M. Mésidor, Caroline Sirois, J. Guertin, M. E. Schnitzer, Bernard Candas, C. Blais, Benoit Cossette, Paul Poirier, James M. Brophy, Lisa Lix, Mina Tadrous, Awa Diop, Denis Hamel, Denis Talbot
{"title":"Effect of statin use for the primary prevention of cardiovascular disease among older adults: A cautionary tale concerning target trials emulation","authors":"M. Mésidor, Caroline Sirois, J. Guertin, M. E. Schnitzer, Bernard Candas, C. Blais, Benoit Cossette, Paul Poirier, James M. Brophy, Lisa Lix, Mina Tadrous, Awa Diop, Denis Hamel, Denis Talbot","doi":"10.1016/j.jclinepi.2024.111284","DOIUrl":"https://doi.org/10.1016/j.jclinepi.2024.111284","url":null,"abstract":"","PeriodicalId":510190,"journal":{"name":"Journal of Clinical Epidemiology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139812192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Voluntary transparency of sponsors of medicines clinical trials is exceptional","authors":"R. Dal-Ré","doi":"10.1016/j.jclinepi.2024.111282","DOIUrl":"https://doi.org/10.1016/j.jclinepi.2024.111282","url":null,"abstract":"","PeriodicalId":510190,"journal":{"name":"Journal of Clinical Epidemiology","volume":"1 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139826902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using the GRADE Evidence to Decision Framework to reach recommendations together with ethnic minority community organisations: the example of COVID-19 vaccine uptake in the UK.","authors":"Shaun Treweek, Miriam Brazzelli, Annette Crosse, Sunil Daga, Talia Isaacs, Ria Sunga","doi":"10.2139/ssrn.4489633","DOIUrl":"https://doi.org/10.2139/ssrn.4489633","url":null,"abstract":"OBJECTIVE\u0000To make recommendations regarding factors that affect COVID-19 vaccine uptake by ethnic minority individuals in the UK, together with strategies that could be used to increase uptake.\u0000\u0000\u0000STUDY DESIGN AND SETTING\u0000The results of two rapid systematic reviews- one identifying factors that affect respiratory vaccine uptake in ethnic minority adults, the other identifying experimental evaluations of strategies to increase vaccine uptake in ethnic minority adults- were put into GRADE Evidence to Decision Frameworks to support discussion with a panel of ethnic minority community organisations, community-focused small companies and academics of the relevance of the review findings to the UK COVID context. Aided by the Frameworks, the panel made recommendations for factors that need to be addressed to increase vaccine uptake, and for which strategies might be used to increase uptake.\u0000\u0000\u0000RESULTS\u0000Our two reviews contained 31 relevant research studies published in English between 2016 and 2021, all of which were from the UK (8/31), the US (20) and Australia (3). We identified six factors- two linked to trust, three linked to information and one on accessibility - that affected uptake. Strategies that had been evaluated fell into three categories: using trusted messengers, tailoring the message and increasing convenience. These were put into GRADE Evidence to Decision Frameworks and discussed over a series of meetings with individuals from nine ethnic minority community organisations, two community-focused small companies and academics. Community partners provided insight into why ethnic minority individuals in the UK had lower vaccine uptake, particularly with regard to the impact of non-health related UK Government policy on individuals' heath decision-making. Recommendations included recognising that trust will be low among some ethnic groups, thinking more broadly as to who messengers should be in a low-trust environment, ensuring that information is tailored to the information needs of specific ethnic groups and working to increase convenience. Our results are at https://www.collaborationforchange.co.uk.\u0000\u0000\u0000CONCLUSION\u0000GRADE Evidence to Decision Frameworks could be used more widely to structure discussions of research evidence between researchers, community organisations and other non-research partners.","PeriodicalId":510190,"journal":{"name":"Journal of Clinical Epidemiology","volume":"531 ","pages":"111268"},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140471213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}