Samar H. Kassem, Tarek Aboushousha, Noha H. Ibrahim
{"title":"Prophylactic Effect of Cod Liver Oil on Stone Formation in Rat Kidney: A Novel Approach","authors":"Samar H. Kassem, Tarek Aboushousha, Noha H. Ibrahim","doi":"10.21608/eajbsz.2024.367135","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.367135","url":null,"abstract":"The incidence of kidney stones has increased worldwide in association with economic development; however, treatment modalities are not satisfactory. This study aimed to explore the effect of cod liver oil on the prevention of kidney stone formation in male rats. Renal stones were induced by oral administration of 0.75 % ethylene glycol (EG) with 1% ammonium chloride for 10 days. Twenty-four male rats were separated into 4 groups. Group 1 served as control; group 2 received EG plus NH4CL; group 3 was pre-treated with CLO (480 mg/kg body weight) for 2 weeks, followed by EG plus NH4Cl administration; group 4: was post-treated with CLO plus EG plus NH4Cl. At the end of the experiment, histopathological analysis and the degree of calcification in the renal tissue were analyzed. Blood levels of triglycerides, cholesterol, urea, creatinine, calcium, and phosphorus were determined. Lipid markers, antioxidant markers, and oxidative stress indicators were assessed in renal tissues. EG caused increases in kidney weight, malondialdehyde levels, and the reduction of glutathione, catalase, and SOD in kidney tissues. The results showed a protective effect of CLO against EG-induced nephrolithiasis concomitant with a reduction effect on lipid parameters, amelioration of kidney function markers, and a restoration of antioxidant status. No stone formation was detected in both kidneys, and the amount of calcification was significantly reduced in CLO groups in comparison to the EG group. In conclusion, CLO could be useful in preventing stone formation in rats through modulating lipid profiles and renal membrane lipids and enhancing antioxidant status.","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":" January","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141823604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yousra Ebrahim, Elham Elkhawass, Zohour Nabil, N. El-Shenawy
{"title":"A mini Review of New Potential Therapeutic Strategies Against Trichinellosis","authors":"Yousra Ebrahim, Elham Elkhawass, Zohour Nabil, N. El-Shenawy","doi":"10.21608/eajbsz.2024.353274","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.353274","url":null,"abstract":"Trichinella spiralis is a parasitic nematode transmitted through the consumption of contaminated meat. The study aims to provide comprehensive information on various aspects of","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":" 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140997750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spotted Hyena, Crocuta crocuta (Carnivora: Hyaenidae): an unwelcome visitor to Egypt!","authors":"Aldoushy Mahdy, Samy Saber, Said Elkholy","doi":"10.21608/eajbsz.2024.353067","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.353067","url":null,"abstract":"","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":"48 s166","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modulatory Role of Zeolite against Cadmium Chloride-Induced Renal Damage In Pregnant Rats and Their Fetuses","authors":"Nehad M. Ibrahim, Asmaa Kandil, Rania Ali, Hanan Ahmed, Rania Yahia","doi":"10.21608/eajbsz.2024.352274","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.352274","url":null,"abstract":"Cadmium (Cd) is a heavy metal and a significant inorganic toxin that is commonly found throughout the environment. The human body, as well as the kidneys, tend to accumulate Cd. Research conducted on both humans and animals suggests that exposure to cadmium can lead to significant skeletal damage, specifically osteoporosis. Based on the prevalence of cadmium in the environment and its frequent use, we studied the effect of its toxicity on pregnant rat and their fetuses and the effect of zeolite on them. The experimental rats were divided into 5 groups (n=8, each). The 1 st group received distilled water as a normal control group. The 2 nd received tween 80 and served as tween 80 group. The 3 rd was administrated with zeolite dissolved in tween 80 then in distilled water at a dose (100mgkgday). The 4 th was administrated with cadmium chloride at dose (30mgkgday). The 5 th was administrated with a combination of both zeolite and cadmium chloride. All groups were administered the materials orally from the 6 th day to the 15 th day of gestation. All animals were sacrificed at the end of gestation periods (on the 20 th day). Our obtained results showed adverse histological alterations in maternal and fetal kidneys. Also, CdCl 2 (cadmium chloride) induced remarkable changes in the levels of kidney functions. On the other hand, results showed incomplete ossification of the skull, metacarpals, and phalanges of the toes of fetuses’ skeletons. Zeolite administration markedly ameliorated the altered renal histological and physiological changes as well as the skeletal deformity in fetuses induced by cadmium.","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":"78 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141032439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ellagic Acid Co-Administration: A Protective Strategy Against Aging and Dietary-Induced Pheochromocytoma in Rats","authors":"Gehan Morsy, Bakinam Mohamed, Alyae M. S. Gabal","doi":"10.21608/eajbsz.2024.347035","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.347035","url":null,"abstract":"Benign tumor incidence increased as a result of bad lifestyle and dietary habits. Finding natural dietary antioxidants may help control tumor incidence and spread. Pheochromocytoma is a rare neoplastic chromaffin cell-based benign tumor in the adrenal glands medulla. Pheochromocytoma incidence may increase as a result of the aging process or due to dietary consumption of sugar alcohols. Ellagic acid is a naturally occurring polyphenolic molecule that possesses multiple health benefits and can potentially compete with the development of pheochromocytoma. 50 male Wistar rats were used to investigate the efficacy of ellagic acid in protecting against aging and dietary-induced pheochromocytoma. Biochemical parameters in all experimental rats were determined. Results revealed that both aged and dietary-induced pheochromocytoma caused significant (p≤0.05) boost in systolic blood pressure, catecholamines (dopamine and norepinephrine),metabolites, blood glucose, and serum calcium levels. It also impaired significantly (p≤0.05) renal and hepatic functions, induced oxidative inflammatory status as well as apoptotic gene expression. Ellagic acid consumption protects from pheochromocytoma biochemical alterations and maintains normal body function and hemostasis. Pheochromocytoma is associated with many adverse biochemical changes that may be lethal if it is not diagnosed and treated quickly. Ellagic acid is a promising antioxidant and its consumption can protect from benign tumors. The study is expected to encourage people to change their bad dietary habits and consume natural antioxidants from nature.","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":"121 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghazy A., Abd El-Wahab M., Elmenshawy M., Abdelzaher F.
{"title":"Alleviative Role of Hemin on Reproductive Functions of Adult Male Rats Treated with Copper Oxide Nanoparticles","authors":"Ghazy A., Abd El-Wahab M., Elmenshawy M., Abdelzaher F.","doi":"10.21608/eajbsz.2024.346277","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.346277","url":null,"abstract":"Background: The potential toxicity of copper oxide nanoparticles (CuO NPs), which are frequently employed in a variety of commercial and industrial uses, remains unknown. Hemin is the inducer of heme oxygenase 1, which exerts cytoprotective actions. Objectives : We aimed to assess the potential protective impact of hemin on the sperm of adult rats treated with CuO NPs. Material and methods: 50 adult rats were split into five groups: Group I: control, group II: animals received 40 𝜇 mol/kg b.w./day of solvent, group III: rats received 40 𝜇 mol/kg b.w./day of hemin, group IV: animals received 250 mg/kg b.w./day of CuO NPs and group V: rats received 40 𝜇 mol/kg b.w./day of hemin followed by CuO NPs at a dose of 250 mg /kg b.w./day. Each rat was administered orally as a single dose day after day for 2 weeks. At the completion of the investigation, all rats were sacrificed. Serum sex hormones were quantified and testes homogenized for biochemical analysis. Sperm analysis was processed for light microscopic examination. Results: Nanocopper reduces fertility hormone levels leading to sperm toxicity. CuO NPs also significantly decreased the activities of antioxidant enzymes accompanied by significant elevation in the MDA levels in testes in contrast to the control group. Hemin treatment reduced the majority of the toxic impacts of CuO NPs via their antioxidative capacity. Conclusion: Administration of hemin ameliorated sex hormones, oxidative stress, lipid peroxidation and sperm characteristics in CuO NPs intoxicated rats.","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140387045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heba Ismail, A.A.A. Saleh, M. M. A. Hafez, Rehab M. El-Gendy
{"title":"Estimating Seasonal Abundance of Piercing-Sucking Insects and Their Natural Enemies on Sweet Basil Plants","authors":"Heba Ismail, A.A.A. Saleh, M. M. A. Hafez, Rehab M. El-Gendy","doi":"10.21608/eajbsz.2024.345955","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.345955","url":null,"abstract":"Piercing-sucking insects are notorious devastating insects that cause substantial damage to crops and yield losses due to the direct feeding by both nymphs and adults furthermore through the transmission of viruses and diseases. Field experiments were conducted during the two growing summer seasons of 2021 and 2022 at Zagazig district, Sharkia Governorate, Egypt to assess the seasonal abundance of the major piercing-sucking insects and their associated natural enemies on sweet basil plants. Five piercing-sucking insect species were surveyed; Bemisia tabaci (Genn.), Aphis gossypii Glover, Nezara viridula L., Empoasca decipiens (Paoli), and Thrips tabaci Lind. Also, six predatory species were recorded; Coccinella undecimpunctata L., Chrysoperla carnea (Steph.), Orius sp., Paederus alfierii (Koch), Metasyrphus corollae (Fabr.) and Scymnus sp., and three parasitoid species were observed; Aphidius colemani (Viereck) as a primary parasitoid, Alloxysta sp. as a hyperparasitoid on A . gossypii and Trissolcus megalocephalus (Ashmead) as a parasitoid of N . viridula eggs. Our observations about the main piercing-insects and their natural enemies on sweet basil could be considered as a part of their control plan.","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":" 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140388483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ameliorative Effect of Cinnamon against Hypercholesterolemia Induced by High-Fat Diet in The Adult Male Albino Rat's Adrenal Gland; Histological, Ultrastructural, and Immunohistochemical Studies","authors":"Eman H. Kandil, Samah M. Arisha, M. Saif","doi":"10.21608/eajbsz.2024.344611","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.344611","url":null,"abstract":"Obesity is a global health issue of great concern. It leads to hyperplasia, hypertrophy of adipocytes, and metabolic complications including coronary artery disease, and cerebrovascular disease. The effectiveness of cinnamon zeylanicum as a medicinal herb comes from its anti-inflammatory and antioxidant properties. The purpose of this study was to assess the potential beneficial effects of cinnamon on adrenal toxicity caused by a high-fat diet in male albino rats. Four equal groups of the experimental animals were used, the control group, the cinnamon group, the high-fat diet group, the high-fat diet, and the cinnamon group. Animals fed cinnamon showed similar results with the control group. The adrenal cortex sections of high-fat diet-fed animals showed different degenerative changes in all layers of the adrenal gland, cortex, medulla, and corrugation of the capsule. Ultra structurally, a lot of adrenal cortical cells appeared with irregular pyknotic nuclei, swollen mitochondria, dilated sER, and numerous lipid droplets with variable shapes and sizes. Moreover, a significant rise in the immunohistochemical expression of cytochrome c in a large number of cortical cells was observed. On the contrary, animals given cinnamon and a high-fat diet exhibited noticeable improvement in the structure of the adrenal gland, and the immunohistochemical expression of cytochrome c was observed in the third group. The histological structure of the adrenal gland appeared to be mostly the same as the control one. Cinnamon has a potential effect in improving adrenal toxicity against a high-fat diet because of the natural constituent capable of its pharmaceutical effects.","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":"58 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140255628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of l-carnitine Nanoparticles against Nephrotoxicity Induced by 5-Fluorouracil in Ehrlich ascites Carcinoma Bearing Mice","authors":"Heba Elsayed, Asmaa Zaazaa, Fatma Fouda*","doi":"10.21608/eajbsz.2024.340550","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.340550","url":null,"abstract":"","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":"32 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of l-carnitine Nanoparticles against Nephrotoxicity Induced by 5-Fluorouracil in Ehrlich ascites Carcinoma Bearing Mice","authors":"Heba Elsayed, Asmaa Zaazaa, Fatma Fouda*","doi":"10.21608/eajbsz.2024.340550","DOIUrl":"https://doi.org/10.21608/eajbsz.2024.340550","url":null,"abstract":"","PeriodicalId":513213,"journal":{"name":"Egyptian Academic Journal of Biological Sciences, B. Zoology","volume":"181 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139841849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}