European Journal of Health Economics最新文献

{"title":"Psychological distress and productivity loss: a longitudinal analysis of Australian working adults.","authors":"Syed Afroz Keramat, Tracy Comans, Alison Pearce, Rabeya Basri, Rubayyat Hashmi, Nadeeka N Dissanayaka","doi":"10.1007/s10198-025-01764-9","DOIUrl":"https://doi.org/10.1007/s10198-025-01764-9","url":null,"abstract":"<p><p>By 2030, it is anticipated that poor mental health will cost the global economy approximately $6 trillion per year, primarily due to productivity loss. It is crucial to understand how psychological distress contributes to productivity loss in the workplace. We aim to investigate the relationship between psychological distress and productivity loss in the Australian working population. We utilized eight waves of longitudinal data drawn from the Household, Income, and Labour Dynamics in Australia (HILDA) Survey (waves 7, 9, 11, 13, 15, 17, 19, and 21). We compiled an unbalanced panel data set comprising 70,973 person-year observations from 18,729 unique working adults. We used Fixed-effects Poisson regression and Fixed-effects logistic regression models to investigate the within-person differences in the relationship between psychological distress and productivity loss (measured through sickness absence, presenteeism, and underemployment). We found that moderate and high psychological distress is associated with a higher rate of sickness absence, presenteeism, and underemployment when a working adult shifted from low psychological distress after controlling socio-demographic, health, and employment-related characteristics. Our study demonstrated that moderate to high psychological distress adversely affected employees' job productivity through increased sickness absence, a higher likelihood of presenteeism, and greater levels of underemployment. Our findings also revealed that employees with moderate and high psychological distress incurred additional annual sickness absence costs of AUD 60.66 and AUD 99.26, respectively, compared to peers with low psychological distress. Additionally, our study found that employees with moderate and high levels of psychological distress experienced significantly higher levels of presenteeism, which resulted in additional annual costs of AUD 1,166.30 and AUD 3,656.05, respectively, compared to their counterparts with low psychological distress. Psychological distress imposed significant costs on Australian workplaces. Implementing workplace health promotion programs should be prioritized as a policy to address psychological distress among employees, enhance their well-being, and improve overall productivity.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compliance with clinical guidelines: the role of incentives and competition between practitioners.","authors":"Gianluca Fiorentini, Luke B Connelly","doi":"10.1007/s10198-025-01784-5","DOIUrl":"https://doi.org/10.1007/s10198-025-01784-5","url":null,"abstract":"<p><p>In this study we use a unit record, panel dataset, to examine the behaviour of clinicians under a chronic disease management program (CDMP) that is designed to improve care and slow the progression of chronic kidney disease (CKD). Using 8 years of quarterly data on the population of CKD patients (n = 44,686) in the Emilia-Romagna region of northern Italy, we analyse a setting where medical practitioners are agents who respond to the demands of two principals: their patient and the third-party payer. Exploiting detailed information on specialist visits and the concentration of general practitioners (GP) in local areas, as well as disease severity, we study how GPs on one side, and specialist nephrologists and cardiologists on the other comply with the CDMP guidelines, as may be predicted on the basis of a dual-agency approach. Our application of both multiple-treatment differences-in-differences (DID_M) and panel fixed-effects linear probability models produces evidence coherent with income-maximizing and, to a lower extent, effort-reducing strategies on the part of the GPs, as well as with strategic behaviour by some specialists. We also produce evidence that specialists who practice in hub facilities with a leading role in CDMP implementation, also for reputational reasons, exhibit referral practices that are more closely related to the CDMP guidelines.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of myelodysplastic syndromes: a systematic literature review of economic burden.","authors":"Preston Tse, Shitong Xie, Jiajun Yan, Brittany Humphries, Feng Xie","doi":"10.1007/s10198-025-01779-2","DOIUrl":"https://doi.org/10.1007/s10198-025-01779-2","url":null,"abstract":"<p><strong>Objective: </strong>To identify and synthesize available evidence on the economic burden for myelodysplastic syndromes (MDS).</p><p><strong>Methods: </strong>A systematic search was conducted in EMBASE and MEDLINE on July 13, 2021 to identify studies that report original data on the economic burden of MDS. Included studies were reviewed independently and in duplicate by two reviewers. Data on study design, patient characteristics and economic burden were extracted using a standardized form developed by the team. All costs were converted to 2023 USD and then a descriptive analysis was conducted.</p><p><strong>Results: </strong>77 publications from 61 unique studies reporting the economic burden of MDS were identified. Most were database studies (n = 34, 55.7%) and were conducted in the United States (n = 34, 55.7%). The most common outcome considered was total costs for MDS (n = 32, 52.5%). Total annual costs ranged from $6777 to $521,141 and differed according to treatment modality [best supportive care versus hypomethylating agents (HMAs)] and patient status (risk status and transfusion dependent). Broadly, costs were greater among patients with high-risk MDS compared to low-risk patients as well as those receiving HMAs and transfusions. Other costs and resource use outcomes (outpatient, inpatient costs, etc.) were not directly comparable across studies due to heterogeneity and lack of reporting of cost components.</p><p><strong>Conclusion: </strong>This systematic literature review provides insight into the economic burden of MDS, which can be substantial. More research is needed to explore specific cost components as well as economic outcomes among subgroups of patients, such as newly diagnosed patients or patients classified as high risk.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of displaying laboratory test prices on physicians' ordering behaviour: a systematic review of European studies.","authors":"Katrine Villaume Roedbro, Signe Smith Jervelund","doi":"10.1007/s10198-025-01781-8","DOIUrl":"https://doi.org/10.1007/s10198-025-01781-8","url":null,"abstract":"<p><strong>Objective: </strong>As European healthcare systems struggle with increasing workload and sustainability issues, it is estimated that 20% of their production is ineffective. One potential strategy to reduce this excess is by minimizing the use of unnecessary laboratory tests. The aim of this review was to investigate the effect of presenting physicians in Europe with the cost of laboratory tests at the time of ordering on the quantities and expense of laboratory tests as well as to identify knowledge gaps on this matter.</p><p><strong>Methods: </strong>Following PRISMA guidelines, a systematic search in PubMed and EMBASE was conducted in February 2025. Studies were included if written in English and conducted in Europe. There were no restrictions on year of publication. Study quality was evaluated using a modified Downs and Black checklist.</p><p><strong>Results: </strong>Of the 2185 publications identified, five met the inclusion criteria. All included studies were published 2002-2021 and found a reduction in order cost and/or volume of laboratory test, following price display (four with statistically significant results). The reduction in order costs were greater than the reduction in order volume. Additionally, the impact of price display diminished over time as the intervention period continued. None of the studies included patient safety measures.</p><p><strong>Conclusions: </strong>Price display is a simple yet potentially impactful intervention as it is likely to reduce both the cost and volume of tests, thereby decreasing the workload and enhancing the sustainability of the healthcare systems. Further high-quality studies are needed to determine if price display is a patient-safe intervention.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deterioration of health-related quality of life: the hidden health burden of informal caregiving.","authors":"Syed Afroz Keramat, Prianka Maria Sarker, Tracy Comans, Deborah Brooks, Nadeeka N Dissanayaka","doi":"10.1007/s10198-025-01776-5","DOIUrl":"https://doi.org/10.1007/s10198-025-01776-5","url":null,"abstract":"<p><p>Informal caregiving is physically and mentally demanding and may lead to poor health and impaired well-being. We aim to check the effects of informal caregiving on health-related quality of life (HRQoL). We utilised longitudinal data from the most recent sixteen waves of the Household, Income and Labour Dynamics in Australia (HILDA) Survey. We measured HRQoL through the physical component summary (PCS), the mental component summary (MCS), the short-form six-dimension (SF-6D) utility index, and the eight dimensions of the SF-36 health survey. The primary exposure variable is informal caregiving. The variable was categorised into not a caregiver, lighter (< 5 hours [h]/week), moderate (5-19 h/week), and intensive (≥ 20 h/week) caregiving based on the hours of providing informal care per week. We have found that informal caregiving negatively affects HRQoL. We found that moderate (β = -0.0035, standard error [SE] = 0.0012) and intensive caregiving (β = -0.0074, SE = 0.0020) reduced SF-6D utility value. We also found that lighter (β = -0.29, SE = 0.07), moderate (β = -0.55, SE = 0.12), and intensive (β = -1.53, SE = 0.19) caregiving lowered MCS scores. Moreover, our results revealed that lighter, moderate and intensive caregiving decreases the scores of mental health-related dimensions (e.g., role emotional, social functioning, and mental health) of the SF-36 health survey. Our study findings have significant policy implications for improving the HRQoL and well-being of caregivers. To effectively support the health and well-being of informal carers, it is crucial to implement strategies that address their diverse needs, including supporting work-life balance, providing financial assistance and social security measures, ensuring access to community-based services, providing access to relevant information and training, and offering respite care options.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How a nation's well-being influences its health profile: an analysis of critical indicators.","authors":"Iulia Cristina Iuga, Raluca Andreea Nerişanu, Horia Iuga","doi":"10.1007/s10198-025-01777-4","DOIUrl":"https://doi.org/10.1007/s10198-025-01777-4","url":null,"abstract":"<p><p>This study examines the impact of macroeconomic well-being indicators-GDP, health spending as a percentage of GDP, and the unemployment rate-on the prevalence of chronic diseases, including circulatory and respiratory diseases and diabetes mellitus, across 27 European Union countries over 21 years. Utilizing advanced econometric methods like General Method of Moments, Structural Equation Modeling, and wavelet coherence analysis, the research reveals that higher GDP correlates with increased disease prevalence, while greater health spending reduces it. The unemployment rate significantly affects diabetes prevalence. The study introduces the \"Economic Prosperity and Chronic Disease Paradox,\" theory, which suggests that economic growth, while improving healthcare access and living standards, paradoxically increases chronic disease rates due to lifestyle changes such as unhealthy diets, sedentary behavior, and pollution. This theory highlights the need for strategic public health policies to counteract these adverse effects and promote sustainable health outcomes amidst economic development.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does timing matter? The role of health information shocks in measuring willingness to pay.","authors":"Carolin Brinkmann, Sebastian Neumann-Böhme, Werner B F Brouwer, Tom Stargardt","doi":"10.1007/s10198-025-01774-7","DOIUrl":"https://doi.org/10.1007/s10198-025-01774-7","url":null,"abstract":"<p><strong>Objectives: </strong>The optimal point in time to measure willingness-to-pay (WTP) remains unclear. We investigated the role of health information shocks (HIS) in individuals' WTP, analyzing the extent to which news of SARS-CoV-2 infections among people they know/themselves altered WTP for booster vaccinations.</p><p><strong>Methods: </strong>We elicited WTP in eight European countries using the European Covid Survey. First, we presented participants with a hypothetical setting recommending a booster vaccination that had to be paid out-of-pocket. To measure WTP, we elicited a lower and upper WTP limit, and a WTP value contingent on both of these. To measure HIS, we asked about the duration since participants received news of COVID-19 cases among people they know (including themselves), as well as the degree of personal connection to these cases and their severity. We used a two-part model to estimate the association between HIS and individuals' WTP.</p><p><strong>Results: </strong>Among the 5809 observations, 76.8% stated a WTP for a booster vaccination greater than €0. At least one HIS was reported by 61.9% of participants. The occurrence of a HIS was associated with an increase in WTP of €14.54 (logistic: P <.0001, gamma: P =.1493) compared to no HIS. The WTP was higher when the HIS occurred in the four weeks before the survey. Controlling for socio-demographic and COVID-19 covariates decreased significance and effect sizes.</p><p><strong>Conclusion: </strong>Our findings suggest that a recent HIS is associated with a higher probability of having a positive WTP. Timing, in relation to some relevant event, therefore may matter when measuring WTP for health interventions. If so, finding the optimal point in time to measure WTP is difficult and may depend on the policy question under consideration.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of minimum important changes for generic multi-attribute utility instruments and recommendations for their estimation.","authors":"Glen J Henson, Ingrid van der Mei, Bruce V Taylor, Paul Scuffham, Gang Chen, Julie A Campbell","doi":"10.1007/s10198-025-01778-3","DOIUrl":"https://doi.org/10.1007/s10198-025-01778-3","url":null,"abstract":"<p><strong>Introduction: </strong>Minimum important changes (MICs) represent thresholds for clinically meaningful change. Multi-attribute utility instruments (MAUIs) generate health state utilities (holistic measures of health-related quality of life). No systematic review of MICs specifically for MAUIs has been conducted. In addition, no guidelines for estimating MICs for MAUIs have been proposed. We aimed to correct these evidence gaps by producing guidelines contextualised by a systematic review.</p><p><strong>Methods: </strong>We searched ten databases for relevant records using various search terms. Extracted data were analysed narratively and descriptively. The presence of key reporting items (relating to precision, sensitivity, and concurrent validity) was also evaluated. Guidelines for MIC estimation were informed by the broader MIC literature and contextualised using study results.</p><p><strong>Results: </strong>The review identified 5035 non-duplicate records, with 68 entering the study. 282 unique, anchor-based MICs were extracted. Of these MICs, 119 (42.20%) pertained to the EQ-5D-3L, 82 (29.08%) to the EQ-5D-5L, and 50 (17.73%) to the SF-6D.v1. The most common anchor-based method used to estimate MICs (107, 37.94%) involved taking the mean change score for a group considered to have experienced a MIC. Distribution-based methods were also common, appearing in 31 (45.59%) of the included studies. The inclusion of key reporting items was generally deficient.</p><p><strong>Conclusions: </strong>Deficiencies in reporting and diverse estimation methods raise concerns regarding the extant MAUI MIC literature. Researchers should exercise caution when using existing MAUI MICs. Recommendations presented in our study may assist researchers in effectively estimating MICs for use in health economics.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the measurement properties of the EQ-5D-Y-3L, EQ-5D-Y-5L and CHU9D in children and adolescents: a measurement property study.","authors":"Caique de Melo do Espirito Santo, Verônica Souza Santos, Yasmin Brasileiro de Souza, Aureliano Paolo Finch, Janine Verstraete, Gisela Cristiane Miyamoto, Tiê P Yamato","doi":"10.1007/s10198-025-01770-x","DOIUrl":"https://doi.org/10.1007/s10198-025-01770-x","url":null,"abstract":"<p><strong>Background: </strong>The EQ-5D-Y-3L, EQ-5D-Y-5L and Child Health Utility 9-dimension (CHU9D) are instruments that measures health-related quality of life. These instruments are widely used in children and adolescents with health conditions, however the measurement properties of the three instruments have not been tested in Brazilian children.</p><p><strong>Objective: </strong>To compare and test the measurement properties of the EQ-5D-Y-3L, EQ-5D-Y-5L and CHU9D in Brazilian children and adolescents with and without any self-reported musculoskeletal pain.</p><p><strong>Methods: </strong>Children and adolescents aged 8-18 years were recruited from schools in Sao Paulo, Brazil and, self-completed the EQ-5D-Y-3L, EQ-5D-Y-5L and CHU9D at baseline and after 7 days. Reliability was determined by Kappa for the dimensions and intraclass correlation coefficient (ICC) for visual analogue scale (EQ VAS). Hypothesis were developed for construct validity and tested with Spearman and Pearson correlations (adequate if > 75% of the hypotheses confirmed). Children and adolescents with and without musculoskeletal pain were compared for known-group validity.</p><p><strong>Results: </strong>We included 356 children and adolescents, with 51% (n = 181) reporting musculoskeletal pain. Majority were male (53%) and mean age of 11.5 years (SD: 2.9). The EQ-5D-Y-3L, EQ-5D-Y-5L and CHU9D ranged from poor to moderate reliability. Reliability of the EQ VAS was substantial (ICC: 0.81, 95% confidence interval [CI]: 0.72 to 0.87) to moderate (ICC: 0.40, 95% CI: 0.24 to 0.53) for those with musculoskeletal pain and without pain, respectively. In those with musculoskeletal pain the association was weak to moderate, with > 75% of hypotheses confirmed, when comparing EQ-5D-Y-3L and EQ-D-Y-5L with the PedsQL™ and comparing EQ-5D-Y-5L with CHU9D. All instruments were able to discriminate those with and without musculoskeletal pain.</p><p><strong>Conclusion: </strong>All instruments had better measurement properties in children and adolescents with musculoskeletal pain, compared to those without for reliability and construct validity. These instruments could be used to assess health-related quality of life in Brazilian children and adolescents with musculoskeletal pain.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loss aversion in EQ-5D-Y-3L: does it explain differences in willingness to trade-off life years in adults and children?","authors":"Ava F H Hoogenboom, Stefan A Lipman","doi":"10.1007/s10198-025-01775-6","DOIUrl":"10.1007/s10198-025-01775-6","url":null,"abstract":"","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}