International Journal of Medical and Surgical Sciences最新文献

Pediatric Patients with Acute Lymphoblastic Leukemia in Honduras: Demographic Characteristics, Clinical Features, and Laboratory Findings 洪都拉斯急性淋巴细胞白血病儿科患者：人口统计学特征、临床特征和实验室结果

International Journal of Medical and Surgical Sciences Pub Date : 2024-07-22 DOI: 10.32457/ijmss.v11i2.2585

Isabel Ramos, Andrea María Sierra Barahona, Sarah Angelly Membreño Soto, Andrea Jacqueline Inés Rodas Figueroa, Clarissa Lizeth Aguilar Molina

{"title":"Pediatric Patients with Acute Lymphoblastic Leukemia in Honduras: Demographic Characteristics, Clinical Features, and Laboratory Findings","authors":"Isabel Ramos, Andrea María Sierra Barahona, Sarah Angelly Membreño Soto, Andrea Jacqueline Inés Rodas Figueroa, Clarissa Lizeth Aguilar Molina","doi":"10.32457/ijmss.v11i2.2585","DOIUrl":"https://doi.org/10.32457/ijmss.v11i2.2585","url":null,"abstract":"Approximately 90% of confirmed cancer cases annually are reported in low to middleincome countries. In Honduras, the incidence of pediatric cancer has been steadily increasing, accompanied by a higher cancer mortality rate attributed to diagnostic errors, limited access to healthcare, and management challenges. Diagnostic pitfalls, such as failure to recognize signs of malignancy, inadequate assessment of persistent symptoms, and misinterpretation of diagnostic tests, significantly impede effective cancer care. This retrospective case study collected data from 68 pediatric patients diagnosed with Acute Lymphoblastic Leukemia (ALL) at the Honduran Social Security Institute in Tegucigalpa between January 2015 and December 2022. Data retrieval encompassed demographic features, clinical characteristics, and laboratory findings. We used SPSS Statistics version 29.0.2.0 to perform all statistical analysis. The cohort comprised patients of equal gender distribution, with 42.6% (N: 29) belonging to the age group of 1 to 4 years. The hospital diagnosed an average of 8.5 cases each year. Fever was the most prevalent symptom, affecting 80.9% of patients (N: 55). Hemoglobin levels were below 10 mg/dL in 67.6% of patients, with 33.8% exhibiting levels below 7 mg/dL (N: 23) and equal proportion falling within the 7-10 mg/dL range (N: 23). Platelet levels were below 150,000/μL, with 48.5% experiencing severe thrombocytopenia (platelet levels <50,000/μL). Additionally, most patients presented phosphorus levels exceeding 4.5 mg/dl (N: 33, 48.5%), along with elevated LDH levels surpassing 500 U/l (N: 34, P: 50%). The presence of persistent fever should trigger suspicion of cancer, necessitating thorough assessment. Implementing guidelines outlining common symptoms and referral protocols could significantly reduce mortality in Honduran children with ALL.","PeriodicalId":512955,"journal":{"name":"International Journal of Medical and Surgical Sciences","volume":"20 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141814703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective Effects of Tigernut (Cyperus esculentus) on Bisphenol A- Induced Testicular Toxicity in Wistar Rats 虎耳草（Cyperus esculentus）对双酚 A 诱导的 Wistar 大鼠睾丸毒性的保护作用

International Journal of Medical and Surgical Sciences Pub Date : 2024-07-22 DOI: 10.32457/ijmss.v11i2.2588

Abraham Abigail, Idaguko Chika Anna

{"title":"Protective Effects of Tigernut (Cyperus esculentus) on Bisphenol A- Induced Testicular Toxicity in Wistar Rats","authors":"Abraham Abigail, Idaguko Chika Anna","doi":"10.32457/ijmss.v11i2.2588","DOIUrl":"https://doi.org/10.32457/ijmss.v11i2.2588","url":null,"abstract":"Bisphenol A (BPA) have been reported to induced reprotoxicity in rats. This study was conducted to find out the ameliorative properties of aqueous extract of Cyperus esculentus (tigernut) on BPA induced testicular toxicity in Wistar rats.\u0000Methods: Twenty male rats were divided randomly into 4 groups (n=5): group A: (Control); group B: Bisphenol A (BPA) (25 mg/kg b.w/day); group C: tigernut (200 mg/kg b.w); group D: (25 mg/kg of BPA+ 200 mg/kg of tigernut extract. 25 mg/kg of BPA was dissolved in 0.2 ml of olive oil as vehicle and administration was given by oral gavage for 4 weeks. The body weights were measured. Blood were collected for the testosterone (T) and luteinizing hormone (LH) assays; the epididymis were processed for sperm count, sperm motility, sperm viability and sperm abnormality test; while the testes were harvested for histology.\u0000Results: There was a significantly (p < 0.05) decreased in body weight; reduced (sperm count, motility, viability, serum testosterone and luteinizing hormone) in BPA compared with control group. These parameters however increased significantly (p < 0.05) in tigernut (200mg) and BPA + tigernut (200mg) compared with BPA. Also, histological examination showed widened interstitial spaces, some distorted seminiferous tubules, degeneration of basement membrane, scanty Leydig cells, fewer spermatozoa and vacuolation While BPA + tigernut (group D); showed improved testicular architecture (preserved interstitial spaces and interstitial cells. restoration of the loss of the basement membrane and closely packed seminiferous tubules with well-arranged germinal epithelium. Supplementation with tigernuts following BPA administration produces a reversal of the deleterious effect of BPA on the testis.","PeriodicalId":512955,"journal":{"name":"International Journal of Medical and Surgical Sciences","volume":"13 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141816144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Reports on Anatomical Variations of the Hepatic Arteries: Implications for Laparoscopic Cholecystectomy and Surgical Safety 肝动脉解剖变异病例报告：对腹腔镜胆囊切除术和手术安全性的影响

International Journal of Medical and Surgical Sciences Pub Date : 2024-07-02 DOI: 10.32457/ijmss.v11i2.2498

Oscar Alonso Plaza-Patino, Luis Felipe Dorado-Ramírez, Yolibeth Rodríguez-Morales, Juan Pablo Zambrano-Zorrilla

{"title":"Case Reports on Anatomical Variations of the Hepatic Arteries: Implications for Laparoscopic Cholecystectomy and Surgical Safety","authors":"Oscar Alonso Plaza-Patino, Luis Felipe Dorado-Ramírez, Yolibeth Rodríguez-Morales, Juan Pablo Zambrano-Zorrilla","doi":"10.32457/ijmss.v11i2.2498","DOIUrl":"https://doi.org/10.32457/ijmss.v11i2.2498","url":null,"abstract":"A laparoscopic surgeon’s understanding of embryology, anatomy, and potential anatomical variations of the bile duct is crucial for safely performing gallbladder removal using this minimally invasive technique. In conducting two medical-legal autopsies, we identified a previously undocumented anatomical variant where the liver’s blood supply originates from the common hepatic artery, branching into a trident formation to form the right, left, and cystic hepatic arteries. Notably, the right hepatic artery is situated within Calot’s triangle, whereas the cystic artery is located anomalously outside the triangle. This anatomical anomaly poses significant surgical risks, including the potential for morbidity and mortality due to ischemic necrosis of the liver from vascular injury. The success of laparoscopic surgery under these circumstances relies heavily on the surgeon’s expertise in managing an atypical surgical field, adherence to a culture of safety, and a critical approach to safety in laparoscopic cholecystectomy.","PeriodicalId":512955,"journal":{"name":"International Journal of Medical and Surgical Sciences","volume":"31 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vol. 11 No. 2 (2024): June, 2024 第 11 卷第 2 期（2024 年）：2024 年 6 月

International Journal of Medical and Surgical Sciences Pub Date : 2024-07-02 DOI: 10.32457/ijmss.v11i2

引用次数: 0

Giant Solitary Pulmonary Fibrous Tumor: Case Report 巨大单发肺纤维瘤：病例报告

International Journal of Medical and Surgical Sciences Pub Date : 2024-07-01 DOI: 10.32457/ijmss.v11i2.2493

Jesús Nicolás Larco Coloma, Marco Valenzuela Cifuentes, Milton Araujo Parra, Nathalie Estephania Pungacho Espin, Patricio Bucheli Proaño, Byron Salgado, Nicolás Larco Noboa

引用次数: 0

Sphenoid intraosseous meningioma associated with monostotic hyperostosis “a diagnostic challenge”: case report 蝶骨骨内脑膜瘤伴单侧骨质增生 "诊断难题"：病例报告

International Journal of Medical and Surgical Sciences Pub Date : 2024-04-22 DOI: 10.32457/ijmss.v11i1.2434

J. Serna-Trejos, Stefanya Geraldine Bermúdez–Moyano, María Elena Candia-Garzón, Juan Pablo Lenis-González, Wendy Tatiana Ibarguen-Gómez, Mónica Lucía Vergara-Portocarrero

引用次数: 0

Evaluation of wheat (Triticum aestivium L) diet on reproductive functions of adult female rats 小麦（Triticum aestivium L）饮食对成年雌性大鼠生殖功能的评估

International Journal of Medical and Surgical Sciences Pub Date : 2024-04-10 DOI: 10.32457/ijmss.v11i1.2446

C. A. Idaguko, Gladys Agoreyo

{"title":"Evaluation of wheat (Triticum aestivium L) diet on reproductive functions of adult female rats","authors":"C. A. Idaguko, Gladys Agoreyo","doi":"10.32457/ijmss.v11i1.2446","DOIUrl":"https://doi.org/10.32457/ijmss.v11i1.2446","url":null,"abstract":"Introduction: The relationships between wheat diet, sex hormone and the estrous cycle are important from the perspective of fertility. Aim: This study aims to investigate the effect of wheat diet on weight, estrous cycle, reproductive hormones and histology of the ovary of female Sprague-Dawley rats. Methods: Prior to the test, vaginal smear was monitored daily for 16 days period to select females with normal (regular) estrous cycle. A total of twenty rats with regular estrous cycle weighing between 170-200 g were randomized into four sets of 5 animals each. Group A is the female control and was fed with rat chow, group B, C and D was given 40%, 60%, 100% of wheat diet respectively. The wheat diet was giving respectively for a period of 4 weeks. Estrous cycle pattern was monitored using the vaginal smear for 16 days. At the end of the experiment, the rats were sacrificed and the blood sample were taken for follicle stimulating hormone, luteinizing hormones, estradiol, and progesterone analysis. The histology of the ovary were carried out. Results: The result showed that there was an increase in the weight of the rats that was fed with wheat and the increase was diet dependent. The wheat diets disrupt the order of appearance of normal estrous cycle stages, hence; there was no constancy in the frequency of all cycle stages in the wheat groups, mostly the 100% wheat group. No significant endocrine or histological differences noticed between control and wheat diets groups. Therefore photomicrograph of wheat diet shows large corpus luteum, thick germinal epithelium, zona granulosa and oocyte. Conclusion: Wheat diets disrupt the estrous cycle of the rats; however no adverse effect was noticed on the circulating reproductive hormones and histology of the ovary. However, high consumption of wheat should be taken with precaution.","PeriodicalId":512955,"journal":{"name":"International Journal of Medical and Surgical Sciences","volume":"53 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140720305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telemedicine from the perspective of health personnel in a public hospital in Paraguay, 2023Telemedicine from the perspective of health personnel in a public hospital in Paraguay, 2023 从巴拉圭一家公立医院医务人员的角度看远程医疗，2023年从巴拉圭一家公立医院医务人员的角度看远程医疗，2023年

International Journal of Medical and Surgical Sciences Pub Date : 2024-04-01 DOI: 10.32457/ijmss.v11i1.2421

Chap Kau Kwan Chung, Rafael Riquelme Benítez

引用次数: 0

Vol. 11 No. 1 (2024): March, 2024 第 11 卷第 1 期（2024 年）：2024 年 3 月

International Journal of Medical and Surgical Sciences Pub Date : 2024-04-01 DOI: 10.32457/ijmss.v11i1

引用次数: 0

Global overview of monkeypox: An epidemiological and clinical update 全球猴痘概况：流行病学和临床最新进展

International Journal of Medical and Surgical Sciences Pub Date : 2024-04-01 DOI: 10.32457/ijmss.v11i1.2369

D. Prado-Molina, J. S. Serna Trejos, Stefanya Geraldine Bermúdez–Moyano, J. Rojas-Hernández

{"title":"Global overview of monkeypox: An epidemiological and clinical update","authors":"D. Prado-Molina, J. S. Serna Trejos, Stefanya Geraldine Bermúdez–Moyano, J. Rojas-Hernández","doi":"10.32457/ijmss.v11i1.2369","DOIUrl":"https://doi.org/10.32457/ijmss.v11i1.2369","url":null,"abstract":"Mpox (viruela símica) es una enfermedad viral que puede producir síntomas como erupción cutánea, adenomegalias y fiebre. Pese a su baja tasa de mortalidad, se relaciona con complicaciones que pueden comprometer la calidad de vida de las personas. Fue identificada por primera vez en humanos en 1970, desde entonces se mantenía una distribución geográfica y una incidencia controladas. No obstante, desde el año 2022 su incidencia ha aumentado al igual que su distribución geográfica alcanzando un total de 89.596 casos confirmados por laboratorio y 663 casos probables, incluidas 157 muertes, reportados al 28 de agosto de 2023; llegando incluso a países no endémicos. A continuación, se presenta una revisión narrativa con base en información recolectada en bases de datos como UpToDate, Google Scholar, Medline, ClinicalKey, Scopus, Embase, Pubmed; con el objetivo de describir los aspectos más relevantes de Mpox en humanos desde una perspectiva epidemiológica actual, además de presentar datos fisiopatológicos, de diagnóstico, tratamiento, pronóstico y rehabilitación.","PeriodicalId":512955,"journal":{"name":"International Journal of Medical and Surgical Sciences","volume":"42 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140796363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0