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引用次数: 0
摘要
巨型肺单发纤维瘤是一种罕见的纤维母细胞分化的间质肿瘤,好发于胸腔内和口内。与特定的危险因素无关。临床表现无特异性,生长缓慢。本病例是一名 54 岁的患者,中度用力时出现呼吸困难,并伴有消失的左肺泡杂音。他患上了难治性低血糖症,导致 Doege Potter 综合征。计算机轴向断层扫描显示左胸部有一个全占位性肿块。为了更好地暴露肿瘤和控制血流动力学,他采用了胸骨加左胸廓切开术的改良方法,以探查肿瘤的营养血管并全切肿瘤。组织病理学显示,该肿瘤在医学文献中被报道为较重的肿瘤。显微镜下可见由纺锤形和卵圆形细胞组成的间质瘤,巨型单发肺纤维瘤免疫组化阳性。
Giant Solitary Pulmonary Fibrous Tumor: Case Report
The giant pulmonary solitary fibrous tumor is a mesenchymal tumor of rare fibroblastic differentiation, preferably intrathoracic and intraoral. Not associated with specific risk factors. Non-specific clinical presentation and slow growth. The present case is of a 54-year-old patient with dyspnea on medium exertion with the presence of abolished left vesicular murmur. He developed refractory hypoglycemia leading to Doege Potter syndrome. A total occupying mass was evident in the left chest on computed axial tomography. A modified approach was performed by sternotomy plus left thoracotomy to improve exposure and hemodynamic control with access to the tumor’s nutritional vessels and total tumor excision. Histopathology revealed a heavier tumor reported in the medical literature. Microscopy presence of mesenchymal neoplasia composed of spindle-shaped and oval cells and positive immunohistochemistry of giant solitary pulmonary fibroma.