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Hepatitis C and interferon-associated retinopathy: A case report 丙型肝炎和干扰素相关视网膜病变1例报告
Optometry Pub Date : 2011-12-01 DOI: 10.1016/j.optm.2010.11.016
Ann M. Van Wie O.D.
{"title":"Hepatitis C and interferon-associated retinopathy: A case report","authors":"Ann M. Van Wie O.D.","doi":"10.1016/j.optm.2010.11.016","DOIUrl":"10.1016/j.optm.2010.11.016","url":null,"abstract":"<div><h3>Background</h3><p><span><span><span><span>Hepatitis C is a common virus affecting approximately 170 million people worldwide. The main ocular manifestations of </span>hepatitis C virus include a Sjögren-type of dry eye syndrome and an ischemic </span>retinopathy<span> secondary to treatment with </span></span>interferon<span> or a result of a systemic vasculitis induced by the infection itself. Current treatment for hepatitis C is a combination therapy using pegylated (long-lasting) interferon and </span></span>ribavirin<span><span>. This treatment, however, is not without ocular sequelae. Interferon-associated retinopathy is present in &gt; 50% of patients taking the </span>drug<span><span> and is mainly characterized by cotton wool spots and </span>retinal hemorrhages. The pathogenesis of this disorder is not specifically known. Fortunately, many patients remain asymptomatic, and the retinal changes are usually reversible.</span></span></p></div><div><h3>Case Report</h3><p>A 48-year-old black man presented to the clinic complaining of decreased vision in both eyes for the previous few weeks. His medical history was positive for hypertension and hepatitis C for which he was being treated. At his examination, he had interferon retinopathy diagnosed. Soon thereafter, his treatment for hepatitis C was discontinued, and when he returned for follow-up 4 months later, his retinal findings had resolved.</p></div><div><h3>Conclusions</h3><p>An overview of hepatitis C and its recommended therapy and possible ocular side effects are reviewed, as well as the differential diagnosis of interferon-associated retinopathy, 1 of the main side effects of treatment.</p></div>","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"82 12","pages":"Pages 739-743"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.optm.2010.11.016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30276099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Guidelines for Authors 作者指南
Optometry Pub Date : 2011-12-01 DOI: 10.1016/S1529-1839(11)00555-0
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引用次数: 0
Toric soft contact lens fit in a postoperative LASIK keratoectasia patient with high and irregular astigmatism 环形软性接触镜适合于高度不规则散光的LASIK角膜扩张术后患者
Optometry Pub Date : 2011-12-01 DOI: 10.1016/j.optm.2011.06.011
David P. Roncone O.D.
{"title":"Toric soft contact lens fit in a postoperative LASIK keratoectasia patient with high and irregular astigmatism","authors":"David P. Roncone O.D.","doi":"10.1016/j.optm.2011.06.011","DOIUrl":"10.1016/j.optm.2011.06.011","url":null,"abstract":"<div><h3>Background</h3><p><span>Keratoectasia is a rare but well-known complication after laser-assisted in situ keratomileusis (LASIK). Patients with this condition can have high and irregular astigmatism. When the </span>treatment<span> of the high astigmatic correction cannot be accomplished surgically or when the keratoectasia patient rejects surgical enhancement, optical correction with devices such as soft or rigid gas-permeable contact lenses may be pursued. In fact, toric soft contact lenses are a good first option for fitting postoperative keratoectasia patients.</span></p></div><div><h3>Case report</h3><p><span><span>A 58-year-old white male presented for an examination with a complaint of decreased distance vision in the right eye (OD) after having traditional LASIK for myopia with astigmatism in both eyes (OU) in 1999 and limbal relaxing incision enhancement OD in 2003. Refraction showed high mixed astigmatism OD (+1.75 -5.75×075). </span>Slit lamp examination found irregularity of the cornea, evidenced by an inferior cone with pigmented Fleischer ring OD. Video </span>keratometry<span> had keratometry readings of 43.50 at 160, 39.87 at 070, elevated shape measure (0.40), elevated corneal irregularity measure (3.96), an inferior cone on the elevation map, and asymmetric bowtie with elongation inferonasally on the axial map, which confirmed the diagnosis of postoperative keratoectasia. Because new surgical treatments at that time for corneal ectasia<span> were in their infancy and not approved by the U.S. Food and Drug Administration, the patient opted for a trial toric soft contact lens fitting, which improved his corrected distance visual acuity to 20/25.</span></span></p></div><div><h3>Conclusion</h3><p>This case report confirms that toric soft contact lenses are a good first choice in fitting patients with high and irregular astigmatism from postoperative LASIK corneal ectasia. It also confirms that excellent vision and comfort with toric soft contact lenses is possible in these patients.</p></div>","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"82 12","pages":"Pages 751-756"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.optm.2011.06.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30081841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Vision Rehabilitation: Multidisciplinary Care of the Patient Following Brain Injury 视力康复:脑损伤后患者的多学科护理
Optometry Pub Date : 2011-12-01 DOI: 10.1016/j.optm.2011.10.009
Leonard J. Press O.D.
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引用次数: 46
Optometry Referees 2010-2011 2010-2011验光裁判
Optometry Pub Date : 2011-12-01 DOI: 10.1016/S1529-1839(11)00561-6
{"title":"Optometry Referees 2010-2011","authors":"","doi":"10.1016/S1529-1839(11)00561-6","DOIUrl":"https://doi.org/10.1016/S1529-1839(11)00561-6","url":null,"abstract":"","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"82 12","pages":"Pages 786-787"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1529-1839(11)00561-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136615453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipemia retinalis: a combination of genetics and the American diet and lifestyle. 视网膜脂血症:基因与美国饮食和生活方式的结合。
Optometry Pub Date : 2011-11-03 DOI: 10.1016/J.OPTM.2011.05.008
Samantha L C Nogales, A. Grimes, Huey-Fen Song
{"title":"Lipemia retinalis: a combination of genetics and the American diet and lifestyle.","authors":"Samantha L C Nogales, A. Grimes, Huey-Fen Song","doi":"10.1016/J.OPTM.2011.05.008","DOIUrl":"https://doi.org/10.1016/J.OPTM.2011.05.008","url":null,"abstract":"","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"19 1","pages":"107-10"},"PeriodicalIF":0.0,"publicationDate":"2011-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81423721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Interactions of visual and cognitive stress 视觉和认知压力的相互作用
Optometry Pub Date : 2011-11-01 DOI: 10.1016/j.optm.2011.07.003
Niru K. Nahar Ph.D. , Sowjanya Gowrisankaran Ph.D. , John R. Hayes Ph.D. , James E. Sheedy O.D., Ph.D.
{"title":"Interactions of visual and cognitive stress","authors":"Niru K. Nahar Ph.D. ,&nbsp;Sowjanya Gowrisankaran Ph.D. ,&nbsp;John R. Hayes Ph.D. ,&nbsp;James E. Sheedy O.D., Ph.D.","doi":"10.1016/j.optm.2011.07.003","DOIUrl":"10.1016/j.optm.2011.07.003","url":null,"abstract":"<div><h3>Background</h3><p>The objective of this research is to assess the ocular and muscular response to long-duration reading under different visual and cognitive difficulty levels.</p></div><div><h3>Methods</h3><p><span><span>Thirty-five subjects, with 20/20 vision and without history of ocular pathology or </span>cognitive deficits, participated in the study. Subjects read under different visual and cognitive difficulty levels for 6 (30-minute) conditions. Upper and lower orbicularis oculi, frontalis, and </span>trapezius muscle<span><span> activities were recorded using surface electromyography (EMG). Aperture size, pupil diameter, and pulse rate of the subjects were recorded with a video camera, pulse meter, and ISCAN </span>eye tracker (ISCAN Inc.), respectively.</span></p></div><div><h3>Results</h3><p><span>The results show that the texts read with a refractive error caused increased orbicularis oculi EMG power and reduced aperture size (</span><em>P</em> &lt; 0.001). There was no statistically significant difference between the conditions for pulse rate, pupil diameter, or EMG activity of the frontalis and trapezius muscles with either visual or cognitive stress presented in this experiment.</p></div><div><h3>Conclusion</h3><p>Visual stress experienced due to reading under an induced refractive error is potentially mediated by a local mechanism, different from the mechanism underlying reading under low contrast or high cognitive demand.</p></div>","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"82 11","pages":"Pages 689-696"},"PeriodicalIF":0.0,"publicationDate":"2011-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.optm.2011.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30115783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration 萎缩性年龄相关性黄斑变性患者玉米黄质与视觉功能的随机、双盲、安慰剂对照研究
Optometry Pub Date : 2011-11-01 DOI: 10.1016/j.optm.2011.08.008
Stuart P. Richer O.D., Ph.D. , William Stiles M.D., J.D. , Kelly Graham-Hoffman PsyD , Marc Levin M.D., J.D. , Dennis Ruskin O.D. , James Wrobel DPM , Dong-Wouk Park , Carla Thomas
{"title":"Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration","authors":"Stuart P. Richer O.D., Ph.D. ,&nbsp;William Stiles M.D., J.D. ,&nbsp;Kelly Graham-Hoffman PsyD ,&nbsp;Marc Levin M.D., J.D. ,&nbsp;Dennis Ruskin O.D. ,&nbsp;James Wrobel DPM ,&nbsp;Dong-Wouk Park ,&nbsp;Carla Thomas","doi":"10.1016/j.optm.2011.08.008","DOIUrl":"10.1016/j.optm.2011.08.008","url":null,"abstract":"<div><h3>Background</h3><p>The purpose of this study is to evaluate whether dietary supplementation<span> with the carotenoid<span> zeaxanthin<span> (Zx) raises macula pigment optical density<span> (MPOD) and has unique visual benefits for patients with early atrophic macular degeneration having visual symptoms but lower-risk National Institute of Health/National Eye Institute/Age-Related Eye Disease Study characteristics.</span></span></span></span></p></div><div><h3>Methods</h3><p><span><span>This was a 1-year, n = 60 (57 men, 3 women), 4-visit, intention-to-treat, prospective, randomized controlled clinical trial of patients (74.9 years, standard deviation [SD] 10) with mild-to-moderate age-related macular degeneration (AMD) randomly assigned to 1 of 2 dietary supplement carotenoid pigment intervention groups: 8 mg Zx (n = 25) and 8 mg Zx plus 9 mg </span>lutein<span> (L) (n = 25) or 9 mg L (“Faux Placebo,” control group, n = 10). Analysis was by Bartlett’s test for equal variance, 3-way repeated factors analysis of variance, independent </span></span><em>t</em> test (<em>P</em><span><span> &lt; 0.05) for variance and between/within group differences, and post-hoc Scheffé's tests. Estimated foveal heterochromic flicker photometry, 1° </span>macular pigment optical density (MPOD QuantifEye</span><sup>®</sup><span><span>), low- and high-contrast visual acuity, foveal shape discrimination (Retina Foundation of the Southwest), 10° yellow kinetic visual fields (KVF), glare recovery, </span>contrast sensitivity function (CSF), and 6° blue cone ChromaTest</span><sup>®</sup> color thresholds were obtained serially at 4, 8, and 12 months.</p></div><div><h3>Results</h3><p><span><span>Ninety percent of subjects completed ≥ 2 visits with an initial Age-Related Eye Disease Study report #18 retinopathy score of 1.4 (1.0 SD)/4.0 and pill intake compliance of 96% with no adverse effects. There were no intergroup differences in 3 major AMD risk factors: age, smoking, and </span>body mass index<span> as well as disease duration and Visual Function Questionnaire 25 composite score differences. Randomization resulted in equal MPOD variance and MPOD increasing in each of the 3 groups from 0.33 density units (du) (0.17 SD) baseline to 0.51 du (0.18 SD) at 12 m, (</span></span><em>P</em> = 0.03), but no between-group differences (Analysis of Variance; <em>P</em> = 0.47). In the Zx group, detailed high-contrast visual acuity improved by 1.5 lines, Retina Foundation of the Southwest shape discrimination sharpened from 0.97 to 0.57 (<em>P</em><span> = 0.06, 1-tail), and a larger percentage of Zx patients experienced clearing of their KVF central scotomas (</span><em>P</em> = 0.057). The “Faux Placebo” L group was superior in terms of low-contrast visual acuity, CSF, and glare recovery, whereas Zx showed a trend toward significance.</p></div><div><h3>Conclusion</h3><p>In older male patients with AMD, Zx-induced foveal MPOD elevation mirrored that of L and provided compl","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"82 11","pages":"Pages 667-680.e6"},"PeriodicalIF":0.0,"publicationDate":"2011-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.optm.2011.08.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30231850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 102
Updating the practice for the better 为了更好地更新实践
Optometry Pub Date : 2011-11-01 DOI: 10.1016/j.optm.2011.09.006
Gary Gerber O.D.
{"title":"Updating the practice for the better","authors":"Gary Gerber O.D.","doi":"10.1016/j.optm.2011.09.006","DOIUrl":"10.1016/j.optm.2011.09.006","url":null,"abstract":"","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"82 11","pages":"Page 717"},"PeriodicalIF":0.0,"publicationDate":"2011-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.optm.2011.09.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78041117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microtropia: clinical findings and management for the primary eye care practitioner 斜视:初级眼保健医生的临床表现和管理
Optometry Pub Date : 2011-11-01 DOI: 10.1016/j.optm.2011.02.020
Josephine O. Ibironke O.D., MPH
{"title":"Microtropia: clinical findings and management for the primary eye care practitioner","authors":"Josephine O. Ibironke O.D., MPH","doi":"10.1016/j.optm.2011.02.020","DOIUrl":"10.1016/j.optm.2011.02.020","url":null,"abstract":"<div><h3>Background</h3><p>Microtropia is a small-angle strabismus with a highly developed degree of binocular cooperation. It is a unilateral comitant horizontal deviation less than 5 prism diopters (PD) in the presence of anomalous retinal correspondence (ARC), amblyopia, some motor fusion, and reduced stereoacuity.</p></div><div><h3>Case report</h3><p>A 7-year-old white girl presented for a second opinion concerning unexplained vision loss<span><span> in the left eye. Visual acuities were 20/20 in the right eye and 20/200 in the left eye. Ocular evaluation found normal eye health with a 4-PD constant left </span>esotropia at near and a 3-PD constant left esotropia at distance on unilateral cover test. A diagnosis of steady nasal eccentric fixation microtropia without identity with strabismic amblyopia in the left eye was made. Over the follow-up period, visual acuity improved but the alignment did not.</span></p></div><div><h3>Conclusion</h3><p>Microtropia can defy detection, resulting in a reduced chance of achieving near-normal visual potential in children. It is important for clinicians to understand the possible etiologies, related entities, proper testing, differential diagnoses, and the goals of treatment. This case report reviews the clinical findings, diagnoses, and management of patients with microtropia.</p></div>","PeriodicalId":51265,"journal":{"name":"Optometry","volume":"82 11","pages":"Pages 657-661"},"PeriodicalIF":0.0,"publicationDate":"2011-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.optm.2011.02.020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30134084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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