The Egyptian Journal of Internal Medicine最新文献

{"title":"Silent spread of poliovirus type 2 variant (cVDPV) in Gaza","authors":"Mohd Sayeed Shaikh, Md. Faiyazuddin, Syed Sarfaraz Ali, Israrul H Ansari, Sanjit Sah, Rachana Mehta","doi":"10.1186/s43162-025-00466-1","DOIUrl":"https://doi.org/10.1186/s43162-025-00466-1","url":null,"abstract":"Abstract The silent spread of circulating vaccine-derived poliovirus type 2 (cVDPV2) in Gaza has become a major public health emergency, exacerbated by ongoing conflict, inadequate sanitation, and limited healthcare access. The virus was discovered in sewage samples from Khan Younis and Deir al Balah, and genetic analysis linked it to a strain found in Egypt in late 2023. The first polio case in Gaza in 25 years was confirmed in August 2024 in a 10-month-old child. This review explores the epidemiology of cVDPV2 in Gaza, its relationship to regional strains, and the risk factors that exacerbate transmission. It describes the role of various polio vaccines, including the novel oral polio vaccine type 2 (nOPV2), in emergency campaigns coordinated by WHO, UNICEF, and the Palestinian Ministry of Health. The review further explores into Gaza’s unique “Gaza system” of combined vaccination, the challenges of maintaining cold-chain logistics, and the significance of wastewater surveillance. To contain the outbreak and prevent poliomyelitis from resurging in vulnerable populations, humanitarian access, ceasefire enforcement, and global cooperation are urgently needed.","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ejim.springeropen.com/counter/pdf/10.1186/s43162-025-00466-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147921019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of complications and outcome in live kidney transplant recipients at 1 year—a single center experience","authors":"Imran Khan, Muzamil Ahmad Wani, Imtiyaz Ahmad Wani, Jawad Iqbal Rather, Mohammad Ashraf Bhat, Muzafar Maqsood Wani, Rayees Yousuf Sheikh, Manzoor Parry","doi":"10.1186/s43162-025-00414-z","DOIUrl":"https://doi.org/10.1186/s43162-025-00414-z","url":null,"abstract":"Abstract Introduction Patients with end-stage kidney disease (ESKD) need ongoing dialysis treatments or a kidney transplant to survive. Kidney transplantation is the optimal treatment for patients with ESKD. Advances in surgical, immunosuppressive, and monitoring protocols have led to a significant improvement in short-term kidney allograft survival. However, in order to avoid rejection, kidney transplant patients have to be on immunosuppression which increases the risk of infections, malignancies, cardiovascular diseases, and many other complications. So a balance has to be struck to prevent under or over-immunosuppression. In this study, we present our experience and follow-up data of kidney transplantations done at our center with special emphasis on the incidence of complications and outcomes in recipients at 1 year. Aims and objectives 1. To estimate the incidence of post-transplant complications in live kidney transplant recipients at 1 year. 2. To assess the patient and graft survival at 1 year in live kidney transplant recipients. Materials and methods This observational study was done in the Department of Nephrology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, J&K. Patients who underwent transplant at our center from April 2022 to April 2023 were included and each patient was followed up for 1 year in this study. All the consenting kidney transplant recipients undergoing kidney transplantation at our center during the study period were included. Results A total of 45 kidney transplants were included in the study. The mean age of our study population was 31.2 years (SD 10.5). 77.5% of our recipient population comprised of men and 22.5% were women. The mean dialysis vintage was 15.1 months (SD 9.4). The incidence of biopsy-proven acute rejection was 15% while 1 year patient and graft survival were 100% and 95%, respectively. The incidence of BK virus-associated nephropathy was 10%. The overall incidence of other infections was 37.5%. The incidence of hypertension and post-transplant diabetes was 65% and 15%, respectively. The incidence of anemia and erythrocytosis was 12.5% and 22.5%, respectively. Conclusion Kidney transplant is the treatment of choice for ESKD. However, these patients are at risk of infectious, malignant, cardiometabolic, and other complications. Heightened awareness and surveillance is of utmost importance in these patients.","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s43162-025-00414-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147914199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic insights into renal diseases: advancements and implications","authors":"N. Aderinto, G. Olatunji, Emmanuel Kokori, I. Ogieuhi, Adetola Emmanuel Babalola, Komolafe Babajide Ayodeji, Muhammadul-Awwal Irodatullah Bisola, Ajekiigbe Victor Oluwatomiwa, Ibukunoluwa V. Ishola","doi":"10.1186/s43162-024-00341-5","DOIUrl":"https://doi.org/10.1186/s43162-024-00341-5","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"26 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gut microbiota-derived metabolites: implications for metabolic syndrome and therapeutic interventions","authors":"S. O. Olalekan, O. Bakare, I. Osonuga, Abayomi S Faponle, B. Adegbesan, Esther Nkechi Ezima","doi":"10.1186/s43162-024-00342-4","DOIUrl":"https://doi.org/10.1186/s43162-024-00342-4","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"33 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive role of platelets to lymphocytes ratio and neutrophil to lymphocytes ratio in COPD exacerbation","authors":"Hussien Fayiad, Ahmed Mohamed Amer","doi":"10.1186/s43162-024-00336-2","DOIUrl":"https://doi.org/10.1186/s43162-024-00336-2","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"74 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 and hospital activity: experience of the Nephrology Department of Ibn Sina Hospital-Rabat","authors":"Sara El Maakoul, Loubna Benamar, Naima Ouzeddoun, Tarik Bouattar","doi":"10.1186/s43162-024-00321-9","DOIUrl":"https://doi.org/10.1186/s43162-024-00321-9","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"9 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of different diet plans on patients with type 2 diabetes","authors":"Shaimaa Fathy, Amr El Meligi, Sahar S. AlWakil, Mohamed B. Ahmed, Ghada R. Ahmed","doi":"10.1186/s43162-024-00318-4","DOIUrl":"https://doi.org/10.1186/s43162-024-00318-4","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"2 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141108351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of serum uric acid level with metabolic risk factors in patients with type 2 diabetes and their relation to eGFR status","authors":"S. A. Argoons, Esraa Tarek Mahmoud, Rasha A. Madkour","doi":"10.1186/s43162-024-00319-3","DOIUrl":"https://doi.org/10.1186/s43162-024-00319-3","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"31 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141117988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monocyte lymphocyte ratio, IL 6, and their association with increased carotid intima-media thickness as simple predictive markers for nephropathy in Egyptian diabetic patients","authors":"Heba Mahmoud Mohamed Ibrahim, Heba Morad Bahgat, Deena Ahmed Sharshar, Tarek Abdel Azim Ramzy","doi":"10.1186/s43162-024-00284-x","DOIUrl":"https://doi.org/10.1186/s43162-024-00284-x","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139840899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monocyte lymphocyte ratio, IL 6, and their association with increased carotid intima-media thickness as simple predictive markers for nephropathy in Egyptian diabetic patients","authors":"Heba Mahmoud Mohamed Ibrahim, Heba Morad Bahgat, Deena Ahmed Sharshar, Tarek Abdel Azim Ramzy","doi":"10.1186/s43162-024-00284-x","DOIUrl":"https://doi.org/10.1186/s43162-024-00284-x","url":null,"abstract":"","PeriodicalId":510107,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"117 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139781007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}