Hanan Sajjad AL-Iedani, Jafar Abass, Issa Al-Maamori, A. Rheima
{"title":"The effects of ZnO-insulin nanoparticles on some oxidative stress biochemical and physiological markers in rats with alloxan-induced diabetes","authors":"Hanan Sajjad AL-Iedani, Jafar Abass, Issa Al-Maamori, A. Rheima","doi":"10.31185/jwsm.499","DOIUrl":"https://doi.org/10.31185/jwsm.499","url":null,"abstract":"In recent years, there has been a growing emphasis on nanomaterials, particularly in the realm of medical applications. Zinc oxide nanoparticles are widely recognized as a significant class of oxides of metals due to their inherent structural stability, little toxic effects, and ability to maintain cellular integrity. One of the most important medicinal uses of zinc oxide is medication administration. Twenty-four male albinos’ rats were randomly separated into four groups. Control group, diabetic group, diabetic group treated with insulin, and diabetic group treated with ZnO NPs loaded with insulin. The rats were given medication for 28 days. Diabetes mellitus was induced in the rats with blood sugar levels more than 250 mg/dL by administering alloxan intraperitoneally at a dose of 120 mg/kg. The nanoparticles' physicochemical properties were investigated using a variety of analytical techniques, including UV-Vis spectral analysis, X-ray diffraction (XRD), and Field Emission Scanning Electron Microscopy (FE-SEM). The data revealed significant increases in glucose, cholesterol, triglyceride and total oxidative stress (TOS) as well as a notable decrease in body weight and catalase levels, in the diabetic control group compared to the healthy control group (P< 0.05). Compared to control groups, ZnO NPs loaded with insulin lower total cholesterol, triglycerides and TOS on the other hand increase body weight and catalase levels. The results of our study indicate that the use of photo-synthesized ZnO-NPs in combination with insulin showed noteworthy antidiabetic benefits when compared to the control groups.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":" 92","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141827470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identification of Candidate Transcription Factors that Bind to the ASCN Gene, Associated with Parkinson's Disease, Using Bioinformatics Analysis","authors":"Muna A. Abdal Rhida","doi":"10.31185/jwsm.495","DOIUrl":"https://doi.org/10.31185/jwsm.495","url":null,"abstract":"Parkinson's disease (PD) is a neurodegenerative illness marked by progressive damage of dopaminergic neurons in the substantia nigra. Synuclein-α protein plays a key role in this term by aggregating in clumps of Lewy bodies causing PD. Despite unclear etiology of PD, growing indications show that PD pathogenesis is associated with gene expression dysregulation. Transcription factors (TFs) are the key players in regulating gene expression. In this study, we employed a bioinformatics tool to predict TF binding to Synuclein-α (SNCA)gene utilizing DNA sequences, epigenetic modifications, TF binding motifs, and creating machine learning algorithms. PROMO database was utilized to identify candidate TFs. Here we found TFs that act as regulators of neuronal function and dopaminergic signaling pathways, including members of the Forkhead box family, and nuclear factor-kappa B family members such as c-Jun, and STATs family. These findings provide a better understanding of the molecular mechanisms underlying PD disease and determine potential therapeutic targets.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":"13 S15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141377899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study the Effect of “Di-dodecyl amine” as a Corrosion Inhibitor for Carbon Steel in HCl Medium","authors":"Amel D. Hussein, Raheem A. H. Al-Uqaily","doi":"10.31185/jwsm.491","DOIUrl":"https://doi.org/10.31185/jwsm.491","url":null,"abstract":"Numerous organic compounds have been investigated for their potential to reduce corrosion under various circumstances. This study investigated the effects of di-dodecyl amine, an organic chemical, on carbon steel metal corrosion at different temperatures while HCl acid was present. The examination was carried out using accepted methods for polarization, weight loss, and corrosion process testing. The obtained findings demonstrated that the corrosion rate reduces with increasing inhibitor concentration, leading to increased inhibition efficiency. Furthermore, as shown in the weight loss technique, the corrosion rate lowers with increasing surface coverage with organic inhibitor at 313 °C. In the anodic and cathodic polarization methods, as well as in the inhibition efficiency, it is observed to see the cathodic and anodic curves through which the occurrence of the potential and corrosion current is known. The current and corrosion potential decreases with increasing inhibitor concentration. The amines and methyl motiveless in this inhibitor's composition give it their efficacy since they may coat the metal surface and stop corrosion","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":" 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140990706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study The Thermal Conductivity of Polymethyl Methacrylate Reinforcing with Cotton, Hair, and Burlap","authors":"Zuhair Salim Khamees, Asmaa Shawqy Khaleel","doi":"10.31185/jwsm.492","DOIUrl":"https://doi.org/10.31185/jwsm.492","url":null,"abstract":"This study includes the manufacture of two sets of composite materials consisting of polymethyl methacrylate reinforced with natural fibers. The first (R) group included eight layers of cotton with one layer of hair in the middle, and the second (O) group included six layers of cotton with three layers of burlap in the middle. The thermal conductivity of the two groups was checked using a Lee disc to identify the thermal conductivity (K), of group R 0.0771 w/m.c, and of group O 0.0754 w/m.c. These values are considered good as the material has good thermal insulation due to its low thermal conductivity values and is therefore suitable for use in prosthetic limbs as it can preserve the body temperature from external influences.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140990819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eco-Friendly Production of Metal Nanoparticles Through Plant Extract Besides Their Assessment of Antibacterial, and Antifungal activity","authors":"Nasser Nafaa, Abrahem Alqurashy","doi":"10.31185/jwsm.488","DOIUrl":"https://doi.org/10.31185/jwsm.488","url":null,"abstract":"A green-synthesis method for silver nanoparticles (Ag NPs) is a scientific breakthrough. Using sunflower plant extracts, this approach uses metallic and botanical synergy. Naturally occurring and renewable extracts reduce, chelate, stabilize, bind, and precipitate. The Ag nanoparticles' X-ray diffraction (XRD) crystal structure was cubic. Average nanoparticle crystallite size was 31.18 nm. Energy-dispersive X-ray spectroscopy (EDX) detected silver. Field Emission Scanning Electron Microscope (FESEM) examination revealed that the particles were Ag (silver) and spherical, averaging 31.23nm. Diffuse Reflectance Spectroscopy also indicated a 2.7 eV optical gap. Using many characterization methods, nanostructured silver was synthesized during this procedure. Biological efficacy assays can evaluate hierarchically porous silver's antibacterial properties. In the previous five years, strategies against Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus mutans, Ecoli, and Candida albicans, Penicillium spp., and Aspergillus spp. were essential. Data demonstrates that these structures are attractive antibacterial choices. A majority of Ag NPs are natural bacterium substitutes for Staphylococcus aureus, pseudomonas aeruginosa, Streptococcus mutans, and Ecoli. Also against various fungi: The immune systems of immunocompromised hosts are threatened by yeasts such Candida albicans, Penicillium, and Aspergillus.measured. It calls into doubt the study's efficacy in antibacterial and other applications.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140999573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salam Hussein, Talib, Firas Ali, Hussein Mohammed Khlaif, Challab
{"title":"Using Phragmites australis plants as activated carbon to remove Mn(II), and Cu(II) ions from different aqueous solutions","authors":"Salam Hussein, Talib, Firas Ali, Hussein Mohammed Khlaif, Challab","doi":"10.31185/jwsm.490","DOIUrl":"https://doi.org/10.31185/jwsm.490","url":null,"abstract":"This study investigates the use of agricultural byproducts of plants (Phragmites australis) as low-cost adsorbents for the removal of Cu2+ and Mn2+ from their aqueous solutions through the production of (AC). The results showed that the adsorption equilibrium time for both ions was 30 minutes. The results obtained showed that pH=5, pH=6 for Cu2+ and Mn2+ respectively were optimum to adsorption for these ions. The study showed that the weight (0.5 g) of the adsorbent was ideal to achieve the best adsorption and the ability of the adsorbents to adsorb metal ions was as follows: Cu(II) > Mn(II).","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":" 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141001048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical, Structural, and Morphological Characterization of Titanium Oxide (TiO2) Nanoparticles from Laser Ablation in Deionized Water","authors":"Najlaa Jerjack","doi":"10.31185/jwsm.489","DOIUrl":"https://doi.org/10.31185/jwsm.489","url":null,"abstract":"In this research, we focus on the synthesis of titanium oxide (TiO2) nanoparticles using the Nd:Utilization of YAG laser pulse ablation technique in liquid environments, with pulse energies from 100 to 500 millijoules. The process employs a Nd:YAG laser operating at a frequency of 6 Hz and a wavelength of 1064 nm. (The TiO2 nanoparticles synthesized in this study could be used in different high-temperature environments, as they are characterized by favorable physical, chemical, and mechanical properties). The synthesized product was further treated by calcination for four hours at temperatures higher than 600°C which promoted crystalline structure in the lattice. Comprehensive analyses were carried out to determine the nanoparticles' features. Optical features were studied through UV-visible spectroscopy to examine the absorption spectrum and band gap. The detailed examination of the crystal and surface structures was done using X-ray diffraction and field emission scanning electron microscopy (FE-SEM), in order to obtain insight into the structural integrity and the morphology of the titanium oxide nanoparticles. The study provides a deeper insight into TiO2 nano particle production and their characteristics, thereby emphasizing their suitability for advanced material applications.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140998962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Histological manifestations of the Cervix with Chronic Cystic Cervicitis and Nabothian Cyst: Case Report","authors":"Marwa Jamal Hussain, Al Kinani","doi":"10.31185/jwsm.487","DOIUrl":"https://doi.org/10.31185/jwsm.487","url":null,"abstract":" Nabothian cysts are non-malignant lesions that occur on the cervix and affect a large percentage of reproductive aged women. They usually occur because of childbirth or minor trauma; most of the time, they are small and asymptomatic and require no treatment. However, large nabothian cysts may vary in appearance and even resemble malignant tumors. Consequently, in order to rule out malignancy, a biopsy is advised. The greatest valuable imaging modalities for cervical cystic lesions are MRI and transvaginal ultrasonography. Nabothian cysts usually don't need any treatment, but if the lesion's nature is unclear and it hurts, surgery may be necessary. In this case study, chronic pelvic pain is described and abnormal uterine bleeding needed surgical intervention because of chronic cystic cervicitis and multiple nabothian cysts accompanied with Leiomyoma accompanied with adenomyosis and endometrial hyperplasia without atypia.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":"22 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140660986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proposed Development of NTRU Public Key Cryptosystem","authors":"Marwah Aearaby Sayyid","doi":"10.31185/jwsm.485","DOIUrl":"https://doi.org/10.31185/jwsm.485","url":null,"abstract":"As life progresses and develops, cryptography has become an indispensable science. The development of this science has given flexibility and security in exchanging information and data of various kinds by making it difficult for unauthorized persons to access them. In this paper, we proposed a new NTRU-like encryption scheme using a different mathematical structure for the public key, as well as for text encryption and decryption to have more resistance to attacks, which makes this method suitable for many applications.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":"30 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140247658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simulation of Organic Coating Penetration on Metal Using Impedance Spectroscopy","authors":"Ahmed Qasim","doi":"10.31185/jwsm.484","DOIUrl":"https://doi.org/10.31185/jwsm.484","url":null,"abstract":"This paper proposes an alternative model for simulating electrochemical impedance spectra of protective organic coatings on the metal substrate. It describes broadening of the semicircle in the complex plane (Nyquistplot) and Bode plots behavior using commercial software Software ZSimpWin 3.22 in the absence and with of corrosion reactions. Before this process, the appropriate modified electrical equivalent circuit had selected where constant phase element had used instead of a capacitor for reach to reality. The result helps to understand the system under study i.e. the change of impedance behavior with electrochemical processes.","PeriodicalId":513437,"journal":{"name":"Journal of Wasit for Science and Medicine","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140255456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}