Neurochirurgie最新文献

{"title":"The neurosurgeon as athlete, gentleman, and physician: Thierry de Martel (1875–1940) as a model for contemporary practice","authors":"Johan Pallud","doi":"10.1016/j.neuchi.2026.101772","DOIUrl":"10.1016/j.neuchi.2026.101772","url":null,"abstract":"","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101772"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145981247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyethylene glycol-coated patch versus standard dural sealing practices for preventing cerebrospinal fluid leaks in posterior fossa surgery: a randomized multicenter study","authors":"Alberto Acitores Cancela ,&nbsp;María Pérez Pérez ,&nbsp;Luis González Martínez ,&nbsp;Jorge Díaz Molina ,&nbsp;Laura Beatriz López López ,&nbsp;Sofía Sotos Picazo ,&nbsp;Carmen Tudela Ataz ,&nbsp;Cristina Barcelo López ,&nbsp;Juan Carlos Rial Básalo ,&nbsp;Cristina Ferreras ,&nbsp;Belén Álvarez ,&nbsp;Adán Fernández Canal ,&nbsp;Jose Manuel Ortega ,&nbsp;Jorge Bernal Piñeiro ,&nbsp;Yaiza López Ramírez ,&nbsp;Carlos Alberto Rodríguez Arias ,&nbsp;Rubén Martín Laez ,&nbsp;Patricia López Gómez ,&nbsp;Luís Ley-Urzaiz","doi":"10.1016/j.neuchi.2026.101777","DOIUrl":"10.1016/j.neuchi.2026.101777","url":null,"abstract":"<div><h3>Background</h3><div>This study evaluated the efficacy and safety of the polyethylene glycol (PEG)-coated patch as a dural sealant in elective non-traumatic posterior fossa surgeries (nTPFS) requiring dural closure.</div></div><div><h3>Methods</h3><div>This multicenter, randomized, controlled phase-IV study was conducted, between January and December 2022, on adult patients who underwent nTPFS requiring dural opening and closure. Patients were randomized to receive either PEG-coated patch reinforcement or standard sealing. The primary endpoint was the incidence of clinically evident cerebrospinal fluid (CSF)-leakage within four weeks post-intervention.</div></div><div><h3>Results</h3><div>A total of 121 patients were included, 57(47.1%) in the PEG-coated patch group and 64(52.9%) in the standard sealing group. No statistically significant differences were observed in the primary endpoint of clinically evident CSF leak (12.3% vs. 9.4%; incidence rate difference: 2.9%; 95%CI: –8.7% to 14.6%; p = 0.606). Secondary outcomes were also comparable between groups, including pseudomeningocele (24.6% vs. 20.3%; p = 0.575), hospital readmissions (12.3% vs. 9.4%; p = 0.606), surgical site infections (5.3% vs. 4.7%; p = 0.884), and adverse events (22.8% vs. 20.3%; p = 0.739). Two patients, one in each group, experienced serious adverse events classified as “hospitalization or prolonged stay.” Most adverse events were mild to moderate and resolved with standard medical management.</div></div><div><h3>Conclusions</h3><div>The PEG-coated patch, alone or with fibrin sealant, demonstrated comparable efficacy in preventing CSF leak compared to multiple product combinations. The study does not demonstrate superiority, but shows a reassuring safety profile and similar rates of secondary outcomes, including pseudomeningocele, hospital readmissions, surgical site infections and adverse events, in both groups. These findings support the PEG-coated patch as a safe dural sealing option in elective non-traumatic posterior fossa surgery, while potential workflow or economic advantages remain to be formally evaluated in future studies.</div></div>","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101777"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146087900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The longest documented survival after cranial trepanation in the Renaissance: The thirteen years’ exceptional survival in Vespasiano Gonzaga Colonna","authors":"Annalisa Pace ,&nbsp;Cecilia Carubbi ,&nbsp;Luigi Cofone ,&nbsp;Marco Vitale ,&nbsp;Mauro Palmieri ,&nbsp;Ivano Pindinello ,&nbsp;Yaroslava Longhitano ,&nbsp;Marco Artico","doi":"10.1016/j.neuchi.2026.101790","DOIUrl":"10.1016/j.neuchi.2026.101790","url":null,"abstract":"<div><div>This essay focuses on the Vespasiano Gonzaga Colonna (1531–1591), a remarkable example of long-term life following cranial trepanation during the Renaissance. Gonzaga suffered from syphilis and frequent migraines; therefore, in 1578, his court surgeon used a scraping procedure to perform cranial trepanation. The right parietal bone had obvious indications of healing, and osteological data from his tomb validated the surgery. One of the longest reported survivors following cranial trepanation in the Italian archaeological record, Gonzaga, lived for 13 years after the treatment. This instance adds to the historical understanding of trepanation as one of the earliest neurosurgical procedures, and demonstrates the high degree of surgical expertise attained in early modern noble courts.</div></div>","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101790"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal pneumocephalus caused by Clostridium perfringens bacteremia originating from emphysematous cystitis after stroke-related blood–brain barrier disruption","authors":"Cyril Pernod ,&nbsp;Baptiste Quilly ,&nbsp;Philippe Lavrard ,&nbsp;Hilaire de Malleray ,&nbsp;Johan Schmitt ,&nbsp;Nathan Beucler","doi":"10.1016/j.neuchi.2026.101788","DOIUrl":"10.1016/j.neuchi.2026.101788","url":null,"abstract":"<div><div>Infectious pneumocephalus is rare and usually associated with meningitis or neurosurgical procedures. We report a fatal case of diffuse pneumocephalus caused by <em>Clostridium perfringens</em> bacteremia originating from emphysematous cystitis in a patient recently admitted for a large right middle cerebral artery infarction. Imaging demonstrated subarachnoid gas strictly confined to the infarcted hemisphere, followed by subdural air accumulation and fatal mass effect. We hypothesize that stroke-related blood–brain barrier disruption permitted hematogenous bacterial and gas diffusion into the subarachnoid space. This case highlights the distinction between negative-pressure postoperative pneumocephalus and positive-pressure infectious pneumocephalus in a closed skull.</div></div>","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101788"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147312365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Robotic hydrocephalus surgery: A systematic review of the effectiveness in neurosurgical interventions” [Neurochirurgie (2025) 101677]","authors":"Paweł Łajczak,&nbsp;Anna Łajczak,&nbsp;Stanisław Buczkowski,&nbsp;Kamil Jóźwik,&nbsp;Przemysław Nowakowski","doi":"10.1016/j.neuchi.2026.101789","DOIUrl":"10.1016/j.neuchi.2026.101789","url":null,"abstract":"","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101789"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147373265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educational quality and reliability of neurosurgical content on YouTube: a systematic review and meta-analysis","authors":"Fritz Fidel Váscones-Román ,&nbsp;Martin Alonso Hemeryth-Rengifo ,&nbsp;Jack Váscones-Román ,&nbsp;Martha Isabel Vilca-Salas ,&nbsp;Nuria Arlette Rodriguez-Aguilar ,&nbsp;Renzo Ugaz ,&nbsp;Diego Alonso Quiroz-Marcelo ,&nbsp;Nagheli Borjas ,&nbsp;Niels Pacheco-Barrios","doi":"10.1016/j.neuchi.2026.101795","DOIUrl":"10.1016/j.neuchi.2026.101795","url":null,"abstract":"<div><h3>Introduction</h3><div>YouTube is increasingly used for neurosurgical learning; however, the educational quality, transparency, and reliability of neurosurgery-related content—and whether these features differ by video source—remain unclear.</div></div><div><h3>Objective</h3><div>To synthesize published evaluations of neurosurgical YouTube videos and meta-analyze standardized quality/reliability scores, exploring source- and time-related differences and reporting gaps in validation and procedural completeness.</div></div><div><h3>Methods</h3><div>Following PRISMA, we searched PubMed, Scopus, Embase, and Web of Science (2017–2024) for studies assessing neurosurgical YouTube videos using standardized tools (DISCERN/mDISCERN, JAMA Benchmark, Global Quality Score [GQS]). Data were pooled using random-effects meta-analysis with Hartung–Knapp adjustment; scores were also transformed to the Proportion of Maximum Possible (POMP, 0–100).</div></div><div><h3>Results</h3><div>Sixteen studies (12–1,233 videos each) were included. On native scales, pooled means were: DISCERN per-item 3.06/5, DISCERN total 30.1/80, JAMA 2.41/4, and GQS 3.04/5. Harmonized POMP point estimates (0–100) were: DISCERN 39.8, JAMA 60.3, and GQS 51.0. Heterogeneity was substantial (I² &gt; 95%) except for DISCERN total (I² = 0%). Subgroup analyses suggested higher scores for institutional versus non-institutional sources, although meta-regression did not confirm significance. Validation and procedural completeness were infrequently reported.</div></div><div><h3>Conclusion</h3><div>Neurosurgical YouTube content shows moderate-to-low educational quality with substantial inconsistency. Institutional sources may perform better, but gaps in transparency, validation, structure, and procedural completeness are common. Standardized production criteria and curated peer-reviewed repositories may improve safe integration into neurosurgical education.</div></div><div><h3>Clinical trial number</h3><div>Not applicable</div></div>","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101795"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147373185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledging our reviewers","authors":"","doi":"10.1016/j.neuchi.2026.101776","DOIUrl":"10.1016/j.neuchi.2026.101776","url":null,"abstract":"","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101776"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender and leadership equity in neurosurgery: a systematic review of representation and authorship trends (2000–2025)","authors":"Tomasz Tykocki ,&nbsp;Mohamed Eltayeb","doi":"10.1016/j.neuchi.2026.101778","DOIUrl":"10.1016/j.neuchi.2026.101778","url":null,"abstract":"<div><h3>Background</h3><div>Neurosurgery remains one of the least gender-diverse surgical specialties. We quantified gender representation across the neurosurgical pipeline and assessed authorship and mentorship patterns.</div></div><div><h3>Methods</h3><div>: PRISMA-compliant systematic review (2000–2025) of databases and neurosurgical society sources. Random-effects models were used to pool proportions; meta-regression estimated temporal trends; mentorship effect was analyzed as odds ratio for female first authorship when the senior author was female.</div></div><div><h3>Results</h3><div>Thirty-eight studies (27 workforce/leadership; 11 authorship/editorial) from 75 countries (&gt;40,000 neurosurgeons) were included. Female residents: 20.2% (95% CI 18.0–22.5); female consultants: 18.9% (95% CI 16.1–21.8); female department chairs: 4.5% (95% CI 3.2–5.9). Female first authors: 16.9%; female senior authors: 8.9%; female–female pairs: 2.1%. Female senior authorship more than doubled the odds of a female first author (pooled OR 2.43; 95% CI 1.86–3.17).</div><div>Thirty-eight studies from 75 countries were included, representing &gt;40,000 neurosurgeons. Women accounted for 20.2% (95% CI 18.0–22.5) of trainees, 18.9% (95% CI 16.1–21.8) of practicing neurosurgeons, and 4.5% (95% CI 3.2–5.9) of department leaders. Female first authorship was 16.9% and senior authorship 8.9%. Female senior authors more than doubled the odds of female first authorship (OR 2.43; 95% CI 1.86–3.17).</div></div><div><h3>Conclusion</h3><div>Entry into neurosurgery has improved for women, but leadership and senior authorship remain disproportionately male. Increasing the number of women in senior roles is likely to have a multiplicative effect on authorship and visibility.</div></div>","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 2","pages":"Article 101778"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Globalizing Neurotrauma Prognostication: Integrating Cultural Context and Computational Intelligence in Pediatric TBI Research","authors":"Riza Amalia","doi":"10.1016/j.neuchi.2025.101750","DOIUrl":"10.1016/j.neuchi.2025.101750","url":null,"abstract":"","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 1","pages":"Article 101750"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145589417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Among Preoperative and Intraoperative Contralateral Analysis along the Perivascular Space Indexes and Postoperative Mini-Mental State Examination Scores in Newly Diagnosed Glioblastoma","authors":"Ryohei Ono,&nbsp;Shunichiro Miki,&nbsp;Alexander Zaboronok,&nbsp;Eiichi Ishikawa","doi":"10.1016/j.neuchi.2025.101752","DOIUrl":"10.1016/j.neuchi.2025.101752","url":null,"abstract":"<div><h3>Objective</h3><div>Analysis along the Perivascular Space (ALPS) index has been proposed as a quantitative magnetic resonance imaging (MRI) marker for evaluating the function of the brain’s glia-dependent waste clearance pathway, known as the glymphatic system. We hypothesized that the ALPS index on the contralateral side of the brain lesion may relate to postoperative memory disturbance. This study aimed to evaluate the relationship among the preoperative and intraoperative contralateral ALPS indexes and postoperative mini-mental state examination (MMSE) scores in patients with newly diagnosed glioblastoma (GBM).</div></div><div><h3>Methods</h3><div>Thirty-three patients with newly diagnosed, solitary GBMs who underwent intraoperative MRI and diffusion tensor imaging (DTI) were enrolled in this retrospective study. Patient data included tumor volume, peritumoral edema volume, preoperative and postoperative MMSE scores, and the preoperative and intraoperative contralateral ALPS index.</div></div><div><h3>Results</h3><div>A higher preoperative ALPS index was associated with older age, and a significant negative correlation was observed between the preoperative ALPS index and MMSE scores both before and after surgery, while the index was unrelated to the degree of improvement in the MMSE scores. Unexpectedly, the intraoperative ALPS index tended to show a negative correlation with the postoperative MMSE score and showed a strong correlation with the degree of improvement in the MMSE scores.</div></div><div><h3>Conclusions</h3><div>These findings suggest that the contralateral glymphatic pathway may associated with irreversible higher brain dysfunction in GBM patients. However, further studies are needed to confirm this speculation.</div></div>","PeriodicalId":51141,"journal":{"name":"Neurochirurgie","volume":"72 1","pages":"Article 101752"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145574887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}