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Drug information centers: an overview. 药物信息中心:概述。
Drug Information Journal Pub Date : 1986-01-01 DOI: 10.1177/009286158602000209
A B Amerson
{"title":"Drug information centers: an overview.","authors":"A B Amerson","doi":"10.1177/009286158602000209","DOIUrl":"https://doi.org/10.1177/009286158602000209","url":null,"abstract":"<p><p>Drug information centers have existed for more than 20 years. Well over 100 centers function across the country, primarily affiliated with hospitals and/or colleges of pharmacy. The centers serve an audience of primarily health professionals but in some settings meet consumer needs. Three general areas of responsibility exist: service, education and research. In the area of service, specific functions such as answering questions, supporting the Pharmacy and Therapeutics Committee, and preparing newsletters are frequent. Educational responsibilities often include teaching pharmacy students drug information skills. Evaluation of the services has focused mostly on answering questions and Pharmacy and Therapeutics (P&T) Committee functions. Commercial information systems used by Drug Information Centers (DICs) are increasingly sophisticated and offer the opportunity to improve efficiency. Funding generally is provided by the institution with which the center is affiliated. Attempts to charge for services have provided only modest revenue. Drug information centers continue to mature and offer a useful service.</p>","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"20 2","pages":"173-8"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158602000209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21145808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A drug information-ADR collection network: the French system. 药品信息-不良反应收集网络:法国系统。
Drug Information Journal Pub Date : 1986-01-01 DOI: 10.1177/009286158602000315
J Dangoumau, G Lagier, R J Royer
{"title":"A drug information-ADR collection network: the French system.","authors":"J Dangoumau,&nbsp;G Lagier,&nbsp;R J Royer","doi":"10.1177/009286158602000315","DOIUrl":"https://doi.org/10.1177/009286158602000315","url":null,"abstract":"This article presents the French Drug Information and Adverse Drug Reaction Collection network.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"20 3","pages":"337-46"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158602000315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21188550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
A clinical pharmacologic perspective on the detection and assessment of adverse drug reactions. 从临床药理学角度探讨药物不良反应的检测与评估。
Drug Information Journal Pub Date : 1986-01-01 DOI: 10.1177/009286158602000403
C A Naranjo
{"title":"A clinical pharmacologic perspective on the detection and assessment of adverse drug reactions.","authors":"C A Naranjo","doi":"10.1177/009286158602000403","DOIUrl":"https://doi.org/10.1177/009286158602000403","url":null,"abstract":"<p><p>The study of a new drug includes the assessment of its pharmacologic effects, benefits (efficacy), and risks (safety). Most recent drug discontinuations in the United States and the United Kingdom have been associated with problems of safety. The assessment of clinical drug safety is difficult. Those assessing drug safety are confronted with the need to make causality assessment judgments of drug-related events. Several procedures for assessing causality of adverse reactions have been proposed; however, none of them is completely satisfactory. Global introspection (the unaided judgment based on knowledge and experience) and the currently available standardized decision aids (questionnaires or algorithms) have serious limitations that hamper their use. There is a need for better procedures.</p>","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"20 4","pages":"387-93"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158602000403","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32079657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Reliability of adverse drug reaction assessment in psychiatric inpatients. 精神科住院患者药物不良反应评估的可靠性。
Drug Information Journal Pub Date : 1986-01-01 DOI: 10.1177/009286158602000318
R Grohmann, P Dirschedl, J Scherer, L G Schmidt, O Wunderlich
{"title":"Reliability of adverse drug reaction assessment in psychiatric inpatients.","authors":"R Grohmann,&nbsp;P Dirschedl,&nbsp;J Scherer,&nbsp;L G Schmidt,&nbsp;O Wunderlich","doi":"10.1177/009286158602000318","DOIUrl":"https://doi.org/10.1177/009286158602000318","url":null,"abstract":"Within an ongoing drug surveillance program in psychiatric hospitals, the applicability of an algorithm for judgment on probability of causal relationship of adverse events and drug therapy was tested. Algorithmic inter-rater agreement was compared to agreement obtained with the conventional criteria used so far within the program in 80 cases by two raters, who had participated in the drug surveillance program since its beginning in 1979. Agreement on total judgment was comparable to results from similar studies in the literature using various algorithms, but in contrast to all these studies a higher percent of agreement (80%) was obtained with the use of the conventional criteria in this study than with the use of the algorithm (69%). Possible explanations and consequences are discussed.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"20 3","pages":"357-61"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158602000318","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21147313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Compass Data Base 罗盘数据库
Drug Information Journal Pub Date : 1985-07-01 DOI: 10.1177/009286158501900311
M. Lee Morse
{"title":"The Compass Data Base","authors":"M. Lee Morse","doi":"10.1177/009286158501900311","DOIUrl":"https://doi.org/10.1177/009286158501900311","url":null,"abstract":"COMPASS is a patient speci’jiic data base containing the longitudinal medical/pharmaceutical event histories of 5.25 million Medicaid recipients in the Llniled States. Sophisticated epidemiologic software is used to process and retrieve phormaceutical exposure and medical event data for conducting post-marketing drug surveillance studies. To date, several studies have been conducted using COMPASS which corraborate findings in more traditional settings. Although important limitations of the COMPASS data are known, the data bases advantages suggest a useful role in PMS studies.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"19 1","pages":"249 - 252"},"PeriodicalIF":0.0,"publicationDate":"1985-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158501900311","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64843014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Format, organization, and processing of registration dossiers in the European Economic Community (EEC). 欧洲经济共同体(EEC)注册档案的格式、组织和处理。
Drug Information Journal Pub Date : 1985-01-01 DOI: 10.1177/009286158501900101
D Poggiolini
{"title":"Format, organization, and processing of registration dossiers in the European Economic Community (EEC).","authors":"D Poggiolini","doi":"10.1177/009286158501900101","DOIUrl":"https://doi.org/10.1177/009286158501900101","url":null,"abstract":"<p><p>The free circulation of drugs among the European Economic Community (EEC) member states ensues from the principles stated by the Treaty of Rome. This is possible thanks to a series of legal and technical directives stating the criteria with which the national authorities--who are sovereign in this matter--must comply. These directives are briefly explained. In particular, the procedure by which the initial authorization, granted by one member state, can be extended to at least five others is presented. The content and order of the registration dossier is presented in detail.</p>","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"19 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158501900101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21188515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Public drug information: a telephone-based model for patient education. 公共药品信息:基于电话的患者教育模式。
Drug Information Journal Pub Date : 1985-01-01 DOI: 10.1177/009286158501900102
S G Bryant, B G Guernsey, W H Doutre, B Mansbridge, S Fisher
{"title":"Public drug information: a telephone-based model for patient education.","authors":"S G Bryant,&nbsp;B G Guernsey,&nbsp;W H Doutre,&nbsp;B Mansbridge,&nbsp;S Fisher","doi":"10.1177/009286158501900102","DOIUrl":"https://doi.org/10.1177/009286158501900102","url":null,"abstract":"<p><p>As one facet of a larger investigation evaluating the various means by which patients receive information concerning their medications, a telephone-based drug information service was established for selected public use. The purpose was to detail the growth and utilization of the service, characterize the type and importance of the questions asked, and compare the potential utility with that of the USP-DI patient package insert (PPI) in responding to the public's drug information requests. Availability of the toll-free number for the Prescription Drug Information Service (PDIS) was controlled by offering it only to outpatients receiving selected medicines from the pharmacy of a large university-based medical center. The PDIS was operated by clinical pharmacists who participated in completing standardized operational data forms after each drug information call by the public. Of those calls received, 91.7% were not of a serious nature and most commonly dealt with side effects, drug interactions, and drug identification. Fifty percent of first-time calls occurred within two days of the subject's visit to the pharmacy and 23.4% of the total PDIS calls were repeat contacts. Interestingly, 34% of the patients' questions could not have been answered using the standard USP-DI PPI.</p>","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"19 1","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158501900102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21139573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
An international survey of drug information centers. 国际毒品信息中心调查。
Drug Information Journal Pub Date : 1985-01-01 DOI: 10.1177/009286158501900109
G R Gallo, A I Wertheimer
{"title":"An international survey of drug information centers.","authors":"G R Gallo,&nbsp;A I Wertheimer","doi":"10.1177/009286158501900109","DOIUrl":"https://doi.org/10.1177/009286158501900109","url":null,"abstract":"<p><p>A questionnaire was developed to characterize the location, operation, personnel, reference resources, and functions of drug information centers in countries throughout the world other than the United States. The questionnaire was mailed to 100 drug information centers or pharmacy practitioners (primarily faculty) in 65 countries. The majority of drug information centers responding to this questionnaire were located at and funded by university based hospitals. Most were open eight hours per day and engaged in the following activities: answering requests for information, publishing pharmacy bulletins, teaching, continuing education, and providing information directly to pharmacy and therapeutics committees. Additional information gathered from this survey included: common references and journals maintained by drug information centers, user demographics, and a request profile. Although many similarities among the information centers were found, interesting observations regarding their differences may be made. It is important that drug information centers share their experiences so that others may learn about their new and innovative programs.</p>","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"19 1","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158501900109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21139572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Effect of ten specific questions on nationwide drug information center activity. 十个具体问题对全国药品信息中心活动的影响。
Drug Information Journal Pub Date : 1985-01-01 DOI: 10.1177/009286158501900112
J M Fisher
{"title":"Effect of ten specific questions on nationwide drug information center activity.","authors":"J M Fisher","doi":"10.1177/009286158501900112","DOIUrl":"https://doi.org/10.1177/009286158501900112","url":null,"abstract":"A survey of drug information centers (DICs) was performed to determine (1) the number of requests received and (2) the amount of manpower used in answering requests for frequently sought information dealing with ten specific topics. A total of 2,968 requests for information on ten topics was received by the 41 DICs, representing 3% of all questions received. The number of requests for information on each topic ranged from 27 to 724, and over half of the DICs received at least one request for information on nine of the ten topics. A total of 1,206 man-hours was used by the DICs to answer requests for information on all topics combined. It is concluded that DICs overlap substantially in the provision of frequentlly sought information.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"19 1","pages":"75-9"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158501900112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21139574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A consumer perspective. 消费者的视角。
Drug Information Journal Pub Date : 1985-01-01 DOI: 10.1177/009286158501900216
M M Heslin
{"title":"A consumer perspective.","authors":"M M Heslin","doi":"10.1177/009286158501900216","DOIUrl":"https://doi.org/10.1177/009286158501900216","url":null,"abstract":"<p><p>The consumer's perspective of over-the-counter medication should be one of the most important determinants of strategy for individuals and companies manufacturing and distributing such products. The consumers, buyers, and users have been telling industry for a long time that they are concerned with safety, cost, effectiveness, and availability of choice. The wise producers have begun to heed the signs and the public is responding.</p>","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"19 2","pages":"159-61"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158501900216","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21144891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
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