-0663/1-24-2","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-2","url":null,"abstract":"The need for this study arises from the growing importance of polyherbal formulations in herbal medicine, particularly due to their potential health benefits and synergistic effects. In this research, development and validation of an HPTLC method for simultaneous quantification of curcumin, gallic acid, and resveratrol in a polyherbal mixture are primary focus. Additionally, study assesses the Total Phenolic Content (TPC), Total Flavonoid Content (TFC) and antioxidant potential using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The results reveal that TPC is 212.1 mg gallic acid equivalent per gram of plant material, and the TFC is 133.06 mg rutin equivalent per gram of plant material. Notably, DPPH assay demonstrates mixture's robust antioxidant activity, with an IC50 value of 3.83 µg/ml. Furthermore, HPTLC method used a carefully optimized mobile phase, providing excellent resolution for gallic acid, resveratrol, and curcumin with corresponding Rf values of 0.18, 0.43, and 0.53. This method is highly linear over a concentration range of 200-1000 ng/band for all three compounds. Precision studies confirm method's reproducibility with low Relative Standard Deviation values below 2 %. Ultimately, this HPTLC method offers a simple, accurate, precise, and cost-effective solution for routine quality control analysis, shedding light on potential applications of the polyherbal mixture in various therapeutic contexts.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140260385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Use of the Catalysts Based on Coal Ash Microsphere and Chrysotile in the Thermal Destruction of Primary Coal Tar 使用基于煤灰微球和温石棉的催化剂热分解原煤焦油

Eurasian Journal of Chemistry Pub Date : 2024-02-26 DOI: 10.31489/2959-0663/1-24-9

D. Aitbekova, M. Baikenov, Aigul Muratbekova, Abylaikhan N. Bolatbay, N. Balpanova, S. Tyanakh, Fengyun Ma, Tolkyn O. Khamitova

{"title":"The Use of the Catalysts Based on Coal Ash Microsphere and Chrysotile in the Thermal Destruction of Primary Coal Tar","authors":"D. Aitbekova, M. Baikenov, Aigul Muratbekova, Abylaikhan N. Bolatbay, N. Balpanova, S. Tyanakh, Fengyun Ma, Tolkyn O. Khamitova","doi":"10.31489/2959-0663/1-24-9","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-9","url":null,"abstract":"In order to evaluate the possibility of using different catalysts prepared for the hydrogenation process of primary coal tar, the method of differential thermal analysis was used, which allows to determine the kinetic parameters of thermal destruction, such as the rate constant, activation energy, and pre-exponential multiplier. The effect of catalysts on characteristics of mass loss during heating of \"Shubarkol Komir\" JSC primary coal tar at a constant speed (20 K/min) in a nitrogen medium has been considered. Microsphere, NiO/microsphere, CoO/microsphere, chrysotile and NiCo/chrysotile have been taken as catalytic additives. In the presence of the catalysts, the rate of thermal destruction of primary coal tar increases in the following order: CoO/microsphere < NiO/microsphere < NiCo/chrysotile. While microsphere catalysts extend the range of thermal destruction, chrysotile catalysts lead to the rapid completion of the destruction process. This fact is characterized by the formation of bonds between catalytic additives and primary coal tar. It is important to determine such parameters that affect on the activation energy and macrokinetics of the thermal decomposition process for prediction of catalyst activity during hydrogenation of heavy hydrocarbon raw materials.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140432028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hirshfeld Surfaces Analysis of Intermolecular Interaction in the Series of Steroid Hormone Molecular Crystals 类固醇激素分子晶体系列中的分子间相互作用的赫什菲尔德表面分析

Eurasian Journal of Chemistry Pub Date : 2024-02-26 DOI: 10.31489/2959-0663/1-24-8

N. Karaush-Karmazin, B. Minaev, V. Minaeva, Olexandr O. Panchenko, Hans S. Ågren

{"title":"Hirshfeld Surfaces Analysis of Intermolecular Interaction in the Series of Steroid Hormone Molecular Crystals","authors":"N. Karaush-Karmazin, B. Minaev, V. Minaeva, Olexandr O. Panchenko, Hans S. Ågren","doi":"10.31489/2959-0663/1-24-8","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-8","url":null,"abstract":"In this work Hirshfeld surface analysis is performed on the crystallographic-characterized crystal cells of the progesterone, 17α-hydroxyprogesterone, and testosterone hormones. The Hirshfeld surfaces are mapped for a detailed visualization of the electron density distribution around a molecule to understand the atomic-pair close contacts and interaction types within a crystal structure of the studied hormones. The intermolecular forces, including Van der Waals forces, hydrogen bonding, and C–H···π interactions, play essential roles in determining the supramolecular arrangement of all the three molecules in their crystals. These forces contribute to the cohesion, stability, and structural organization of the crystals, ultimately influencing their properties and behaviour in various applications. Two-dimensional fingerprint plots with detailed information about the contribution of each contact to the total Hirschfeld surface allowed to provide a visual representation of the relative importance (in %) of identified intermolecular О···Н/H···O, C···Н/H···C, H···Н interactions within a crystal structure of the studied hormones in the context of “molecule-substance” relations.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"48 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140431534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient Ion-Exchange Resin Catalysts for the Liquid-Phase Selective Hydrazinolysis of Succinic Acid 用于丁二酸液相选择性肼解的高效离子交换树脂催化剂

Eurasian Journal of Chemistry Pub Date : 2024-02-23 DOI: 10.31489/2959-0663/1-24-5

S. Dzhumadullaeva, A. Baeshov

{"title":"Efficient Ion-Exchange Resin Catalysts for the Liquid-Phase Selective Hydrazinolysis of Succinic Acid","authors":"S. Dzhumadullaeva, A. Baeshov","doi":"10.31489/2959-0663/1-24-5","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-5","url":null,"abstract":"Dicarboxylic acid dihydrazides are widely used as pharmaceutical intermediates, plant growth regulators, water-based coating additives, epoxy crosslinking agents. Dihydrazides are prepared by adding hydrazine hydrate to an acid halides and diesters. In this work the hydrazinolysis of succinic acid was studied using various ion exchange resins as catalysts, and the optimum conditions and the reaction mechanism were identified. Analysis of the initial reagents and the target product were performed out using photocolorimetric and IR spectroscopic methods, the composition of the target product was determined by elemental analysis. Hydrazinolysis of succinic acid were performed in aqueous medium in the temperature 90 °C for 3 h. Succinic acid conversion was 82–95 %, and the succiniyldihydrazide yield 61–93 %. It has been shown the efficient catalysts for the hydrazinolysis of succinic acid are AV-17-8, AN-31 and AN-1 anion exchangers. The highest succinyldihydrazide yield (93 %) was obtained with anion exchanger AV-17-8. On the basis of IR spectroscopic studies, a plausible process mechanism was suggested. A probable mechanism of the process with the formation of supramolecular complexes with the participation of substrates and fixed polymer-bound quaternary ammonium and hydroxyl ions of the anion exchanger was proposed. Thus, the most efficient method of succinic acid dihydrazide preparation has been proposed in comparison with known methods.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"22 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140437286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Optimization of Bovine Serum Albumin Nanoparticles Immobilized with Antituberculosis Drugs 用抗结核药物固定牛血清白蛋白纳米粒子的合成与优化

Eurasian Journal of Chemistry Pub Date : 2024-02-23 DOI: 10.31489/2959-0663/1-24-6

Nazgul A. Yessentayeva, Aldana R. Galiyeva, A.Т. Daribay, D. Sadyrbekov, T. Zhumagalieva, Dias T. Marsel

{"title":"Synthesis and Optimization of Bovine Serum Albumin Nanoparticles Immobilized with Antituberculosis Drugs","authors":"Nazgul A. Yessentayeva, Aldana R. Galiyeva, A.Т. Daribay, D. Sadyrbekov, T. Zhumagalieva, Dias T. Marsel","doi":"10.31489/2959-0663/1-24-6","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-6","url":null,"abstract":"This study involved the synthesis of bovine serum albumin (BSA) nanoparticles immobilized with the antituberculosis drugs isoniazid (INH) and rifampicin (RIF) by the desolvation method. The primary objective was to explore the impact of varying concentrations of albumin, urea, cysteine, rifampicin, and isoniazid on the average size of nanoparticles, polydispersity, and the encapsulation efficiency of drugs. The study's outcomes affirm that alterations in the concentrations of these components influence nanoparticles’ parameters, highlighting their key role in optimizing the encapsulation process and enhancing the efficacy of tuberculosis drug delivery. The nanoparticles obtaned as a result of optimization demonstrated an optimal size of 231.2±1.2 nm with a polydispersity of 0.061±0.08. Encapsulation efficiency was 89% for rifampicin and 38.5% for isoniazid. The investigation of drug release kinetics from the polymer matrix revealed a gradual release pattern. Evaluation of the obtained nanoparticles by Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) confirmed the successful incorporation of drugs into the polymer matrix. These findings highlight the potential of BSA nanoparticles as effective carriers for tuberculosis treatment, with implications for refining drug delivery strategies.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"13 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140437422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the Bromination of Diethyl 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate: the True Structure of the Halbig’s Product 论 3,5-二甲基-1H-吡咯-2,4-二甲酸二乙酯的溴化作用：哈尔比希产物的真实结构

Eurasian Journal of Chemistry Pub Date : 2024-02-22 DOI: 10.31489/2959-0663/1-24-4

L. Salkeyeva, L. М. Pevzner, Pavel Vojtíšek, Yelena V. Minayeva

{"title":"On the Bromination of Diethyl 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate: the True Structure of the Halbig’s Product","authors":"L. Salkeyeva, L. М. Pevzner, Pavel Vojtíšek, Yelena V. Minayeva","doi":"10.31489/2959-0663/1-24-4","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-4","url":null,"abstract":"Pyrrole and its derivatives have attracted the attention of researchers as promising objects of practical importance in various areas of human life. Focusing on Knorr pyrrole as the most readily available pyrrole derivative, our objective was to obtain its bromo derivatives, containing an allyl bromine atom followed by phosphorylation reactions. The reaction involving bromination was carried out with 2 mol of N-bromosuccinimide per 1 mol of Knorr pyrrole 1 in carbon tetrachloride. This reaction was initiated with azobis(isobutyronitrile) and carried out at a boiling point. In acetic acid, the bromination reaction was carried out at a temperature of 38-45°C with a molar ratio of Knorr pyrrole to bromine of 1:4 and another reaction was carried out at 40-50°C with a molar ratio of Knorr pyrrole to bromine of 1:5. The bromination reaction was also performed in chloroform at 27-30°C in the presence of catalytic amounts of aluminum chloride. The same crystalline product was obtained in all cases. X-ray diffraction analysis revealed that the single crystal structure is diethyl 5-(dibromomethyl)-3-methyl-2-oxo-2,3-dihydro-1H-pyrrole-3,4-dicarboxylate 5 with two bromine atoms. This composition is identical to that of the Halbig product. It was found that the bromination of Knorr pyrrole 1 occurs stepwise with excess N-bromosuccinimide and bromine, resulting in the unsaturated lactam 5, commonly known as Halbig’s product. The true structure of product 5 was determined.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140439118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Synthesis of 2-Aminopyrimidines by Amination of Biginelli Reaction Products — Oxadiazocines 通过氨基化 Biginelli 反应产物合成 2-氨基嘧啶的新方法 - Oxadiazocines

Eurasian Journal of Chemistry Pub Date : 2024-02-22 DOI: 10.31489/2959-0663/1-24-11

D.M. Turgunalieva, I. Kulakov

{"title":"New Synthesis of 2-Aminopyrimidines by Amination of Biginelli Reaction Products — Oxadiazocines","authors":"D.M. Turgunalieva, I. Kulakov","doi":"10.31489/2959-0663/1-24-11","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-11","url":null,"abstract":"Abstract Previously, we synthesized methanobenzo[g][1,3,5]oxadiazocines and methanonaphtho[2,3-g][1,3,5]oxadiazocines via the Biginelli reaction using thiourea with acetoacetic ester or acetylacetone and salicylaldehyde or 2-hydroxy-1-naphthaldehyde under acidic catalysis and microwave irradiation. These compounds were then subjected to alkylation reaction with ethyl bromide in the presence of potassium carbonate in dimethylformamide. Under these mild reaction conditions, possible thione-thiol tautomerism of the oxadiazocines, as well as their structural analogs of cyclic thioureas, predominantly yielded in S-alkylation products with minor amounts of N-alkylation products. Further nucleophilic substitution reactions of S-ethyl-methanobenzo[g][1,3,5]oxadiazocines and S-ethyl-methanonaphtho[2,3-g][1,3,5]oxadiazocines revealed that alongside nucleophilic substitution by morpholine, elimination of phenol or naphthol occurred, followed by aromatization of the dihydropyrimidinone ring into an aromatic pyrimidine ring, resulting in the formation of 2-morpholinyl-substituted pyrimidines. Only a few examples and multi-step syntheses for obtaining such 2-amino-substituted pyrimidines are presented in the literature. Therefore, our newly discovered method for obtaining widely demanded derivatives of 2-aminopyrimidines is presented both relevant and promising.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"67 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140439971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural Studies and Applications of Sulfobetaine-Based Polybetaines at Interfaces 基于磺基甜菜碱的聚贝塔酯在界面上的结构研究和应用

Eurasian Journal of Chemistry Pub Date : 2024-02-22 DOI: 10.31489/2959-0663/1-24-3

Arshyn Zhengis, Yenglik Amrenova, Arailym Yergesheva, D.K. Kanzhigitova, Gulim Imekova, Zhexenbek Toktarbay, O. Toktarbaiuly, Munziya Abutalip, N. Nuraje

{"title":"Structural Studies and Applications of Sulfobetaine-Based Polybetaines at Interfaces","authors":"Arshyn Zhengis, Yenglik Amrenova, Arailym Yergesheva, D.K. Kanzhigitova, Gulim Imekova, Zhexenbek Toktarbay, O. Toktarbaiuly, Munziya Abutalip, N. Nuraje","doi":"10.31489/2959-0663/1-24-3","DOIUrl":"https://doi.org/10.31489/2959-0663/1-24-3","url":null,"abstract":"The main goals of this research endeavor are to enhance the hydrophilic properties and water permeability of a nanofiltration membrane. This is achieved by incorporating a Zeolitic imidazolate framework (ZIF-8) layer that has been stabilized utilizing a redox-grafted methacrylate hydrogel. The decision to use polyacrylonitrile (PAN) as the substrate material was motivated by its intrinsic hydrophilic properties, which contribute to its ability to resist fouling and promote water permeability. The shift of the surface from hydrophilic to superhydrophilic was confirmed using physicochemical evaluations, including scanning electron microscopy (SEM) and contact angle measurements. Hydrolyzed Polyacrylonitrile Zeolitic imidazolate framework grafted (HPANZifG) membrane exhibited a remarkably high-water flux of 82.3 L/m2 Bar hour, which is an achievement of notable significance. This study makes a valuable contribution to the advancement of nanofiltration technology by proposing potential solutions to the challenges faced in the field of water purification and treatment.","PeriodicalId":514223,"journal":{"name":"Eurasian Journal of Chemistry","volume":"20 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140442143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0