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The Hematopoietic Potential of Tamarillo (Cyphomandra betacea) and Pitaya (Hylocereus spp.) Juices in Anemia Management: A Randomized Controlled Trial in Bukittinggi, West Sumatra, Indonesia 玉露（Cyphomandra betacea）和番荔枝（Hylocereus spp：在印度尼西亚西苏门答腊武吉廷吉进行的随机对照试验
Eureka Herba Indonesia Pub Date : 2024-07-24 DOI: 10.37275/ehi.v5i3.125
Desri Nova, Yeltra Armi, Mutia Felina, Zaharatul Hikmah, Riri Aprianti, Eureka Herba
{"title":"The Hematopoietic Potential of Tamarillo (Cyphomandra betacea) and Pitaya (Hylocereus spp.) Juices in Anemia Management: A Randomized Controlled Trial in Bukittinggi, West Sumatra, Indonesia","authors":"Desri Nova, Yeltra Armi, Mutia Felina, Zaharatul Hikmah, Riri Aprianti, Eureka Herba","doi":"10.37275/ehi.v5i3.125","DOIUrl":"https://doi.org/10.37275/ehi.v5i3.125","url":null,"abstract":"Anemia is a global health concern, particularly prevalent in developing countries. Traditional remedies like tamarillo and pitaya have been suggested to boost blood production. This study aimed to evaluate the efficacy and safety of these juices in managing anemia. A randomized, double-blind, placebo-controlled trial was conducted in Bukittinggi, West Sumatra, Indonesia. Participants with mild to moderate anemia (hemoglobin 8-11 g/dL) were randomized to receive daily tamarillo juice, pitaya juice, or a placebo for 12 weeks. Hemoglobin, hematocrit, iron levels, and hematological parameters were assessed at baseline and week 12. A total of 150 participants completed the study (50 per group). Both tamarillo and pitaya juice groups showed significant increases in hemoglobin and hematocrit levels compared to the placebo group (p < 0.05). Pitaya juice also demonstrated a significant increase in iron levels (p < 0.01). No serious adverse events were reported. Tamarillo and pitaya juices show promise as adjunctive therapies for anemia management. Further research is needed to explore their long-term effects and mechanisms of action.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"47 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Topical Virgin Coconut Oil on Striae Gravidarum Prevention and Severity: A Randomized Controlled Trial 外用初榨椰子油对预防妊娠纹和妊娠纹严重程度的影响：随机对照试验
Eureka Herba Indonesia Pub Date : 2024-07-22 DOI: 10.37275/ehi.v5i3.124
Rahmatul Ulya, Sunesni, Yohana Suganda, Mekar Zenni Radhia, Eureka Herba
{"title":"The Effect of Topical Virgin Coconut Oil on Striae Gravidarum Prevention and Severity: A Randomized Controlled Trial","authors":"Rahmatul Ulya, Sunesni, Yohana Suganda, Mekar Zenni Radhia, Eureka Herba","doi":"10.37275/ehi.v5i3.124","DOIUrl":"https://doi.org/10.37275/ehi.v5i3.124","url":null,"abstract":"Striae gravidarum (SG), commonly known as stretch marks, is a common concern during pregnancy. Virgin coconut oil (VCO) is traditionally used for skin health and may have potential in SG prevention. This randomized controlled trial (RCT) aimed to assess the efficacy of topical VCO in preventing and reducing the severity of SG among pregnant women in Kerinci Regency, Indonesia. Pregnant women (n=200) in their second trimester were randomized to receive either topical VCO or a placebo (standard emollient) twice daily. SG severity was assessed using a modified striae gravidarum assessment scale (SGAS) at baseline, 32 weeks gestation, and six weeks postpartum. VCO application was associated with a significantly lower incidence of new SG compared to the placebo (25% vs. 45%, p < 0.05). Furthermore, the VCO group showed a significant reduction in SG severity at 32 weeks and postpartum (mean SGAS scores: VCO 1.8 vs. placebo 2.6 at 32 weeks, p < 0.05; VCO 1.4 vs. placebo 2.2 at postpartum, p < 0.01). No adverse effects were reported. In conclusion, topical VCO appears to be safe and effective in preventing new SG and reducing the severity of existing SG during pregnancy. Further research is warranted to explore the underlying mechanisms and long-term effects.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"71 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141817742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential of Ethanol Extract of Red Gedi Leaves (Abelmoschus manihot L. Medik) Against Endogenous Antioxidant Activity in Rat Model of Diabetes Mellitus 红葛地叶（Abelmoschus manihot L. Medik）乙醇提取物在糖尿病大鼠模型中的内源性抗氧化活性潜力
Eureka Herba Indonesia Pub Date : 2024-07-04 DOI: 10.37275/ehi.v5i3.123
Annora Rizky, Alfina Nurrahman, Dewi Weni Sari, Muhammad Firdaus
{"title":"Potential of Ethanol Extract of Red Gedi Leaves (Abelmoschus manihot L. Medik) Against Endogenous Antioxidant Activity in Rat Model of Diabetes Mellitus","authors":"Annora Rizky, Alfina Nurrahman, Dewi Weni Sari, Muhammad Firdaus","doi":"10.37275/ehi.v5i3.123","DOIUrl":"https://doi.org/10.37275/ehi.v5i3.123","url":null,"abstract":"Diabetes mellitus (DM) is characterized by chronic hyperglycemia and increased oxidative stress, contributing to disease complications. Red gedi leaves (Abelmoschus manihot L. Medik) are rich in bioactive compounds, including tannins, saponins, alkaloids and flavonoids, with antioxidant potential. This study aims to evaluate the effect of ethanol extract of red gedi leaves on endogenous antioxidant activity in rat model of DM induced by STZ-NA. Male rats were induced with DM with streptozotocin (STZ)-NA. Rats were divided into five groups: normal control (KN), DM control (KDM), glibenclamide positive control (KPG), and group treated with red gedi leaf extract at a dose of 100 mg/kgBW (GEDI 100), 200 mg/kgBW (GEDI 200), and 400 mg/kgBW (GEDI 400). The parameters observed included blood glucose levels, malondialdehyde (MDA) as a marker of oxidative stress, as well as the activity of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in liver tissue. Data analysis used one-way ANOVA and Tukey's post hoc test (p<0.05). The results showed that the yield of ethanol extract from red gedi leaves was 6.984%. Administration of red gedi leaf extract at a dose of 400 mg/kgBW (GEDI 400) significantly reduced blood glucose levels (p<0.05) and MDA (p<0.05), and increased the activity of SOD (p<0.05), CAT (p<0.05), and GPx (p<0.05) in DM rats compared to the DM control group (KDM). The effect of GEDI 400 was comparable to the effect of glibenclamide as a positive control. The ethanol extract of red gedi leaves at a dose of 400 mg/kgBW was effective in increasing endogenous antioxidant activity and reducing oxidative stress in STZ-NA-induced DM rats, showing potential as an antioxidant and antidiabetic agent.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":" 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Ethnopharmacological Studies on the Use of the Sambiloto Plant in the Treatment of Malaria in the Asmat Tribal Community in Papua, Indonesia 印度尼西亚巴布亚阿斯马特部落社区利用桑比洛托植物治疗疟疾的民族药理学研究分析
Eureka Herba Indonesia Pub Date : 2024-03-07 DOI: 10.37275/ehi.v5i2.118
Esther Lea Awotauw, Ruth Maria Panggabean
{"title":"Analysis of Ethnopharmacological Studies on the Use of the Sambiloto Plant in the Treatment of Malaria in the Asmat Tribal Community in Papua, Indonesia","authors":"Esther Lea Awotauw, Ruth Maria Panggabean","doi":"10.37275/ehi.v5i2.118","DOIUrl":"https://doi.org/10.37275/ehi.v5i2.118","url":null,"abstract":"Introduction: Malaria is still a major health problem in Indonesia, especially in the Papua region. The Asmat tribe has traditional knowledge about the use of medicinal plants to treat malaria, one of which is sambiloto. \u0000Methods: This research uses a qualitative observational research design with an ethnopharmacological approach. This approach combines aspects of ethnography and pharmacology to study traditional knowledge and the use of medicinal plants in a community. \u0000Results: It was discovered that sambiloto has long been used by the Asmat tribe to treat malaria. Sambiloto leaf is processed into a decoction or juice and drunk to relieve malaria symptoms such as fever, chills, and headaches. \u0000Conclusion: This ethnopharmacological study shows that sambiloto has potential as an herbal medicine for treating malaria in the Asmat community. Further research is needed to test the effectiveness and safety of sambiloto in the treatment of malaria.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"25 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140259776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential of Legetan Leaves (Acmella oleracea) as a Therapeutic Modality for Osteoarthritis: An In Vivo Study 乐果叶（Acmella oleracea）作为骨关节炎治疗方法的潜力：体内研究
Eureka Herba Indonesia Pub Date : 2024-03-06 DOI: 10.37275/ehi.v5i2.117
I. Indrayani
{"title":"Potential of Legetan Leaves (Acmella oleracea) as a Therapeutic Modality for Osteoarthritis: An In Vivo Study","authors":"I. Indrayani","doi":"10.37275/ehi.v5i2.117","DOIUrl":"https://doi.org/10.37275/ehi.v5i2.117","url":null,"abstract":"Introduction: Osteoarthritis (OA) is a degenerative joint disease characterized by inflammation and cartilage damage. Legetan leaves (Acmella oleracea) have anti-inflammatory and antioxidant potential that may help relieve OA symptoms. This study aims to evaluate the potential of legetan leaves as a therapeutic modality for OA in a rat model. \u0000Methods: Legetan leaf extract was formulated into an oral preparation and given to rats induced by OA with monosodium iodate. The positive control group received standard OA medications. Parameters measured include pain scores, joint inflammation, and cartilage damage. \u0000Results: Legetan leaf extract significantly reduced pain scores and joint inflammation in rats with OA. Legetan leaf extract also shows a protective effect against cartilage damage. \u0000Conclusion: Legetan leaves have potential as a therapeutic modality for OA.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"93 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140261521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Effectiveness of Kencur Warm Water Soaking with Salt Warm Water Against Leg Edema of Third Trimester Pregnant Women in the Working Area of Rawang Health Center, Indonesia 印度尼西亚拉旺保健中心工作区的 Kencur 温水浸泡与盐温水浸泡对第三孕期孕妇腿部水肿的效果比较
Eureka Herba Indonesia Pub Date : 2024-02-12 DOI: 10.37275/ehi.v5i1.114
Riri Aprianti, Sintia Hikma Oktavia
{"title":"Comparison of the Effectiveness of Kencur Warm Water Soaking with Salt Warm Water Against Leg Edema of Third Trimester Pregnant Women in the Working Area of Rawang Health Center, Indonesia","authors":"Riri Aprianti, Sintia Hikma Oktavia","doi":"10.37275/ehi.v5i1.114","DOIUrl":"https://doi.org/10.37275/ehi.v5i1.114","url":null,"abstract":"Leg edema is a common complaint in third trimester pregnant women. It is believed that soaking in kencur warm water and salt warm water can help overcome this. Comparing the effectiveness of soaking in warm kencur water with warm salt water on leg edema in third trimester pregnant women. Quasi-experimental research with a pretest-posttest design with the control group. A total of 60 third trimester pregnant women were divided into two groups: the kencur warm water immersion group (n=30) and the salt warm water immersion group (n=30). The intervention was carried out for 15 minutes, twice a day for 3 days. Leg edema was measured using a measuring tape before and after the intervention. There was a significant reduction in leg edema in both groups after intervention (p<0.05). The reduction in leg edema in the kencur warm water immersion group was greater than in the salt warm water immersion group (p<0.05). Kencur warm water soaks are more effective than salt warm water soaks in reducing leg edema in third-trimester pregnant women.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"168 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139842805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Effectiveness of Kencur Warm Water Soaking with Salt Warm Water Against Leg Edema of Third Trimester Pregnant Women in the Working Area of Rawang Health Center, Indonesia 印度尼西亚拉旺保健中心工作区的 Kencur 温水浸泡与盐温水浸泡对第三孕期孕妇腿部水肿的效果比较
Eureka Herba Indonesia Pub Date : 2024-02-12 DOI: 10.37275/ehi.v5i1.114
Riri Aprianti, Sintia Hikma Oktavia
{"title":"Comparison of the Effectiveness of Kencur Warm Water Soaking with Salt Warm Water Against Leg Edema of Third Trimester Pregnant Women in the Working Area of Rawang Health Center, Indonesia","authors":"Riri Aprianti, Sintia Hikma Oktavia","doi":"10.37275/ehi.v5i1.114","DOIUrl":"https://doi.org/10.37275/ehi.v5i1.114","url":null,"abstract":"Leg edema is a common complaint in third trimester pregnant women. It is believed that soaking in kencur warm water and salt warm water can help overcome this. Comparing the effectiveness of soaking in warm kencur water with warm salt water on leg edema in third trimester pregnant women. Quasi-experimental research with a pretest-posttest design with the control group. A total of 60 third trimester pregnant women were divided into two groups: the kencur warm water immersion group (n=30) and the salt warm water immersion group (n=30). The intervention was carried out for 15 minutes, twice a day for 3 days. Leg edema was measured using a measuring tape before and after the intervention. There was a significant reduction in leg edema in both groups after intervention (p<0.05). The reduction in leg edema in the kencur warm water immersion group was greater than in the salt warm water immersion group (p<0.05). Kencur warm water soaks are more effective than salt warm water soaks in reducing leg edema in third-trimester pregnant women.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"17 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Content of Medicinal Chemicals in Traditional Herbal Medicine: A Systematic Literature Review 传统草药中的药用化学品含量：系统性文献综述
Eureka Herba Indonesia Pub Date : 2023-12-28 DOI: 10.37275/ehi.v5i1.105
Lia Fikayuniar, Mentari, Ainun Mar’atus Putri Warsito, Refriyanti Irma, Elista Indah Susanti, Eureka Herba
{"title":"Content of Medicinal Chemicals in Traditional Herbal Medicine: A Systematic Literature Review","authors":"Lia Fikayuniar, Mentari, Ainun Mar’atus Putri Warsito, Refriyanti Irma, Elista Indah Susanti, Eureka Herba","doi":"10.37275/ehi.v5i1.105","DOIUrl":"https://doi.org/10.37275/ehi.v5i1.105","url":null,"abstract":"Jamu is a traditional medicine made from natural ingredients that are known to be inherited from generation to generation for health. The more widespread the use of traditional medicines is, the more opportunities there are for the adulteration of the ingredients. There are even some herbal medicines that contain medicinal chemicals (BKO). Traditional medicines are prohibited from containing BKO because the BKO content in herbal medicine can be a source of danger in herbal medicine. The method used in this research is data collection carried out by searching databases taken from various scientific articles sourced from PubMed, Science Direct, ResearchGate, WoS (Web of Science), and Google Scholar with articles that have been published from 2013 - 2023. The results that have been obtained from several studies that have been carried out show that there is BKO content in traditional herbal medicine that has been circulating in the community, such as paracetamol, mefenamic acid, phenylbutazone, allopurinol, piroxicam, prednisone, and others.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"5 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139148757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical Analysis and Potential Pharmacological Activity of Frangipani Flower Simplicia (Plumeria spp.) as a Source of Medicinal Ingredients 作为药用成分来源的佛手兰花辛夷（Plumeria spp.）的植物化学分析和潜在药理活性
Eureka Herba Indonesia Pub Date : 2023-12-18 DOI: 10.37275/ehi.v5i1.104
Evi Riszka Nurhapit, Fitri Nurfadhilla, Ilham Bintang Pratama, Marsella Mideliani Jured, Sigit Roma Rezki, Harahap, Wipena Fariza, Article Info, Eureka Herba
{"title":"Phytochemical Analysis and Potential Pharmacological Activity of Frangipani Flower Simplicia (Plumeria spp.) as a Source of Medicinal Ingredients","authors":"Evi Riszka Nurhapit, Fitri Nurfadhilla, Ilham Bintang Pratama, Marsella Mideliani Jured, Sigit Roma Rezki, Harahap, Wipena Fariza, Article Info, Eureka Herba","doi":"10.37275/ehi.v5i1.104","DOIUrl":"https://doi.org/10.37275/ehi.v5i1.104","url":null,"abstract":"Frangipani flower simplicia contains various phytochemical compounds, such as alkaloids, flavonoids, saponins, and tannins. These phytochemical compounds have the potential to have various pharmacological activities, such as antibacterial, antifungal, anti-inflammatory, antioxidant, and anticancer. This study aims to explore the phytochemical analysis and potential pharmacological activity of frangipani flower simplicia (Plumeria spp.) as a source of medicinal ingredients. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding phytochemical analysis and potential pharmacological activity of frangipani flower simplicia (Plumeria spp.). The frangipani flower is a traditional medicinal plant that has various benefits. The phytochemical content contained in frangipani flowers, such as alkaloids, flavonoids, saponins, and tannins, has the potential to have various pharmacological activities, such as antibacterial, antifungal, anti-inflammatory, antioxidant, and anticancer.","PeriodicalId":510746,"journal":{"name":"Eureka Herba Indonesia","volume":"8 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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